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The map label for this gene is nagA [H]

Identifier: 87200427

GI number: 87200427

Start: 2588004

End: 2589146

Strand: Reverse

Name: nagA [H]

Synonym: Saro_2414

Alternate gene names: 87200427

Gene position: 2589146-2588004 (Counterclockwise)

Preceding gene: 87200428

Following gene: 87200426

Centisome position: 72.7

GC content: 69.03

Gene sequence:

>1143_bases
ATGACTGTCCTCGCCTTCCGCAACGGGCGCATTCTCCTGCCCGGCGGCATTGCCGAAAGTGCCCGGATCGAGATCGGCAA
CGACCGTATCGATGCGGTCCTCTCGGGCGACGAGGCTGGCACAGGCCTCGGCCCATCCGTCGACCTCGGCGGTGGTTGGC
TCGTCCCGGGCTTCGTCGACACCCAGGTCAACGGCGGCGGCGGCGTGCTGTTCAACGACAGCCCGGACGTCGCCTCGCTT
GCCCGCATCAGCGCGGCCCATGCCCGCTTCGGCACGACCGCGCTCCTGCCCACCCTGATCAGCGCCCCGCGCGATACCAT
CGCACGCGCGCTCGATGCGGTGGACGAGGCAATCGCGTCCGGCGTTCCGGGCGTGATCGGCATCCATGTCGAAGGGCCGT
TCCTCAACGAGGCGCGGCGCGGCATCCACGATGCGGGGCAGTTCCGCCCGCTCGAGGACGAACTGATCGCGCTGCTCACC
CGCCCGCGCAAGGGCAAGGTCATGGTAACGCTCGCGCCTGAGTGCAACGCACCCGATGCGGTGCGCGCGCTGGTCGAGGC
GGGCGTGATCGTCAGCATCGGCCACAGCAACGCCAGCTACGAGGATGTGCGCCTTGCCATCGCCAATGGCGTGCGCGGCG
TCACCCACCTGTTCAACGCGATGTCGCCGTTCCACCACCGCCACCCCGGCGTCGTCGGCGCCGTGCTCGAGGACCGCAGC
CTGTGGTGCGGTCTCATCGTCGACGGTGCCCACGCCCATCCGGCGGCGATCCGCGTGGCCCTGGCCGCGCGTCCGGCGGA
CCGTTTCATGCTGGTCACCGATGCGATGCCGACCGTGGGAAGCGAGCGCAAGCGGTTCGTCCTGAATGGCGAGGAGATCA
CCGTGCGCGACGGCGTCTGCGTGAATGCCGAAGGAACGCTAGCCGGGTCGGACCTCGACATGGCCACCGCAATCCGCAAC
TCGGTCGAACTCGGCATGGCGCCGCACGTCGCTTTCGCGATGGCAACGCACAACCCCGCCGAATTTCTTGGGCTTGAATC
CAGCCGCGGCGCGATCGCACGCGGGCACCATGCCGATCTCGTCTGGCTCGATGCGGATTTCCGCACCCAGGCCACCTGGA
TCGGCGGGCAGCGGGTACGCTGA

Upstream 100 bases:

>100_bases
TGCTGGTCCAGTCGTTCTATTCGGCGGTCGAAACCCTGGCCCGCGCCCGGGGGATGGAGCCCGACAATCCCCCGTTCCTG
CGAAAGGTGACAGAGACGCT

Downstream 100 bases:

>100_bases
CGCAGCTTGCCGCCCCGTCGCGCCGCGTGGCAGCCGGGGATGGAGGGAAGAAATGATGGGGTCGATTGTTCTCTCTGCGC
CGATTGCAGGTTGGGTCTCC

Product: N-acetylglucosamine 6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MTVLAFRNGRILLPGGIAESARIEIGNDRIDAVLSGDEAGTGLGPSVDLGGGWLVPGFVDTQVNGGGGVLFNDSPDVASL
ARISAAHARFGTTALLPTLISAPRDTIARALDAVDEAIASGVPGVIGIHVEGPFLNEARRGIHDAGQFRPLEDELIALLT
RPRKGKVMVTLAPECNAPDAVRALVEAGVIVSIGHSNASYEDVRLAIANGVRGVTHLFNAMSPFHHRHPGVVGAVLEDRS
LWCGLIVDGAHAHPAAIRVALAARPADRFMLVTDAMPTVGSERKRFVLNGEEITVRDGVCVNAEGTLAGSDLDMATAIRN
SVELGMAPHVAFAMATHNPAEFLGLESSRGAIARGHHADLVWLDADFRTQATWIGGQRVR

Sequences:

