Click here to switch to the map view.

The map label for this gene is ycgM [C]

Identifier: 86750543

GI number: 86750543

Start: 3930758

End: 3931543

Strand: Direct

Name: ycgM [C]

Synonym: RPB_3432

Alternate gene names: 86750543

Gene position: 3930758-3931543 (Clockwise)

Preceding gene: 86750542

Following gene: 86750544

Centisome position: 73.72

GC content: 66.03

Gene sequence:

>786_bases
GTGACCAAATGGGTTCGCTTCCGCGCCGATGGCGCGATCGGCTTCGGCACCATCGCGCATTCCGACATCGCGGTGCATGA
CGGCGAGATGTTCGGCGCCAACACGCCGACCGGCCGGACGCTGCAGCTCGGCGACATCGAATTGCTGGCGCCCTGCGCGC
CCGGCAAGATCATCGGGCTGTGGAACAATTTTCACGCGCTGGCCGCCAAGCTCAATCAGTCGATCCCGCCCGAGCCGTTG
TACTTCCTGAAAGCGACCACCAGCGTCGCCGCGCATGGCGCCGTGGTGAACCGTCCCGCCTCCTACGACGGCAAGGTCGT
CTACGAAGGCGAACTCGGCATCGTCATCGGCAAACGGGCGAGCGGCATTTCCGAAGCCGAGGCGGCCGCGCACATCTTCG
GCTACACCTGCGTCAACGACATCACCGCGGCCGACATCCTCAATCGCGACCCGAGCTTCCCGCAATGGGCGCGCGCCAAG
AGCTTCGACGGCTTCGGCCCGTTCGGCCCGGCGATCGCCACCGGTCTCGATCCCGCCACGATGTCGATCCGCACCCTCCT
CAACGGCGCCGAGCGGCAGAATTACCCGGTCGCCGACATGGTGTTCCAGCCGCACAAGCTCGTCAGCCTGCTGTCGCACG
ACATGACGCTGGAGCCCGGCGACCTGATCTGCTGCGGCACCTCGGTCGGCGTCGGCGTGATGAAGGAGGCCGTCAACAGC
GTCACCATCGCGATCGAGGGCATCGGCGAACTGCACAACGAATTCCGTCAGGCGGCGAAAGCGTAG

Upstream 100 bases:

>100_bases
ATAACCACCGCCGGGGGATATGGATTCCGGGTCTGCGCCCAAGGGGCGCATCCCGGAATGACGAACATTGAGTTTGTCAT
TCGTATCAAGGAGACCCGCC

Downstream 100 bases:

>100_bases
CCTCCTGCACCGTCATTCCGGGGCACGCCGTCAGGCGCGAACCCGGACTCCGGAGGTCAGGCCACCCCACAGCGACGCAG
AACATCGGACGTAGAACAGA

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MTKWVRFRADGAIGFGTIAHSDIAVHDGEMFGANTPTGRTLQLGDIELLAPCAPGKIIGLWNNFHALAAKLNQSIPPEPL
YFLKATTSVAAHGAVVNRPASYDGKVVYEGELGIVIGKRASGISEAEAAAHIFGYTCVNDITAADILNRDPSFPQWARAK
SFDGFGPFGPAIATGLDPATMSIRTLLNGAERQNYPVADMVFQPHKLVSLLSHDMTLEPGDLICCGTSVGVGVMKEAVNS
VTIAIEGIGELHNEFRQAAKA

Sequences:

>Translated_261_residues
MTKWVRFRADGAIGFGTIAHSDIAVHDGEMFGANTPTGRTLQLGDIELLAPCAPGKIIGLWNNFHALAAKLNQSIPPEPL
YFLKATTSVAAHGAVVNRPASYDGKVVYEGELGIVIGKRASGISEAEAAAHIFGYTCVNDITAADILNRDPSFPQWARAK
SFDGFGPFGPAIATGLDPATMSIRTLLNGAERQNYPVADMVFQPHKLVSLLSHDMTLEPGDLICCGTSVGVGVMKEAVNS
VTIAIEGIGELHNEFRQAAKA
>Mature_260_residues
TKWVRFRADGAIGFGTIAHSDIAVHDGEMFGANTPTGRTLQLGDIELLAPCAPGKIIGLWNNFHALAAKLNQSIPPEPLY
FLKATTSVAAHGAVVNRPASYDGKVVYEGELGIVIGKRASGISEAEAAAHIFGYTCVNDITAADILNRDPSFPQWARAKS
FDGFGPFGPAIATGLDPATMSIRTLLNGAERQNYPVADMVFQPHKLVSLLSHDMTLEPGDLICCGTSVGVGVMKEAVNSV
TIAIEGIGELHNEFRQAAKA

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI40786394, Length=225, Percent_Identity=33.7777777777778, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI156231349, Length=226, Percent_Identity=33.1858407079646, Blast_Score=107, Evalue=8e-24,
Organism=Homo sapiens, GI13654274, Length=184, Percent_Identity=32.6086956521739, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI215422413, Length=184, Percent_Identity=32.6086956521739, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI66348062, Length=184, Percent_Identity=32.6086956521739, Blast_Score=92, Evalue=4e-19,
Organism=Escherichia coli, GI1787428, Length=196, Percent_Identity=28.0612244897959, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17557057, Length=179, Percent_Identity=32.4022346368715, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6324161, Length=218, Percent_Identity=27.9816513761468, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28572127, Length=222, Percent_Identity=33.3333333333333, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24663695, Length=221, Percent_Identity=33.4841628959276, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28571789, Length=185, Percent_Identity=36.7567567567568, Blast_Score=99, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 27659; Mature: 27528

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKWVRFRADGAIGFGTIAHSDIAVHDGEMFGANTPTGRTLQLGDIELLAPCAPGKIIGL
CCCEEEEEECCCEEECEEECCCEEEECCCEECCCCCCCCEEEECCEEEEECCCCCCEEEE
WNNFHALAAKLNQSIPPEPLYFLKATTSVAAHGAVVNRPASYDGKVVYEGELGIVIGKRA
CCCHHHHHHHHHCCCCCCCEEEEEEHHHHHHCCCEECCCCCCCCEEEEECCEEEEEECCC
SGISEAEAAAHIFGYTCVNDITAADILNRDPSFPQWARAKSFDGFGPFGPAIATGLDPAT
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCHHHHCCCCHHH
MSIRTLLNGAERQNYPVADMVFQPHKLVSLLSHDMTLEPGDLICCGTSVGVGVMKEAVNS
HHHHHHHCCHHCCCCCHHHHHCCHHHHHHHHHCCCEECCCCEEEECCCCCHHHHHHHHCE
VTIAIEGIGELHNEFRQAAKA
EEEEEECHHHHHHHHHHHHCC
>Mature Secondary Structure 
TKWVRFRADGAIGFGTIAHSDIAVHDGEMFGANTPTGRTLQLGDIELLAPCAPGKIIGL
CCEEEEEECCCEEECEEECCCEEEECCCEECCCCCCCCEEEECCEEEEECCCCCCEEEE
WNNFHALAAKLNQSIPPEPLYFLKATTSVAAHGAVVNRPASYDGKVVYEGELGIVIGKRA
CCCHHHHHHHHHCCCCCCCEEEEEEHHHHHHCCCEECCCCCCCCEEEEECCEEEEEECCC
SGISEAEAAAHIFGYTCVNDITAADILNRDPSFPQWARAKSFDGFGPFGPAIATGLDPAT
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCHHHHCCCCHHH
MSIRTLLNGAERQNYPVADMVFQPHKLVSLLSHDMTLEPGDLICCGTSVGVGVMKEAVNS
HHHHHHHCCHHCCCCCHHHHHCCHHHHHHHHHCCCEECCCCEEEECCCCCHHHHHHHHCE
VTIAIEGIGELHNEFRQAAKA
EEEEEECHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]