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The map label for this gene is yfjP [H]

Identifier: 87199138

GI number: 87199138

Start: 1162772

End: 1163389

Strand: Direct

Name: yfjP [H]

Synonym: Saro_1116

Alternate gene names: 87199138

Gene position: 1162772-1163389 (Clockwise)

Preceding gene: 87199136

Following gene: 87199139

Centisome position: 32.65

GC content: 66.34

Gene sequence:

>618_bases
GTGGGTCTTAGCGCAGAGGCAATCCGCGAAGGACTGGACCATATTGCCGCCCGGTCTCCGGCGCTGGCCGATGCGATCGA
ACGCGTCGGATACCCCGAGCCGCGCATAAGGCCGACCGGCTATCGCACGCTGTTGCGCACGATTGTCGGGCAGCAGGTCA
GCGTGTCGGCGGCGGCATCGGTGTGGAACAAGCTGGAGGCCCTGCTGGGCGAAGACCTGCCCCCGCATGACCTGCTCGCG
GCCGACTTCGACGCGTTGCGCGCCTGCGGCCTGTCACGCCAGAAGCAGGGCTACGCGCGCAGTCTTTGCGAACTGGTGGT
ATCCGGCGAACTCGATTTCGATTCGCTGCCGCAGGACGACGAGGAGGCGATTGCCGAACTCGTGAAGATCAAGGGGATCG
GGCGCTGGTCGGCGGAAATCTACCTCCTGTTCGCGGAGGGGCGGCCTGATATCTGGCCGGCGGGCGACCTTGCAGTCCAG
GTGGGGCTGGGGCGATTGCTCGGACTGCCGGAACGTCCGAGCGAGAAGGATACGCGCGTCCTGGCCGAACAGTGGCGGCC
CCATCGCGGCGCGGCGGCGATCTTCACCTGGCATTGCTATAACAATCCGGCGCTGTAG

Upstream 100 bases:

>100_bases
AATCCCGCCCCCTGTTCGCCTTTGGAAGGGGCTGCTATCGCGTGGTTCCGGCTTTGGCAACTGCCGATCCGGCCATAATC
TTGCCAAGGAGAAAAAGGGC

Downstream 100 bases:

>100_bases
TCTCTTGCTGACAAGCATGTAGGCAAGAGGGACAGCCACAATGGGCAAGACGATCTTCATCACCGGCGGCGCATCGGGCA
TCGGCCGGGCGGTGGCGCAG

Product: HhH-GPD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MGLSAEAIREGLDHIAARSPALADAIERVGYPEPRIRPTGYRTLLRTIVGQQVSVSAAASVWNKLEALLGEDLPPHDLLA
ADFDALRACGLSRQKQGYARSLCELVVSGELDFDSLPQDDEEAIAELVKIKGIGRWSAEIYLLFAEGRPDIWPAGDLAVQ
VGLGRLLGLPERPSEKDTRVLAEQWRPHRGAAAIFTWHCYNNPAL

Sequences:

>Translated_205_residues
MGLSAEAIREGLDHIAARSPALADAIERVGYPEPRIRPTGYRTLLRTIVGQQVSVSAAASVWNKLEALLGEDLPPHDLLA
ADFDALRACGLSRQKQGYARSLCELVVSGELDFDSLPQDDEEAIAELVKIKGIGRWSAEIYLLFAEGRPDIWPAGDLAVQ
VGLGRLLGLPERPSEKDTRVLAEQWRPHRGAAAIFTWHCYNNPAL
>Mature_204_residues
GLSAEAIREGLDHIAARSPALADAIERVGYPEPRIRPTGYRTLLRTIVGQQVSVSAAASVWNKLEALLGEDLPPHDLLAA
DFDALRACGLSRQKQGYARSLCELVVSGELDFDSLPQDDEEAIAELVKIKGIGRWSAEIYLLFAEGRPDIWPAGDLAVQV
GLGRLLGLPERPSEKDTRVLAEQWRPHRGAAAIFTWHCYNNPAL

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7-methylguanine, O2- methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG0122

COG function: function code L; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkylbase DNA glycosidase alkA family [H]

Homologues:

Organism=Escherichia coli, GI1788383, Length=188, Percent_Identity=29.7872340425532, Blast_Score=66, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320990, Length=180, Percent_Identity=28.8888888888889, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: =3.2.2.21 [H]

Molecular weight: Translated: 22446; Mature: 22315

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLSAEAIREGLDHIAARSPALADAIERVGYPEPRIRPTGYRTLLRTIVGQQVSVSAAAS
CCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHH
VWNKLEALLGEDLPPHDLLAADFDALRACGLSRQKQGYARSLCELVVSGELDFDSLPQDD
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCH
EEAIAELVKIKGIGRWSAEIYLLFAEGRPDIWPAGDLAVQVGLGRLLGLPERPSEKDTRV
HHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHH
LAEQWRPHRGAAAIFTWHCYNNPAL
HHHHCCCCCCCEEEEEEEECCCCCC
>Mature Secondary Structure 
GLSAEAIREGLDHIAARSPALADAIERVGYPEPRIRPTGYRTLLRTIVGQQVSVSAAAS
CCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHH
VWNKLEALLGEDLPPHDLLAADFDALRACGLSRQKQGYARSLCELVVSGELDFDSLPQDD
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCH
EEAIAELVKIKGIGRWSAEIYLLFAEGRPDIWPAGDLAVQVGLGRLLGLPERPSEKDTRV
HHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHH
LAEQWRPHRGAAAIFTWHCYNNPAL
HHHHCCCCCCCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]