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The map label for this gene is irgA [H]

Identifier: 87198479

GI number: 87198479

Start: 497246

End: 499669

Strand: Direct

Name: irgA [H]

Synonym: Saro_0454

Alternate gene names: 87198479

Gene position: 497246-499669 (Clockwise)

Preceding gene: 87198478

Following gene: 87198481

Centisome position: 13.96

GC content: 62.25

Gene sequence:

>2424_bases
ATGCCGAAGTCAACCTACACTCGTGCTTTGCTGGCAGGCGCCTGCGCGCTCGCCTTCGCGCTGCCCGCGCATGCGCAGGA
CGCAGCCCAGGCCACCGAGGCAGAAGACACCAACCCCAACGTCATCATCGTGACCGCGCAGAACCGCGCGCAGAACCTCA
ACGACGTTCCGATCAAGATCGACGTCGTCTCCGGCGAGGAGCTGCAGAAGGCTGGCTTTGCCAGCATGAACGACGTCGGC
CAGATCGCGCCGGTCGTGCAGGTCAACCAGGACCAGGGCACCGTGAAGGTTTCGGTCCGCGGCGTCGGCACCACCTCGAA
TGACGAAGCGCAGGATACTTCGGTCGTCATCAATATCGACGGTGAGTACATCAACCGCCCGAACGTGATGGGCATGGCCC
TGTTCGACATCGACCGGGTCGAAGTGCTGCGCGGTCCCCAGGGTACGCTCTACGGCCGCAACTCGACCGGCGGTGCAATC
AACTTCATCACCCGCAAGCCCGGCAAGGAATTCGGGGTCAACGGCTCGATCAGCTACGGCAACTACAACGCGATCCGTGC
CGATGCCGGTATTGATCTGCCGCTGGGCGAGATCGCCGGCCTTCGCGTCGCCGGCTTCTACGATGAGCGCGATGGCTACA
GCAAGCACCCCGCAGGCGGTGGCTTCTTCGTGTTCCCGGCCTACGCCGCTGGCCGTTCTGACGACAACAAGTCGTACGGA
GGCCGCGCCTCGCTCCGCCTCGAGCCGACCGATCGTCTCTCGATCAACCTGGCGGCCGAGTATTCGCACCGTAGCTTCAC
CCCCGGCATCTTTGCCGCCGGCGACCTGAACGGTGCCGGCAACGGTCCCACCGGCGGTGCCTGCAACAACGGCTTCACCC
AGGTTGCACCGGAATATGCGCAAGTGCTCTGCGTTCCCAGCAACACCAACCTGCTCTCGAAGGTCGACCGCAGCAATTAT
GCAGCGCCGCTCTTCGGCATCGGCCATGTCAGCGATCACACCTGGGCCGCACGCGGACGTATCGAATATGAGCTGAGCGA
CGCGGCAACGATCACCTACATTGGCGGCTATCGCAAGTACTCGGGCGATCCCGGTCGCCTGACTCTGCCGACGATCTATC
AGTCGTTCGGCTACCAGGATGAAGCCAAGACGCAGAGCCACGAACTGCGCATCAACGGCACGGTCGGCGGCGTGGTCTAT
CAGGTCGGCGGCTTCTACTTCAAGGAAGACCTGGCCCGCGAAAGCGGCTTCATGCTGCCCAGCTTCGTCTTCGCCGACCC
GCTCAATGATCCCAGCCTGTTCGGCAAGCCGGGCACGTTCCTCAGCTACTTCGGCCGCTACGTCAAAAGCGACAGCAAAT
CGGTCTTCGGTCAGGTCGAGGTTCCGCTGGGCGACAAGCTGACCGCGATCGGTGGCCTGCGCTATACCGACAACAAGCGC
AACGCGACCTATCTCAACGTCGACCCCTTCCGCTTCAGCCTTGAGACCTTCTCGCTCGTACCGGACCCGTACATCGTCGG
CGCCGGTCCAGGCCGGAAGGACTTCAGCAAGGTGATGTATCTCACCACCATTCCGCTCAAGAGCAGCGACAGCAAGGTCA
CGTGGCTGGCTGGCCTGAACTTCAAGCCGAACAGCGACACCCTGATCTTCGTCAAGGCGTCGACCGGCTTCAAAGCTGGC
GGTTTCGACTCGGTCGGCACCTACAAGCCCGAGACCAACACCGCTTTCGAAGGCGGCTGGAAGCAGACCTTCGGTGATCA
TGGGCAGCACCAGTTCAACCTTGGCGCGTTCTACTACGACTACAAGGACCTGCAGGTTTCCGTACTGCTTGATACCGCCA
TCGGCGGCCAGATCTTCAATGCCGGCAAGGCGAAGATCTGGGGCATCGAAGCCTCGGCCGACATTGCCCTGGACGATCGC
ACCAACTTCCATGCCTCGGCCAACTACCTGAATGCCGAATACAAGGAGCTGCTCGCGCAGTTCAACGTGTTCGACACCAC
CGGCGAGATCAACGGCGTTGGCGATCTCGATCCCAACACCGACGGCATCCAGCAGCCGAACTTTGCCGGCAACCGCCCGC
CGTTCTCTCCGGAATGGGTGCTGACCGCCTCGCTCGACCACACTTTCCCGCTGGGCGATATGGGTGGCCTGACGGCGCGG
GTGAACACCACCTTCAAGAGCAAGTACTTCACCGACTTCTACAACTATCGCGACGGCACGCAGAGCGCGCTCAGCCAGAC
CGACGCGAGCCTCGAATACAAGCCCGAGAACGAGAAGTTCTCGATCACGGCGTTCGTCAAGAACATCGAAGGCACGCGCC
CGCTGACCTACGGCAGCTTCGTTTCGGCCGGACCGGACGACATCTTCAACTGGCAGTTCGGCACGCCGCGCACCTACGGC
GTCCGCCTCGCGGTCGACTTCTAA

