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The map label for this gene is efp

Identifier: 86750073

GI number: 86750073

Start: 3365514

End: 3366080

Strand: Direct

Name: efp

Synonym: RPB_2956

Alternate gene names: 86750073

Gene position: 3365514-3366080 (Clockwise)

Preceding gene: 86750069

Following gene: 86750074

Centisome position: 63.12

GC content: 61.73

Gene sequence:

>567_bases
TTGAGAGTCATCGCCAGTTCTATTCGCAAGGGCAACGTCCTCGAGCAAGATGGGAAGCTTTACGTCGTCCTGTCAGCCGA
AAACATCCATCCCGGCAAGGGAACTCCGGTCAGCCAGATCGAAATGCGCCGAATCAGCGACGGCGTGAAGATCTCGGAGC
GCTACAAGACCACCGACCAGGTCGAAAAGGCCACGATCGAAGAGCGCAATTACAGCTTCCTGTATGAAGACGGCGAAGGC
TTCCACTTCATGGAGCCGGAATCCTTCGACCAGGTTCAGGTCACCAAGGACGTGGTCGGCAACAGCGCGCCCTATCTGCA
GGAAGGCATGGTGGTGAAGCTGTCGATGCACGACACCGTCGCGGTCGCGATCACGCTGCCGCAGCGCGCCACCCTCGAAG
TGGTCGAGACCGAGCCGGTCACCAAGGGCCAGACCGCGTCGTCGTCCTACAAGCCGGCGGTGCTGTCGAACGGCGTCCGC
ACCGCGGTCCCGCCGCATGTCGGAGTCGGCACCCGGATCGTGGTGCTGACCGAAGACGGCTCCTATGTCGAGCGCGCCAA
GGACTGA

Upstream 100 bases:

>100_bases
GTCGGGGCAAATGGGTATGTTGCGGCCCGAAACCGTTTCGCAGGCCGCCGGATGCCAATGCCCGGATCGGGCCCGGATCT
GAACCACAGGAAATATTCCT

Downstream 100 bases:

>100_bases
GGCGCCTCGATCTCCCTGTCGAACACGACCAGCCCGCCGCATCCCGGCGGGCTTTTTCGTGGGTACGGAGCCCACATGCG
GCACCTGCGAACGCCCCGGG

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MRVIASSIRKGNVLEQDGKLYVVLSAENIHPGKGTPVSQIEMRRISDGVKISERYKTTDQVEKATIEERNYSFLYEDGEG
FHFMEPESFDQVQVTKDVVGNSAPYLQEGMVVKLSMHDTVAVAITLPQRATLEVVETEPVTKGQTASSSYKPAVLSNGVR
TAVPPHVGVGTRIVVLTEDGSYVERAKD

Sequences:

>Translated_188_residues
MRVIASSIRKGNVLEQDGKLYVVLSAENIHPGKGTPVSQIEMRRISDGVKISERYKTTDQVEKATIEERNYSFLYEDGEG
FHFMEPESFDQVQVTKDVVGNSAPYLQEGMVVKLSMHDTVAVAITLPQRATLEVVETEPVTKGQTASSSYKPAVLSNGVR
TAVPPHVGVGTRIVVLTEDGSYVERAKD
>Mature_188_residues
MRVIASSIRKGNVLEQDGKLYVVLSAENIHPGKGTPVSQIEMRRISDGVKISERYKTTDQVEKATIEERNYSFLYEDGEG
FHFMEPESFDQVQVTKDVVGNSAPYLQEGMVVKLSMHDTVAVAITLPQRATLEVVETEPVTKGQTASSSYKPAVLSNGVR
TAVPPHVGVGTRIVVLTEDGSYVERAKD

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=183, Percent_Identity=34.4262295081967, Blast_Score=127, Evalue=3e-31,
Organism=Escherichia coli, GI87082061, Length=186, Percent_Identity=33.8709677419355, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_RHOP2 (Q2IVV2)

Other databases:

- EMBL:   CP000250
- RefSeq:   YP_486569.1
- ProteinModelPortal:   Q2IVV2
- SMR:   Q2IVV2
- STRING:   Q2IVV2
- GeneID:   3910755
- GenomeReviews:   CP000250_GR
- KEGG:   rpb:RPB_2956
- eggNOG:   COG0231
- HOGENOM:   HBG303311
- OMA:   DNAECIV
- ProtClustDB:   PRK00529
- BioCyc:   RPAL316058:RPB_2956-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20656; Mature: 20656

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVIASSIRKGNVLEQDGKLYVVLSAENIHPGKGTPVSQIEMRRISDGVKISERYKTTDQ
CCCCHHHCCCCCEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCEEHHHHCCHHH
VEKATIEERNYSFLYEDGEGFHFMEPESFDQVQVTKDVVGNSAPYLQEGMVVKLSMHDTV
HHHHHHCCCCCEEEEECCCCEEEECCCCCCEEEEEHHHHCCCCCCCCCCEEEEEEECCEE
AVAITLPQRATLEVVETEPVTKGQTASSSYKPAVLSNGVRTAVPPHVGVGTRIVVLTEDG
EEEEECCCCCEEEEEECCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEEEECCC
SYVERAKD
CHHHCCCC
>Mature Secondary Structure
MRVIASSIRKGNVLEQDGKLYVVLSAENIHPGKGTPVSQIEMRRISDGVKISERYKTTDQ
CCCCHHHCCCCCEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCEEHHHHCCHHH
VEKATIEERNYSFLYEDGEGFHFMEPESFDQVQVTKDVVGNSAPYLQEGMVVKLSMHDTV
HHHHHHCCCCCEEEEECCCCEEEECCCCCCEEEEEHHHHCCCCCCCCCCEEEEEEECCEE
AVAITLPQRATLEVVETEPVTKGQTASSSYKPAVLSNGVRTAVPPHVGVGTRIVVLTEDG
EEEEECCCCCEEEEEECCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEEEECCC
SYVERAKD
CHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA