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The map label for this gene is iorA [H]

Identifier: 89053365

GI number: 89053365

Start: 829913

End: 830362

Strand: Direct

Name: iorA [H]

Synonym: Jann_0874

Alternate gene names: 89053365

Gene position: 829913-830362 (Clockwise)

Preceding gene: 89053364

Following gene: 89053366

Centisome position: 19.22

GC content: 61.56

Gene sequence:

>450_bases
ATGGTGGCGCTGAGGGTCAATGGCGAGGCAATCGATGTGGACGTGGATGAGGCGACGCCGCTTTTGTTCGTGTTGCGCAA
TGATCTTGGGCTGAAAGGGGCCAAGCTTGGCTGTGGTACGGGCCATTGCGGGGCCTGCACGGTTCAGGTCGATGGCCATT
CGGTCAATGCCTGCACCACGCCGCTTTGGTCTGTTGCTGATAAGTCGGTCACGACCGTCGAGGGATGCGGTCAAGACGCT
CTGCTGCAGGCGTTTATCGATCATCAGGCTGCGCAATGCGGCTACTGCATCCCCGGTATCCTCATGGGTGTGCGTGCCTT
TATGGCGCAGACGCCCGATGCCGATGACGCCGCGTTGATCGACTATCTGTCGGAGCGCCATCTGTGCCGGTGCGGCACCC
ATACCCGCATCCTCAGCGCAATCCGGGACGTGCGGCAGGGTGCGGCATGA

Upstream 100 bases:

>100_bases
GCAAGAAATTCCTCGCCTCTGACATGTTCGCGGACGGCACCTGGAACTGGTATATGCGTACGATGGCACGCCGGGGCCTT
CTGGACGGCGCGTCTGAGTG

Downstream 100 bases:

>100_bases
ACATGTCGCTGGAAACCAATCCTCTGCCCTCCCAATGGCTGGAGCTGCGGGCGGAGGGGATCGTGCTCAAATCCGGCAAG
GTCGAGATTGGCCAAGGCCT

Product: (2Fe-2S)-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MVALRVNGEAIDVDVDEATPLLFVLRNDLGLKGAKLGCGTGHCGACTVQVDGHSVNACTTPLWSVADKSVTTVEGCGQDA
LLQAFIDHQAAQCGYCIPGILMGVRAFMAQTPDADDAALIDYLSERHLCRCGTHTRILSAIRDVRQGAA

Sequences:

>Translated_149_residues
MVALRVNGEAIDVDVDEATPLLFVLRNDLGLKGAKLGCGTGHCGACTVQVDGHSVNACTTPLWSVADKSVTTVEGCGQDA
LLQAFIDHQAAQCGYCIPGILMGVRAFMAQTPDADDAALIDYLSERHLCRCGTHTRILSAIRDVRQGAA
>Mature_149_residues
MVALRVNGEAIDVDVDEATPLLFVLRNDLGLKGAKLGCGTGHCGACTVQVDGHSVNACTTPLWSVADKSVTTVEGCGQDA
LLQAFIDHQAAQCGYCIPGILMGVRAFMAQTPDADDAALIDYLSERHLCRCGTHTRILSAIRDVRQGAA

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=153, Percent_Identity=35.9477124183007, Blast_Score=67, Evalue=8e-12,
Organism=Escherichia coli, GI1786480, Length=160, Percent_Identity=37.5, Blast_Score=94, Evalue=5e-21,
Organism=Escherichia coli, GI1789232, Length=147, Percent_Identity=31.9727891156463, Blast_Score=74, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17539860, Length=155, Percent_Identity=36.1290322580645, Blast_Score=89, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI32566215, Length=155, Percent_Identity=35.4838709677419, Blast_Score=89, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17540638, Length=150, Percent_Identity=34.6666666666667, Blast_Score=86, Evalue=6e-18,
Organism=Drosophila melanogaster, GI17737937, Length=159, Percent_Identity=37.1069182389937, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 15685; Mature: 15685

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
6.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVALRVNGEAIDVDVDEATPLLFVLRNDLGLKGAKLGCGTGHCGACTVQVDGHSVNACTT
CEEEEECCEEEEEECCCCCCEEEEEECCCCCCCCEECCCCCCCCEEEEEECCCCCCCCCC
PLWSVADKSVTTVEGCGQDALLQAFIDHQAAQCGYCIPGILMGVRAFMAQTPDADDAALI
CHHHHCCCCCEEHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHH
DYLSERHLCRCGTHTRILSAIRDVRQGAA
HHHHHCCHHHCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVALRVNGEAIDVDVDEATPLLFVLRNDLGLKGAKLGCGTGHCGACTVQVDGHSVNACTT
CEEEEECCEEEEEECCCCCCEEEEEECCCCCCCCEECCCCCCCCEEEEEECCCCCCCCCC
PLWSVADKSVTTVEGCGQDALLQAFIDHQAAQCGYCIPGILMGVRAFMAQTPDADDAALI
CHHHHCCCCCEEHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHH
DYLSERHLCRCGTHTRILSAIRDVRQGAA
HHHHHCCHHHCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]