Upstream 100 bases:

>100_bases
AACGTTCTGCACTCAATAGAATTTAGGTTCTAGTTTTTAGAATTCTAATCTGTTAAACGGCGGCGCCGAACGTGGCGCAA
CATGGGGAGGAAATACCATC

Downstream 100 bases:

>100_bases
GTCGTACTCAGGTTCGCAAAACAGAAAGGGGAGCGGTTCGCCGCTCCCCTTTTTTGTTGCCGGAAGCCCCGGAGCGTTCA
GCCCCAGGACGGGTCCTTGC

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 807; Mature: 806

Protein sequence:

>807_residues
MPKSTYTRALLAGACALAFALPAHAQDAAQATEAEDTNPNVIIVTAQNRAQNLNDVPIKIDVVSGEELQKAGFASMNDVG
QIAPVVQVNQDQGTVKVSVRGVGTTSNDEAQDTSVVINIDGEYINRPNVMGMALFDIDRVEVLRGPQGTLYGRNSTGGAI
NFITRKPGKEFGVNGSISYGNYNAIRADAGIDLPLGEIAGLRVAGFYDERDGYSKHPAGGGFFVFPAYAAGRSDDNKSYG
GRASLRLEPTDRLSINLAAEYSHRSFTPGIFAAGDLNGAGNGPTGGACNNGFTQVAPEYAQVLCVPSNTNLLSKVDRSNY
AAPLFGIGHVSDHTWAARGRIEYELSDAATITYIGGYRKYSGDPGRLTLPTIYQSFGYQDEAKTQSHELRINGTVGGVVY
QVGGFYFKEDLARESGFMLPSFVFADPLNDPSLFGKPGTFLSYFGRYVKSDSKSVFGQVEVPLGDKLTAIGGLRYTDNKR
NATYLNVDPFRFSLETFSLVPDPYIVGAGPGRKDFSKVMYLTTIPLKSSDSKVTWLAGLNFKPNSDTLIFVKASTGFKAG
GFDSVGTYKPETNTAFEGGWKQTFGDHGQHQFNLGAFYYDYKDLQVSVLLDTAIGGQIFNAGKAKIWGIEASADIALDDR
TNFHASANYLNAEYKELLAQFNVFDTTGEINGVGDLDPNTDGIQQPNFAGNRPPFSPEWVLTASLDHTFPLGDMGGLTAR
VNTTFKSKYFTDFYNYRDGTQSALSQTDASLEYKPENEKFSITAFVKNIEGTRPLTYGSFVSAGPDDIFNWQFGTPRTYG
VRLAVDF

Sequences:

>Translated_807_residues
MPKSTYTRALLAGACALAFALPAHAQDAAQATEAEDTNPNVIIVTAQNRAQNLNDVPIKIDVVSGEELQKAGFASMNDVG
QIAPVVQVNQDQGTVKVSVRGVGTTSNDEAQDTSVVINIDGEYINRPNVMGMALFDIDRVEVLRGPQGTLYGRNSTGGAI
NFITRKPGKEFGVNGSISYGNYNAIRADAGIDLPLGEIAGLRVAGFYDERDGYSKHPAGGGFFVFPAYAAGRSDDNKSYG
GRASLRLEPTDRLSINLAAEYSHRSFTPGIFAAGDLNGAGNGPTGGACNNGFTQVAPEYAQVLCVPSNTNLLSKVDRSNY
AAPLFGIGHVSDHTWAARGRIEYELSDAATITYIGGYRKYSGDPGRLTLPTIYQSFGYQDEAKTQSHELRINGTVGGVVY
QVGGFYFKEDLARESGFMLPSFVFADPLNDPSLFGKPGTFLSYFGRYVKSDSKSVFGQVEVPLGDKLTAIGGLRYTDNKR
NATYLNVDPFRFSLETFSLVPDPYIVGAGPGRKDFSKVMYLTTIPLKSSDSKVTWLAGLNFKPNSDTLIFVKASTGFKAG
GFDSVGTYKPETNTAFEGGWKQTFGDHGQHQFNLGAFYYDYKDLQVSVLLDTAIGGQIFNAGKAKIWGIEASADIALDDR
TNFHASANYLNAEYKELLAQFNVFDTTGEINGVGDLDPNTDGIQQPNFAGNRPPFSPEWVLTASLDHTFPLGDMGGLTAR
VNTTFKSKYFTDFYNYRDGTQSALSQTDASLEYKPENEKFSITAFVKNIEGTRPLTYGSFVSAGPDDIFNWQFGTPRTYG
VRLAVDF
>Mature_806_residues
PKSTYTRALLAGACALAFALPAHAQDAAQATEAEDTNPNVIIVTAQNRAQNLNDVPIKIDVVSGEELQKAGFASMNDVGQ
IAPVVQVNQDQGTVKVSVRGVGTTSNDEAQDTSVVINIDGEYINRPNVMGMALFDIDRVEVLRGPQGTLYGRNSTGGAIN
FITRKPGKEFGVNGSISYGNYNAIRADAGIDLPLGEIAGLRVAGFYDERDGYSKHPAGGGFFVFPAYAAGRSDDNKSYGG
RASLRLEPTDRLSINLAAEYSHRSFTPGIFAAGDLNGAGNGPTGGACNNGFTQVAPEYAQVLCVPSNTNLLSKVDRSNYA
APLFGIGHVSDHTWAARGRIEYELSDAATITYIGGYRKYSGDPGRLTLPTIYQSFGYQDEAKTQSHELRINGTVGGVVYQ
VGGFYFKEDLARESGFMLPSFVFADPLNDPSLFGKPGTFLSYFGRYVKSDSKSVFGQVEVPLGDKLTAIGGLRYTDNKRN
ATYLNVDPFRFSLETFSLVPDPYIVGAGPGRKDFSKVMYLTTIPLKSSDSKVTWLAGLNFKPNSDTLIFVKASTGFKAGG
FDSVGTYKPETNTAFEGGWKQTFGDHGQHQFNLGAFYYDYKDLQVSVLLDTAIGGQIFNAGKAKIWGIEASADIALDDRT
NFHASANYLNAEYKELLAQFNVFDTTGEINGVGDLDPNTDGIQQPNFAGNRPPFSPEWVLTASLDHTFPLGDMGGLTARV
NTTFKSKYFTDFYNYRDGTQSALSQTDASLEYKPENEKFSITAFVKNIEGTRPLTYGSFVSAGPDDIFNWQFGTPRTYGV
RLAVDF

Specific function: Involved in the initial step of iron uptake by binding ferric vibriobactin, an iron chelatin siderophore that allows V.cholerae to extract iron from the environment [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=161, Percent_Identity=31.055900621118, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1790405, Length=218, Percent_Identity=30.2752293577982, Blast_Score=77, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 87392; Mature: 87261

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKSTYTRALLAGACALAFALPAHAQDAAQATEAEDTNPNVIIVTAQNRAQNLNDVPIKI
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCEEE
DVVSGEELQKAGFASMNDVGQIAPVVQVNQDQGTVKVSVRGVGTTSNDEAQDTSVVINID
EEECCHHHHHCCCCCCCCCCCCCCEEEECCCCCEEEEEEEECCCCCCCCCCCCEEEEEEC
GEYINRPNVMGMALFDIDRVEVLRGPQGTLYGRNSTGGAINFITRKPGKEFGVNGSISYG
CCCCCCCCEEEEEEEECCHHHEEECCCCEEEECCCCCCEEEEEECCCCHHHCCCCEEECC
NYNAIRADAGIDLPLGEIAGLRVAGFYDERDGYSKHPAGGGFFVFPAYAAGRSDDNKSYG
CCEEEEECCCCCCCHHHHCCEEEEEEECCCCCCCCCCCCCEEEEEECEECCCCCCCCCCC
GRASLRLEPTDRLSINLAAEYSHRSFTPGIFAAGDLNGAGNGPTGGACNNGFTQVAPEYA
CEEEEEECCCCCEEEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHCCCCCE
QVLCVPSNTNLLSKVDRSNYAAPLFGIGHVSDHTWAARGRIEYELSDAATITYIGGYRKY
EEEEECCCCHHHHHHCCCCCCCCEEEECCCCCCCEEECCEEEEEECCCEEEEEECCEEEC
SGDPGRLTLPTIYQSFGYQDEAKTQSHELRINGTVGGVVYQVGGFYFKEDLARESGFMLP
CCCCCCEEHHHHHHHCCCCCCCCCCCEEEEECCEECEEEEECCCCHHHHHHHHHCCCCCC
SFVFADPLNDPSLFGKPGTFLSYFGRYVKSDSKSVFGQVEVPLGDKLTAIGGLRYTDNKR
HHHEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEECCEEEECCCC
NATYLNVDPFRFSLETFSLVPDPYIVGAGPGRKDFSKVMYLTTIPLKSSDSKVTWLAGLN
CEEEEECCCEEEEEEEEEECCCCEEEECCCCHHHHCEEEEEEEECCCCCCCEEEEEEECC
FKPNSDTLIFVKASTGFKAGGFDSVGTYKPETNTAFEGGWKQTFGDHGQHQFNLGAFYYD
CCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCEEEEEEEEEEE
YKDLQVSVLLDTAIGGQIFNAGKAKIWGIEASADIALDDRTNFHASANYLNAEYKELLAQ
CCCEEEEEEEEECCCCEEECCCCEEEEEEECCCEEEECCCCCCEECCCCCCHHHHHHHHH
FNVFDTTGEINGVGDLDPNTDGIQQPNFAGNRPPFSPEWVLTASLDHTFPLGDMGGLTAR
CCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEE
VNTTFKSKYFTDFYNYRDGTQSALSQTDASLEYKPENEKFSITAFVKNIEGTRPLTYGSF
EEEEECHHHHHHHHHCCCCHHHHHHHCCCCEEECCCCCCEEEEEEEECCCCCCCEEECCC
VSAGPDDIFNWQFGTPRTYGVRLAVDF
CCCCCCCCCEECCCCCCEEEEEEEEEC
>Mature Secondary Structure 
PKSTYTRALLAGACALAFALPAHAQDAAQATEAEDTNPNVIIVTAQNRAQNLNDVPIKI
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCEEE
DVVSGEELQKAGFASMNDVGQIAPVVQVNQDQGTVKVSVRGVGTTSNDEAQDTSVVINID
EEECCHHHHHCCCCCCCCCCCCCCEEEECCCCCEEEEEEEECCCCCCCCCCCCEEEEEEC
GEYINRPNVMGMALFDIDRVEVLRGPQGTLYGRNSTGGAINFITRKPGKEFGVNGSISYG
CCCCCCCCEEEEEEEECCHHHEEECCCCEEEECCCCCCEEEEEECCCCHHHCCCCEEECC
NYNAIRADAGIDLPLGEIAGLRVAGFYDERDGYSKHPAGGGFFVFPAYAAGRSDDNKSYG
CCEEEEECCCCCCCHHHHCCEEEEEEECCCCCCCCCCCCCEEEEEECEECCCCCCCCCCC
GRASLRLEPTDRLSINLAAEYSHRSFTPGIFAAGDLNGAGNGPTGGACNNGFTQVAPEYA
CEEEEEECCCCCEEEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHCCCCCE
QVLCVPSNTNLLSKVDRSNYAAPLFGIGHVSDHTWAARGRIEYELSDAATITYIGGYRKY
EEEEECCCCHHHHHHCCCCCCCCEEEECCCCCCCEEECCEEEEEECCCEEEEEECCEEEC
SGDPGRLTLPTIYQSFGYQDEAKTQSHELRINGTVGGVVYQVGGFYFKEDLARESGFMLP
CCCCCCEEHHHHHHHCCCCCCCCCCCEEEEECCEECEEEEECCCCHHHHHHHHHCCCCCC
SFVFADPLNDPSLFGKPGTFLSYFGRYVKSDSKSVFGQVEVPLGDKLTAIGGLRYTDNKR
HHHEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEECCEEEECCCC
NATYLNVDPFRFSLETFSLVPDPYIVGAGPGRKDFSKVMYLTTIPLKSSDSKVTWLAGLN
CEEEEECCCEEEEEEEEEECCCCEEEECCCCHHHHCEEEEEEEECCCCCCCEEEEEEECC
FKPNSDTLIFVKASTGFKAGGFDSVGTYKPETNTAFEGGWKQTFGDHGQHQFNLGAFYYD
CCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCEEEEEEEEEEE
YKDLQVSVLLDTAIGGQIFNAGKAKIWGIEASADIALDDRTNFHASANYLNAEYKELLAQ
CCCEEEEEEEEECCCCEEECCCCEEEEEEECCCEEEECCCCCCEECCCCCCHHHHHHHHH
FNVFDTTGEINGVGDLDPNTDGIQQPNFAGNRPPFSPEWVLTASLDHTFPLGDMGGLTAR
CCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEE
VNTTFKSKYFTDFYNYRDGTQSALSQTDASLEYKPENEKFSITAFVKNIEGTRPLTYGSF
EEEEECHHHHHHHHHCCCCHHHHHHHCCCCEEECCCCCCEEEEEEEECCCCCCCEEECCC
VSAGPDDIFNWQFGTPRTYGVRLAVDF
CCCCCCCCCEECCCCCCEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1406279; 2174861 [H]