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The map label for this gene is ctaD [H]

Identifier: 86751685

GI number: 86751685

Start: 5180924

End: 5182549

Strand: Reverse

Name: ctaD [H]

Synonym: RPB_4587

Alternate gene names: 86751685

Gene position: 5182549-5180924 (Counterclockwise)

Preceding gene: 86751686

Following gene: 86751684

Centisome position: 97.2

GC content: 63.16

Gene sequence:

>1626_bases
ATGACGATGGAAGCTGCAAGGGTTGCTCATTCCGATCACGCGCACGACGATCACGCCCATGCGCATCCGACCGGGTGGCG
GCGCTACGTCTACTCGACCAATCACAAGGACATCGGCACGATGTATCTGATCTTCGCGATCGTCGCGGGGATTATCGGCG
GTGCGATGTCGATCGCGATCCGGATCGAGCTGATGTACCCCGGCGTGCAGATCTTCCACGAGAGCCACACCTACAACGTG
TTCGTTACCTCGCACGGCCTGATCATGATCTTCTTCATGGTGATGCCGGCGATGATCGGCGGGTTCGGCAACTGGTTCGT
GCCGCTGATGATCGGCGCGCCCGACATGGCGTTCCCGCGGATGAACAACATCTCGTTCTGGCTGCTGCCGGCGGCGTTCG
CGCTGTTGCTGATCTCGACCTTCGTCGAGGGCGAGCCGTCGTCGAACGGCGTCGGCGCGGGCTGGACGATGTACGCGCCG
CTGTCGACCTCGGGGCATCCCGGCCCCGCCGTCGATTTCGCCATCCTGGCGCTGCATCTGGCCGGCGCCTCCTCGATCCT
CGGCGCCATCAACTTCATCACCACGATCTTCAACATGCGCGCGCCCGGCATGACGCTGCACAAGATGCCGCTGTTCGTGT
GGTCGATCCTGGTCACCGTGTTCCTGCTGCTGCTGTCGCTGCCGGTGCTCGCCGGCGCCATCACCATGCTGCTGACCGAC
CGCAATTTCGGCACCACCTTCTTCTCCGCCGAAGGCGGCGGCGATCCGTTGCTGTTCCAGCATCTGTTCTGGTTCTTCGG
TCATCCCGAAGTCTACATCCTGATCCTGCCGGCGTTCGGCATGGTCAGCCAGATCGTCTCGACCTTCTCGAAGAAGCCGG
TGTTCGGCTATCTCGGCATGGCCTATGCGATGGTGGCGATCGGCGTGATCGGCTTCGTGGTGTGGGCGCACCACATGTAC
ACGGTCGGGATGTCGAGCACGACGCAGGCCTATTTCGTCGCCGCCACGATGGTGATCGCGGTGCCGACCGGGGTGAAGAT
CTTCTCCTGGATCGCCACGATGTGGGGCGGCTCGATCGAGTTCAAGACGCCGATGTTGTGGGCCGTCGGCTTCATCTTCC
TGTTCACCGTCGGCGGCGTCACCGGCGTGGTGCTGGCCAATGCCGGCGTCGACCGCGTGCTGCAGGACACCTATTACGTC
GTCGCGCACTTCCACTACGTGCTATCGCTCGGCGCCGTGTTCGGGATCTTCGCCGGCTGGTACTACTGGTTCCCGAAGAT
GTTCGGCTACATGTACTCGGAGACCATCGGCAAGCTGCATTTCTGGGTGACGTTCATCGGCGTCAACATGGTGTTCTTCC
CGCAGCACTTCCTCGGCCTGTCCGGCATGCCGCGGCGCTACGTCGACTATCCGGACGCGTTCGCCGGCTGGAACCTGGTG
TCGTCGATCGGCTCCTACATCTCCGGCTTCGCCGTGCTGATCTTCCTGTTCGGCATGGCGCTGGCCTTCATCCGCAAGGA
GAAGGCCGCCGACAATCCGTGGGGCGCCGGCGCCACCACGCTGGAATGGACGCTGTCGTCGCCGCCGCCGTTCCATCAGT
TCGAAGTGCTGCCGCAGGTCCGCTGA

Upstream 100 bases:

