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The map label for this gene is ctaC [H]

Identifier: 86751686

GI number: 86751686

Start: 5182619

End: 5183473

Strand: Reverse

Name: ctaC [H]

Synonym: RPB_4588

Alternate gene names: 86751686

Gene position: 5183473-5182619 (Counterclockwise)

Preceding gene: 86751688

Following gene: 86751685

Centisome position: 97.22

GC content: 63.27

Gene sequence:

>855_bases
ATGACGATGTCGATGGGCCGAATTGGCCGGCATTTGCTTTGCAGTGGAATTCTGGCAGCCGCGCTCGGCGTCGGCGGCGC
CGCTCACGCGGTCGAAGGCCAGCCCGCGCCGTGGGAGATGCAGCTTCAGAAGGCCGCGACCCCGGTGATGGAAAACATCG
TCTGGTTCCACAGCTTCCTGCTCTGGCTGATCACCGCGATCACGCTGTTCGTGCTGGCGCTGCTGGTGATCGTGGTGGTG
AAGTTCAACGCCAAGGCCAACCCGGTGCCGTCGAAGACCACGCACCACACGCTGATCGAGGTCGCCTGGACCATCGTCCC
GGTGCTGATCCTGGTCGCGGTCGCGGTGCCGTCGTTCCGCCTGCTGTTCTTCCAGCTCGATATTCCGAAGGCCGATGTCA
CCATCAAGGCGACCGGCAATCAGTGGAACTGGACCTACAATTATCCCGACGACAAGATCGAGTTCACCTCGATCATGCTG
ACGGACGAAGAACGTTCGAAAATGAATCCGGTGCCGCCGCGGCTGCTCGCGGTCGACAACGAAACGGTCGTCCCGGTCAA
CAAGGTGGTGCGGATCCAGACCACCGCCGCCGACGTGATCCACTCCTGGGCGATCCCGTCCTTCGGCGTCAAGATCGACG
CCATTCCCGGCCGCCTCAACGAGACCTGGTTCAGGGCCACCAAGGAAGGCCGTTACTACGGCCAGTGCTCGGAACTTTGC
GGCAAGGACCACGCTTTCATGCCCATCGTCGTCCGCGTCGTCAGCGACCAGGAATACGACGCCTGGAAGAAGCAGCAGCA
GGTCGCCTCCCGCGGCGGCAAGTCCTACGCCTCGGTGGGCGCCGCCGCGCAGTGA

Upstream 100 bases:

>100_bases
GCATTCTTAAGGGGGCATAGCGTCGCACACCCTCGAGGATGAAAGGGCACTGCGCAACCAAGCGGCAGGTCCGGAAAAGA
CATAGGGGAGCGAAGGCGGC

Downstream 100 bases:

>100_bases
TCGGTCACGGCGCGCGCTACGTCTGAACGGGGACCGCAAGGTTCGAAGGTTTCAAGTCAGGATCTGAACATGACGATGGA
AGCTGCAAGGGTTGCTCATT

Product: cytochrome-c oxidase

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II [H]

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MTMSMGRIGRHLLCSGILAAALGVGGAAHAVEGQPAPWEMQLQKAATPVMENIVWFHSFLLWLITAITLFVLALLVIVVV
KFNAKANPVPSKTTHHTLIEVAWTIVPVLILVAVAVPSFRLLFFQLDIPKADVTIKATGNQWNWTYNYPDDKIEFTSIML
TDEERSKMNPVPPRLLAVDNETVVPVNKVVRIQTTAADVIHSWAIPSFGVKIDAIPGRLNETWFRATKEGRYYGQCSELC
GKDHAFMPIVVRVVSDQEYDAWKKQQQVASRGGKSYASVGAAAQ

Sequences:

>Translated_284_residues
MTMSMGRIGRHLLCSGILAAALGVGGAAHAVEGQPAPWEMQLQKAATPVMENIVWFHSFLLWLITAITLFVLALLVIVVV
KFNAKANPVPSKTTHHTLIEVAWTIVPVLILVAVAVPSFRLLFFQLDIPKADVTIKATGNQWNWTYNYPDDKIEFTSIML
TDEERSKMNPVPPRLLAVDNETVVPVNKVVRIQTTAADVIHSWAIPSFGVKIDAIPGRLNETWFRATKEGRYYGQCSELC
GKDHAFMPIVVRVVSDQEYDAWKKQQQVASRGGKSYASVGAAAQ
>Mature_283_residues
TMSMGRIGRHLLCSGILAAALGVGGAAHAVEGQPAPWEMQLQKAATPVMENIVWFHSFLLWLITAITLFVLALLVIVVVK
FNAKANPVPSKTTHHTLIEVAWTIVPVLILVAVAVPSFRLLFFQLDIPKADVTIKATGNQWNWTYNYPDDKIEFTSIMLT
DEERSKMNPVPPRLLAVDNETVVPVNKVVRIQTTAADVIHSWAIPSFGVKIDAIPGRLNETWFRATKEGRYYGQCSELCG
KDHAFMPIVVRVVSDQEYDAWKKQQQVASRGGKSYASVGAAAQ

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=217, Percent_Identity=41.0138248847926, Blast_Score=178, Evalue=5e-45,
Organism=Saccharomyces cerevisiae, GI6226540, Length=241, Percent_Identity=40.2489626556017, Blast_Score=172, Evalue=8e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 31380; Mature: 31249

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMSMGRIGRHLLCSGILAAALGVGGAAHAVEGQPAPWEMQLQKAATPVMENIVWFHSFL
CCCCHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LWLITAITLFVLALLVIVVVKFNAKANPVPSKTTHHTLIEVAWTIVPVLILVAVAVPSFR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEE
LLFFQLDIPKADVTIKATGNQWNWTYNYPDDKIEFTSIMLTDEERSKMNPVPPRLLAVDN
EEEEEEECCCCCEEEEECCCCCEEEECCCCCCEEEEEEEEECCHHHCCCCCCCEEEEECC
ETVVPVNKVVRIQTTAADVIHSWAIPSFGVKIDAIPGRLNETWFRATKEGRYYGQCSELC
CCEECHHHEEEEEHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHCCCCCCHHHHHC
GKDHAFMPIVVRVVSDQEYDAWKKQQQVASRGGKSYASVGAAAQ
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHCCCCCC
>Mature Secondary Structure 
TMSMGRIGRHLLCSGILAAALGVGGAAHAVEGQPAPWEMQLQKAATPVMENIVWFHSFL
CCCHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LWLITAITLFVLALLVIVVVKFNAKANPVPSKTTHHTLIEVAWTIVPVLILVAVAVPSFR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEE
LLFFQLDIPKADVTIKATGNQWNWTYNYPDDKIEFTSIMLTDEERSKMNPVPPRLLAVDN
EEEEEEECCCCCEEEEECCCCCEEEECCCCCCEEEEEEEEECCHHHCCCCCCCEEEEECC
ETVVPVNKVVRIQTTAADVIHSWAIPSFGVKIDAIPGRLNETWFRATKEGRYYGQCSELC
CCEECHHHEEEEEHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHCCCCCCHHHHHC
GKDHAFMPIVVRVVSDQEYDAWKKQQQVASRGGKSYASVGAAAQ
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA