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The map label for this gene is nqo3 [H]

Identifier: 86749698

GI number: 86749698

Start: 2960644

End: 2962719

Strand: Direct

Name: nqo3 [H]

Synonym: RPB_2580

Alternate gene names: 86749698

Gene position: 2960644-2962719 (Clockwise)

Preceding gene: 86749697

Following gene: 86749699

Centisome position: 55.53

GC content: 68.79

Gene sequence:

>2076_bases
ATGATCAAGATCATCGTCGACGGCAAGGAAGTCGAGGTTCCGCCGGAATACACGCTGCTGCAGGCCTGTGAGTCGGCCGG
CGCGGAGATTCCGCGGTTCTGTTATCACGAGCGACTGTCGATCGCCGGCAATTGCCGGATGTGTCTGGTCGAGCTGAAAG
GCACGCCGAAGCCGGTGGCGAGCTGCGCCTGGGGCGTGCGCGATTGCCGGCCGGGTCCGAACGGCGAGCCGCCGGAGATC
AACACCAAATCGCCGATGGTGAAGAAGGCCCGCGAGGGCGTGATGGAGTTCCTGCTGATCAACCATCCGCTCGACTGCCC
GATCTGCGATCAGGGCGGCGAGTGCGACCTGCAGGACCAGGCGATGGGCTACGGCGTCGACACCAGCCGGTTCGCCGAGA
ACAAGCGCGCGGTCGAGGACAAGTATCTCGGCGTGCTGGTCAAGACCTCGATGACCCGCTGCATCCAGTGCACCCGCTGC
GTTCGCTTCGCCGCCGAAGTCTGCGGCGTGCCGGAGATGGGCGCGACCGGCCGCGGCGAGGACATGGAGATCACCACCTA
TCTCGAGAGCGCGCTGACATCGGAGCTGCAGGGCAATCTGGTCGACATCTGCCCGGTGGGCGCGCTGACCTCGAAGCCTT
ATGCGTTTGCCGCGCGGCCCTGGGAACTCGGCAAGACGCAGTCGGTCGACGTCATGGACGGCGTCGGCTCGGCGATCCGG
GTCGATACCCGCGGCCGTGAGGTGATGCGGATCCTGCCGCGCGTCAACGAGGCGATCAACGAGGAGTGGATCTCCGACAA
GACCCGCCACGTCGTCGACGGGTTGCGCACCCAGCGGCTCGACCGGCCCTATGTCCGCGACGGCGGCAAGCTGCGCCCGG
CGAGCTGGCCGGAAGCGTTCGCCGCGATCAAGGCCAAGCTCGCCGGCGTCGGCGGCAAGAAGATCGGCGCGATCGCCGGC
GATCTCGCCGCGGTCGAGGAGATGTTCGCGCTGAAGCAATTGCTGGCGGCGCTCGGCTCGTCGAACCTGGCTGCGCAGAA
CGTCGCCGCGTTCGATCCGAAAGCGGGGCGGGCGTCGTACATCTTCAATCCGACCATCGCCGGCCTCGAGCAGGCCGATG
CATTGCTGATCATCGGCTCCAACCCGCGCAAGGAAGCGGCGATCCTCAACGCCCGTATCCGCAAGCGCTGGCGCGCCAGC
GGCCTGCCGATCGGCGTGATCGGCGAGCAGGCCGATCTGACCTATCCGACCGAGTATCTCGGCGCCGGCGCAGAGACGCT
GGCGGACCTTGCCTCCGGCAAGCATTCCTTCGCCGAGAAGCTGAAGGCCGCGAAGAACCCGATCGTGCTGGTCGGCGCGG
CTGCGACCTCGCGCCGCGACGGCGCGGCTCTGCTGGCGGCGGCGGCCAAGCTCGCGGTCGATATCGGCGCGCTCGCCGAC
GGCTGGAACGGCTTTGCGGTGCTGCATCCGGCGGCGTCCAGCGTCGGTGCGCTGGACATCGGCTTCGTGCCGGGCGCCGG
CGGCATCGACGCCGCGCAGATGACCACCGCCGGTGCGCTGGACGTGGTGTTCGCGCTCGGCGCAGACGAGGTGAAGCTGC
CGGACGGCGCGTTCGTGGTCTATATCGGCACCCATGGCGACCGCGGCGCGCATCGCGCCGACGTCATCCTGCCGGGCGCG
GCGTACACCGAGAAGTCGGGCATCTACGTCAACACCGAAGGCCGGGTGCAGATCGCCAATCGGGCGGCGTTTCCGCCAGG
CGACGCGCGCGAGGACTGGGCGATCATCCGTGCGCTGTCCGAGGCGCTGGGCCACAAGCTGCCGTTCGATTCGCTGGCCA
GCTTGCGCAAGGCGATCTTCGCCGCGGTGCCGCATCTGATGCGGGTCGACCAGATCGAGGCCGGCGACGCCGGTGCGGTG
CGCGCGCTCGCCGCGTCCGGCGGCAGCGTCGACAAGGCACCGATCAAGCCGGCGATCGCCGATTTCTACATGACCAACCC
GATCGCGCGGGCGTCCGCCGTGATGGCGGAGTGCTCCCGCCTGGCGTCGGGGCAGATGCTGACGGCGGCGGAGTAG

Upstream 100 bases:

>100_bases
CCGAGATCGAGCGCCGCATCGACGATTTCTCGCGCAAGGCCACGCTCGACGATCAGGGCGTGCTCGATCCGGCGCATATG
GTGGCGGCGGAGTAACAGCC

Downstream 100 bases:

>100_bases
GCGAGGCCCATGGCTGATTTCTTCATGACCAACCTGTGGCCGCTGATCGTCGTGATCGGGCAGAGCGTGCTGCTGATCGT
GGTGCTGCTGATCTCGATCG

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I, chain 3; NDH-1, chain 3 [H]

Number of amino acids: Translated: 691; Mature: 691

Protein sequence:

>691_residues
MIKIIVDGKEVEVPPEYTLLQACESAGAEIPRFCYHERLSIAGNCRMCLVELKGTPKPVASCAWGVRDCRPGPNGEPPEI
NTKSPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQAMGYGVDTSRFAENKRAVEDKYLGVLVKTSMTRCIQCTRC
VRFAAEVCGVPEMGATGRGEDMEITTYLESALTSELQGNLVDICPVGALTSKPYAFAARPWELGKTQSVDVMDGVGSAIR
VDTRGREVMRILPRVNEAINEEWISDKTRHVVDGLRTQRLDRPYVRDGGKLRPASWPEAFAAIKAKLAGVGGKKIGAIAG
DLAAVEEMFALKQLLAALGSSNLAAQNVAAFDPKAGRASYIFNPTIAGLEQADALLIIGSNPRKEAAILNARIRKRWRAS
GLPIGVIGEQADLTYPTEYLGAGAETLADLASGKHSFAEKLKAAKNPIVLVGAAATSRRDGAALLAAAAKLAVDIGALAD
GWNGFAVLHPAASSVGALDIGFVPGAGGIDAAQMTTAGALDVVFALGADEVKLPDGAFVVYIGTHGDRGAHRADVILPGA
AYTEKSGIYVNTEGRVQIANRAAFPPGDAREDWAIIRALSEALGHKLPFDSLASLRKAIFAAVPHLMRVDQIEAGDAGAV
RALAASGGSVDKAPIKPAIADFYMTNPIARASAVMAECSRLASGQMLTAAE

Sequences:

>Translated_691_residues
MIKIIVDGKEVEVPPEYTLLQACESAGAEIPRFCYHERLSIAGNCRMCLVELKGTPKPVASCAWGVRDCRPGPNGEPPEI
NTKSPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQAMGYGVDTSRFAENKRAVEDKYLGVLVKTSMTRCIQCTRC
VRFAAEVCGVPEMGATGRGEDMEITTYLESALTSELQGNLVDICPVGALTSKPYAFAARPWELGKTQSVDVMDGVGSAIR
VDTRGREVMRILPRVNEAINEEWISDKTRHVVDGLRTQRLDRPYVRDGGKLRPASWPEAFAAIKAKLAGVGGKKIGAIAG
DLAAVEEMFALKQLLAALGSSNLAAQNVAAFDPKAGRASYIFNPTIAGLEQADALLIIGSNPRKEAAILNARIRKRWRAS
GLPIGVIGEQADLTYPTEYLGAGAETLADLASGKHSFAEKLKAAKNPIVLVGAAATSRRDGAALLAAAAKLAVDIGALAD
GWNGFAVLHPAASSVGALDIGFVPGAGGIDAAQMTTAGALDVVFALGADEVKLPDGAFVVYIGTHGDRGAHRADVILPGA
AYTEKSGIYVNTEGRVQIANRAAFPPGDAREDWAIIRALSEALGHKLPFDSLASLRKAIFAAVPHLMRVDQIEAGDAGAV
RALAASGGSVDKAPIKPAIADFYMTNPIARASAVMAECSRLASGQMLTAAE
>Mature_691_residues
MIKIIVDGKEVEVPPEYTLLQACESAGAEIPRFCYHERLSIAGNCRMCLVELKGTPKPVASCAWGVRDCRPGPNGEPPEI
NTKSPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQAMGYGVDTSRFAENKRAVEDKYLGVLVKTSMTRCIQCTRC
VRFAAEVCGVPEMGATGRGEDMEITTYLESALTSELQGNLVDICPVGALTSKPYAFAARPWELGKTQSVDVMDGVGSAIR
VDTRGREVMRILPRVNEAINEEWISDKTRHVVDGLRTQRLDRPYVRDGGKLRPASWPEAFAAIKAKLAGVGGKKIGAIAG
DLAAVEEMFALKQLLAALGSSNLAAQNVAAFDPKAGRASYIFNPTIAGLEQADALLIIGSNPRKEAAILNARIRKRWRAS
GLPIGVIGEQADLTYPTEYLGAGAETLADLASGKHSFAEKLKAAKNPIVLVGAAATSRRDGAALLAAAAKLAVDIGALAD
GWNGFAVLHPAASSVGALDIGFVPGAGGIDAAQMTTAGALDVVFALGADEVKLPDGAFVVYIGTHGDRGAHRADVILPGA
AYTEKSGIYVNTEGRVQIANRAAFPPGDAREDWAIIRALSEALGHKLPFDSLASLRKAIFAAVPHLMRVDQIEAGDAGAV
RALAASGGSVDKAPIKPAIADFYMTNPIARASAVMAECSRLASGQMLTAAE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=699, Percent_Identity=53.0758226037196, Blast_Score=703, Evalue=0.0,
Organism=Escherichia coli, GI145693161, Length=712, Percent_Identity=26.123595505618, Blast_Score=187, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17565758, Length=699, Percent_Identity=50.071530758226, Blast_Score=652, Evalue=0.0,
Organism=Caenorhabditis elegans, GI32566231, Length=591, Percent_Identity=51.7766497461929, Blast_Score=582, Evalue=1e-166,
Organism=Caenorhabditis elegans, GI193209088, Length=261, Percent_Identity=60.9195402298851, Blast_Score=337, Evalue=2e-92,
Organism=Drosophila melanogaster, GI24640559, Length=691, Percent_Identity=51.8089725036179, Blast_Score=667, Evalue=0.0,
Organism=Drosophila melanogaster, GI24640557, Length=691, Percent_Identity=51.8089725036179, Blast_Score=667, Evalue=0.0,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 72938; Mature: 72938

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKIIVDGKEVEVPPEYTLLQACESAGAEIPRFCYHERLSIAGNCRMCLVELKGTPKPVA
CEEEEECCCEECCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCHHH
SCAWGVRDCRPGPNGEPPEINTKSPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQ
HHHCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHH
AMGYGVDTSRFAENKRAVEDKYLGVLVKTSMTRCIQCTRCVRFAAEVCGVPEMGATGRGE
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
DMEITTYLESALTSELQGNLVDICPVGALTSKPYAFAARPWELGKTQSVDVMDGVGSAIR
CCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCCHHHHCCCCEEE
VDTRGREVMRILPRVNEAINEEWISDKTRHVVDGLRTQRLDRPYVRDGGKLRPASWPEAF
ECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCHHHH
AAIKAKLAGVGGKKIGAIAGDLAAVEEMFALKQLLAALGSSNLAAQNVAAFDPKAGRASY
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEE
IFNPTIAGLEQADALLIIGSNPRKEAAILNARIRKRWRASGLPIGVIGEQADLTYPTEYL
EECCCHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHH
GAGAETLADLASGKHSFAEKLKAAKNPIVLVGAAATSRRDGAALLAAAAKLAVDIGALAD
CCCHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCC
GWNGFAVLHPAASSVGALDIGFVPGAGGIDAAQMTTAGALDVVFALGADEVKLPDGAFVV
CCCCEEEEECCCCCCCEEEEECCCCCCCCCHHHHHHCCHHHHHEECCCCCEECCCCCEEE
YIGTHGDRGAHRADVILPGAAYTEKSGIYVNTEGRVQIANRAAFPPGDAREDWAIIRALS
EEECCCCCCCCCCCEEECCCCEECCCCEEEECCCCEEECCCCCCCCCCCCHHHHHHHHHH
EALGHKLPFDSLASLRKAIFAAVPHLMRVDQIEAGDAGAVRALAASGGSVDKAPIKPAIA
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHH
DFYMTNPIARASAVMAECSRLASGQMLTAAE
HHHHCCCHHHHHHHHHHHHHHHCCCEEECCC
>Mature Secondary Structure
MIKIIVDGKEVEVPPEYTLLQACESAGAEIPRFCYHERLSIAGNCRMCLVELKGTPKPVA
CEEEEECCCEECCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCHHH
SCAWGVRDCRPGPNGEPPEINTKSPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQ
HHHCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHH
AMGYGVDTSRFAENKRAVEDKYLGVLVKTSMTRCIQCTRCVRFAAEVCGVPEMGATGRGE
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
DMEITTYLESALTSELQGNLVDICPVGALTSKPYAFAARPWELGKTQSVDVMDGVGSAIR
CCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCCHHHHCCCCEEE
VDTRGREVMRILPRVNEAINEEWISDKTRHVVDGLRTQRLDRPYVRDGGKLRPASWPEAF
ECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCHHHH
AAIKAKLAGVGGKKIGAIAGDLAAVEEMFALKQLLAALGSSNLAAQNVAAFDPKAGRASY
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEE
IFNPTIAGLEQADALLIIGSNPRKEAAILNARIRKRWRASGLPIGVIGEQADLTYPTEYL
EECCCHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHH
GAGAETLADLASGKHSFAEKLKAAKNPIVLVGAAATSRRDGAALLAAAAKLAVDIGALAD
CCCHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCC
GWNGFAVLHPAASSVGALDIGFVPGAGGIDAAQMTTAGALDVVFALGADEVKLPDGAFVV
CCCCEEEEECCCCCCCEEEEECCCCCCCCCHHHHHHCCHHHHHEECCCCCEECCCCCEEE
YIGTHGDRGAHRADVILPGAAYTEKSGIYVNTEGRVQIANRAAFPPGDAREDWAIIRALS
EEECCCCCCCCCCCEEECCCCEECCCCEEEECCCCEEECCCCCCCCCCCCHHHHHHHHHH
EALGHKLPFDSLASLRKAIFAAVPHLMRVDQIEAGDAGAVRALAASGGSVDKAPIKPAIA
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHH
DFYMTNPIARASAVMAECSRLASGQMLTAAE
HHHHCCCHHHHHHHHHHHHHHHCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1605643; 8422400 [H]