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The map label for this gene is iolS [H]

Identifier: 89053291

GI number: 89053291

Start: 761361

End: 762332

Strand: Direct

Name: iolS [H]

Synonym: Jann_0800

Alternate gene names: 89053291

Gene position: 761361-762332 (Clockwise)

Preceding gene: 89053290

Following gene: 89053294

Centisome position: 17.63

GC content: 64.51

Gene sequence:

>972_bases
GTGAGGCCGCTGGCGGGACATGCGGTGGGGCCGATTGGCCTGGGCTGCATGAGCTTCGGTGGCATTTACGGGGCCACGAA
TGAAGAAGAGAGTTTCGCCTGCATGCAGGCGGCGCTCGACCTTGGCATCACCCATTGGGATGTCGCCGAGATCTATGGTG
AGGGCGTCTGTGAAACCGTTCTTGGCCGGTTCCTGGCGCAAAGCGGCGCGGATGTGACCCTGGCCACCAAAGCCGGAATC
TACCGGGAGCCGACCCGTCATTTCAGCAATGCCAGCGACCGCCTGCGCGCGTCCCTTGAAGGATCGCTGGAGCGGCTGGG
GCGATCGTCGGTGGAGCTGTTCTACATCCACCGGCGCGACCATTCGATTGAGATCGAAGCGGTCATGGAAACGATGGTGG
GCTTCATGGACGAGGGTCTGATCGGCGGCATCGGGTTGTCGGAGATTGCGCCCGCGACGTTGCGGCGGGCCGTGGCGGTC
GGCCCCGTGGCGGCGGTGCAATCGGAATATTCGCTGTGGACCCGCCAGCCGGAGTTGGGGATGCTGCAAGCCACGGCGGA
GGTGGGCGCGGCGTTTGTGGCGTTCTCACCGCTGGGGCGTGGGATATTGTCCGATCATTTCGCCGGGCGAGAGAGCTTCC
CAAAGGGAGATTTCCGCGCCGGGCAACCGAGGTTTCAGGACCCGAATTACCGCTACAACTTGGGCGCGGTGGAGGGCTTC
AAGGCGTTCTGCGCCACCCGTGGTTGGTCCACGGCGGCCTGCGCATTGGCCTGGGTTCTGGCGCAGGGGGAACATGTGAT
TGCCATCCCCGGCACGCGAACGGCGGCGCATCTAGGTGAGTTGGCTTTGGGTGCGGAGATCGGTTTGAGCACCGAGGATC
TGGCGGAGATCGAACGGGTTTTGCCTGCAGGGTTCGCCCATGGGGCCCGCTACAGTGATGCGCAATGGCCCGCGGTGGAG
AGCTACGGGTAG

Upstream 100 bases:

>100_bases
CCGTGTCCGACCATTTGCTGACGGAGGAGGCGTTGCCTTCGGAAGAGCGTCAGTCGAGCTTCTCGGACATGGTGGAGATC
GCGCTGGAAGCGGCGTTTTC

Downstream 100 bases:

>100_bases
CCCTGCGCGTTCGGTCTATCGACGCGCTATGAGTTGTATTTGCCCAGATGAAACAGGGAGCGGCGTGCCCGCAGGCCCGG
TGGCGCGTTAACCTTAATGG

Product: aldo/keto reductase

Products: NA

Alternate protein names: AKR11A; Vegetative protein 147; VEG147 [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MRPLAGHAVGPIGLGCMSFGGIYGATNEEESFACMQAALDLGITHWDVAEIYGEGVCETVLGRFLAQSGADVTLATKAGI
YREPTRHFSNASDRLRASLEGSLERLGRSSVELFYIHRRDHSIEIEAVMETMVGFMDEGLIGGIGLSEIAPATLRRAVAV
GPVAAVQSEYSLWTRQPELGMLQATAEVGAAFVAFSPLGRGILSDHFAGRESFPKGDFRAGQPRFQDPNYRYNLGAVEGF
KAFCATRGWSTAACALAWVLAQGEHVIAIPGTRTAAHLGELALGAEIGLSTEDLAEIERVLPAGFAHGARYSDAQWPAVE
SYG

Sequences:

>Translated_323_residues
MRPLAGHAVGPIGLGCMSFGGIYGATNEEESFACMQAALDLGITHWDVAEIYGEGVCETVLGRFLAQSGADVTLATKAGI
YREPTRHFSNASDRLRASLEGSLERLGRSSVELFYIHRRDHSIEIEAVMETMVGFMDEGLIGGIGLSEIAPATLRRAVAV
GPVAAVQSEYSLWTRQPELGMLQATAEVGAAFVAFSPLGRGILSDHFAGRESFPKGDFRAGQPRFQDPNYRYNLGAVEGF
KAFCATRGWSTAACALAWVLAQGEHVIAIPGTRTAAHLGELALGAEIGLSTEDLAEIERVLPAGFAHGARYSDAQWPAVE
SYG
>Mature_323_residues
MRPLAGHAVGPIGLGCMSFGGIYGATNEEESFACMQAALDLGITHWDVAEIYGEGVCETVLGRFLAQSGADVTLATKAGI
YREPTRHFSNASDRLRASLEGSLERLGRSSVELFYIHRRDHSIEIEAVMETMVGFMDEGLIGGIGLSEIAPATLRRAVAV
GPVAAVQSEYSLWTRQPELGMLQATAEVGAAFVAFSPLGRGILSDHFAGRESFPKGDFRAGQPRFQDPNYRYNLGAVEGF
KAFCATRGWSTAACALAWVLAQGEHVIAIPGTRTAAHLGELALGAEIGLSTEDLAEIERVLPAGFAHGARYSDAQWPAVE
SYG

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI223718702, Length=221, Percent_Identity=31.6742081447964, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI41152114, Length=203, Percent_Identity=33.0049261083744, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI27436969, Length=316, Percent_Identity=24.6835443037975, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI4504825, Length=316, Percent_Identity=24.6835443037975, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI27436962, Length=216, Percent_Identity=26.3888888888889, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI41327764, Length=178, Percent_Identity=30.8988764044944, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI27436964, Length=216, Percent_Identity=26.3888888888889, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI27436966, Length=216, Percent_Identity=26.3888888888889, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI27436971, Length=319, Percent_Identity=24.4514106583072, Blast_Score=65, Evalue=1e-10,
Organism=Escherichia coli, GI1789375, Length=303, Percent_Identity=28.3828382838284, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87081735, Length=303, Percent_Identity=28.3828382838284, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1787674, Length=308, Percent_Identity=26.2987012987013, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788070, Length=300, Percent_Identity=25.3333333333333, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1789199, Length=336, Percent_Identity=24.702380952381, Blast_Score=68, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6325384, Length=332, Percent_Identity=24.0963855421687, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323998, Length=323, Percent_Identity=23.5294117647059, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 34467; Mature: 34467

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPLAGHAVGPIGLGCMSFGGIYGATNEEESFACMQAALDLGITHWDVAEIYGEGVCETV
CCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHH
LGRFLAQSGADVTLATKAGIYREPTRHFSNASDRLRASLEGSLERLGRSSVELFYIHRRD
HHHHHHCCCCCEEEEECCCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECC
HSIEIEAVMETMVGFMDEGLIGGIGLSEIAPATLRRAVAVGPVAAVQSEYSLWTRQPELG
CCCHHHHHHHHHHHHHHCCCCCCCCHHHHCHHHHHHHHHHCHHHHHHHHHHHHCCCCCCC
MLQATAEVGAAFVAFSPLGRGILSDHFAGRESFPKGDFRAGQPRFQDPNYRYNLGAVEGF
HHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEECCCHHHH
KAFCATRGWSTAACALAWVLAQGEHVIAIPGTRTAAHLGELALGAEIGLSTEDLAEIERV
HHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCHHCCCCHHHHHHHHHH
LPAGFAHGARYSDAQWPAVESYG
HHCHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRPLAGHAVGPIGLGCMSFGGIYGATNEEESFACMQAALDLGITHWDVAEIYGEGVCETV
CCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHH
LGRFLAQSGADVTLATKAGIYREPTRHFSNASDRLRASLEGSLERLGRSSVELFYIHRRD
HHHHHHCCCCCEEEEECCCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECC
HSIEIEAVMETMVGFMDEGLIGGIGLSEIAPATLRRAVAVGPVAAVQSEYSLWTRQPELG
CCCHHHHHHHHHHHHHHCCCCCCCCHHHHCHHHHHHHHHHCHHHHHHHHHHHHCCCCCCC
MLQATAEVGAAFVAFSPLGRGILSDHFAGRESFPKGDFRAGQPRFQDPNYRYNLGAVEGF
HHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEECCCHHHH
KAFCATRGWSTAACALAWVLAQGEHVIAIPGTRTAAHLGELALGAEIGLSTEDLAEIERV
HHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCHHCCCCHHHHHHHHHH
LPAGFAHGARYSDAQWPAVESYG
HHCHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584049; 9384377; 9298659 [H]