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The map label for this gene is glpX [H]

Identifier: 88607690

GI number: 88607690

Start: 219584

End: 220519

Strand: Direct

Name: glpX [H]

Synonym: APH_0222

Alternate gene names: 88607690

Gene position: 219584-220519 (Clockwise)

Preceding gene: 88606908

Following gene: 88607005

Centisome position: 14.92

GC content: 45.51

Gene sequence:

>936_bases
ATGCTAATAGAAGATCTGTGTTTTCAGTTTCTAAAAGTAACGGAACTTGCAGCTGTTGAGGCGTACAAGTTTGCAGGAAA
GTCTGACGAAAAGGGAGCAGACCGAGCGGCGGTGGATGCAATGCGTTCTACTCTGAACACTATGGCTATAGATGGTGAAA
TAGTGATAGGAGAGGGAGAAAGAGATAATGCTCCTATGCTATATATAGGGGAGAGAGTTGGTAAAGGTGGGCCTGCTCTT
GACATAGCAGTTGATCCTCTAGAAGGTACGACCACGTGCGCTCTGCATAAGGATGGGGCAATGTCAGTAATTGCCGTGGC
CAAGAAGGGTAGTCTGCTAAAAGCTCCAGATGTGTACATGGACAGAATAGCTGTAGGGCCAGGCTTGCCAGCAGGTATTG
TGAGTATGGACAATGATCTGAAGACTAATTTGCAAAATTTGTCTGTGGCTAAGAAACGAGCAATGACAGATCTAGTAGCC
GTAGTATTAAAGAGAGATAGACACCTTTCTTTGATCAGTGAGCTAAGATCGCTAGGTGTGAGAGTACGGTTAATTGACGA
CGGCGATATCGGTGCTGTTATATCTCTCATAAAAGGTGAGAATGATATCTGCTTGGGGGTAGGCGGCGCTACAGAAGGCG
TGCTTTCAGCTGTGGCATTGTCGGCTGTAGGAGGGCAGATCTGTGGTAGATTGGTATTAAATACCGCTGAGTTACGTGAT
AGGGCAGGCAAGTTAGGTATAAGTGACTACGACAGAGAATACACAGAGCGTGATATGGTAAGAGATAGAGCATTCATGAT
AGTCACAGGTGTTACGTGTAGCACTCTCATGAATGGCATTAGATATAATGGCCATAGTCAATTAGAAACGGATTCTATGC
TTTTCTTGCCAGAAGGGGTTATTACGCACGTGAGACGTACGCACGTAGGCATGTAG

Upstream 100 bases:

>100_bases
CCGCTATCCGCACATTAGTCTATTGATTACACAATAACTCGTGTATCATAATGGAGTATTACATTTTTGTGAATGACTAT
TTCGAGATAGCGAGGAATTA

Downstream 100 bases:

>100_bases
ATTTGGGAGTGTATAGCAGTAGGGTAAGTTTCTATGTGCTGTTCGGTTGCGCGGGGTCGTCAACTTCAACGCTTTTGTGC
TGTGGAGCATCTTAGTCAGG

Product: fructose 1,6-bisphosphatase II

Products: NA

Alternate protein names: FBPase class 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2 [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MLIEDLCFQFLKVTELAAVEAYKFAGKSDEKGADRAAVDAMRSTLNTMAIDGEIVIGEGERDNAPMLYIGERVGKGGPAL
DIAVDPLEGTTTCALHKDGAMSVIAVAKKGSLLKAPDVYMDRIAVGPGLPAGIVSMDNDLKTNLQNLSVAKKRAMTDLVA
VVLKRDRHLSLISELRSLGVRVRLIDDGDIGAVISLIKGENDICLGVGGATEGVLSAVALSAVGGQICGRLVLNTAELRD
RAGKLGISDYDREYTERDMVRDRAFMIVTGVTCSTLMNGIRYNGHSQLETDSMLFLPEGVITHVRRTHVGM

Sequences:

