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The map label for this gene is vhb [H]

Identifier: 86748879

GI number: 86748879

Start: 2010261

End: 2010680

Strand: Reverse

Name: vhb [H]

Synonym: RPB_1756

Alternate gene names: 86748879

Gene position: 2010680-2010261 (Counterclockwise)

Preceding gene: 86748880

Following gene: 86748878

Centisome position: 37.71

GC content: 68.57

Gene sequence:

>420_bases
ATGACCCCCGCACAGATCGCCCTGGTTCAGCAGAGCTTCGCCAAGGTCGCACCGATTTCCGAACAGGCGGCGAGCCTGTT
CTATGGCCGGCTGTTCGAGATCGCGCCCGAGGTGCAGCCGCTGTTCGCCAAGGCGGACATCCGCGACCAGGGTAAGAAGC
TGATGGGCACGCTCGCGGTGGTGGTCGGCGGGCTGACCGATCTGCCGGCGATCCTGCCGGCGGCGAGCCGGCTCGCCAAA
CTGCATGTCAGTTACGGCGTGCAGCCCACGCACTACGCGCCGGTCGGCGCCGCGCTGCTGTGGACGCTCGAACAGGGGCT
GGGCGGAGCCTGGACGCCCGACCTCGCCGAGGCGTGGACCGCGGCCTACGCAACGCTGTCGAACTACATGATCGCGGAAG
CCTATGGCGTGGCGGCGTGA

Upstream 100 bases:

>100_bases
GCCGCCTACGCCTGACGTGCCTCGCGCACGTCGCGGGACGTGAACCGATCGCGGCCCGCAAAGACATACGACCTCCCCTC
ACGCAGCAAGGAGAGGTCCG

Downstream 100 bases:

>100_bases
TGAGGAAGTCAGCGCGCGATACGGCACGCACCCCTTCCCTCTCCCCTTGTGGGAGAGGGTGCCTGAGACGCGCAGCGTCG
AAGGCGGGTGAGGGGTCGCG

Product: globin

Products: @TETR01txt*tetrahydropteridine!; NO3-; NAD(P); Proton [C]

Alternate protein names: Soluble cytochrome O [H]

Number of amino acids: Translated: 139; Mature: 138

Protein sequence:

>139_residues
MTPAQIALVQQSFAKVAPISEQAASLFYGRLFEIAPEVQPLFAKADIRDQGKKLMGTLAVVVGGLTDLPAILPAASRLAK
LHVSYGVQPTHYAPVGAALLWTLEQGLGGAWTPDLAEAWTAAYATLSNYMIAEAYGVAA

Sequences:

>Translated_139_residues
MTPAQIALVQQSFAKVAPISEQAASLFYGRLFEIAPEVQPLFAKADIRDQGKKLMGTLAVVVGGLTDLPAILPAASRLAK
LHVSYGVQPTHYAPVGAALLWTLEQGLGGAWTPDLAEAWTAAYATLSNYMIAEAYGVAA
>Mature_138_residues
TPAQIALVQQSFAKVAPISEQAASLFYGRLFEIAPEVQPLFAKADIRDQGKKLMGTLAVVVGGLTDLPAILPAASRLAKL
HVSYGVQPTHYAPVGAALLWTLEQGLGGAWTPDLAEAWTAAYATLSNYMIAEAYGVAA

Specific function: This protein functions as a terminal oxidase [H]

COG id: COG1017

COG function: function code C; Hemoglobin-like flavoprotein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the globin family [H]

Homologues:

Organism=Escherichia coli, GI1788903, Length=141, Percent_Identity=31.2056737588652, Blast_Score=71, Evalue=3e-14,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971 [H]

Pfam domain/function: PF00042 Globin [H]

EC number: 1.5.1.34 [C]

Molecular weight: Translated: 14642; Mature: 14511

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS01033 GLOBIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPAQIALVQQSFAKVAPISEQAASLFYGRLFEIAPEVQPLFAKADIRDQGKKLMGTLAV
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHH
VVGGLTDLPAILPAASRLAKLHVSYGVQPTHYAPVGAALLWTLEQGLGGAWTPDLAEAWT
HHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHH
AAYATLSNYMIAEAYGVAA
HHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TPAQIALVQQSFAKVAPISEQAASLFYGRLFEIAPEVQPLFAKADIRDQGKKLMGTLAV
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHH
VVGGLTDLPAILPAASRLAKLHVSYGVQPTHYAPVGAALLWTLEQGLGGAWTPDLAEAWT
HHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHH
AAYATLSNYMIAEAYGVAA
HHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: FAD [C]

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dihydropteridine; 2 nitric oxide; O2; NAD(P)H [C]

Specific reaction: NAD(P)H + dihydropteridine = NAD(P)+ @TETR01.txt*tetrahydropteridine! 2 nitric oxide + 2 O2 + NAD(P)H = 2 NO3- + NAD(P) + Proton [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3067078; 3736670; 2685332; 2681149; 9115439 [H]