>Translated_380_residues
MTVLAFRNGRILLPGGIAESARIEIGNDRIDAVLSGDEAGTGLGPSVDLGGGWLVPGFVDTQVNGGGGVLFNDSPDVASL
ARISAAHARFGTTALLPTLISAPRDTIARALDAVDEAIASGVPGVIGIHVEGPFLNEARRGIHDAGQFRPLEDELIALLT
RPRKGKVMVTLAPECNAPDAVRALVEAGVIVSIGHSNASYEDVRLAIANGVRGVTHLFNAMSPFHHRHPGVVGAVLEDRS
LWCGLIVDGAHAHPAAIRVALAARPADRFMLVTDAMPTVGSERKRFVLNGEEITVRDGVCVNAEGTLAGSDLDMATAIRN
SVELGMAPHVAFAMATHNPAEFLGLESSRGAIARGHHADLVWLDADFRTQATWIGGQRVR
>Mature_379_residues
TVLAFRNGRILLPGGIAESARIEIGNDRIDAVLSGDEAGTGLGPSVDLGGGWLVPGFVDTQVNGGGGVLFNDSPDVASLA
RISAAHARFGTTALLPTLISAPRDTIARALDAVDEAIASGVPGVIGIHVEGPFLNEARRGIHDAGQFRPLEDELIALLTR
PRKGKVMVTLAPECNAPDAVRALVEAGVIVSIGHSNASYEDVRLAIANGVRGVTHLFNAMSPFHHRHPGVVGAVLEDRSL
WCGLIVDGAHAHPAAIRVALAARPADRFMLVTDAMPTVGSERKRFVLNGEEITVRDGVCVNAEGTLAGSDLDMATAIRNS
VELGMAPHVAFAMATHNPAEFLGLESSRGAIARGHHADLVWLDADFRTQATWIGGQRVR

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=427, Percent_Identity=34.6604215456674, Blast_Score=195, Evalue=7e-50,
Organism=Homo sapiens, GI224922791, Length=424, Percent_Identity=34.6698113207547, Blast_Score=191, Evalue=7e-49,
Organism=Escherichia coli, GI1786892, Length=384, Percent_Identity=34.6354166666667, Blast_Score=219, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI17553768, Length=398, Percent_Identity=32.9145728643216, Blast_Score=175, Evalue=3e-44,
Organism=Drosophila melanogaster, GI19920392, Length=345, Percent_Identity=35.0724637681159, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI281361140, Length=357, Percent_Identity=34.453781512605, Blast_Score=186, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 39872; Mature: 39741

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLAFRNGRILLPGGIAESARIEIGNDRIDAVLSGDEAGTGLGPSVDLGGGWLVPGFVD
CEEEEEECCEEEECCCCCCCCEEEECCCEEEEEEECCCCCCCCCCCEECCCCEECCCEEE
TQVNGGGGVLFNDSPDVASLARISAAHARFGTTALLPTLISAPRDTIARALDAVDEAIAS
EEECCCCEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
GVPGVIGIHVEGPFLNEARRGIHDAGQFRPLEDELIALLTRPRKGKVMVTLAPECNAPDA
CCCCEEEEEECCCCHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCHH
VRALVEAGVIVSIGHSNASYEDVRLAIANGVRGVTHLFNAMSPFHHRHPGVVGAVLEDRS
HHHHHHCCEEEEECCCCCCHHHEEEEECCCCHHHHHHHHHHCCHHHCCCCEEEEEECCCC
LWCGLIVDGAHAHPAAIRVALAARPADRFMLVTDAMPTVGSERKRFVLNGEEITVRDGVC
EEEEEEEECCCCCCHHEEEEEEECCCCCEEEEECCCCCCCCCCCEEEECCCEEEEECCEE
VNAEGTLAGSDLDMATAIRNSVELGMAPHVAFAMATHNPAEFLGLESSRGAIARGHHADL
ECCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHEECCCCCCCEECCCCCEE
VWLDADFRTQATWIGGQRVR
EEEECCCCEEEEECCCCCCC
>Mature Secondary Structure 
TVLAFRNGRILLPGGIAESARIEIGNDRIDAVLSGDEAGTGLGPSVDLGGGWLVPGFVD
EEEEEECCEEEECCCCCCCCEEEECCCEEEEEEECCCCCCCCCCCEECCCCEECCCEEE
TQVNGGGGVLFNDSPDVASLARISAAHARFGTTALLPTLISAPRDTIARALDAVDEAIAS
EEECCCCEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
GVPGVIGIHVEGPFLNEARRGIHDAGQFRPLEDELIALLTRPRKGKVMVTLAPECNAPDA
CCCCEEEEEECCCCHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCHH
VRALVEAGVIVSIGHSNASYEDVRLAIANGVRGVTHLFNAMSPFHHRHPGVVGAVLEDRS
HHHHHHCCEEEEECCCCCCHHHEEEEECCCCHHHHHHHHHHCCHHHCCCCEEEEEECCCC
LWCGLIVDGAHAHPAAIRVALAARPADRFMLVTDAMPTVGSERKRFVLNGEEITVRDGVC
EEEEEEEECCCCCCHHEEEEEEECCCCCEEEEECCCCCCCCCCCEEEECCCEEEEECCEE
VNAEGTLAGSDLDMATAIRNSVELGMAPHVAFAMATHNPAEFLGLESSRGAIARGHHADL
ECCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHEECCCCCCCEECCCCCEE
VWLDADFRTQATWIGGQRVR
EEEECCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9301118; 10952301 [H]