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The map label for this gene is purQ [H]

Identifier: 88607005

GI number: 88607005

Start: 223222

End: 224004

Strand: Direct

Name: purQ [H]

Synonym: APH_0225

Alternate gene names: 88607005

Gene position: 223222-224004 (Clockwise)

Preceding gene: 88607690

Following gene: 88606706

Centisome position: 15.17

GC content: 43.68

Gene sequence:

>783_bases
ATGAACGTTATTGTATTATCAGGATATGGGCTGAACTGTGAGGAAGAGACGCTTTTTGCTTTCCAGGAGGCGGGTAGGTA
TCTAAACACTAACATCTCTGGTAAAATTGTGCATATCAAAGAGCTGTTATCAAATCCTAAGCAGCTTGCTTCGTTCAATA
CTATGGTAATACCAGGAGGGTTTTCCTACGGTGATGATACCGGTGCGGGAAATGCGTATGCGTTACGACTAATTCATGGA
CTGAATGAGCACATTCGTGACTTTATGGCACGTGATACTCTCCTGTTGGGTATTTGCAATGGGTGCCAAATACTACTCAG
GATGTTGTGTCCGAATGTTGCTTTGGTCAGTAATGACGTTGGCATGTACCAGTGTCGTTGGGTTACAGTAAAGGCAAGTA
ACAACTCTGTATGGTTGGACGGCATAGATAAGATGTATATTCCAGTGGCACATGGTGAGGGCAAGTTTTACGCTGCTGAG
GATGTGCTACAAAATCTAGAAACGCAGGGAGATATAGCGTTGCGTTATGTAAACTCTGATGGAGAATATGCGGAAGGAGA
GTTCCCTTATAACCCTAATGGATCAGCACGGGACATTGCTGCTATAACGTGCAACAGTGGGAGGGCGCTGATGATGATGC
CGCATCCCGAAAGGGCAATATTCTTTACTCAAAGATATGACTGGACCGATATTGTACATGGTCACCAGAATACAAAAGGG
GCTGTAGAGAAATATGCTGATGGATTTCAGATTTTTGTAAACGCTGTTAGATACTTCTCATAG

Upstream 100 bases:

>100_bases
ACAACCTACCGTTATTACTAAAATATACTCGATAGATGGTAAAAAGTAATATAAGTCATGTCAAATGATGCTAAAATTCA
TGAGTTTATTAGGTAGATGC

Downstream 100 bases:

>100_bases
CCGTGGTTTGACATGCGTTATGATCCTGCGATGGCTAGTATGGCATGTGATATCTACAGATGTGTGGTCTTTAGTATTAG
GTGATGTTCTAGAATTTGAA

Product: putative phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MNVIVLSGYGLNCEEETLFAFQEAGRYLNTNISGKIVHIKELLSNPKQLASFNTMVIPGGFSYGDDTGAGNAYALRLIHG
LNEHIRDFMARDTLLLGICNGCQILLRMLCPNVALVSNDVGMYQCRWVTVKASNNSVWLDGIDKMYIPVAHGEGKFYAAE
DVLQNLETQGDIALRYVNSDGEYAEGEFPYNPNGSARDIAAITCNSGRALMMMPHPERAIFFTQRYDWTDIVHGHQNTKG
AVEKYADGFQIFVNAVRYFS

Sequences:

>Translated_260_residues
MNVIVLSGYGLNCEEETLFAFQEAGRYLNTNISGKIVHIKELLSNPKQLASFNTMVIPGGFSYGDDTGAGNAYALRLIHG
LNEHIRDFMARDTLLLGICNGCQILLRMLCPNVALVSNDVGMYQCRWVTVKASNNSVWLDGIDKMYIPVAHGEGKFYAAE
DVLQNLETQGDIALRYVNSDGEYAEGEFPYNPNGSARDIAAITCNSGRALMMMPHPERAIFFTQRYDWTDIVHGHQNTKG
AVEKYADGFQIFVNAVRYFS
>Mature_260_residues
MNVIVLSGYGLNCEEETLFAFQEAGRYLNTNISGKIVHIKELLSNPKQLASFNTMVIPGGFSYGDDTGAGNAYALRLIHG
LNEHIRDFMARDTLLLGICNGCQILLRMLCPNVALVSNDVGMYQCRWVTVKASNNSVWLDGIDKMYIPVAHGEGKFYAAE
DVLQNLETQGDIALRYVNSDGEYAEGEFPYNPNGSARDIAAITCNSGRALMMMPHPERAIFFTQRYDWTDIVHGHQNTKG
AVEKYADGFQIFVNAVRYFS

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=281, Percent_Identity=30.2491103202847, Blast_Score=101, Evalue=7e-22,
Organism=Escherichia coli, GI48994899, Length=242, Percent_Identity=38.4297520661157, Blast_Score=136, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17553022, Length=204, Percent_Identity=30.3921568627451, Blast_Score=97, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6321498, Length=238, Percent_Identity=36.1344537815126, Blast_Score=118, Evalue=8e-28,
Organism=Drosophila melanogaster, GI24582111, Length=246, Percent_Identity=33.3333333333333, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24582109, Length=246, Percent_Identity=33.3333333333333, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI17137292, Length=246, Percent_Identity=33.3333333333333, Blast_Score=129, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 28943; Mature: 28943

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVIVLSGYGLNCEEETLFAFQEAGRYLNTNISGKIVHIKELLSNPKQLASFNTMVIPGG
CEEEEEECCCCCCCHHHHHHHHHCCCEECCCCCEEEEEHHHHHCCHHHHHCCCEEEECCC
FSYGDDTGAGNAYALRLIHGLNEHIRDFMARDTLLLGICNGCQILLRMLCPNVALVSNDV
CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCEEEEEEHHHHHHHHHHHCCCEEEEECCC
GMYQCRWVTVKASNNSVWLDGIDKMYIPVAHGEGKFYAAEDVLQNLETQGDIALRYVNSD
CEEEEEEEEEEECCCEEEEECCCEEEEEEECCCCCEEEHHHHHHHCCCCCCEEEEEECCC
GEYAEGEFPYNPNGSARDIAAITCNSGRALMMMPHPERAIFFTQRYDWTDIVHGHQNTKG
CCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCCEEEEEECCCHHHHHCCCCCCHH
AVEKYADGFQIFVNAVRYFS
HHHHHHCHHHHHHHHHHHCC
>Mature Secondary Structure
MNVIVLSGYGLNCEEETLFAFQEAGRYLNTNISGKIVHIKELLSNPKQLASFNTMVIPGG
CEEEEEECCCCCCCHHHHHHHHHCCCEECCCCCEEEEEHHHHHCCHHHHHCCCEEEECCC
FSYGDDTGAGNAYALRLIHGLNEHIRDFMARDTLLLGICNGCQILLRMLCPNVALVSNDV
CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCEEEEEEHHHHHHHHHHHCCCEEEEECCC
GMYQCRWVTVKASNNSVWLDGIDKMYIPVAHGEGKFYAAEDVLQNLETQGDIALRYVNSD
CEEEEEEEEEEECCCEEEEECCCEEEEEEECCCCCEEEHHHHHHHCCCCCCEEEEEECCC
GEYAEGEFPYNPNGSARDIAAITCNSGRALMMMPHPERAIFFTQRYDWTDIVHGHQNTKG
CCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCCEEEEEECCCHHHHHCCCCCCHH
AVEKYADGFQIFVNAVRYFS
HHHHHHCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA