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The map label for this gene is ahpF [C]

Identifier: 86751059

GI number: 86751059

Start: 4511415

End: 4512305

Strand: Reverse

Name: ahpF [C]

Synonym: RPB_3951

Alternate gene names: 86751059

Gene position: 4512305-4511415 (Counterclockwise)

Preceding gene: 86751060

Following gene: 86751057

Centisome position: 84.63

GC content: 71.49

Gene sequence:

>891_bases
ATGCAGCACGACGTGATCGTGATCGGCGGCAGCTATGCGGGCATGGCCGCAGCACTCCAGCTGCTGCGCGCCCGCCGCAG
CGTGCTGGTGATCGACGCCGGTGAGCGGCGCAACCGCTTCGCCGCGCATTCGCACGGCTTCCTCGGCCAGGACGGCGCCG
ATCCGGCGGCGATCGCCGCCTCGGCGCGTCGGCAAATCGAAACCTACAAGACGCTGCGCTGGATCGACGGCGTCGCCGAC
GCCGCGTCAGGCTGCAAAGACGACTTCACCGTGACGACGCGCGACGGCGCGCAGCATCGCGGGCGACGATTGCTATTCGC
GACCGGCGTGTCGGATCGTCTGCCGGCGATCGAGGGGCTGCAGCCGCGCTGGGGCGTCAGCGTGTTTCTCTGCCCGTATT
GCCACGGCTACGAACTCGACCAGGGCCGCATCGCGGTGATCGCCACCGGGCCGATGTCGCTGCATCAGGCGCAATTGCTG
CCGGAATGGGGCGAGGTCACGCTGTTCACCAACGCTGCAGTGGCGCCCGACGCCGCGGCGCGCGCCGACCTGACCGCGCG
CGGCGTGACCATCGAGGACTCGCCGATCGCGCGCGTCGACGGTCATGCCGACATCGTGCTGAGCGACGGCCGGCGGCTGG
CGTTCGCCGGCATCTTCACCACCTCGCACAACGCGCCGGCGTCGCCGGTCGCCGAGAGTCTCGGCTGCGCGCTGAGCGAG
ACGCCGTTCGGCACGCAGATCGCAACCGACGAGGCGAAACAGACCAGCGTGCCGGGCGCGTTCGCCTGCGGCGACGCGGC
GCGGGTGCCGCATTCGCTGTCGCTGGCGGTCGCCGACGGCGCCTGGGCCGGCGCCAGTCTGCATCGCTCGCTGGTGTGGC
CCGACGCCTGA

Upstream 100 bases:

>100_bases
CTGCTCGAACGCTTCGCCGAGGTGACGCTGGCGAAGCTGTCGGCGGATTTCAACCGGCGCCACGCGGCGCAGCGCGCCCG
AAAATAAAGGATTGATCGAC

Downstream 100 bases:

>100_bases
CGGCAGCCGGCGCGTGCGGCTACTTAAGCCTTCGCCGACGGCCGCGCCGCGATGCGCGCGTGCCATTCGGCGAGCACGGT
GTTGGCGGGATCGAGCGGCT

Product: FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Products: an alcohol; H2O; NAD [C]

Alternate protein names: Thioredoxin Reductase; Oxidoreductase; FAD-Dependent Pyridine Nucleotide-Disulfide Oxidoreductase; Reductase; Pyridine Nucleotide-Disulphide Oxidoreductase Class II; Thioredoxin-Disulfide Reductase; FAD Dependent Oxidoreductase; Pyridine Nucleotide-Disulphide Oxidoreductase; Thioredoxin Reductase Protein; Pyridine Nucleotide-Disulfide Oxidoreductase Domain Protein; Fad-Dependent Pyridine Nucleotide-Disulfide Oxidoreductase; Alkyl Hydroperoxide Reductase; Pyridine Nucleotide-Disulfide Oxidoreductase Family Protein; Pyridine Nucleotide-Disulfide Oxidoreductase; Oxidoreductase Protein; Methyltransferase; Methyltransferase Type; Disulfide Oxidoreductase; Alkyl Hydroperoxide Reductase Large Subunit

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MQHDVIVIGGSYAGMAAALQLLRARRSVLVIDAGERRNRFAAHSHGFLGQDGADPAAIAASARRQIETYKTLRWIDGVAD
AASGCKDDFTVTTRDGAQHRGRRLLFATGVSDRLPAIEGLQPRWGVSVFLCPYCHGYELDQGRIAVIATGPMSLHQAQLL
PEWGEVTLFTNAAVAPDAAARADLTARGVTIEDSPIARVDGHADIVLSDGRRLAFAGIFTTSHNAPASPVAESLGCALSE
TPFGTQIATDEAKQTSVPGAFACGDAARVPHSLSLAVADGAWAGASLHRSLVWPDA

Sequences:

>Translated_296_residues
MQHDVIVIGGSYAGMAAALQLLRARRSVLVIDAGERRNRFAAHSHGFLGQDGADPAAIAASARRQIETYKTLRWIDGVAD
AASGCKDDFTVTTRDGAQHRGRRLLFATGVSDRLPAIEGLQPRWGVSVFLCPYCHGYELDQGRIAVIATGPMSLHQAQLL
PEWGEVTLFTNAAVAPDAAARADLTARGVTIEDSPIARVDGHADIVLSDGRRLAFAGIFTTSHNAPASPVAESLGCALSE
TPFGTQIATDEAKQTSVPGAFACGDAARVPHSLSLAVADGAWAGASLHRSLVWPDA
>Mature_296_residues
MQHDVIVIGGSYAGMAAALQLLRARRSVLVIDAGERRNRFAAHSHGFLGQDGADPAAIAASARRQIETYKTLRWIDGVAD
AASGCKDDFTVTTRDGAQHRGRRLLFATGVSDRLPAIEGLQPRWGVSVFLCPYCHGYELDQGRIAVIATGPMSLHQAQLL
PEWGEVTLFTNAAVAPDAAARADLTARGVTIEDSPIARVDGHADIVLSDGRRLAFAGIFTTSHNAPASPVAESLGCALSE
TPFGTQIATDEAKQTSVPGAFACGDAARVPHSLSLAVADGAWAGASLHRSLVWPDA

Specific function: Serves To Protect The Cell Against DNA Damage By Alkyl Hydroperoxides. It Can Use Either NADH Or NADPH As Electron Donor For Direct Reduction Of Redox Dyes Or Of Alkyl Hydroperoxides When Combined With The Ahpc Protein. [C]

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.6.4.- [C]

Molecular weight: Translated: 31142; Mature: 31142

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHDVIVIGGSYAGMAAALQLLRARRSVLVIDAGERRNRFAAHSHGFLGQDGADPAAIAA
CCCCEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHH
SARRQIETYKTLRWIDGVADAASGCKDDFTVTTRDGAQHRGRRLLFATGVSDRLPAIEGL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHCCCEEEEEECCCCCCCCCCCC
QPRWGVSVFLCPYCHGYELDQGRIAVIATGPMSLHQAQLLPEWGEVTLFTNAAVAPDAAA
CCCCCCEEEEECCCCCEEECCCCEEEEEECCCHHHHHHHCCCCCCEEEEECCCCCCCCHH
RADLTARGVTIEDSPIARVDGHADIVLSDGRRLAFAGIFTTSHNAPASPVAESLGCALSE
HCCCEECCEEECCCCCEEECCCEEEEEECCCEEEEEEEEEECCCCCCCHHHHHHCCEECC
TPFGTQIATDEAKQTSVPGAFACGDAARVPHSLSLAVADGAWAGASLHRSLVWPDA
CCCCCEEECCCHHHCCCCCCEECCCHHHCCCEEEEEEECCCCCCCHHHHEECCCCC
>Mature Secondary Structure
MQHDVIVIGGSYAGMAAALQLLRARRSVLVIDAGERRNRFAAHSHGFLGQDGADPAAIAA
CCCCEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHH
SARRQIETYKTLRWIDGVADAASGCKDDFTVTTRDGAQHRGRRLLFATGVSDRLPAIEGL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHCCCEEEEEECCCCCCCCCCCC
QPRWGVSVFLCPYCHGYELDQGRIAVIATGPMSLHQAQLLPEWGEVTLFTNAAVAPDAAA
CCCCCCEEEEECCCCCEEECCCCEEEEEECCCHHHHHHHCCCCCCEEEEECCCCCCCCHH
RADLTARGVTIEDSPIARVDGHADIVLSDGRRLAFAGIFTTSHNAPASPVAESLGCALSE
HCCCEECCEEECCCCCEEECCCEEEEEECCCEEEEEEEEEECCCCCCCHHHHHHCCEECC
TPFGTQIATDEAKQTSVPGAFACGDAARVPHSLSLAVADGAWAGASLHRSLVWPDA
CCCCCEEECCCHHHCCCCCCEECCCHHHCCCEEEEEEECCCCCCCHHHHEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FAD. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ROOH; Proton; NADH [C]

Specific reaction: ROOH + Proton + NADH = an alcohol + H2O + NAD [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA