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The map label for this gene is iorB [H]

Identifier: 89053366

GI number: 89053366

Start: 830359

End: 832455

Strand: Direct

Name: iorB [H]

Synonym: Jann_0875

Alternate gene names: 89053366

Gene position: 830359-832455 (Clockwise)

Preceding gene: 89053365

Following gene: 89053367

Centisome position: 19.23

GC content: 65.67

Gene sequence:

>2097_bases
ATGAACATGTCGCTGGAAACCAATCCTCTGCCCTCCCAATGGCTGGAGCTGCGGGCGGAGGGGATCGTGCTCAAATCCGG
CAAGGTCGAGATTGGCCAAGGCCTTGGCACCGCGCTTTTGCAGATAGCGGCGGATGCGCTTGAGGTGCCGTTGGATCGCC
TGACGCTGGTGGCAGGTGACACCGCGACGACGCCGGATGAGATGTGGACATCCGCCTCGATCTCCATCGAAGTGGGTGGC
GCGGCGGTCCGGATGATATGCCTTGCCGTGCGGAACCGCGCGCAGATCGCCGCGGCCCGTATCCTGAACGCAGCGCCCGA
TGCTGTCACGCTGACGGATGGTGTGTTCGGGGCTGAGACGTCTGACAGGCGGCTGAGTTACGCGGATTTGCGGGGGGATC
TGGACCTTGGTCGCCCGCTGAACGCGGCGGAGGTCGCATCGGTCAAACCCCGCCCAAATACCGTCGTCGGCACCCCCGTC
CCGCGCCACGACTTGCTGCAAAAGCTGACCGGCGCCGCGTTCATCCACGACATGGACCGCCCCGGCATGTTGCACGGGCG
TGTCCTGCTGCCCGCGCGCCCCGGTGCCCGGCTGGCGCCCTTGGATCTGACCGGGATCGAGGCCCTCCCCGGCGTGCGCC
TTGTCCACCGTGATGGCGATTTCGTGGGTCTTTGCGCCGTGCGCGAGGAACAGGCCATTGCCGCCCTGACCAAGTTGGAG
GCGATGGCGGTCTGGGCCGGCGGCACAGCGCCCGATGCGTCTGACGTTCCTGCGCTGCTGGCGAAATATGATGCGACCGC
CACCGCTGTCGTGCTGCCTGATCCCCTGCCAGACCCCATGCCCGAAGGCGACGATATCAGCCACACGTTCACGCGGCCTT
TTATCGCCCACGCCTCCATCGGATTGTGCTGCGCCATTGCAGAGCCTGACGGTGACGGCCTCCATGTCTGGAGCCATTCG
CAGGGCGTGTTCCCCCTGCGCCGCGCGCTTGCAGCAGCGCTGGATCTGCCGGAAGACGCCGTGCGTGTCACCCATGCCGA
CGGGGCCGGGTGTTACGGGCATAACGGGGCCGATGATGTGGCGCTGGATGCCGCCCTTTTGGCGCGCGCCGCCGGTGCGC
CGGTTCGAGTGGTCTGGACGCGGCAGCAGGAGCTTACCGCTGCGCCCGCCGGTCCCGCGATGTCTGCGCGTTTGACGGCT
TCGCTGGATGAAAGCGGGCGCATCGACCGCTGGACCCACACAGTCAAAAGCTTCACCCACCTGACCCGTCCGGGATGGGG
GGACGGCGTGAACCTGTGTTCCGCGTGGCGTATGGCGCAGCCTAAACAGCAGGCACCCACCGCGGATCCCGGGCAGGTCC
CGTTTGGCGGCGCGGGGTGCCGGAATGCGCCGCCGATCTATAATGTGCCTGCCGTCATCGACTATGCGCTGATCCCGGAC
CGCCCCCTGCGCACCTCAGCCGTGCGGGCCTTGGGGGCGCATCTGAATGTCTTCGCGATTGAGGCGATGATGGATGATCT
GGCCGAGACGGTCGCGGCAGACCCCATCGACTTCCGCCTCAACCACCTGCCAGACCCCCGCGCGCGGCGTGTGCTGGACC
GGGTGCGCGAAATCTCAGACTGGCCACCGGCCCCTTCGGACGGAGAAGCCGGGCGTGGTTTGGGCTTTGCGCGTTACAAG
AATTCCGGCGCTTATTGCGCCATCGTTGCGGACATCGCGCTGGACGCTGAGATCAAGGTCAGCCGCGTGTGGTGCGTGGT
GGATGCGGGCCTTGCCATCAACCCTGACGGACTGCGCAACCAGTTGGAAGGCGGCATCACTCAAGCCATCAGCTTCACCC
TGCATGAGGCGTTGGAGTGGTCCAAAGAGGGATTCCGCGCCGCCGATTGGGACGCCTATCCCATCCTCCGTTTCGATGCC
GTACCGCACGTCCAAACGGATCTGATCGGTGATCCCGAAGACCCGCCTTTGGGCGTTGGGGAATGCACGACCGGGCCCAT
GGCAGCGGCGCTTGGCAATGCGGTAAAGCAAGCGCTTGGCGTTCGGATTTGTGATATGCCGTTGACAGTAGACCGAATTG
CAGCGGCGTTCGTTTAG

Upstream 100 bases:

>100_bases
ACGCCGCGTTGATCGACTATCTGTCGGAGCGCCATCTGTGCCGGTGCGGCACCCATACCCGCATCCTCAGCGCAATCCGG
GACGTGCGGCAGGGTGCGGC

Downstream 100 bases:

>100_bases
ATAGAAAGAAGGCGACATGGCTCAGGCAGCAGAAAAACTCACGGCGGCGTCGGCGATCTATGCAGCGATCAAGAGCGACC
TGCTGCGCGGTATCTTTCCA

Product: molybdopterin binding aldehyde oxidase and xanthine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 698; Mature: 698

Protein sequence:

>698_residues
MNMSLETNPLPSQWLELRAEGIVLKSGKVEIGQGLGTALLQIAADALEVPLDRLTLVAGDTATTPDEMWTSASISIEVGG
AAVRMICLAVRNRAQIAAARILNAAPDAVTLTDGVFGAETSDRRLSYADLRGDLDLGRPLNAAEVASVKPRPNTVVGTPV
PRHDLLQKLTGAAFIHDMDRPGMLHGRVLLPARPGARLAPLDLTGIEALPGVRLVHRDGDFVGLCAVREEQAIAALTKLE
AMAVWAGGTAPDASDVPALLAKYDATATAVVLPDPLPDPMPEGDDISHTFTRPFIAHASIGLCCAIAEPDGDGLHVWSHS
QGVFPLRRALAAALDLPEDAVRVTHADGAGCYGHNGADDVALDAALLARAAGAPVRVVWTRQQELTAAPAGPAMSARLTA
SLDESGRIDRWTHTVKSFTHLTRPGWGDGVNLCSAWRMAQPKQQAPTADPGQVPFGGAGCRNAPPIYNVPAVIDYALIPD
RPLRTSAVRALGAHLNVFAIEAMMDDLAETVAADPIDFRLNHLPDPRARRVLDRVREISDWPPAPSDGEAGRGLGFARYK
NSGAYCAIVADIALDAEIKVSRVWCVVDAGLAINPDGLRNQLEGGITQAISFTLHEALEWSKEGFRAADWDAYPILRFDA
VPHVQTDLIGDPEDPPLGVGECTTGPMAAALGNAVKQALGVRICDMPLTVDRIAAAFV

Sequences:

>Translated_698_residues
MNMSLETNPLPSQWLELRAEGIVLKSGKVEIGQGLGTALLQIAADALEVPLDRLTLVAGDTATTPDEMWTSASISIEVGG
AAVRMICLAVRNRAQIAAARILNAAPDAVTLTDGVFGAETSDRRLSYADLRGDLDLGRPLNAAEVASVKPRPNTVVGTPV
PRHDLLQKLTGAAFIHDMDRPGMLHGRVLLPARPGARLAPLDLTGIEALPGVRLVHRDGDFVGLCAVREEQAIAALTKLE
AMAVWAGGTAPDASDVPALLAKYDATATAVVLPDPLPDPMPEGDDISHTFTRPFIAHASIGLCCAIAEPDGDGLHVWSHS
QGVFPLRRALAAALDLPEDAVRVTHADGAGCYGHNGADDVALDAALLARAAGAPVRVVWTRQQELTAAPAGPAMSARLTA
SLDESGRIDRWTHTVKSFTHLTRPGWGDGVNLCSAWRMAQPKQQAPTADPGQVPFGGAGCRNAPPIYNVPAVIDYALIPD
RPLRTSAVRALGAHLNVFAIEAMMDDLAETVAADPIDFRLNHLPDPRARRVLDRVREISDWPPAPSDGEAGRGLGFARYK
NSGAYCAIVADIALDAEIKVSRVWCVVDAGLAINPDGLRNQLEGGITQAISFTLHEALEWSKEGFRAADWDAYPILRFDA
VPHVQTDLIGDPEDPPLGVGECTTGPMAAALGNAVKQALGVRICDMPLTVDRIAAAFV
>Mature_698_residues
MNMSLETNPLPSQWLELRAEGIVLKSGKVEIGQGLGTALLQIAADALEVPLDRLTLVAGDTATTPDEMWTSASISIEVGG
AAVRMICLAVRNRAQIAAARILNAAPDAVTLTDGVFGAETSDRRLSYADLRGDLDLGRPLNAAEVASVKPRPNTVVGTPV
PRHDLLQKLTGAAFIHDMDRPGMLHGRVLLPARPGARLAPLDLTGIEALPGVRLVHRDGDFVGLCAVREEQAIAALTKLE
AMAVWAGGTAPDASDVPALLAKYDATATAVVLPDPLPDPMPEGDDISHTFTRPFIAHASIGLCCAIAEPDGDGLHVWSHS
QGVFPLRRALAAALDLPEDAVRVTHADGAGCYGHNGADDVALDAALLARAAGAPVRVVWTRQQELTAAPAGPAMSARLTA
SLDESGRIDRWTHTVKSFTHLTRPGWGDGVNLCSAWRMAQPKQQAPTADPGQVPFGGAGCRNAPPIYNVPAVIDYALIPD
RPLRTSAVRALGAHLNVFAIEAMMDDLAETVAADPIDFRLNHLPDPRARRVLDRVREISDWPPAPSDGEAGRGLGFARYK
NSGAYCAIVADIALDAEIKVSRVWCVVDAGLAINPDGLRNQLEGGITQAISFTLHEALEWSKEGFRAADWDAYPILRFDA
VPHVQTDLIGDPEDPPLGVGECTTGPMAAALGNAVKQALGVRICDMPLTVDRIAAAFV

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012368
- InterPro:   IPR006311 [H]

Pfam domain/function: PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 73833; Mature: 73833

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMSLETNPLPSQWLELRAEGIVLKSGKVEIGQGLGTALLQIAADALEVPLDRLTLVAGD
CCCCCCCCCCCHHHHHHHHCCEEEECCCEEECCCHHHHHHHHHHHHHHCCHHHEEEEECC
TATTPDEMWTSASISIEVGGAAVRMICLAVRNRAQIAAARILNAAPDAVTLTDGVFGAET
CCCCHHHHHCCEEEEEEECHHHHHHHHHHHHCHHHHHHHHHHHCCCCCEEEECCCCCCCC
SDRRLSYADLRGDLDLGRPLNAAEVASVKPRPNTVVGTPVPRHDLLQKLTGAAFIHDMDR
CCCEEEHHHCCCCCCCCCCCCHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHEEECCCC
PGMLHGRVLLPARPGARLAPLDLTGIEALPGVRLVHRDGDFVGLCAVREEQAIAALTKLE
CCCEECEEEEECCCCCEECCCCCCCCCCCCCEEEEEECCCEEEEEEECHHHHHHHHHHHH
AMAVWAGGTAPDASDVPALLAKYDATATAVVLPDPLPDPMPEGDDISHTFTRPFIAHASI
EEEEEECCCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHCCCHHHHCCC
GLCCAIAEPDGDGLHVWSHSQGVFPLRRALAAALDLPEDAVRVTHADGAGCYGHNGADDV
CEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCCHHHEEEEECCCCCCCCCCCCCHH
ALDAALLARAAGAPVRVVWTRQQELTAAPAGPAMSARLTASLDESGRIDRWTHTVKSFTH
HHHHHHHHHHCCCCEEEEEECCHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHH
LTRPGWGDGVNLCSAWRMAQPKQQAPTADPGQVPFGGAGCRNAPPIYNVPAVIDYALIPD
HCCCCCCCCHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEEEECCC
RPLRTSAVRALGAHLNVFAIEAMMDDLAETVAADPIDFRLNHLPDPRARRVLDRVREISD
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEHCCCCCCHHHHHHHHHHHHHCC
WPPAPSDGEAGRGLGFARYKNSGAYCAIVADIALDAEIKVSRVWCVVDAGLAINPDGLRN
CCCCCCCCCCCCCCCEEEECCCCCEEEEEEEEEECCEEEEEEEEEEEECCCEECCHHHHH
QLEGGITQAISFTLHEALEWSKEGFRAADWDAYPILRFDAVPHVQTDLIGDPEDPPLGVG
HHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHCCCCCCCCCCCCCC
ECTTGPMAAALGNAVKQALGVRICDMPLTVDRIAAAFV
CCCCCHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHCC
>Mature Secondary Structure
MNMSLETNPLPSQWLELRAEGIVLKSGKVEIGQGLGTALLQIAADALEVPLDRLTLVAGD
CCCCCCCCCCCHHHHHHHHCCEEEECCCEEECCCHHHHHHHHHHHHHHCCHHHEEEEECC
TATTPDEMWTSASISIEVGGAAVRMICLAVRNRAQIAAARILNAAPDAVTLTDGVFGAET
CCCCHHHHHCCEEEEEEECHHHHHHHHHHHHCHHHHHHHHHHHCCCCCEEEECCCCCCCC
SDRRLSYADLRGDLDLGRPLNAAEVASVKPRPNTVVGTPVPRHDLLQKLTGAAFIHDMDR
CCCEEEHHHCCCCCCCCCCCCHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHEEECCCC
PGMLHGRVLLPARPGARLAPLDLTGIEALPGVRLVHRDGDFVGLCAVREEQAIAALTKLE
CCCEECEEEEECCCCCEECCCCCCCCCCCCCEEEEEECCCEEEEEEECHHHHHHHHHHHH
AMAVWAGGTAPDASDVPALLAKYDATATAVVLPDPLPDPMPEGDDISHTFTRPFIAHASI
EEEEEECCCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHCCCHHHHCCC
GLCCAIAEPDGDGLHVWSHSQGVFPLRRALAAALDLPEDAVRVTHADGAGCYGHNGADDV
CEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCCHHHEEEEECCCCCCCCCCCCCHH
ALDAALLARAAGAPVRVVWTRQQELTAAPAGPAMSARLTASLDESGRIDRWTHTVKSFTH
HHHHHHHHHHCCCCEEEEEECCHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHH
LTRPGWGDGVNLCSAWRMAQPKQQAPTADPGQVPFGGAGCRNAPPIYNVPAVIDYALIPD
HCCCCCCCCHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEEEECCC
RPLRTSAVRALGAHLNVFAIEAMMDDLAETVAADPIDFRLNHLPDPRARRVLDRVREISD
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEHCCCCCCHHHHHHHHHHHHHCC
WPPAPSDGEAGRGLGFARYKNSGAYCAIVADIALDAEIKVSRVWCVVDAGLAINPDGLRN
CCCCCCCCCCCCCCCEEEECCCCCEEEEEEEEEECCEEEEEEEEEEEECCCEECCHHHHH
QLEGGITQAISFTLHEALEWSKEGFRAADWDAYPILRFDAVPHVQTDLIGDPEDPPLGVG
HHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHCCCCCCCCCCCCCC
ECTTGPMAAALGNAVKQALGVRICDMPLTVDRIAAAFV
CCCCCHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]