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The map label for this gene is murG

Identifier: 87199155

GI number: 87199155

Start: 1178956

End: 1180122

Strand: Direct

Name: murG

Synonym: Saro_1133

Alternate gene names: 87199155

Gene position: 1178956-1180122 (Clockwise)

Preceding gene: 87199154

Following gene: 87199156

Centisome position: 33.1

GC content: 68.12

Gene sequence:

>1167_bases
ATGACGACAGTGTCCCGACACTATGTGCTGGCTGCCGGCGGCACCGGCGGACACCTGATCCCCGCTTTCGCGTTGGCCGT
GGAACTGGACCGTCGCGGCCATCACGTTGCGCTGGTCACGGACGAACGCGGCGCGAAGATTCCCGGAAAGCCCGATTTCC
TGCCTGCGCACGTGCTTCCCGCCGGGCGCCTCGGCAAGAACCCGGTCGCGCTGTTCAAGGGCCTGCGCGCGATCTGGCAA
GGCCGCGCCATGGCGCTGCGTCTGTTCGAAAGCTTCGAGCCTTCGTGCGTGATCGGCTTTGGCGGTTATCCGGCGCTTCC
CGCCCTGCTCGCGGCTCATGCGGCCAGGATCCCGACCGTCATCCACGAACAGAACGCGGTGCTGGGCCGCGTGAACCGCC
TGCTGGCCAAGCGGGTCGACGCCATCGCGACCGCCTATGGCGAGGTCGACCGGCTCGACCCGAAGCTGTGGGGCAAGGTT
CACCGCGTGGGCAATCCCGTGCGCCCGGATGTGCTGGCGCTACGCGGAGAACCGTTCCCCGAATTTACCGAGGACAGCCT
GTTCCGCGTCCTCGTGACCGGCGGGAGCCAGGGCGCATCGATCCTCTCGGAAGTCGTGCCCGATGGTCTCGCGATGTTGC
CCCCCGCCTTGCGCCACCGCCTGCAGGTGACCCAGCAGTGCCGGCCTGAGGACCTCGAGGTCGTTCGCGCCCGCTATGCC
GCGCACGAAATCCCCGCTGAACTTGGCACCTATTTCGAGGACATGCAGGCCCGGCTCGCGGGCACGCACCTGTTCATCGG
GCGGGCAGGGGCCTCGACCATCGCCGAACTGACCGCCGTCGGCCGTCCGGCGATCCTCGTTCCCCTGCCGATCGCGACCG
ACGATCATCAGGCCGCCAACACGCGCGAAGTCGTTGCCGCCGGGGGCGCCCGCGCGATCCGGCAGTCCGGCTTCACCCCC
AAGGAACTTGCAAAGCAGATCCAGGCCATGGCCCAGCACCCGCACACCCTTGCCAATGCCGCGCATGCCGCGTGGAACTG
CGGCCTGCCCAATGCCGTCAAGGACCTCGCTGACCTCGTCGAAAGCTTCGGCGCCAGCCCGATCATGGACGTGATCCGCC
TCGATTCCACCGTCTCGGCCGCATCCGGGCAGGAGCAACTGGCATGA

Upstream 100 bases:

>100_bases
CCATCGCGCTGCTCATGGGCGTCGGCTTCCTGCTCGCGATCACCCGCCGCAATCCCTATCTGTCGAGAGAGAAGTTCGCG
GTCACGGATCTGGTGCGCAA

Downstream 100 bases:

>100_bases
AGGGCGTCGGCACCGAGATCGGCACGATCCATTTCGTCGGCATCGGCGGCATCGGCATGTCAGGCATTGCCGAGGTCATG
CACAACATGGGCTATTCGGT

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MTTVSRHYVLAAGGTGGHLIPAFALAVELDRRGHHVALVTDERGAKIPGKPDFLPAHVLPAGRLGKNPVALFKGLRAIWQ
GRAMALRLFESFEPSCVIGFGGYPALPALLAAHAARIPTVIHEQNAVLGRVNRLLAKRVDAIATAYGEVDRLDPKLWGKV
HRVGNPVRPDVLALRGEPFPEFTEDSLFRVLVTGGSQGASILSEVVPDGLAMLPPALRHRLQVTQQCRPEDLEVVRARYA
AHEIPAELGTYFEDMQARLAGTHLFIGRAGASTIAELTAVGRPAILVPLPIATDDHQAANTREVVAAGGARAIRQSGFTP
KELAKQIQAMAQHPHTLANAAHAAWNCGLPNAVKDLADLVESFGASPIMDVIRLDSTVSAASGQEQLA

Sequences:

>Translated_388_residues
MTTVSRHYVLAAGGTGGHLIPAFALAVELDRRGHHVALVTDERGAKIPGKPDFLPAHVLPAGRLGKNPVALFKGLRAIWQ
GRAMALRLFESFEPSCVIGFGGYPALPALLAAHAARIPTVIHEQNAVLGRVNRLLAKRVDAIATAYGEVDRLDPKLWGKV
HRVGNPVRPDVLALRGEPFPEFTEDSLFRVLVTGGSQGASILSEVVPDGLAMLPPALRHRLQVTQQCRPEDLEVVRARYA
AHEIPAELGTYFEDMQARLAGTHLFIGRAGASTIAELTAVGRPAILVPLPIATDDHQAANTREVVAAGGARAIRQSGFTP
KELAKQIQAMAQHPHTLANAAHAAWNCGLPNAVKDLADLVESFGASPIMDVIRLDSTVSAASGQEQLA
>Mature_387_residues
TTVSRHYVLAAGGTGGHLIPAFALAVELDRRGHHVALVTDERGAKIPGKPDFLPAHVLPAGRLGKNPVALFKGLRAIWQG
RAMALRLFESFEPSCVIGFGGYPALPALLAAHAARIPTVIHEQNAVLGRVNRLLAKRVDAIATAYGEVDRLDPKLWGKVH
RVGNPVRPDVLALRGEPFPEFTEDSLFRVLVTGGSQGASILSEVVPDGLAMLPPALRHRLQVTQQCRPEDLEVVRARYAA
HEIPAELGTYFEDMQARLAGTHLFIGRAGASTIAELTAVGRPAILVPLPIATDDHQAANTREVVAAGGARAIRQSGFTPK
ELAKQIQAMAQHPHTLANAAHAAWNCGLPNAVKDLADLVESFGASPIMDVIRLDSTVSAASGQEQLA

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=372, Percent_Identity=31.4516129032258, Blast_Score=136, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_NOVAD (Q2G995)

Other databases:

- EMBL:   CP000248
- RefSeq:   YP_496412.1
- ProteinModelPortal:   Q2G995
- STRING:   Q2G995
- GeneID:   3916429
- GenomeReviews:   CP000248_GR
- KEGG:   nar:Saro_1133
- NMPDR:   fig|48935.1.peg.665
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- BioCyc:   NARO279238:SARO_1133-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 41344; Mature: 41213

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTVSRHYVLAAGGTGGHLIPAFALAVELDRRGHHVALVTDERGAKIPGKPDFLPAHVLP
CCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCHHCCC
AGRLGKNPVALFKGLRAIWQGRAMALRLFESFEPSCVIGFGGYPALPALLAAHAARIPTV
CCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHCCHH
IHEQNAVLGRVNRLLAKRVDAIATAYGEVDRLDPKLWGKVHRVGNPVRPDVLALRGEPFP
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEECCCCCC
EFTEDSLFRVLVTGGSQGASILSEVVPDGLAMLPPALRHRLQVTQQCRPEDLEVVRARYA
CCCHHCEEEEEEECCCCHHHHHHHHCCCCHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHH
AHEIPAELGTYFEDMQARLAGTHLFIGRAGASTIAELTAVGRPAILVPLPIATDDHQAAN
HHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCC
TREVVAAGGARAIRQSGFTPKELAKQIQAMAQHPHTLANAAHAAWNCGLPNAVKDLADLV
CHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHH
ESFGASPIMDVIRLDSTVSAASGQEQLA
HHHCCCHHHHHHHHCCHHHHCCCHHHCC
>Mature Secondary Structure 
TTVSRHYVLAAGGTGGHLIPAFALAVELDRRGHHVALVTDERGAKIPGKPDFLPAHVLP
CCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCHHCCC
AGRLGKNPVALFKGLRAIWQGRAMALRLFESFEPSCVIGFGGYPALPALLAAHAARIPTV
CCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHCCHH
IHEQNAVLGRVNRLLAKRVDAIATAYGEVDRLDPKLWGKVHRVGNPVRPDVLALRGEPFP
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEECCCCCC
EFTEDSLFRVLVTGGSQGASILSEVVPDGLAMLPPALRHRLQVTQQCRPEDLEVVRARYA
CCCHHCEEEEEEECCCCHHHHHHHHCCCCHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHH
AHEIPAELGTYFEDMQARLAGTHLFIGRAGASTIAELTAVGRPAILVPLPIATDDHQAAN
HHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCC
TREVVAAGGARAIRQSGFTPKELAKQIQAMAQHPHTLANAAHAAWNCGLPNAVKDLADLV
CHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHH
ESFGASPIMDVIRLDSTVSAASGQEQLA
HHHCCCHHHHHHHHCCHHHHCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA