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The map label for this gene is ccmC [H]

Identifier: 88606928

GI number: 88606928

Start: 170425

End: 171132

Strand: Reverse

Name: ccmC [H]

Synonym: APH_0168

Alternate gene names: 88606928

Gene position: 171132-170425 (Counterclockwise)

Preceding gene: 88606756

Following gene: 88607371

Centisome position: 11.63

GC content: 44.49

Gene sequence:

>708_bases
ATGCATAGTCTTGCACGCTTCTTGCGGTCATCACTGCGGTATGTTGTATGCTTTTTCGTGCTTGTTTTATCAGTCGGTCT
GTATTGTTCTATATTTGCATCACCAGCTGACTACCGTCAGGGTGAGGTAGTGCGAATTATGTATTTACATGTGCCATCCG
CTTGGATATCCCTCGGGTCATATACAGCTATCGCTCTGCTGAGTTTAGGAACTTTGCTGAAGAAAGGAGATATTTTCCCC
ATGATAGCTCGTGCTATAGCTCCTGTAGGCGCGTGTTTTACTGCAGTATGTCTTGTTGCTGGATGTATTTGGGGAAAATA
CACCTGGGGCACTTGGTGGGTCTGGGATGCACGTCTAACATCTGTGCTGCTGTTGTTTTTCCTCTTCTTGGGGTATGCAT
CCCTGTGGAATGTATTTGAAGACCAGAACAGAGCTGCAAAAACCACGTCACTGTTTGCTCTCTTTAGTGCTGTAAACGTG
CCAATAGTAAAGTTTTCTGTTGATATCTGGGCAACATTGCATCAAACCTCTAGTATCTTGAGGAAGGGCGGCATTGCCAT
AGATTCTTCTATGCTGATCCCTCTTCTGACTATGTTTGTAGCTCTATCGCTGCTGTTTGTCATTCTGACGTCGCTGCGCT
TTTATACGCTGTTGAATAATAGGCAGACGTCAAGTAGTCTATACCCTTTTTACCATGAAACAACATGA

Upstream 100 bases:

>100_bases
TATCCGGGCGATATGCACTATGCATGGGTAAGAATCTTGGTATTGTCCTTTATGTGTAACTATGTTACCATTCCATAATG
CATATAGCTTGTGAATAGGA

Downstream 100 bases:

>100_bases
TCGGAACTCTCTCAGGTATTATAGAAGAAGTACAGGATACTAGCATCATACTCGCGGTGGGTGGCGTCGGCTACATAGTA
CATGTCTCCTATAGAACGCT

Product: heme exporter protein CcmC

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycZ [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MHSLARFLRSSLRYVVCFFVLVLSVGLYCSIFASPADYRQGEVVRIMYLHVPSAWISLGSYTAIALLSLGTLLKKGDIFP
MIARAIAPVGACFTAVCLVAGCIWGKYTWGTWWVWDARLTSVLLLFFLFLGYASLWNVFEDQNRAAKTTSLFALFSAVNV
PIVKFSVDIWATLHQTSSILRKGGIAIDSSMLIPLLTMFVALSLLFVILTSLRFYTLLNNRQTSSSLYPFYHETT

Sequences:

>Translated_235_residues
MHSLARFLRSSLRYVVCFFVLVLSVGLYCSIFASPADYRQGEVVRIMYLHVPSAWISLGSYTAIALLSLGTLLKKGDIFP
MIARAIAPVGACFTAVCLVAGCIWGKYTWGTWWVWDARLTSVLLLFFLFLGYASLWNVFEDQNRAAKTTSLFALFSAVNV
PIVKFSVDIWATLHQTSSILRKGGIAIDSSMLIPLLTMFVALSLLFVILTSLRFYTLLNNRQTSSSLYPFYHETT
>Mature_235_residues
MHSLARFLRSSLRYVVCFFVLVLSVGLYCSIFASPADYRQGEVVRIMYLHVPSAWISLGSYTAIALLSLGTLLKKGDIFP
MIARAIAPVGACFTAVCLVAGCIWGKYTWGTWWVWDARLTSVLLLFFLFLGYASLWNVFEDQNRAAKTTSLFALFSAVNV
PIVKFSVDIWATLHQTSSILRKGGIAIDSSMLIPLLTMFVALSLLFVILTSLRFYTLLNNRQTSSSLYPFYHETT

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmC/CycZ/HelC family [H]

Homologues:

Organism=Escherichia coli, GI1788527, Length=199, Percent_Identity=42.2110552763819, Blast_Score=158, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003557 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 26328; Mature: 26328

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSLARFLRSSLRYVVCFFVLVLSVGLYCSIFASPADYRQGEVVRIMYLHVPSAWISLGS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCHHHHHHHH
YTAIALLSLGTLLKKGDIFPMIARAIAPVGACFTAVCLVAGCIWGKYTWGTWWVWDARLT
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHH
SVLLLFFLFLGYASLWNVFEDQNRAAKTTSLFALFSAVNVPIVKFSVDIWATLHQTSSIL
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHH
RKGGIAIDSSMLIPLLTMFVALSLLFVILTSLRFYTLLNNRQTSSSLYPFYHETT
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MHSLARFLRSSLRYVVCFFVLVLSVGLYCSIFASPADYRQGEVVRIMYLHVPSAWISLGS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCHHHHHHHH
YTAIALLSLGTLLKKGDIFPMIARAIAPVGACFTAVCLVAGCIWGKYTWGTWWVWDARLT
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHH
SVLLLFFLFLGYASLWNVFEDQNRAAKTTSLFALFSAVNVPIVKFSVDIWATLHQTSSIL
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHH
RKGGIAIDSSMLIPLLTMFVALSLLFVILTSLRFYTLLNNRQTSSSLYPFYHETT
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]