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The map label for this gene is iscU [H]

Identifier: 88658479

GI number: 88658479

Start: 637893

End: 638306

Strand: Direct

Name: iscU [H]

Synonym: ECH_0630

Alternate gene names: 88658479

Gene position: 637893-638306 (Clockwise)

Preceding gene: 88658103

Following gene: 88657844

Centisome position: 54.23

GC content: 34.3

Gene sequence:

>414_bases
ATGAGTTATAGTGAATCTCTTCTAGAGCATTACAAAAATCCTAAAAACGTCGGTACTCTACCTAAAGAAGATTATAATGT
AGGAACTGGACTAGTAGGAGCTCCAAGCTGTGGAGATGTAATGAAGTTACAAATAAAAGTAGATGATAATGGTAAAATCA
TTGATGCAAAGTTTAAAACTTTCGGATGTGGAGCCGCAATTGCAGCAAGTTCTTTAGCAACAGAGCTAATAAAAGGTAAG
ACAATAGATGAAGCACATCAATTAAAAAATACTGTTTTAGCAAAAGAATTAAGCCTGCCTCCAGTAAAGATACATTGTTC
TTTACTTGCAGAAGATGCTGTAAAAGCTGCCATAAAGGATTATAACATGAAGCAAGCAACCAAAAAAGACAAGCTTTCAT
CTTCAAATGAATAG

Upstream 100 bases:

>100_bases
CCATTATGGGAAATGGTCCAAGAAGGTGTAGACCTTAATAATATCAAATGGGATGCACATTGATTATGTTATTATATTGT
CGTAATTATGAGGTAATTTT

Downstream 100 bases:

>100_bases
ATATCTATTAAAGTAAGGTTTACATATGATGAATAGTGAAACTCCTACATTTTATAATAGTGAAGACAGTGAAGATAATT
CATGCAGTTCACAGATCAAG

Product: scaffold protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 137; Mature: 136

Protein sequence:

>137_residues
MSYSESLLEHYKNPKNVGTLPKEDYNVGTGLVGAPSCGDVMKLQIKVDDNGKIIDAKFKTFGCGAAIAASSLATELIKGK
TIDEAHQLKNTVLAKELSLPPVKIHCSLLAEDAVKAAIKDYNMKQATKKDKLSSSNE

Sequences:

>Translated_137_residues
MSYSESLLEHYKNPKNVGTLPKEDYNVGTGLVGAPSCGDVMKLQIKVDDNGKIIDAKFKTFGCGAAIAASSLATELIKGK
TIDEAHQLKNTVLAKELSLPPVKIHCSLLAEDAVKAAIKDYNMKQATKKDKLSSSNE
>Mature_136_residues
SYSESLLEHYKNPKNVGTLPKEDYNVGTGLVGAPSCGDVMKLQIKVDDNGKIIDAKFKTFGCGAAIAASSLATELIKGKT
IDEAHQLKNTVLAKELSLPPVKIHCSLLAEDAVKAAIKDYNMKQATKKDKLSSSNE

Specific function: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins (Potential) [H]

COG id: COG0822

COG function: function code C; NifU homolog involved in Fe-S cluster formation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nifU family [H]

Homologues:

Organism=Homo sapiens, GI56699456, Length=127, Percent_Identity=68.503937007874, Blast_Score=193, Evalue=4e-50,
Organism=Homo sapiens, GI24307953, Length=129, Percent_Identity=67.4418604651163, Blast_Score=191, Evalue=2e-49,
Organism=Escherichia coli, GI1788878, Length=128, Percent_Identity=65.625, Blast_Score=187, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17543474, Length=126, Percent_Identity=69.8412698412698, Blast_Score=192, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6325122, Length=126, Percent_Identity=66.6666666666667, Blast_Score=177, Evalue=6e-46,
Organism=Saccharomyces cerevisiae, GI6324800, Length=124, Percent_Identity=63.7096774193548, Blast_Score=171, Evalue=4e-44,
Organism=Drosophila melanogaster, GI21355597, Length=126, Percent_Identity=73.8095238095238, Blast_Score=204, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011339
- InterPro:   IPR002871 [H]

Pfam domain/function: PF01592 NifU_N [H]

EC number: NA

Molecular weight: Translated: 14709; Mature: 14578

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYSESLLEHYKNPKNVGTLPKEDYNVGTGLVGAPSCGDVMKLQIKVDDNGKIIDAKFKT
CCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEECCC
FGCGAAIAASSLATELIKGKTIDEAHQLKNTVLAKELSLPPVKIHCSLLAEDAVKAAIKD
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHH
YNMKQATKKDKLSSSNE
CCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SYSESLLEHYKNPKNVGTLPKEDYNVGTGLVGAPSCGDVMKLQIKVDDNGKIIDAKFKT
CHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEECCC
FGCGAAIAASSLATELIKGKTIDEAHQLKNTVLAKELSLPPVKIHCSLLAEDAVKAAIKD
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHH
YNMKQATKKDKLSSSNE
CCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]