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The map label for this gene is ruvB

Identifier: 89053457

GI number: 89053457

Start: 923056

End: 924090

Strand: Direct

Name: ruvB

Synonym: Jann_0966

Alternate gene names: 89053457

Gene position: 923056-924090 (Clockwise)

Preceding gene: 89053456

Following gene: 89053458

Centisome position: 21.38

GC content: 63.96

Gene sequence:

>1035_bases
ATGACGGATTCTGACCCAACCCTGCGCCCTGATCGCTTGCCCGAAGACGTCCAGGCCACCGATGACCGTGCGCTGCGCCC
GCAATCCCTGGATGATTTCACTGGCCAGGAAGAGGCGCGCGCCAATTTGCGCGTGTTCATTGAAAGCGCCCGCAGGCGCG
GCGAGGCGATGGACCACGTCCTCTTCCACGGGCCACCCGGTTTGGGCAAGACGACGCTGGCGCAGATCATGGCGAAGGAA
TTGGGGGTCGGGTTTCGCATGACATCCGGTCCGGTGCTTGCGAAAGCGGGTGATCTGGCCGCGATCCTGACGAACCTTGA
GGCGAAGGACGTGCTGTTCATCGACGAAATTCATCGCCTGAACCCGGTGGTGGAGGAAATTCTATACCCGGCGTTGGAAG
ATTTTGAACTGGATCTGGTGATCGGCGAAGGCCCCGCCGCACGCACTGTGCGCATTGAATTGCAGCCCTTCACGCTGGTC
GGCGCGACCACGCGTCTGGGGCTTTTGACCACGCCTCTGCGCGACCGGTTCGGTATTCCGACCCGCCTGAATTTCTACAC
CATTGCCGAATTGGACCAGATCGTCGCGCGCGGCGCGCGGCTGGCGGGGATTGAGGCCGACCCAAAGGGCACTGCAGAGA
TCGCCAAACGCGCGCGCGGCACGCCACGGATTGCGGGCAGGCTGTTGCGGCGGGTCATCGACTTTGCCGTCGTGGAGGGG
GACGGTCGCCTGACCCAAGGGATCGCTGACAGCGCCTTGACACGGTTGGGGGTGGATGACCTAGGGCTGGACGGGGCGGA
CCGGCGCTATCTGTCGCTGATTGCAGAGAATTATCACGGCGGTCCGGTGGGGATCGAGACGGTTGCGGCGGCATTGGCCG
AGCCACGGGACGCGCTGGAGGAGGTAATCGAGCCGTTCCTGCTGCAACAGGGCCTTATCGCACGCACGCCGCGCGGGCGG
ATGTTGGCGCATAAGGGATGGACGCATCTGGGGATGGCCCCACCGAAGCGTCCGGATCAGGGGGAGCTGATATGA

Upstream 100 bases:

>100_bases
CGCGCGGCCCTGCGGCTTCTGGCCCCGAAAGAGTGACCGGGATGCGTGCGCGTGTCGCCCGTGTGGTCAATGGCCGGTGG
GGTTGCCATAAGGAGGCGAC

Downstream 100 bases:

>100_bases
GATTTGGGTTTGCGTTGGTTTTTGCGTTGTGGACGACAGCCGCTGCAGCGCAGGTCCCGTTCGGGCGCGAGGATGTCGTT
GAGACGCGCTTCGGCAGCCT

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MTDSDPTLRPDRLPEDVQATDDRALRPQSLDDFTGQEEARANLRVFIESARRRGEAMDHVLFHGPPGLGKTTLAQIMAKE
LGVGFRMTSGPVLAKAGDLAAILTNLEAKDVLFIDEIHRLNPVVEEILYPALEDFELDLVIGEGPAARTVRIELQPFTLV
GATTRLGLLTTPLRDRFGIPTRLNFYTIAELDQIVARGARLAGIEADPKGTAEIAKRARGTPRIAGRLLRRVIDFAVVEG
DGRLTQGIADSALTRLGVDDLGLDGADRRYLSLIAENYHGGPVGIETVAAALAEPRDALEEVIEPFLLQQGLIARTPRGR
MLAHKGWTHLGMAPPKRPDQGELI

Sequences:

