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The map label for this gene is cycW [H]

Identifier: 87199142

GI number: 87199142

Start: 1165157

End: 1165819

Strand: Direct

Name: cycW [H]

Synonym: Saro_1120

Alternate gene names: 87199142

Gene position: 1165157-1165819 (Clockwise)

Preceding gene: 87199141

Following gene: 87199143

Centisome position: 32.71

GC content: 71.19

Gene sequence:

>663_bases
ATGATCGCGCGGCTGTGGCCTATCTTCACCCGCGACCTTGCCCTGCTTACGCGGGGGGCGCAGGGGCGGGGCGGGGCGGT
TCTGCCGCTGCTGTTCTTCCTTGCCGTAGCCATGCTGTTTCCCTTCGCGGTCGGCCCGGATGCGCGCCTGCTGGCTCGAA
CCGGGGCGGGCGTGATCTGGGTTGCGGCGCTGCTGGCGGCGATCCTTCCGCTGGACCGTCTGGTCGAGCCCGACCTTGAA
GCCGGGATGTTCGACCAGTGGGCCCTGCGCGGCATTTCCGAAGAGGCGCTGCTGCTGGTGCGCATCCTTGCCCACTGGCT
CAGCTTCGGCGTGCCGCTGATGGTCGCCGCGCCACTTTCCGCAGGGTTGCTGTCGCTCGACGCCGGGCAATTGCGCACGG
TCGAGATCGGGCTGCTGCTCGGAACGCCGGGGCTGGCGGCGATCGGCGTGACCATTGCCGCGTTGACGGCGGGCATGCGC
GCGGGTGCGGCGCTAGGCGGGTTGCTTGCGATTCCGCTGGCCGTGCCGCTCCTGATCTTCGGCGCCGGGTCGCTTCAGCC
GGGCGGAGAGGGCGGTTTGGCGCTGCTGGCGGCGTGTAGCCTGGTGGCGCTCGCCGTCGCGCCCTTCGCCGGCGGTGCGG
CGATTCGGGCAGGCAGGGAGTAG

Upstream 100 bases:

>100_bases
TCGAGGCCCATTGCGCGCGCGGCGGGGCAGTGGTCATCGCATCGCATCAGCCGCTCGCGCTCGAGCGCGTGCGGACGCTT
GCAATCCGGAACTTTCAGCC

Downstream 100 bases:

>100_bases
GACTTCGCGGCATTGAAGCGCAAATTCGTTGGCATTCGCGCAAACTGCTCTTAACTCAGGCGCCATGATGGCTCCTGCGA
TTGCTCCCGATACCATTTCC

Product: cytochrome c-type biogenesis protein CcmB

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycW [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MIARLWPIFTRDLALLTRGAQGRGGAVLPLLFFLAVAMLFPFAVGPDARLLARTGAGVIWVAALLAAILPLDRLVEPDLE
AGMFDQWALRGISEEALLLVRILAHWLSFGVPLMVAAPLSAGLLSLDAGQLRTVEIGLLLGTPGLAAIGVTIAALTAGMR
AGAALGGLLAIPLAVPLLIFGAGSLQPGGEGGLALLAACSLVALAVAPFAGGAAIRAGRE

Sequences:

>Translated_220_residues
MIARLWPIFTRDLALLTRGAQGRGGAVLPLLFFLAVAMLFPFAVGPDARLLARTGAGVIWVAALLAAILPLDRLVEPDLE
AGMFDQWALRGISEEALLLVRILAHWLSFGVPLMVAAPLSAGLLSLDAGQLRTVEIGLLLGTPGLAAIGVTIAALTAGMR
AGAALGGLLAIPLAVPLLIFGAGSLQPGGEGGLALLAACSLVALAVAPFAGGAAIRAGRE
>Mature_220_residues
MIARLWPIFTRDLALLTRGAQGRGGAVLPLLFFLAVAMLFPFAVGPDARLLARTGAGVIWVAALLAAILPLDRLVEPDLE
AGMFDQWALRGISEEALLLVRILAHWLSFGVPLMVAAPLSAGLLSLDAGQLRTVEIGLLLGTPGLAAIGVTIAALTAGMR
AGAALGGLLAIPLAVPLLIFGAGSLQPGGEGGLALLAACSLVALAVAPFAGGAAIRAGRE

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=217, Percent_Identity=39.63133640553, Blast_Score=101, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 22276; Mature: 22276

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIARLWPIFTRDLALLTRGAQGRGGAVLPLLFFLAVAMLFPFAVGPDARLLARTGAGVIW
CCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHH
VAALLAAILPLDRLVEPDLEAGMFDQWALRGISEEALLLVRILAHWLSFGVPLMVAAPLS
HHHHHHHHHCHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHCCHH
AGLLSLDAGQLRTVEIGLLLGTPGLAAIGVTIAALTAGMRAGAALGGLLAIPLAVPLLIF
HCCEECCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAGSLQPGGEGGLALLAACSLVALAVAPFAGGAAIRAGRE
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHCCCCC
>Mature Secondary Structure
MIARLWPIFTRDLALLTRGAQGRGGAVLPLLFFLAVAMLFPFAVGPDARLLARTGAGVIW
CCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHH
VAALLAAILPLDRLVEPDLEAGMFDQWALRGISEEALLLVRILAHWLSFGVPLMVAAPLS
HHHHHHHHHCHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHCCHH
AGLLSLDAGQLRTVEIGLLLGTPGLAAIGVTIAALTAGMRAGAALGGLLAIPLAVPLLIF
HCCEECCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAGSLQPGGEGGLALLAACSLVALAVAPFAGGAAIRAGRE
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]