>Translated_311_residues
MLIEDLCFQFLKVTELAAVEAYKFAGKSDEKGADRAAVDAMRSTLNTMAIDGEIVIGEGERDNAPMLYIGERVGKGGPAL
DIAVDPLEGTTTCALHKDGAMSVIAVAKKGSLLKAPDVYMDRIAVGPGLPAGIVSMDNDLKTNLQNLSVAKKRAMTDLVA
VVLKRDRHLSLISELRSLGVRVRLIDDGDIGAVISLIKGENDICLGVGGATEGVLSAVALSAVGGQICGRLVLNTAELRD
RAGKLGISDYDREYTERDMVRDRAFMIVTGVTCSTLMNGIRYNGHSQLETDSMLFLPEGVITHVRRTHVGM
>Mature_311_residues
MLIEDLCFQFLKVTELAAVEAYKFAGKSDEKGADRAAVDAMRSTLNTMAIDGEIVIGEGERDNAPMLYIGERVGKGGPAL
DIAVDPLEGTTTCALHKDGAMSVIAVAKKGSLLKAPDVYMDRIAVGPGLPAGIVSMDNDLKTNLQNLSVAKKRAMTDLVA
VVLKRDRHLSLISELRSLGVRVRLIDDGDIGAVISLIKGENDICLGVGGATEGVLSAVALSAVGGQICGRLVLNTAELRD
RAGKLGISDYDREYTERDMVRDRAFMIVTGVTCSTLMNGIRYNGHSQLETDSMLFLPEGVITHVRRTHVGM

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Can functionally substitute for the FBPase class 3 (Fbp) of B.subtilis [H]

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790360, Length=269, Percent_Identity=43.8661710037175, Blast_Score=204, Evalue=6e-54,
Organism=Escherichia coli, GI1789298, Length=307, Percent_Identity=38.7622149837134, Blast_Score=178, Evalue=5e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004464 [H]

Pfam domain/function: PF03320 FBPase_glpX [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 33247; Mature: 33247

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIEDLCFQFLKVTELAAVEAYKFAGKSDEKGADRAAVDAMRSTLNTMAIDGEIVIGEGE
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHEEECCEEEEECCC
RDNAPMLYIGERVGKGGPALDIAVDPLEGTTTCALHKDGAMSVIAVAKKGSLLKAPDVYM
CCCCCEEEEECCCCCCCCEEEEEECCCCCCEEEEEECCCCEEEEEEECCCCEECCCHHHH
DRIAVGPGLPAGIVSMDNDLKTNLQNLSVAKKRAMTDLVAVVLKRDRHLSLISELRSLGV
HHEECCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCE
RVRLIDDGDIGAVISLIKGENDICLGVGGATEGVLSAVALSAVGGQICGRLVLNTAELRD
EEEEEECCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAGKLGISDYDREYTERDMVRDRAFMIVTGVTCSTLMNGIRYNGHSQLETDSMLFLPEGV
HHCCCCCCHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHCCCCCCCCCCCCEEEECCHH
ITHVRRTHVGM
HHHHHHHHCCC
>Mature Secondary Structure
MLIEDLCFQFLKVTELAAVEAYKFAGKSDEKGADRAAVDAMRSTLNTMAIDGEIVIGEGE
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHEEECCEEEEECCC
RDNAPMLYIGERVGKGGPALDIAVDPLEGTTTCALHKDGAMSVIAVAKKGSLLKAPDVYM
CCCCCEEEEECCCCCCCCEEEEEECCCCCCEEEEEECCCCEEEEEEECCCCEECCCHHHH
DRIAVGPGLPAGIVSMDNDLKTNLQNLSVAKKRAMTDLVAVVLKRDRHLSLISELRSLGV
HHEECCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCE
RVRLIDDGDIGAVISLIKGENDICLGVGGATEGVLSAVALSAVGGQICGRLVLNTAELRD
EEEEEECCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAGKLGISDYDREYTERDMVRDRAFMIVTGVTCSTLMNGIRYNGHSQLETDSMLFLPEGV
HHCCCCCCHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHCCCCCCCCCCCCEEEECCHH
ITHVRRTHVGM
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8423140; 9353933; 9384377 [H]