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The map label for this gene is ccmA

Identifier: 87199141

GI number: 87199141

Start: 1164585

End: 1165160

Strand: Direct

Name: ccmA

Synonym: Saro_1119

Alternate gene names: 87199141

Gene position: 1164585-1165160 (Clockwise)

Preceding gene: 87199139

Following gene: 87199142

Centisome position: 32.7

GC content: 68.06

Gene sequence:

>576_bases
ATGCAAGAGTGCGGTCTCGTCGCCACGGATATTGCCTGCCGGCGCGGGGATCGCATTCTGTTCCGCGCGCTGTCGCTGGA
CGTGAAGGCGGGCGAGATCGTGCACCTTGCCGGCGCCAACGGCATCGGCAAGTCGAGCTTGATCCGCATCCTTGCCGGAT
TGCTGCGTCCCTTTGCCGGAACTGTCGAGCGGCGGGGCGCGATTGCGCTTTCGGACGAACGGCTGGCGCTCGACGGTCAC
CTTCCGCTCGAGGATGCGCTGCGCTTCTGGGATCGGATCGACCGGGCGGGCAGGCCCGAAGCGGAGTTCGGGCTCGACGA
TCTGCTGGACGTTCCGGTCCGCTATCTCTCCACCGGGCAGCGCAAGCGCGCGGCGCTTGCGCGGGTTGCCGCCAGCGGGG
CGCCTTTGTGGTTGCTGGACGAGCCGCTGAACGGCCTTGACGTGCATTGGAGCGAGCGGGCGCAGGAGGCGATCGAGGCC
CATTGCGCGCGCGGCGGGGCAGTGGTCATCGCATCGCATCAGCCGCTCGCGCTCGAGCGCGTGCGGACGCTTGCAATCCG
GAACTTTCAGCCATGA

Upstream 100 bases:

>100_bases
CGCGTCGCGCTCTGCGTCGGTCAGGCGGGCTACGGTCATTGCATGTCCTTTTCGTCGGCGTCCTTGGCAGGGCCTGCGCT
TTCCCCTATCGCGTCGCGCC

Downstream 100 bases:

>100_bases
TCGCGCGGCTGTGGCCTATCTTCACCCGCGACCTTGCCCTGCTTACGCGGGGGGCGCAGGGGCGGGGCGGGGCGGTTCTG
CCGCTGCTGTTCTTCCTTGC

Product: heme exporter protein CcmA

Products: NA

Alternate protein names: Heme exporter protein A

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MQECGLVATDIACRRGDRILFRALSLDVKAGEIVHLAGANGIGKSSLIRILAGLLRPFAGTVERRGAIALSDERLALDGH
LPLEDALRFWDRIDRAGRPEAEFGLDDLLDVPVRYLSTGQRKRAALARVAASGAPLWLLDEPLNGLDVHWSERAQEAIEA
HCARGGAVVIASHQPLALERVRTLAIRNFQP

Sequences:

>Translated_191_residues
MQECGLVATDIACRRGDRILFRALSLDVKAGEIVHLAGANGIGKSSLIRILAGLLRPFAGTVERRGAIALSDERLALDGH
LPLEDALRFWDRIDRAGRPEAEFGLDDLLDVPVRYLSTGQRKRAALARVAASGAPLWLLDEPLNGLDVHWSERAQEAIEA
HCARGGAVVIASHQPLALERVRTLAIRNFQP
>Mature_191_residues
MQECGLVATDIACRRGDRILFRALSLDVKAGEIVHLAGANGIGKSSLIRILAGLLRPFAGTVERRGAIALSDERLALDGH
LPLEDALRFWDRIDRAGRPEAEFGLDDLLDVPVRYLSTGQRKRAALARVAASGAPLWLLDEPLNGLDVHWSERAQEAIEA
HCARGGAVVIASHQPLALERVRTLAIRNFQP

Specific function: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system

COG id: COG4133

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain

Homologues:

Organism=Homo sapiens, GI27436953, Length=178, Percent_Identity=30.8988764044944, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI89111135, Length=173, Percent_Identity=29.4797687861272, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI87082064, Length=199, Percent_Identity=38.1909547738693, Blast_Score=99, Evalue=1e-22,
Organism=Escherichia coli, GI1788165, Length=156, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787105, Length=196, Percent_Identity=30.1020408163265, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI87081791, Length=187, Percent_Identity=33.6898395721925, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1788002, Length=173, Percent_Identity=33.5260115606936, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87082267, Length=153, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787041, Length=182, Percent_Identity=29.1208791208791, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1790467, Length=181, Percent_Identity=28.7292817679558, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI2367384, Length=192, Percent_Identity=29.6875, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1789593, Length=193, Percent_Identity=30.5699481865285, Blast_Score=61, Evalue=4e-11,
Organism=Escherichia coli, GI1787182, Length=175, Percent_Identity=31.4285714285714, Blast_Score=60, Evalue=1e-10,
Organism=Drosophila melanogaster, GI116007184, Length=181, Percent_Identity=30.939226519337, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221500365, Length=181, Percent_Identity=30.939226519337, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45552355, Length=147, Percent_Identity=32.6530612244898, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI45552363, Length=147, Percent_Identity=32.6530612244898, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI45552361, Length=147, Percent_Identity=32.6530612244898, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI45552337, Length=147, Percent_Identity=32.6530612244898, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI45552351, Length=147, Percent_Identity=32.6530612244898, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI45552345, Length=147, Percent_Identity=32.6530612244898, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI45552347, Length=147, Percent_Identity=32.6530612244898, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI45552341, Length=147, Percent_Identity=32.6530612244898, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI45552339, Length=147, Percent_Identity=32.6530612244898, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI45552335, Length=147, Percent_Identity=32.6530612244898, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24583969, Length=147, Percent_Identity=32.6530612244898, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI45552359, Length=147, Percent_Identity=32.6530612244898, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI45552353, Length=147, Percent_Identity=32.6530612244898, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI45550972, Length=147, Percent_Identity=32.6530612244898, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI45552357, Length=147, Percent_Identity=32.6530612244898, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI45552349, Length=147, Percent_Identity=32.6530612244898, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI45552343, Length=147, Percent_Identity=32.6530612244898, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24585091, Length=177, Percent_Identity=29.9435028248588, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI45550390, Length=179, Percent_Identity=29.0502793296089, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CCMA_NOVAD (Q2G9A9)

Other databases:

- EMBL:   CP000248
- RefSeq:   YP_496398.1
- ProteinModelPortal:   Q2G9A9
- SMR:   Q2G9A9
- STRING:   Q2G9A9
- GeneID:   3916415
- GenomeReviews:   CP000248_GR
- KEGG:   nar:Saro_1119
- eggNOG:   COG4133
- HOGENOM:   HBG758042
- OMA:   RENCLYD
- PhylomeDB:   Q2G9A9
- ProtClustDB:   CLSK843814
- BioCyc:   NARO279238:SARO_1119-MONOMER
- HAMAP:   MF_01707
- InterPro:   IPR003439
- InterPro:   IPR005895
- InterPro:   IPR003593
- PANTHER:   PTHR19222:SF5
- SMART:   SM00382
- TIGRFAMs:   TIGR01189

Pfam domain/function: PF00005 ABC_tran

EC number: =3.6.3.41

Molecular weight: Translated: 20793; Mature: 20793

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: PS00211 ABC_TRANSPORTER_1; PS50893 ABC_TRANSPORTER_2; PS51243 CCMA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQECGLVATDIACRRGDRILFRALSLDVKAGEIVHLAGANGIGKSSLIRILAGLLRPFAG
CCCCCEEHHHHHHHCCCCEEEHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHH
TVERRGAIALSDERLALDGHLPLEDALRFWDRIDRAGRPEAEFGLDDLLDVPVRYLSTGQ
HHHHCCCEEECCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCC
RKRAALARVAASGAPLWLLDEPLNGLDVHWSERAQEAIEAHCARGGAVVIASHQPLALER
HHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHH
VRTLAIRNFQP
HHHHHHCCCCC
>Mature Secondary Structure
MQECGLVATDIACRRGDRILFRALSLDVKAGEIVHLAGANGIGKSSLIRILAGLLRPFAG
CCCCCEEHHHHHHHCCCCEEEHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHH
TVERRGAIALSDERLALDGHLPLEDALRFWDRIDRAGRPEAEFGLDDLLDVPVRYLSTGQ
HHHHCCCEEECCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCC
RKRAALARVAASGAPLWLLDEPLNGLDVHWSERAQEAIEAHCARGGAVVIASHQPLALER
HHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHH
VRTLAIRNFQP
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA