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The map label for this gene is mrdB [H]

Identifier: 87199154

GI number: 87199154

Start: 1177766

End: 1178959

Strand: Direct

Name: mrdB [H]

Synonym: Saro_1132

Alternate gene names: 87199154

Gene position: 1177766-1178959 (Clockwise)

Preceding gene: 87199153

Following gene: 87199155

Centisome position: 33.07

GC content: 63.9

Gene sequence:

>1194_bases
ATGCCCGACGGCGGCGTGAAGGTTGTCGGCCACGGTTCGCGGTTCCGGCGCAGCAGGCGCAGTGAACTCCTTATCTGGTG
GCGCGAGATCGATCGCGTCCTGCTGGGACTTATCCTTTTCCTCGTGGCGATCGGCTGCATCGCCGTTGCCGCGGCAAGCC
CCGCCAGCGCGCATCGCCTCTCCACCAGCCAGAAGGCGCTGGGCGACCTCTACTTCTTCTGGATCCACCTGCGCTGGGTG
GTGGTCGGCATGGTCGCGATGTTCTTCGCCTCGGTCCTGCCCAAGGAAGCGGCCAGACGCGCCGCGATCCTGCTGGCGGC
GGCGATGCTCGTCGCGCTGGTTCTCGTGCCGCTCGTCGGCAGCGAGGTGAAGGGGGCCAAGCGCTGGCTGTGGATCGGCT
TCAGCCTCCAGCCTTCGGAGTTCCTCAAGCCGGGATTTGCGATCGCCATCGCGTGGATTTTGTCCTGGCGCGTGCGCGAT
CCCAACATTCCGGTCATTCCGATCACGATCGCCATCATGGGCCTCGTCGGCATCCTGCTGATGGCGCAGCCTGACTTCGG
GTCGACGGTTCTGTTCGGCGGCGTCTGGTTCGTGCTGGTGCTCTTGTCGGGGCTTTCGGTGAACCGCATCCTGTGGTCGA
TGGGCGGGGGCGTGGCGGCCGTTGTCGCGGCCTATCTGTTCTACCCGAACGCAACCCATCGCATCGACAACTTCATTTCC
GGCGGCAGCGAGTTCGACCAGGTCGACCTTGCCATGCGCACGCTTCTCAACGGCGGGTGGAGCGGTACCGGCCTCTGGCT
GGGCAGCCGCAAGAACGCGCTGCCCGAGGCGCATACCGACTATATCTTTTCGGTGATCGGTGAGGAATTCGGGCTGATCG
CCTGCGCGGTGGTCGTTGCCATCTATTGCATGATCGCGCTGCGCGTGCTGATGCGCCTGCTGGATGAAGAAGACCTGTTC
ACGATCCTTGCGGCGACCGGGCTGACGGCGCAGCTTGTCGGGCAGGCCTTCATCAACATCCTCGTCAACCTGCAACTCTT
TCCCTCGAAAGGCATGACCTTGCCGCTGATCAGCTACGGCGGATCGTCGACCATCGCGCTGCTCATGGGCGTCGGCTTCC
TGCTCGCGATCACCCGCCGCAATCCCTATCTGTCGAGAGAGAAGTTCGCGGTCACGGATCTGGTGCGCAAATGA

Upstream 100 bases:

>100_bases
AGATCGTCGAGGCGCTGATCGAGGATCGGGAAGCGCCCTGTCCGGACGGAACGCCGACGTGAGCACCACGCCAACCCCGA
CGCGCCTTGTCACCACCACC

Downstream 100 bases:

>100_bases
CGACAGTGTCCCGACACTATGTGCTGGCTGCCGGCGGCACCGGCGGACACCTGATCCCCGCTTTCGCGTTGGCCGTGGAA
CTGGACCGTCGCGGCCATCA

Product: cell cycle protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MPDGGVKVVGHGSRFRRSRRSELLIWWREIDRVLLGLILFLVAIGCIAVAAASPASAHRLSTSQKALGDLYFFWIHLRWV
VVGMVAMFFASVLPKEAARRAAILLAAAMLVALVLVPLVGSEVKGAKRWLWIGFSLQPSEFLKPGFAIAIAWILSWRVRD
PNIPVIPITIAIMGLVGILLMAQPDFGSTVLFGGVWFVLVLLSGLSVNRILWSMGGGVAAVVAAYLFYPNATHRIDNFIS
GGSEFDQVDLAMRTLLNGGWSGTGLWLGSRKNALPEAHTDYIFSVIGEEFGLIACAVVVAIYCMIALRVLMRLLDEEDLF
TILAATGLTAQLVGQAFINILVNLQLFPSKGMTLPLISYGGSSTIALLMGVGFLLAITRRNPYLSREKFAVTDLVRK

Sequences:

>Translated_397_residues
MPDGGVKVVGHGSRFRRSRRSELLIWWREIDRVLLGLILFLVAIGCIAVAAASPASAHRLSTSQKALGDLYFFWIHLRWV
VVGMVAMFFASVLPKEAARRAAILLAAAMLVALVLVPLVGSEVKGAKRWLWIGFSLQPSEFLKPGFAIAIAWILSWRVRD
PNIPVIPITIAIMGLVGILLMAQPDFGSTVLFGGVWFVLVLLSGLSVNRILWSMGGGVAAVVAAYLFYPNATHRIDNFIS
GGSEFDQVDLAMRTLLNGGWSGTGLWLGSRKNALPEAHTDYIFSVIGEEFGLIACAVVVAIYCMIALRVLMRLLDEEDLF
TILAATGLTAQLVGQAFINILVNLQLFPSKGMTLPLISYGGSSTIALLMGVGFLLAITRRNPYLSREKFAVTDLVRK
>Mature_396_residues
PDGGVKVVGHGSRFRRSRRSELLIWWREIDRVLLGLILFLVAIGCIAVAAASPASAHRLSTSQKALGDLYFFWIHLRWVV
VGMVAMFFASVLPKEAARRAAILLAAAMLVALVLVPLVGSEVKGAKRWLWIGFSLQPSEFLKPGFAIAIAWILSWRVRDP
NIPVIPITIAIMGLVGILLMAQPDFGSTVLFGGVWFVLVLLSGLSVNRILWSMGGGVAAVVAAYLFYPNATHRIDNFISG
GSEFDQVDLAMRTLLNGGWSGTGLWLGSRKNALPEAHTDYIFSVIGEEFGLIACAVVVAIYCMIALRVLMRLLDEEDLFT
ILAATGLTAQLVGQAFINILVNLQLFPSKGMTLPLISYGGSSTIALLMGVGFLLAITRRNPYLSREKFAVTDLVRK

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=377, Percent_Identity=31.2997347480106, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786853, Length=326, Percent_Identity=29.4478527607362, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 43229; Mature: 43098

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDGGVKVVGHGSRFRRSRRSELLIWWREIDRVLLGLILFLVAIGCIAVAAASPASAHRL
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
STSQKALGDLYFFWIHLRWVVVGMVAMFFASVLPKEAARRAAILLAAAMLVALVLVPLVG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
SEVKGAKRWLWIGFSLQPSEFLKPGFAIAIAWILSWRVRDPNIPVIPITIAIMGLVGILL
CCCCCCCEEEEEEEECCHHHHHCCHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHH
MAQPDFGSTVLFGGVWFVLVLLSGLSVNRILWSMGGGVAAVVAAYLFYPNATHRIDNFIS
HCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHC
GGSEFDQVDLAMRTLLNGGWSGTGLWLGSRKNALPEAHTDYIFSVIGEEFGLIACAVVVA
CCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IYCMIALRVLMRLLDEEDLFTILAATGLTAQLVGQAFINILVNLQLFPSKGMTLPLISYG
HHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHEEEECCCCCEEEEEECC
GSSTIALLMGVGFLLAITRRNPYLSREKFAVTDLVRK
CCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
PDGGVKVVGHGSRFRRSRRSELLIWWREIDRVLLGLILFLVAIGCIAVAAASPASAHRL
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
STSQKALGDLYFFWIHLRWVVVGMVAMFFASVLPKEAARRAAILLAAAMLVALVLVPLVG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
SEVKGAKRWLWIGFSLQPSEFLKPGFAIAIAWILSWRVRDPNIPVIPITIAIMGLVGILL
CCCCCCCEEEEEEEECCHHHHHCCHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHH
MAQPDFGSTVLFGGVWFVLVLLSGLSVNRILWSMGGGVAAVVAAYLFYPNATHRIDNFIS
HCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHC
GGSEFDQVDLAMRTLLNGGWSGTGLWLGSRKNALPEAHTDYIFSVIGEEFGLIACAVVVA
CCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IYCMIALRVLMRLLDEEDLFTILAATGLTAQLVGQAFINILVNLQLFPSKGMTLPLISYG
HHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHEEEECCCCCEEEEEECC
GSSTIALLMGVGFLLAITRRNPYLSREKFAVTDLVRK
CCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]