Click here to switch to the map view.

The map label for this gene is ntrY [H]

Identifier: 88607475

GI number: 88607475

Start: 139419

End: 141521

Strand: Direct

Name: ntrY [H]

Synonym: APH_0136

Alternate gene names: 88607475

Gene position: 139419-141521 (Clockwise)

Preceding gene: 88606701

Following gene: 88607542

Centisome position: 9.48

GC content: 41.99

Gene sequence:

>2103_bases
ATGGTATGGCTAGGCGCTAGAAAGAGGCGTCGTCTATGGGGTATTCTGGTTGACTTATTATCGTCCGGATTTTGCTCTGT
GGGATTGGCGTCTCTTGATTTTTCCCTCATTTTGTCGTTGTTAGATGTTCAGGAATCATGGAACATTGCGACTGAGGAGA
ATATACAATTGCTCCTATGGGTGCTGTTAGTGTTCTTGCTTTGCATAGCTTCGTTGTCTTGTTGGACGATGCATGCTTGG
ATAAAGTGCAATAGGGGAGAGCTAGGTTTTAAGCTGCAAGCCAGGGCTGTTATAGTGTTCACCCTGGTGGGGATGATCCC
GGCTGTAGTTGCTTCGGGGTTTGCATATCTTTTCTTTGATTATGGTGTGAGGGCCTGGTATTACAATAACATACGGCCTG
CGTTCACTCGGTATATTGAAGAGACTTTGAAGTGTGCAGACGAATGCAGTACTGCTGTCATGGTTTCGGATGCTGTGCAT
CTTGCCAACTATTTGGGTACAGATTCTGCGCAGTGGACGTCAGAAAAGATCTCATTAGGGGCTGAGCTATTTAGTTTTTC
GGAAATTCTACTTATCAGTCATAGAGAGATTTTGGCTAGCGCAAACCCTAGTTCTACATCTTGGACTAATTACGTAACTG
AAGATGAGCTTTATGAAATTAATGACAAGCCAGTAGTTTTTTCTAAAGGACAGAAGGACTATACTGTGCAATTGTTAGAT
TCTTTGTCTGGTATTTATCTTATAGCAGTTCGGCCTCCAGACGACGCTTTGGAGCATAATATGCTGCGCTTTGAAGAGAT
GCATGAGCATCTAAATAATCTGCGAACGCAGATGTCTGCATTACAAATCCAATTTTCACTGGCATTTCTTTTGTTATTTT
TGGTTGTGTTGTTTGTGTCGGTGTGGTTAGGGGTAGGTTTTGCCAAAGGTATAGTGGGGCGTTTATCTGAGTTATTTGCA
GCCACTAAGCGGGTTCAAGATGGGGATTTTGATTGTAGGATAGAGTACAAAGGAAAAATTATGGGTGAAGAGATCGCTAC
GGTGATCAAGGCATTCAATCAAATGGTGGAACGGCTAAGTGAGCAACGTATGCAGTTAGAAAATGCATATAGAGAAATAA
ATGTTAGAAAAGTGTTCGTCGAAACTGTTTTGTCAGGAGTATCGTCGGGGGTTATGGCTTTATCCCCGTTAAAATCTGTA
ACTTTGATGAATGATAGGGCAATGGAGCTTTTGTCATGCTATGAGCTCAACAAACCAATAGAAGAAGTGTTGCCAGAAGT
TTTGGAGCTGGTAAACATGGTCAAATGTAAGGGTGATATCACTATTATTCGTAATCATAAGTTACTTACCTTATCGGTGA
ATATAGAACGGTTGAAGTCTCAGGGACTGATTATTACATTTGACGATATTTCTGGTTTGGTAGAAGCTCAAAGGAAGGCA
GCGTGGTCAGATGTAGCTAGGAGGATAGCTCACGAAATAAAAAATCCTATTACGCCCATTTACCTGGCAGCAGAGCGCCT
TGGGAGCAAGTATGCTGAGCAGATAGTATCAGGAAGAGAGACCTTTTTGCGGTACACAGATACCATAATTAAGCACGTAT
CAAATATTAGCTGTATAGTGGACGAGTTTGCACAATTCGCGCGAATGCCCAGCCCGACCTTTAAAATGTGTTACATTTCT
GTTATTATTAGGGACATAAGTTTTCTGGGACAGTTCGGTAAAGCCTTTGTTTCTTACGATTTGCACTTTCCTGAGGAAGA
GGTCCTTGTTTTTATAGATCAGGAACAGATTTCTCAAGTATTCGTGAACATATTTAAGAATGCTTGCGAGTCGATAAACG
CAAGTCCTAATGCTGATAGGGGGCGCATCGTTGTTACTGTAACAAAGGAAGAAAAGAGTGTTTTGGTTGAAGTGAGAGAT
AACGGTATAGGGTTTTCGGAGGATATTATGGGAAGGCTTACAGAACCCTATGTTACTACACGTGAAAAGGGTACTGGGTT
AGGGTTAGCGATAGTAGAGAAGATCCTGCAAGAGCATGGCGCATCTATAGGTTTCCGTAACTCAGAGGAAGGTGGTGTGG
TACGGATTACTTTTTTGAAATGA

Upstream 100 bases:

>100_bases
GAAGGTTAGGTACCAGTTGGATGAAAATAACGGAAAGGTTTCTGCTGTGAACCTAGAGGTGCTTTCGGAGTAACACTATG
TTTGGGCCTTGTCAGGATGT

Downstream 100 bases:

>100_bases
GAAAAATGTGTTTATTTGTTCAACAAATGATCTATCTAGGTTTTGTACGGAGTTATTACGTGATAACCCCGAAAGTGTGG
CAATAGACACGGAGTTTTTG

Product: nitrogen regulation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 700; Mature: 700

Protein sequence:

>700_residues
MVWLGARKRRRLWGILVDLLSSGFCSVGLASLDFSLILSLLDVQESWNIATEENIQLLLWVLLVFLLCIASLSCWTMHAW
IKCNRGELGFKLQARAVIVFTLVGMIPAVVASGFAYLFFDYGVRAWYYNNIRPAFTRYIEETLKCADECSTAVMVSDAVH
LANYLGTDSAQWTSEKISLGAELFSFSEILLISHREILASANPSSTSWTNYVTEDELYEINDKPVVFSKGQKDYTVQLLD
SLSGIYLIAVRPPDDALEHNMLRFEEMHEHLNNLRTQMSALQIQFSLAFLLLFLVVLFVSVWLGVGFAKGIVGRLSELFA
ATKRVQDGDFDCRIEYKGKIMGEEIATVIKAFNQMVERLSEQRMQLENAYREINVRKVFVETVLSGVSSGVMALSPLKSV
TLMNDRAMELLSCYELNKPIEEVLPEVLELVNMVKCKGDITIIRNHKLLTLSVNIERLKSQGLIITFDDISGLVEAQRKA
AWSDVARRIAHEIKNPITPIYLAAERLGSKYAEQIVSGRETFLRYTDTIIKHVSNISCIVDEFAQFARMPSPTFKMCYIS
VIIRDISFLGQFGKAFVSYDLHFPEEEVLVFIDQEQISQVFVNIFKNACESINASPNADRGRIVVTVTKEEKSVLVEVRD
NGIGFSEDIMGRLTEPYVTTREKGTGLGLAIVEKILQEHGASIGFRNSEEGGVVRITFLK

Sequences:

>Translated_700_residues
MVWLGARKRRRLWGILVDLLSSGFCSVGLASLDFSLILSLLDVQESWNIATEENIQLLLWVLLVFLLCIASLSCWTMHAW
IKCNRGELGFKLQARAVIVFTLVGMIPAVVASGFAYLFFDYGVRAWYYNNIRPAFTRYIEETLKCADECSTAVMVSDAVH
LANYLGTDSAQWTSEKISLGAELFSFSEILLISHREILASANPSSTSWTNYVTEDELYEINDKPVVFSKGQKDYTVQLLD
SLSGIYLIAVRPPDDALEHNMLRFEEMHEHLNNLRTQMSALQIQFSLAFLLLFLVVLFVSVWLGVGFAKGIVGRLSELFA
ATKRVQDGDFDCRIEYKGKIMGEEIATVIKAFNQMVERLSEQRMQLENAYREINVRKVFVETVLSGVSSGVMALSPLKSV
TLMNDRAMELLSCYELNKPIEEVLPEVLELVNMVKCKGDITIIRNHKLLTLSVNIERLKSQGLIITFDDISGLVEAQRKA
AWSDVARRIAHEIKNPITPIYLAAERLGSKYAEQIVSGRETFLRYTDTIIKHVSNISCIVDEFAQFARMPSPTFKMCYIS
VIIRDISFLGQFGKAFVSYDLHFPEEEVLVFIDQEQISQVFVNIFKNACESINASPNADRGRIVVTVTKEEKSVLVEVRD
NGIGFSEDIMGRLTEPYVTTREKGTGLGLAIVEKILQEHGASIGFRNSEEGGVVRITFLK
>Mature_700_residues
MVWLGARKRRRLWGILVDLLSSGFCSVGLASLDFSLILSLLDVQESWNIATEENIQLLLWVLLVFLLCIASLSCWTMHAW
IKCNRGELGFKLQARAVIVFTLVGMIPAVVASGFAYLFFDYGVRAWYYNNIRPAFTRYIEETLKCADECSTAVMVSDAVH
LANYLGTDSAQWTSEKISLGAELFSFSEILLISHREILASANPSSTSWTNYVTEDELYEINDKPVVFSKGQKDYTVQLLD
SLSGIYLIAVRPPDDALEHNMLRFEEMHEHLNNLRTQMSALQIQFSLAFLLLFLVVLFVSVWLGVGFAKGIVGRLSELFA
ATKRVQDGDFDCRIEYKGKIMGEEIATVIKAFNQMVERLSEQRMQLENAYREINVRKVFVETVLSGVSSGVMALSPLKSV
TLMNDRAMELLSCYELNKPIEEVLPEVLELVNMVKCKGDITIIRNHKLLTLSVNIERLKSQGLIITFDDISGLVEAQRKA
AWSDVARRIAHEIKNPITPIYLAAERLGSKYAEQIVSGRETFLRYTDTIIKHVSNISCIVDEFAQFARMPSPTFKMCYIS
VIIRDISFLGQFGKAFVSYDLHFPEEEVLVFIDQEQISQVFVNIFKNACESINASPNADRGRIVVTVTKEEKSVLVEVRD
NGIGFSEDIMGRLTEPYVTTREKGTGLGLAIVEKILQEHGASIGFRNSEEGGVVRITFLK

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=375, Percent_Identity=22.1333333333333, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI1790436, Length=230, Percent_Identity=28.695652173913, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1790300, Length=297, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1790861, Length=213, Percent_Identity=24.8826291079812, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 78887; Mature: 78887

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVWLGARKRRRLWGILVDLLSSGFCSVGLASLDFSLILSLLDVQESWNIATEENIQLLLW
CCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
VLLVFLLCIASLSCWTMHAWIKCNRGELGFKLQARAVIVFTLVGMIPAVVASGFAYLFFD
HHHHHHHHHHHHHHHEEEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHH
YGVRAWYYNNIRPAFTRYIEETLKCADECSTAVMVSDAVHLANYLGTDSAQWTSEKISLG
HCCCEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
AELFSFSEILLISHREILASANPSSTSWTNYVTEDELYEINDKPVVFSKGQKDYTVQLLD
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCEEEECCCCCHHHHHHH
SLSGIYLIAVRPPDDALEHNMLRFEEMHEHLNNLRTQMSALQIQFSLAFLLLFLVVLFVS
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VWLGVGFAKGIVGRLSELFAATKRVQDGDFDCRIEYKGKIMGEEIATVIKAFNQMVERLS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
EQRMQLENAYREINVRKVFVETVLSGVSSGVMALSPLKSVTLMNDRAMELLSCYELNKPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHCCHHHHHHHHHHHCCCCH
EEVLPEVLELVNMVKCKGDITIIRNHKLLTLSVNIERLKSQGLIITFDDISGLVEAQRKA
HHHHHHHHHHHHHHHCCCCEEEEECCEEEEEEEEHHHHHCCCEEEEEHHHHHHHHHHHHH
AWSDVARRIAHEIKNPITPIYLAAERLGSKYAEQIVSGRETFLRYTDTIIKHVSNISCIV
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
DEFAQFARMPSPTFKMCYISVIIRDISFLGQFGKAFVSYDLHFPEEEVLVFIDQEQISQV
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEEECHHHHHHH
FVNIFKNACESINASPNADRGRIVVTVTKEEKSVLVEVRDNGIGFSEDIMGRLTEPYVTT
HHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHCCCCCEEC
REKGTGLGLAIVEKILQEHGASIGFRNSEEGGVVRITFLK
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEC
>Mature Secondary Structure
MVWLGARKRRRLWGILVDLLSSGFCSVGLASLDFSLILSLLDVQESWNIATEENIQLLLW
CCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
VLLVFLLCIASLSCWTMHAWIKCNRGELGFKLQARAVIVFTLVGMIPAVVASGFAYLFFD
HHHHHHHHHHHHHHHEEEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHH
YGVRAWYYNNIRPAFTRYIEETLKCADECSTAVMVSDAVHLANYLGTDSAQWTSEKISLG
HCCCEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
AELFSFSEILLISHREILASANPSSTSWTNYVTEDELYEINDKPVVFSKGQKDYTVQLLD
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCEEEECCCCCHHHHHHH
SLSGIYLIAVRPPDDALEHNMLRFEEMHEHLNNLRTQMSALQIQFSLAFLLLFLVVLFVS
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VWLGVGFAKGIVGRLSELFAATKRVQDGDFDCRIEYKGKIMGEEIATVIKAFNQMVERLS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
EQRMQLENAYREINVRKVFVETVLSGVSSGVMALSPLKSVTLMNDRAMELLSCYELNKPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHCCHHHHHHHHHHHCCCCH
EEVLPEVLELVNMVKCKGDITIIRNHKLLTLSVNIERLKSQGLIITFDDISGLVEAQRKA
HHHHHHHHHHHHHHHCCCCEEEEECCEEEEEEEEHHHHHCCCEEEEEHHHHHHHHHHHHH
AWSDVARRIAHEIKNPITPIYLAAERLGSKYAEQIVSGRETFLRYTDTIIKHVSNISCIV
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
DEFAQFARMPSPTFKMCYISVIIRDISFLGQFGKAFVSYDLHFPEEEVLVFIDQEQISQV
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEEECHHHHHHH
FVNIFKNACESINASPNADRGRIVVTVTKEEKSVLVEVRDNGIGFSEDIMGRLTEPYVTT
HHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHCCCCCEEC
REKGTGLGLAIVEKILQEHGASIGFRNSEEGGVVRITFLK
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]