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The map label for this gene is nuoL [H]

Identifier: 89053685

GI number: 89053685

Start: 1152368

End: 1154503

Strand: Direct

Name: nuoL [H]

Synonym: Jann_1194

Alternate gene names: 89053685

Gene position: 1152368-1154503 (Clockwise)

Preceding gene: 89053684

Following gene: 89053686

Centisome position: 26.69

GC content: 61.19

Gene sequence:

>2136_bases
ATGGAAACGATCCTCCTCTTCGCCCCCCTCGTCGGCGCGCTGATCTGTGGCTTCTCTTGGCGCCTGATCGGCGAACAGGC
GGCTTGCGTTATCGCCACGGGCTTCCTGTTCCTGTCGTGCCTTCTGTCCTGGGTCGTCTTCATCGGCTTCGAGGGAGAGA
CCTACACACGCAGCCTGTTCACCTGGATTGAGTCCGGGACGCTCTTCACCGACTGGGCCATCCGCGTCGACCGTCTGACG
GCGATCATGCTGATCGTGATCACCTCCGTGTCCGCCTTGGTACACCTCTATTCCTTCGGCTACATGGCCCATGACGAGAA
CTTCAAGGAGGGCGAGAGCTACCGCCCAAGGTTCTTCGCCTACCTGTCGTTCTTCACCTTCACCATGCTGATGCTGGTGA
CCGCCGATAACCTTCTGCAGCTGTTCTTCGGCTGGGAAGGCGTGGGCGTCGCGTCCTACCTGTTGATCGGTTTCTACTTC
CGCAAACCCTCCGCAGGCGCGGCGGCGATGAAGGCGTTTATCGTCAACCGCGTGGGGGACTTCGGCTTCCTACTGGGCAT
CTTCGCGCTGTTCTGGATGACGGACTCGATCCAGTTCGACGTCGTGCTTGGCATGGGCGCAGAGCTGGCCGAGATGTCGA
TCATCTTCCTCGGGATGGAGCTGAACGCGGCGGAAACCATCGCCTTCCTGCTGTTCATCGGCGCGATGGGCAAGTCGGCG
CAGTTGTTGCTGCACGTCTGGCTGCCCGACGCGATGGAGGGCCCGACGCCCGTGTCGGCCCTGATCCACGCGGCCACCAT
GGTGACGGCGGGCGTCTTCCTTGTCTGCCGCATGTCCCCGGTGATCGAATACGCGCCGCTGGCGGGCAATTTCATCATCA
TCATCGGCGCGCTGTCGGCCTTCGTGGCCGCCACAATCGGCCTGGTGCAGAACGACATCAAGCGCGTGATCGCCTATTCG
ACGATGTCCCAGCTTGGCTACATGTTCGTCGCCGCGGGCGTCGGCGTCTATTCGGTCGCGATGTTCCACCTGCTGACCCA
CGCGTTTTTCAAGGCGATGCTGTTTTTAGGCGCGGGTTCGGTCATCCACGCGATGCACCATGAGCAGGACATGCGGAACT
ATGGCGGGCTGCGGAAGAAGATCCCCTACACGTTCTGGGCGATGATGATCGGCACTTTGGCGATCACCGGCGTGGGTATC
CCGCTGCTTTACGTCGGTTTCCCGGTCGGCTTCGCGGGCTTCGTGTCCAAGGATGCGGTGATCGAGAGCGCCTATGCCTT
CGGCGGAGACCTCGGCCAATTCGCCTTCTGGGCGTTGGTCATCGGCGCGCTGTTCACCAGCTTCTACTCCTGGCGCCTGA
TGTTCCTGACCTTCTACGGCGAGGCGCGCGGCAACAAGCACACCCATGAACACGCTCATGAGAGCCCGATGACCATGCTG
ATCCCACTGGGTGCGCTGGCCATTGGCGCGGTCGTGGCGGGTATGGTTTGGTATGGCAGTTTCTTCGGCAAAACCAATTA
TGTGGCTCAGTTCTTCGGCGTGCCCTACGCGGTGGAAGAAGCCCATGGCGACGAGCACGCAGATGATCACAGCGGCGAGG
ACGCGCATGGCGCGGAGGAGCAGGCTGAAGACCACGCAGCCGGGGGCGGACACGGCGACGACCCCCATTACGTCTTCACC
GGCGCACCCGGAGAGGGCGCGATCCACCACGCCCCCGACAACCACGTTCTGAACGACGCGCACTCCGTTCCAAACTGGGT
GAAGGTCGCCCCGTTCGTTGCAATGGTTCTGGGTTTTGCCACGGCCTACCTGTTCTACATCCTGAAACCGTCGATCCCCG
GTCGCCTCGCGACACAACAAAAGCCGCTCTACAATTTCCTTTTGAACAAATGGTACTTTGACGAAGCCTATGAGTACCTG
TTTATCAAGCCCGCCCAATGGCTTGGCCGGTTCCTGTGGAAGCGCGGCGACACAAACACGATTGACGGCAGCATCAACGG
GCTGGCGATGGGGATCATCCCCTTCTTCACCCGCCTCGCGGGCCGCGCGCAATCCGGCTACATTTTCCATTACGCGTTCG
CGATGGTGCTGGGGCTTGTCGCCATCATCATCTTCGTCACGTTGAGCGCGGGGTAA

Upstream 100 bases:

>100_bases
GGATCCTGGATCGCCATCGGCATCCCAATCGCCATAGCCATCGGGCTGGTGCTGTACTTCGCGATTGCCAAAAACGACAC
CGACAAGCGGGACTGACGCA

Downstream 100 bases:

>100_bases
GGCATCATGGATAACCTCATCTCCATCGTCACATTCCTGCCCCTGGTGGCCGCGATCATCATGGCCGTGTTCCTGCGCGG
CGAGGATGAGGCCGCGCAGT

Product: NADH dehydrogenase subunit L

Products: NA

Alternate protein names: NADH dehydrogenase I subunit L; NDH-1 subunit L [H]

Number of amino acids: Translated: 711; Mature: 711

Protein sequence:

>711_residues
METILLFAPLVGALICGFSWRLIGEQAACVIATGFLFLSCLLSWVVFIGFEGETYTRSLFTWIESGTLFTDWAIRVDRLT
AIMLIVITSVSALVHLYSFGYMAHDENFKEGESYRPRFFAYLSFFTFTMLMLVTADNLLQLFFGWEGVGVASYLLIGFYF
RKPSAGAAAMKAFIVNRVGDFGFLLGIFALFWMTDSIQFDVVLGMGAELAEMSIIFLGMELNAAETIAFLLFIGAMGKSA
QLLLHVWLPDAMEGPTPVSALIHAATMVTAGVFLVCRMSPVIEYAPLAGNFIIIIGALSAFVAATIGLVQNDIKRVIAYS
TMSQLGYMFVAAGVGVYSVAMFHLLTHAFFKAMLFLGAGSVIHAMHHEQDMRNYGGLRKKIPYTFWAMMIGTLAITGVGI
PLLYVGFPVGFAGFVSKDAVIESAYAFGGDLGQFAFWALVIGALFTSFYSWRLMFLTFYGEARGNKHTHEHAHESPMTML
IPLGALAIGAVVAGMVWYGSFFGKTNYVAQFFGVPYAVEEAHGDEHADDHSGEDAHGAEEQAEDHAAGGGHGDDPHYVFT
GAPGEGAIHHAPDNHVLNDAHSVPNWVKVAPFVAMVLGFATAYLFYILKPSIPGRLATQQKPLYNFLLNKWYFDEAYEYL
FIKPAQWLGRFLWKRGDTNTIDGSINGLAMGIIPFFTRLAGRAQSGYIFHYAFAMVLGLVAIIIFVTLSAG

Sequences:

>Translated_711_residues
METILLFAPLVGALICGFSWRLIGEQAACVIATGFLFLSCLLSWVVFIGFEGETYTRSLFTWIESGTLFTDWAIRVDRLT
AIMLIVITSVSALVHLYSFGYMAHDENFKEGESYRPRFFAYLSFFTFTMLMLVTADNLLQLFFGWEGVGVASYLLIGFYF
RKPSAGAAAMKAFIVNRVGDFGFLLGIFALFWMTDSIQFDVVLGMGAELAEMSIIFLGMELNAAETIAFLLFIGAMGKSA
QLLLHVWLPDAMEGPTPVSALIHAATMVTAGVFLVCRMSPVIEYAPLAGNFIIIIGALSAFVAATIGLVQNDIKRVIAYS
TMSQLGYMFVAAGVGVYSVAMFHLLTHAFFKAMLFLGAGSVIHAMHHEQDMRNYGGLRKKIPYTFWAMMIGTLAITGVGI
PLLYVGFPVGFAGFVSKDAVIESAYAFGGDLGQFAFWALVIGALFTSFYSWRLMFLTFYGEARGNKHTHEHAHESPMTML
IPLGALAIGAVVAGMVWYGSFFGKTNYVAQFFGVPYAVEEAHGDEHADDHSGEDAHGAEEQAEDHAAGGGHGDDPHYVFT
GAPGEGAIHHAPDNHVLNDAHSVPNWVKVAPFVAMVLGFATAYLFYILKPSIPGRLATQQKPLYNFLLNKWYFDEAYEYL
FIKPAQWLGRFLWKRGDTNTIDGSINGLAMGIIPFFTRLAGRAQSGYIFHYAFAMVLGLVAIIIFVTLSAG
>Mature_711_residues
METILLFAPLVGALICGFSWRLIGEQAACVIATGFLFLSCLLSWVVFIGFEGETYTRSLFTWIESGTLFTDWAIRVDRLT
AIMLIVITSVSALVHLYSFGYMAHDENFKEGESYRPRFFAYLSFFTFTMLMLVTADNLLQLFFGWEGVGVASYLLIGFYF
RKPSAGAAAMKAFIVNRVGDFGFLLGIFALFWMTDSIQFDVVLGMGAELAEMSIIFLGMELNAAETIAFLLFIGAMGKSA
QLLLHVWLPDAMEGPTPVSALIHAATMVTAGVFLVCRMSPVIEYAPLAGNFIIIIGALSAFVAATIGLVQNDIKRVIAYS
TMSQLGYMFVAAGVGVYSVAMFHLLTHAFFKAMLFLGAGSVIHAMHHEQDMRNYGGLRKKIPYTFWAMMIGTLAITGVGI
PLLYVGFPVGFAGFVSKDAVIESAYAFGGDLGQFAFWALVIGALFTSFYSWRLMFLTFYGEARGNKHTHEHAHESPMTML
IPLGALAIGAVVAGMVWYGSFFGKTNYVAQFFGVPYAVEEAHGDEHADDHSGEDAHGAEEQAEDHAAGGGHGDDPHYVFT
GAPGEGAIHHAPDNHVLNDAHSVPNWVKVAPFVAMVLGFATAYLFYILKPSIPGRLATQQKPLYNFLLNKWYFDEAYEYL
FIKPAQWLGRFLWKRGDTNTIDGSINGLAMGIIPFFTRLAGRAQSGYIFHYAFAMVLGLVAIIIFVTLSAG

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1009

COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit

Gene ontology:

Cell location: Cellular chromatophore membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=461, Percent_Identity=38.8286334056399, Blast_Score=287, Evalue=2e-77,
Organism=Escherichia coli, GI1788614, Length=502, Percent_Identity=40.6374501992032, Blast_Score=332, Evalue=7e-92,
Organism=Escherichia coli, GI1788829, Length=495, Percent_Identity=27.8787878787879, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI1788827, Length=441, Percent_Identity=28.7981859410431, Blast_Score=119, Evalue=8e-28,
Organism=Escherichia coli, GI1788831, Length=346, Percent_Identity=30.3468208092486, Blast_Score=119, Evalue=9e-28,
Organism=Escherichia coli, GI2367154, Length=225, Percent_Identity=30.2222222222222, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1788613, Length=459, Percent_Identity=24.6187363834423, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI145693160, Length=300, Percent_Identity=27, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR001516
- InterPro:   IPR003945
- InterPro:   IPR018393 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF00662 Oxidored_q1_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 77980; Mature: 77980

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METILLFAPLVGALICGFSWRLIGEQAACVIATGFLFLSCLLSWVVFIGFEGETYTRSLF
CCCEEHHHHHHHHHHHCCHHEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
TWIESGTLFTDWAIRVDRLTAIMLIVITSVSALVHLYSFGYMAHDENFKEGESYRPRFFA
HHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHH
YLSFFTFTMLMLVTADNLLQLFFGWEGVGVASYLLIGFYFRKPSAGAAAMKAFIVNRVGD
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCH
FGFLLGIFALFWMTDSIQFDVVLGMGAELAEMSIIFLGMELNAAETIAFLLFIGAMGKSA
HHHHHHHHHHHHHCCCCEEEEEECCCCHHHHEEEEEEEEECCHHHHHHHHHHHHCCCCCC
QLLLHVWLPDAMEGPTPVSALIHAATMVTAGVFLVCRMSPVIEYAPLAGNFIIIIGALSA
EEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCEEHHHHHHH
FVAATIGLVQNDIKRVIAYSTMSQLGYMFVAAGVGVYSVAMFHLLTHAFFKAMLFLGAGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
VIHAMHHEQDMRNYGGLRKKIPYTFWAMMIGTLAITGVGIPLLYVGFPVGFAGFVSKDAV
HHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHH
IESAYAFGGDLGQFAFWALVIGALFTSFYSWRLMFLTFYGEARGNKHTHEHAHESPMTML
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHCCCCCEEE
IPLGALAIGAVVAGMVWYGSFFGKTNYVAQFFGVPYAVEEAHGDEHADDHSGEDAHGAEE
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEHHCCCCCCCCCCCCCCCCCCHH
QAEDHAAGGGHGDDPHYVFTGAPGEGAIHHAPDNHVLNDAHSVPNWVKVAPFVAMVLGFA
HHHHCCCCCCCCCCCCEEEECCCCCCCEEECCCCCCCCCHHCCCCHHHHHHHHHHHHHHH
TAYLFYILKPSIPGRLATQQKPLYNFLLNKWYFDEAYEYLFIKPAQWLGRFLWKRGDTNT
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHEEEEEHHHHHHHHHHHCCCCCE
IDGSINGLAMGIIPFFTRLAGRAQSGYIFHYAFAMVLGLVAIIIFVTLSAG
ECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
METILLFAPLVGALICGFSWRLIGEQAACVIATGFLFLSCLLSWVVFIGFEGETYTRSLF
CCCEEHHHHHHHHHHHCCHHEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
TWIESGTLFTDWAIRVDRLTAIMLIVITSVSALVHLYSFGYMAHDENFKEGESYRPRFFA
HHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHH
YLSFFTFTMLMLVTADNLLQLFFGWEGVGVASYLLIGFYFRKPSAGAAAMKAFIVNRVGD
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCH
FGFLLGIFALFWMTDSIQFDVVLGMGAELAEMSIIFLGMELNAAETIAFLLFIGAMGKSA
HHHHHHHHHHHHHCCCCEEEEEECCCCHHHHEEEEEEEEECCHHHHHHHHHHHHCCCCCC
QLLLHVWLPDAMEGPTPVSALIHAATMVTAGVFLVCRMSPVIEYAPLAGNFIIIIGALSA
EEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCEEHHHHHHH
FVAATIGLVQNDIKRVIAYSTMSQLGYMFVAAGVGVYSVAMFHLLTHAFFKAMLFLGAGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
VIHAMHHEQDMRNYGGLRKKIPYTFWAMMIGTLAITGVGIPLLYVGFPVGFAGFVSKDAV
HHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHH
IESAYAFGGDLGQFAFWALVIGALFTSFYSWRLMFLTFYGEARGNKHTHEHAHESPMTML
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHCCCCCEEE
IPLGALAIGAVVAGMVWYGSFFGKTNYVAQFFGVPYAVEEAHGDEHADDHSGEDAHGAEE
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEHHCCCCCCCCCCCCCCCCCCHH
QAEDHAAGGGHGDDPHYVFTGAPGEGAIHHAPDNHVLNDAHSVPNWVKVAPFVAMVLGFA
HHHHCCCCCCCCCCCCEEEECCCCCCCEEECCCCCCCCCHHCCCCHHHHHHHHHHHHHHH
TAYLFYILKPSIPGRLATQQKPLYNFLLNKWYFDEAYEYLFIKPAQWLGRFLWKRGDTNT
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHEEEEEHHHHHHHHHHHCCCCCE
IDGSINGLAMGIIPFFTRLAGRAQSGYIFHYAFAMVLGLVAIIIFVTLSAG
ECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8566820 [H]