>100_bases
CTACGCCTCGGTGGGCGCCGCCGCGCAGTGATCGGTCACGGCGCGCGCTACGTCTGAACGGGGACCGCAAGGTTCGAAGG
TTTCAAGTCAGGATCTGAAC

Downstream 100 bases:

>100_bases
GGCGTTCGATCGAGAGCATCCGTCGCGGGTCGTCCGTCGGCGGATGCGTATAGAGAGACAGAGGTTCCGAATTGTCGGTC
ATAGACACCAACCAGATCGA

Product: cytochrome-c oxidase

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 541; Mature: 540

Protein sequence:

>541_residues
MTMEAARVAHSDHAHDDHAHAHPTGWRRYVYSTNHKDIGTMYLIFAIVAGIIGGAMSIAIRIELMYPGVQIFHESHTYNV
FVTSHGLIMIFFMVMPAMIGGFGNWFVPLMIGAPDMAFPRMNNISFWLLPAAFALLLISTFVEGEPSSNGVGAGWTMYAP
LSTSGHPGPAVDFAILALHLAGASSILGAINFITTIFNMRAPGMTLHKMPLFVWSILVTVFLLLLSLPVLAGAITMLLTD
RNFGTTFFSAEGGGDPLLFQHLFWFFGHPEVYILILPAFGMVSQIVSTFSKKPVFGYLGMAYAMVAIGVIGFVVWAHHMY
TVGMSSTTQAYFVAATMVIAVPTGVKIFSWIATMWGGSIEFKTPMLWAVGFIFLFTVGGVTGVVLANAGVDRVLQDTYYV
VAHFHYVLSLGAVFGIFAGWYYWFPKMFGYMYSETIGKLHFWVTFIGVNMVFFPQHFLGLSGMPRRYVDYPDAFAGWNLV
SSIGSYISGFAVLIFLFGMALAFIRKEKAADNPWGAGATTLEWTLSSPPPFHQFEVLPQVR

Sequences:

>Translated_541_residues
MTMEAARVAHSDHAHDDHAHAHPTGWRRYVYSTNHKDIGTMYLIFAIVAGIIGGAMSIAIRIELMYPGVQIFHESHTYNV
FVTSHGLIMIFFMVMPAMIGGFGNWFVPLMIGAPDMAFPRMNNISFWLLPAAFALLLISTFVEGEPSSNGVGAGWTMYAP
LSTSGHPGPAVDFAILALHLAGASSILGAINFITTIFNMRAPGMTLHKMPLFVWSILVTVFLLLLSLPVLAGAITMLLTD
RNFGTTFFSAEGGGDPLLFQHLFWFFGHPEVYILILPAFGMVSQIVSTFSKKPVFGYLGMAYAMVAIGVIGFVVWAHHMY
TVGMSSTTQAYFVAATMVIAVPTGVKIFSWIATMWGGSIEFKTPMLWAVGFIFLFTVGGVTGVVLANAGVDRVLQDTYYV
VAHFHYVLSLGAVFGIFAGWYYWFPKMFGYMYSETIGKLHFWVTFIGVNMVFFPQHFLGLSGMPRRYVDYPDAFAGWNLV
SSIGSYISGFAVLIFLFGMALAFIRKEKAADNPWGAGATTLEWTLSSPPPFHQFEVLPQVR
>Mature_540_residues
TMEAARVAHSDHAHDDHAHAHPTGWRRYVYSTNHKDIGTMYLIFAIVAGIIGGAMSIAIRIELMYPGVQIFHESHTYNVF
VTSHGLIMIFFMVMPAMIGGFGNWFVPLMIGAPDMAFPRMNNISFWLLPAAFALLLISTFVEGEPSSNGVGAGWTMYAPL
STSGHPGPAVDFAILALHLAGASSILGAINFITTIFNMRAPGMTLHKMPLFVWSILVTVFLLLLSLPVLAGAITMLLTDR
NFGTTFFSAEGGGDPLLFQHLFWFFGHPEVYILILPAFGMVSQIVSTFSKKPVFGYLGMAYAMVAIGVIGFVVWAHHMYT
VGMSSTTQAYFVAATMVIAVPTGVKIFSWIATMWGGSIEFKTPMLWAVGFIFLFTVGGVTGVVLANAGVDRVLQDTYYVV
AHFHYVLSLGAVFGIFAGWYYWFPKMFGYMYSETIGKLHFWVTFIGVNMVFFPQHFLGLSGMPRRYVDYPDAFAGWNLVS
SIGSYISGFAVLIFLFGMALAFIRKEKAADNPWGAGATTLEWTLSSPPPFHQFEVLPQVR

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=513, Percent_Identity=62.3781676413255, Blast_Score=601, Evalue=1e-172,
Organism=Escherichia coli, GI1786634, Length=523, Percent_Identity=43.7858508604207, Blast_Score=404, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6226519, Length=537, Percent_Identity=56.610800744879, Blast_Score=602, Evalue=1e-173,
Organism=Saccharomyces cerevisiae, GI6226524, Length=327, Percent_Identity=61.7737003058104, Blast_Score=409, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6226523, Length=252, Percent_Identity=56.7460317460317, Blast_Score=267, Evalue=3e-72,
Organism=Saccharomyces cerevisiae, GI6226522, Length=79, Percent_Identity=46.8354430379747, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6226521, Length=66, Percent_Identity=48.4848484848485, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 59625; Mature: 59494

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMEAARVAHSDHAHDDHAHAHPTGWRRYVYSTNHKDIGTMYLIFAIVAGIIGGAMSIAI
CCCCHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHEEEEE
RIELMYPGVQIFHESHTYNVFVTSHGLIMIFFMVMPAMIGGFGNWFVPLMIGAPDMAFPR
EEEEECCCEEEEECCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCC
MNNISFWLLPAAFALLLISTFVEGEPSSNGVGAGWTMYAPLSTSGHPGPAVDFAILALHL
CCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
AGASSILGAINFITTIFNMRAPGMTLHKMPLFVWSILVTVFLLLLSLPVLAGAITMLLTD
HCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
RNFGTTFFSAEGGGDPLLFQHLFWFFGHPEVYILILPAFGMVSQIVSTFSKKPVFGYLGM
CCCCCEEEECCCCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCCHHHHHH
AYAMVAIGVIGFVVWAHHMYTVGMSSTTQAYFVAATMVIAVPTGVKIFSWIATMWGGSIE
HHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEE
FKTPMLWAVGFIFLFTVGGVTGVVLANAGVDRVLQDTYYVVAHFHYVLSLGAVFGIFAGW
ECCHHHHHHHHHHHHHHHCHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YYWFPKMFGYMYSETIGKLHFWVTFIGVNMVFFPQHFLGLSGMPRRYVDYPDAFAGWNLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHH
SSIGSYISGFAVLIFLFGMALAFIRKEKAADNPWGAGATTLEWTLSSPPPFHQFEVLPQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHCCCCCC
R
C
>Mature Secondary Structure 
TMEAARVAHSDHAHDDHAHAHPTGWRRYVYSTNHKDIGTMYLIFAIVAGIIGGAMSIAI
CCCHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHEEEEE
RIELMYPGVQIFHESHTYNVFVTSHGLIMIFFMVMPAMIGGFGNWFVPLMIGAPDMAFPR
EEEEECCCEEEEECCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCC
MNNISFWLLPAAFALLLISTFVEGEPSSNGVGAGWTMYAPLSTSGHPGPAVDFAILALHL
CCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
AGASSILGAINFITTIFNMRAPGMTLHKMPLFVWSILVTVFLLLLSLPVLAGAITMLLTD
HCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
RNFGTTFFSAEGGGDPLLFQHLFWFFGHPEVYILILPAFGMVSQIVSTFSKKPVFGYLGM
CCCCCEEEECCCCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCCHHHHHH
AYAMVAIGVIGFVVWAHHMYTVGMSSTTQAYFVAATMVIAVPTGVKIFSWIATMWGGSIE
HHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEE
FKTPMLWAVGFIFLFTVGGVTGVVLANAGVDRVLQDTYYVVAHFHYVLSLGAVFGIFAGW
ECCHHHHHHHHHHHHHHHCHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YYWFPKMFGYMYSETIGKLHFWVTFIGVNMVFFPQHFLGLSGMPRRYVDYPDAFAGWNLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHH
SSIGSYISGFAVLIFLFGMALAFIRKEKAADNPWGAGATTLEWTLSSPPPFHQFEVLPQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHCCCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2172930; 1965217; 12597275 [H]