>Translated_344_residues
MTDSDPTLRPDRLPEDVQATDDRALRPQSLDDFTGQEEARANLRVFIESARRRGEAMDHVLFHGPPGLGKTTLAQIMAKE
LGVGFRMTSGPVLAKAGDLAAILTNLEAKDVLFIDEIHRLNPVVEEILYPALEDFELDLVIGEGPAARTVRIELQPFTLV
GATTRLGLLTTPLRDRFGIPTRLNFYTIAELDQIVARGARLAGIEADPKGTAEIAKRARGTPRIAGRLLRRVIDFAVVEG
DGRLTQGIADSALTRLGVDDLGLDGADRRYLSLIAENYHGGPVGIETVAAALAEPRDALEEVIEPFLLQQGLIARTPRGR
MLAHKGWTHLGMAPPKRPDQGELI
>Mature_343_residues
TDSDPTLRPDRLPEDVQATDDRALRPQSLDDFTGQEEARANLRVFIESARRRGEAMDHVLFHGPPGLGKTTLAQIMAKEL
GVGFRMTSGPVLAKAGDLAAILTNLEAKDVLFIDEIHRLNPVVEEILYPALEDFELDLVIGEGPAARTVRIELQPFTLVG
ATTRLGLLTTPLRDRFGIPTRLNFYTIAELDQIVARGARLAGIEADPKGTAEIAKRARGTPRIAGRLLRRVIDFAVVEGD
GRLTQGIADSALTRLGVDDLGLDGADRRYLSLIAENYHGGPVGIETVAAALAEPRDALEEVIEPFLLQQGLIARTPRGRM
LAHKGWTHLGMAPPKRPDQGELI

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=326, Percent_Identity=58.5889570552147, Blast_Score=395, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_JANSC (Q28TS9)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_508908.1
- ProteinModelPortal:   Q28TS9
- SMR:   Q28TS9
- STRING:   Q28TS9
- GeneID:   3933410
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_0966
- eggNOG:   COG2255
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- PhylomeDB:   Q28TS9
- ProtClustDB:   PRK00080
- BioCyc:   JSP290400:JANN_0966-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR000641
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00819
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 37486; Mature: 37354

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSDPTLRPDRLPEDVQATDDRALRPQSLDDFTGQEEARANLRVFIESARRRGEAMDHV
CCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LFHGPPGLGKTTLAQIMAKELGVGFRMTSGPVLAKAGDLAAILTNLEAKDVLFIDEIHRL
EEECCCCCCHHHHHHHHHHHHCCCEEECCCCCEECCCHHHHHHHCCCCCCCHHHHHHHHH
NPVVEEILYPALEDFELDLVIGEGPAARTVRIELQPFTLVGATTRLGLLTTPLRDRFGIP
HHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECCEEEECCHHHHHHEECCHHHHCCCC
TRLNFYTIAELDQIVARGARLAGIEADPKGTAEIAKRARGTPRIAGRLLRRVIDFAVVEG
CCCCEEEHHHHHHHHHCCCCEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHEECC
DGRLTQGIADSALTRLGVDDLGLDGADRRYLSLIAENYHGGPVGIETVAAALAEPRDALE
CCCHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCHHHHHH
EVIEPFLLQQGLIARTPRGRMLAHKGWTHLGMAPPKRPDQGELI
HHHHHHHHHCCCHHCCCCCCEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TDSDPTLRPDRLPEDVQATDDRALRPQSLDDFTGQEEARANLRVFIESARRRGEAMDHV
CCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LFHGPPGLGKTTLAQIMAKELGVGFRMTSGPVLAKAGDLAAILTNLEAKDVLFIDEIHRL
EEECCCCCCHHHHHHHHHHHHCCCEEECCCCCEECCCHHHHHHHCCCCCCCHHHHHHHHH
NPVVEEILYPALEDFELDLVIGEGPAARTVRIELQPFTLVGATTRLGLLTTPLRDRFGIP
HHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECCEEEECCHHHHHHEECCHHHHCCCC
TRLNFYTIAELDQIVARGARLAGIEADPKGTAEIAKRARGTPRIAGRLLRRVIDFAVVEG
CCCCEEEHHHHHHHHHCCCCEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHEECC
DGRLTQGIADSALTRLGVDDLGLDGADRRYLSLIAENYHGGPVGIETVAAALAEPRDALE
CCCHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCHHHHHH
EVIEPFLLQQGLIARTPRGRMLAHKGWTHLGMAPPKRPDQGELI
HHHHHHHHHCCCHHCCCCCCEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA