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The map label for this gene is nuoH1 [H]

Identifier: 86749699

GI number: 86749699

Start: 2962729

End: 2963754

Strand: Direct

Name: nuoH1 [H]

Synonym: RPB_2581

Alternate gene names: 86749699

Gene position: 2962729-2963754 (Clockwise)

Preceding gene: 86749698

Following gene: 86749700

Centisome position: 55.57

GC content: 63.26

Gene sequence:

>1026_bases
ATGGCTGATTTCTTCATGACCAACCTGTGGCCGCTGATCGTCGTGATCGGGCAGAGCGTGCTGCTGATCGTGGTGCTGCT
GATCTCGATCGCCTACATCCTGCTTGCCGACCGCAAGATCTGGGCGGCGGTGCAGATCCGGCGTGGCCCGAACGTGGTCG
GGCCGTGGGGCCTGCTGCAATCCTTCGCCGATTTGCTGAAGATGATCCTGAAGGAGCCGATGATCCCGTCCGGCGCCAAC
AAGGGCGTGTTCCTGCTGGCGCCTTTGGTGACCTGCGTGCTGGCGCTGTCGGCCTGGGCGGTGATCCCGGTCAGCGCCGG
CTGGGTGATCGCCGATATCAATGTCGGCGTGCTGTACATCCTGGCGGTGTCGTCGCTGTCGGTCTACGGCATCATCATGG
CCGGCTGGTCGTCGAACTCGAAATATCCGTTCCTGGCCGCGCTGCGCTCGGCGGCGCAGATGGTGTCCTACGAGGTCTCG
ATCGGTTTCGTGATTATCTGCGTGCTGCTGTGCGTCGGTTCACTCAACCTGACGGCGATCGTCCAGGCGCAGAACTCGCA
ATGGGGCGTCCTCGGCTGGTACTGGCTGCCGCTGTTTCCGATGTTCGTGGTGTTCTACGTCTCGGCGCTGGCCGAGACCA
ACCGGCCGCCGTTCGATCTGGTCGAAGCCGAATCCGAACTGGTCGCCGGGTTCATGGTCGAGTACTCGTCGACGCCCTAC
ATGCTGTTCGTGCTCGGCGAATACGTCGCGATCGTCACGATGTGCGCGATGGGCACGATCCTGTTTCTCGGCGGCTGGCT
GCCGCCGGTGCCCTACGCCCCGTTCACATGGGTGCCGGGGATCGTCTGGTTCGCGCTCAAAGTCCTGTTCATGTTCTTCA
TGTTCGCGATGGCGAAGGCGATCGTGCCGCGCTACCGCTACGACCAACTGATGCGGCTCGGCTGGAAGGTGTTCCTGCCG
CTGTCGCTGGCGATGGTGGTGATCGTCGCCGCCGTCCTGCAATTCGCGGGGCTCGCGCCGAAATGA

Upstream 100 bases:

>100_bases
CTACATGACCAACCCGATCGCGCGGGCGTCCGCCGTGATGGCGGAGTGCTCCCGCCTGGCGTCGGGGCAGATGCTGACGG
CGGCGGAGTAGGCGAGGCCC

Downstream 100 bases:

>100_bases
GGCCGTCATGAATATCAACGCAACCGCCCGTTCGCTGCTGCTGACGGAATTCGTATCGGCGTTCTTCCTCGCCATGCGCT
ATTTCTTCAAGCCGAAGCCG

Product: NADH dehydrogenase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H 1; NDH-1 subunit H 1 [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MADFFMTNLWPLIVVIGQSVLLIVVLLISIAYILLADRKIWAAVQIRRGPNVVGPWGLLQSFADLLKMILKEPMIPSGAN
KGVFLLAPLVTCVLALSAWAVIPVSAGWVIADINVGVLYILAVSSLSVYGIIMAGWSSNSKYPFLAALRSAAQMVSYEVS
IGFVIICVLLCVGSLNLTAIVQAQNSQWGVLGWYWLPLFPMFVVFYVSALAETNRPPFDLVEAESELVAGFMVEYSSTPY
MLFVLGEYVAIVTMCAMGTILFLGGWLPPVPYAPFTWVPGIVWFALKVLFMFFMFAMAKAIVPRYRYDQLMRLGWKVFLP
LSLAMVVIVAAVLQFAGLAPK

Sequences:

>Translated_341_residues
MADFFMTNLWPLIVVIGQSVLLIVVLLISIAYILLADRKIWAAVQIRRGPNVVGPWGLLQSFADLLKMILKEPMIPSGAN
KGVFLLAPLVTCVLALSAWAVIPVSAGWVIADINVGVLYILAVSSLSVYGIIMAGWSSNSKYPFLAALRSAAQMVSYEVS
IGFVIICVLLCVGSLNLTAIVQAQNSQWGVLGWYWLPLFPMFVVFYVSALAETNRPPFDLVEAESELVAGFMVEYSSTPY
MLFVLGEYVAIVTMCAMGTILFLGGWLPPVPYAPFTWVPGIVWFALKVLFMFFMFAMAKAIVPRYRYDQLMRLGWKVFLP
LSLAMVVIVAAVLQFAGLAPK
>Mature_340_residues
ADFFMTNLWPLIVVIGQSVLLIVVLLISIAYILLADRKIWAAVQIRRGPNVVGPWGLLQSFADLLKMILKEPMIPSGANK
GVFLLAPLVTCVLALSAWAVIPVSAGWVIADINVGVLYILAVSSLSVYGIIMAGWSSNSKYPFLAALRSAAQMVSYEVSI
GFVIICVLLCVGSLNLTAIVQAQNSQWGVLGWYWLPLFPMFVVFYVSALAETNRPPFDLVEAESELVAGFMVEYSSTPYM
LFVLGEYVAIVTMCAMGTILFLGGWLPPVPYAPFTWVPGIVWFALKVLFMFFMFAMAKAIVPRYRYDQLMRLGWKVFLPL
SLAMVVIVAAVLQFAGLAPK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=299, Percent_Identity=41.4715719063545, Blast_Score=234, Evalue=1e-61,
Organism=Escherichia coli, GI1788618, Length=326, Percent_Identity=41.1042944785276, Blast_Score=258, Evalue=5e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 37514; Mature: 37383

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADFFMTNLWPLIVVIGQSVLLIVVLLISIAYILLADRKIWAAVQIRRGPNVVGPWGLLQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCCCCCCHHHHHH
SFADLLKMILKEPMIPSGANKGVFLLAPLVTCVLALSAWAVIPVSAGWVIADINVGVLYI
HHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHEEECCCEEEEECCHHHHHH
LAVSSLSVYGIIMAGWSSNSKYPFLAALRSAAQMVSYEVSIGFVIICVLLCVGSLNLTAI
HHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
VQAQNSQWGVLGWYWLPLFPMFVVFYVSALAETNRPPFDLVEAESELVAGFMVEYSSTPY
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEECCCCE
MLFVLGEYVAIVTMCAMGTILFLGGWLPPVPYAPFTWVPGIVWFALKVLFMFFMFAMAKA
EHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IVPRYRYDQLMRLGWKVFLPLSLAMVVIVAAVLQFAGLAPK
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
ADFFMTNLWPLIVVIGQSVLLIVVLLISIAYILLADRKIWAAVQIRRGPNVVGPWGLLQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCCCCCCHHHHHH
SFADLLKMILKEPMIPSGANKGVFLLAPLVTCVLALSAWAVIPVSAGWVIADINVGVLYI
HHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHEEECCCEEEEECCHHHHHH
LAVSSLSVYGIIMAGWSSNSKYPFLAALRSAAQMVSYEVSIGFVIICVLLCVGSLNLTAI
HHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
VQAQNSQWGVLGWYWLPLFPMFVVFYVSALAETNRPPFDLVEAESELVAGFMVEYSSTPY
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEECCCCE
MLFVLGEYVAIVTMCAMGTILFLGGWLPPVPYAPFTWVPGIVWFALKVLFMFFMFAMAKA
EHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IVPRYRYDQLMRLGWKVFLPLSLAMVVIVAAVLQFAGLAPK
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA