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The map label for this gene is ybfB [H]

Identifier: 89053434

GI number: 89053434

Start: 901015

End: 902238

Strand: Direct

Name: ybfB [H]

Synonym: Jann_0943

Alternate gene names: 89053434

Gene position: 901015-902238 (Clockwise)

Preceding gene: 89053432

Following gene: 89053436

Centisome position: 20.87

GC content: 66.42

Gene sequence:

>1224_bases
ATGTCCGAGCCGAGCATCCTTGATACACGCGCGTCCTGGGGCCGTCTGGCGCTGGCGCTTCTGGTGTCGCTCATCGGCAA
TGCGGGGATGTGGGCGATCATCCTGATCCTGCCCGATGTCCAGGCGGAATTCGGCGTCAGCCGGGCGGGCGCCTCGCTGC
CCTATGCCGCGATGATGATCGGCTTTGCCCTCGGCAATTTCCTGATCGGGCGGTGGGTGGACCGGTATGGGCTGGCCGTG
TCACTCGCGGCATCGGCCGTGGTGATGGGTGTGGCTTACGGGGCGGCGTCCGCGGCCCCCTCCCTCGCGGTGCTGTCGCT
CGCGCAGTTTTTCATCGGTTTCGGGGCGGCGGCCAGTTTCGGGCCATTGATTGCCGATGTGTCCCAATGGTTCCTGAAAC
GTCGGGGGCTTGCCGTGGCGATCGCGGCGTCCGGCAATTACCTGTCCGGCGCGCTTTGGCCGATGCTGCTGGCTGGGACG
CTGGCCACCGATGGGTGGCGCATGGCCTGCGTGATCCTGGCCCTAAGTTGCCTGATCGCGATGTTGCCCCTGACCTGGGT
GCTGCGCCGTCGCCTGCCTGAAAGCGCCATGGCCGCGTCTGATGCGGCGGCTGTGGCCCGCGCGCGGACCACCGGCCTCG
GCCCGCGGGCCCTGACGGCGCTGTTGGGGGTGGCGGGGATTGGCTGCTGCGTGGCCATGTCGATGCCCCAGGTTCATATC
GTGGCCTATTGCGTCGACCTCGGATACGGCCCGGCGGTGGGGGCAGAGATGCTGTCGCTGATGCTGCTGTTCGGCGTGGT
ATCGCGGTTGATTTCCGGCGTGATGGCGGATCACCTTGGCGGCGTGGCGACGCTGCTGATCGGCTCAACGCTGCAAATGC
TGGCGCTGTTTCTCTACCTGCCCGCGTCCGGCCTGACATCTTTGTACCTCGTGTCCATGGTCTTTGGTCTCAGCCAGGGG
GGCATCGTGCCATCCTATGCGGTCATCGTGCGCGAGTACCTTCCGGCGCGGGAGGCCGGGGCGCGGGTGGGGTTCGTGAT
CACGACGACGATTGTCGGCATGGCTTTGGGCGGTTGGCTGTCGGGTGTGATCTACGACGTGACGGGATCGTACCAATGGG
CGTTCCTCAACGGGATTGCGTTCAATGCGGTGAACGTGGGCGTCATGGTCTACATCCTGCTGCGATCCCGCCCGCGCGCG
CCTTTTGTGCCAGCGCCCGCGTAG

Upstream 100 bases:

>100_bases
ATTCTCCTTTTCGTGGTGCGACGTTTGACCAGATATCTGCTGAAACGGGAGCGGTACGAATGGCGGTTCCCCCGGGCGGG
CGGCTCCCCTAATCTCAGGC

Downstream 100 bases:

>100_bases
CGCCTTACCAATGCGGCGGCTTTTGGTCTGCCAGCGGGACGGACCCGCTGTTGCCCTCAATCTCCCTCTCCGCCTCTCGC
GACATCAGCATCTCCACTCG

Product: major facilitator transporter

Products: Proton [Cytoplasm]; N-acetylneuraminate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MSEPSILDTRASWGRLALALLVSLIGNAGMWAIILILPDVQAEFGVSRAGASLPYAAMMIGFALGNFLIGRWVDRYGLAV
SLAASAVVMGVAYGAASAAPSLAVLSLAQFFIGFGAAASFGPLIADVSQWFLKRRGLAVAIAASGNYLSGALWPMLLAGT
LATDGWRMACVILALSCLIAMLPLTWVLRRRLPESAMAASDAAAVARARTTGLGPRALTALLGVAGIGCCVAMSMPQVHI
VAYCVDLGYGPAVGAEMLSLMLLFGVVSRLISGVMADHLGGVATLLIGSTLQMLALFLYLPASGLTSLYLVSMVFGLSQG
GIVPSYAVIVREYLPAREAGARVGFVITTTIVGMALGGWLSGVIYDVTGSYQWAFLNGIAFNAVNVGVMVYILLRSRPRA
PFVPAPA

Sequences:

>Translated_407_residues
MSEPSILDTRASWGRLALALLVSLIGNAGMWAIILILPDVQAEFGVSRAGASLPYAAMMIGFALGNFLIGRWVDRYGLAV
SLAASAVVMGVAYGAASAAPSLAVLSLAQFFIGFGAAASFGPLIADVSQWFLKRRGLAVAIAASGNYLSGALWPMLLAGT
LATDGWRMACVILALSCLIAMLPLTWVLRRRLPESAMAASDAAAVARARTTGLGPRALTALLGVAGIGCCVAMSMPQVHI
VAYCVDLGYGPAVGAEMLSLMLLFGVVSRLISGVMADHLGGVATLLIGSTLQMLALFLYLPASGLTSLYLVSMVFGLSQG
GIVPSYAVIVREYLPAREAGARVGFVITTTIVGMALGGWLSGVIYDVTGSYQWAFLNGIAFNAVNVGVMVYILLRSRPRA
PFVPAPA
>Mature_406_residues
SEPSILDTRASWGRLALALLVSLIGNAGMWAIILILPDVQAEFGVSRAGASLPYAAMMIGFALGNFLIGRWVDRYGLAVS
LAASAVVMGVAYGAASAAPSLAVLSLAQFFIGFGAAASFGPLIADVSQWFLKRRGLAVAIAASGNYLSGALWPMLLAGTL
ATDGWRMACVILALSCLIAMLPLTWVLRRRLPESAMAASDAAAVARARTTGLGPRALTALLGVAGIGCCVAMSMPQVHIV
AYCVDLGYGPAVGAEMLSLMLLFGVVSRLISGVMADHLGGVATLLIGSTLQMLALFLYLPASGLTSLYLVSMVFGLSQGG
IVPSYAVIVREYLPAREAGARVGFVITTTIVGMALGGWLSGVIYDVTGSYQWAFLNGIAFNAVNVGVMVYILLRSRPRAP
FVPAPA

Specific function: May Be A Sugar-Cation Symporter Involved In Sialic Acid Transport As It Is Required For Sialic Acid Uptake. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Homo sapiens, GI42475555, Length=304, Percent_Identity=27.3026315789474, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324453, Length=252, Percent_Identity=26.1904761904762, Blast_Score=66, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42242; Mature: 42111

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPSILDTRASWGRLALALLVSLIGNAGMWAIILILPDVQAEFGVSRAGASLPYAAMMI
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHCHHHCCCCCHHHHHHH
GFALGNFLIGRWVDRYGLAVSLAASAVVMGVAYGAASAAPSLAVLSLAQFFIGFGAAASF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHCCHHHH
GPLIADVSQWFLKRRGLAVAIAASGNYLSGALWPMLLAGTLATDGWRMACVILALSCLIA
HHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
MLPLTWVLRRRLPESAMAASDAAAVARARTTGLGPRALTALLGVAGIGCCVAMSMPQVHI
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
VAYCVDLGYGPAVGAEMLSLMLLFGVVSRLISGVMADHLGGVATLLIGSTLQMLALFLYL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PASGLTSLYLVSMVFGLSQGGIVPSYAVIVREYLPAREAGARVGFVITTTIVGMALGGWL
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHH
SGVIYDVTGSYQWAFLNGIAFNAVNVGVMVYILLRSRPRAPFVPAPA
HHHHEECCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SEPSILDTRASWGRLALALLVSLIGNAGMWAIILILPDVQAEFGVSRAGASLPYAAMMI
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHCHHHCCCCCHHHHHHH
GFALGNFLIGRWVDRYGLAVSLAASAVVMGVAYGAASAAPSLAVLSLAQFFIGFGAAASF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHCCHHHH
GPLIADVSQWFLKRRGLAVAIAASGNYLSGALWPMLLAGTLATDGWRMACVILALSCLIA
HHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
MLPLTWVLRRRLPESAMAASDAAAVARARTTGLGPRALTALLGVAGIGCCVAMSMPQVHI
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
VAYCVDLGYGPAVGAEMLSLMLLFGVVSRLISGVMADHLGGVATLLIGSTLQMLALFLYL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PASGLTSLYLVSMVFGLSQGGIVPSYAVIVREYLPAREAGARVGFVITTTIVGMALGGWL
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHH
SGVIYDVTGSYQWAFLNGIAFNAVNVGVMVYILLRSRPRAPFVPAPA
HHHHEECCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; N-acetylneuraminate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + N-acetylneuraminate [Periplasm] = Proton [Cytoplasm] + N-acetylneuraminate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]