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The map label for this gene is hmp [C]

Identifier: 86748880

GI number: 86748880

Start: 2010766

End: 2011224

Strand: Reverse

Name: hmp [C]

Synonym: RPB_1757

Alternate gene names: 86748880

Gene position: 2011224-2010766 (Counterclockwise)

Preceding gene: 86748881

Following gene: 86748879

Centisome position: 37.72

GC content: 63.83

Gene sequence:

>459_bases
ATGCGTCCCCGCATTTCCGGATTACTGCGCGCCATGTCTCGCTCACACGGTCTTTCGCCGGCGGAAGTCGCCGAGATTCA
GAACTCGTTCGACCGGATGTGGCCGCGGTCGAACGTGATGGTCGACCTGTTCTACGACCGGTTGTTCGAACTGGTGCCGG
ACTCGCGGCCGCTGTTTCGCGACGACATGGCGAACCTCAAGCGCAAGTTCATCTCGACCCTCGCGGTGATCGTCGGCAGT
CTCGACAATCTCTCCGGGCTGTTGTCGGTCGCCGACAAGCTCGCCAGGGATCACGTGCACTACGGCGTGACAGCGTCGCA
TTATGCGCCGGTCGGCGAGGCGCTGCTGTGGAGCATGCGCGAAGGTCTCGGCACGCACTGGACGCCGGCCGTCGAGGACG
CCTGGACCAAGCTGTACGTGTTTCTGTCCGGCCGGATGATCGCTGCCGCCTACGCCTGA

Upstream 100 bases:

>100_bases
GTGCTCGAATTCCTCTACGAGCGTCATCGCTACATCGAGGCCGCTTAGCACGCTCGATGACAAATCGATGACACTTGACA
TTCGAGGGCAAATCGCATGA

Downstream 100 bases:

>100_bases
CGTGCCTCGCGCACGTCGCGGGACGTGAACCGATCGCGGCCCGCAAAGACATACGACCTCCCCTCACGCAGCAAGGAGAG
GTCCGATGACCCCCGCACAG

Product: globin

Products: @TETR01txt*tetrahydropteridine!; NO3-; NAD(P); Proton [C]

Alternate protein names: Flavohemoprotein; Hemoglobin; Globin Domain Protein; Nitric Oxide Dioxygenase; Protein Kinase; Globin Domain-Containing Protein; Hemoprotein; Globin-Like Protein; Oxidoreductase; 2-Polyprenylphenol Hydroxylase-Like Protein; Globin-Coupled Methyl-Accepting Chemotaxis Protein; Hemoglobin-Like Flavoprotein; Flavohemoglobin; 2-Polyprenylphenol Hydroxylase-Like Oxidoreductase; Flavohemoglobin / Bacterial Hemoglobin; Hemoglobin-Like Protein; Hemoglobin-Like Flavo Domain; Bacterial Hemoglobin; Methyl-Accepting Chemotaxis Sensory Transducer

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MRPRISGLLRAMSRSHGLSPAEVAEIQNSFDRMWPRSNVMVDLFYDRLFELVPDSRPLFRDDMANLKRKFISTLAVIVGS
LDNLSGLLSVADKLARDHVHYGVTASHYAPVGEALLWSMREGLGTHWTPAVEDAWTKLYVFLSGRMIAAAYA

Sequences:

>Translated_152_residues
MRPRISGLLRAMSRSHGLSPAEVAEIQNSFDRMWPRSNVMVDLFYDRLFELVPDSRPLFRDDMANLKRKFISTLAVIVGS
LDNLSGLLSVADKLARDHVHYGVTASHYAPVGEALLWSMREGLGTHWTPAVEDAWTKLYVFLSGRMIAAAYA
>Mature_152_residues
MRPRISGLLRAMSRSHGLSPAEVAEIQNSFDRMWPRSNVMVDLFYDRLFELVPDSRPLFRDDMANLKRKFISTLAVIVGS
LDNLSGLLSVADKLARDHVHYGVTASHYAPVGEALLWSMREGLGTHWTPAVEDAWTKLYVFLSGRMIAAAYA

Specific function: Possesses Dihydropteridine Reductase Activity. Also Has Nitric Oxide Dioxygenase Activity. Seems To Reduces The Complexed Fe(3+) Iron Of Siderophores To Fe(2+), Thus Releasing It From The Chelator. [C]

COG id: COG1017

COG function: function code C; Hemoglobin-like flavoprotein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.5.1.34 [C]

Molecular weight: Translated: 17080; Mature: 17080

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: PS01033 GLOBIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPRISGLLRAMSRSHGLSPAEVAEIQNSFDRMWPRSNVMVDLFYDRLFELVPDSRPLFR
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHH
DDMANLKRKFISTLAVIVGSLDNLSGLLSVADKLARDHVHYGVTASHYAPVGEALLWSMR
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCHHHHHHHHHHH
EGLGTHWTPAVEDAWTKLYVFLSGRMIAAAYA
HCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCC
>Mature Secondary Structure
MRPRISGLLRAMSRSHGLSPAEVAEIQNSFDRMWPRSNVMVDLFYDRLFELVPDSRPLFR
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHH
DDMANLKRKFISTLAVIVGSLDNLSGLLSVADKLARDHVHYGVTASHYAPVGEALLWSMR
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCHHHHHHHHHHH
EGLGTHWTPAVEDAWTKLYVFLSGRMIAAAYA
HCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: FAD [C]

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dihydropteridine; 2 nitric oxide; O2; NAD(P)H [C]

Specific reaction: NAD(P)H + dihydropteridine = NAD(P)+ @TETR01.txt*tetrahydropteridine! 2 nitric oxide + 2 O2 + NAD(P)H = 2 NO3- + NAD(P) + Proton [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA