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The map label for this gene is glmS [H]

Identifier: 87200428

GI number: 87200428

Start: 2589143

End: 2590183

Strand: Reverse

Name: glmS [H]

Synonym: Saro_2415

Alternate gene names: 87200428

Gene position: 2590183-2589143 (Counterclockwise)

Preceding gene: 87200429

Following gene: 87200427

Centisome position: 72.73

GC content: 67.05

Gene sequence:

>1041_bases
ATGACGAGTGTTGAGCTGCATGCCGAGCAATCGGCGATGCGGCGCGAAGCAGCGGAAGCCGGCACTGCCGTCACCCGTTT
CCTGGCGCACAACGAAAAGAACCTGAAGGCCCTCGCCGAACGTCTGCGCGCATATCCGCCCAATGTGGTGGTCACCTGCG
CACGCGGCTCTTCGGACCATGCGGCGACGTTCGGCAAGTACCTTGTCGAAACGCGTCTCGGCATTCCCGTGTCTTCCGCC
GCGCCCTCTGTGGCTTCGGTCTTCGCGTCCGACGTGCGCCGCACCGGCTCGGTGCTCGTCGCGATCTCGCAATCCGGACG
CAGCCCCGATCTTCTTGCCACGGTGGAAAGCCACCGCGCGGCAGGCGCCTATGTGGTGGCCCTGGTCAACCAGCCGGATT
CCCCGCTCGAAAAGCTTGCCGACTGCTTCCTGCCGCTCTGCGCCGGCCCGGAACTGTCGGTAGCGGCGACGAAATCCTTC
GTCGTCTCGCTCGCGGCCCTTGCAGCCATCGTCGCGTGGTGGAGCGAGGACGAGGCGCTGAAGGATGCGCTTCACGGCCT
GCCCGCGCTGCTCGACCAGGCATATGCCCGCGATTGGACCGCTTTGGTCGATGCACTCGCGCCGGCCAATAATCTCCTCG
TCGTCGGGCGCGGCTATGGCCTCTCGGTCGCGCAGGAAGCGGCGCTCAAGCTCAAGGAAACCTGCGGCCTCCACGCCGAG
GCCTTCAGCAGCGCCGAAGTCCGCCATGGCCCCATGGCCATCGTTGGGGAAGGCTTTCCGATCCTCGCCCTCGCCACGTC
CGACGCTTCGGGCGATGACGTGCGCGCCGTCGCGGGCGAGTTCTCCGGTCGTGGCGCCCGGGTCCTTCTCGCAGACTGCT
CGCAATCCGCCGGCACGCTTCCGGCAGTCCCGGCGCACCCCGTGATCGAGCCGATCCTGCTGGTCCAGTCGTTCTATTCG
GCGGTCGAAACCCTGGCCCGCGCCCGGGGGATGGAGCCCGACAATCCCCCGTTCCTGCGAAAGGTGACAGAGACGCTATG
A

Upstream 100 bases:

>100_bases
AGGCCGTGGAGTTTACCCAATCGTACTATCGCGGCGACGCTTACGACCTCGTCGCAGAGTTGAACGCCAGCTAGAGGCGC
GGCGTGCACAAGGAGGGCTG

Downstream 100 bases:

>100_bases
CTGTCCTCGCCTTCCGCAACGGGCGCATTCTCCTGCCCGGCGGCATTGCCGAAAGTGCCCGGATCGAGATCGGCAACGAC
CGTATCGATGCGGTCCTCTC

Product: glutamine-fructose-6-phosphate transaminase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MTSVELHAEQSAMRREAAEAGTAVTRFLAHNEKNLKALAERLRAYPPNVVVTCARGSSDHAATFGKYLVETRLGIPVSSA
APSVASVFASDVRRTGSVLVAISQSGRSPDLLATVESHRAAGAYVVALVNQPDSPLEKLADCFLPLCAGPELSVAATKSF
VVSLAALAAIVAWWSEDEALKDALHGLPALLDQAYARDWTALVDALAPANNLLVVGRGYGLSVAQEAALKLKETCGLHAE
AFSSAEVRHGPMAIVGEGFPILALATSDASGDDVRAVAGEFSGRGARVLLADCSQSAGTLPAVPAHPVIEPILLVQSFYS
AVETLARARGMEPDNPPFLRKVTETL

Sequences:

>Translated_346_residues
MTSVELHAEQSAMRREAAEAGTAVTRFLAHNEKNLKALAERLRAYPPNVVVTCARGSSDHAATFGKYLVETRLGIPVSSA
APSVASVFASDVRRTGSVLVAISQSGRSPDLLATVESHRAAGAYVVALVNQPDSPLEKLADCFLPLCAGPELSVAATKSF
VVSLAALAAIVAWWSEDEALKDALHGLPALLDQAYARDWTALVDALAPANNLLVVGRGYGLSVAQEAALKLKETCGLHAE
AFSSAEVRHGPMAIVGEGFPILALATSDASGDDVRAVAGEFSGRGARVLLADCSQSAGTLPAVPAHPVIEPILLVQSFYS
AVETLARARGMEPDNPPFLRKVTETL
>Mature_345_residues
TSVELHAEQSAMRREAAEAGTAVTRFLAHNEKNLKALAERLRAYPPNVVVTCARGSSDHAATFGKYLVETRLGIPVSSAA
PSVASVFASDVRRTGSVLVAISQSGRSPDLLATVESHRAAGAYVVALVNQPDSPLEKLADCFLPLCAGPELSVAATKSFV
VSLAALAAIVAWWSEDEALKDALHGLPALLDQAYARDWTALVDALAPANNLLVVGRGYGLSVAQEAALKLKETCGLHAEA
FSSAEVRHGPMAIVGEGFPILALATSDASGDDVRAVAGEFSGRGARVLLADCSQSAGTLPAVPAHPVIEPILLVQSFYSA
VETLARARGMEPDNPPFLRKVTETL

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG2222

COG function: function code M; Predicted phosphosugar isomerases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=331, Percent_Identity=27.190332326284, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI205277386, Length=237, Percent_Identity=27.8481012658228, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1790167, Length=357, Percent_Identity=29.4117647058824, Blast_Score=119, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17532899, Length=280, Percent_Identity=27.5, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17532897, Length=280, Percent_Identity=27.5, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17539970, Length=274, Percent_Identity=28.1021897810219, Blast_Score=102, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6322745, Length=258, Percent_Identity=30.2325581395349, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6323731, Length=236, Percent_Identity=26.271186440678, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21357745, Length=269, Percent_Identity=26.0223048327138, Blast_Score=93, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 36183; Mature: 36052

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSVELHAEQSAMRREAAEAGTAVTRFLAHNEKNLKALAERLRAYPPNVVVTCARGSSDH
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCCCCCH
AATFGKYLVETRLGIPVSSAAPSVASVFASDVRRTGSVLVAISQSGRSPDLLATVESHRA
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEHHHCCC
AGAYVVALVNQPDSPLEKLADCFLPLCAGPELSVAATKSFVVSLAALAAIVAWWSEDEAL
CCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHH
KDALHGLPALLDQAYARDWTALVDALAPANNLLVVGRGYGLSVAQEAALKLKETCGLHAE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCHH
AFSSAEVRHGPMAIVGEGFPILALATSDASGDDVRAVAGEFSGRGARVLLADCSQSAGTL
HHCCCCCCCCCEEEEECCCEEEEEEECCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCC
PAVPAHPVIEPILLVQSFYSAVETLARARGMEPDNPPFLRKVTETL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
TSVELHAEQSAMRREAAEAGTAVTRFLAHNEKNLKALAERLRAYPPNVVVTCARGSSDH
CCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCCCCCH
AATFGKYLVETRLGIPVSSAAPSVASVFASDVRRTGSVLVAISQSGRSPDLLATVESHRA
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEHHHCCC
AGAYVVALVNQPDSPLEKLADCFLPLCAGPELSVAATKSFVVSLAALAAIVAWWSEDEAL
CCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHH
KDALHGLPALLDQAYARDWTALVDALAPANNLLVVGRGYGLSVAQEAALKLKETCGLHAE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCHH
AFSSAEVRHGPMAIVGEGFPILALATSDASGDDVRAVAGEFSGRGARVLLADCSQSAGTL
HHCCCCCCCCCEEEEECCCEEEEEEECCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCC
PAVPAHPVIEPILLVQSFYSAVETLARARGMEPDNPPFLRKVTETL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA