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The map label for this gene is yisK [H]

Identifier: 86748827

GI number: 86748827

Start: 1939198

End: 1940070

Strand: Reverse

Name: yisK [H]

Synonym: RPB_1704

Alternate gene names: 86748827

Gene position: 1940070-1939198 (Counterclockwise)

Preceding gene: 86748828

Following gene: 86748826

Centisome position: 36.39

GC content: 65.06

Gene sequence:

>873_bases
ATGACCACTCCTCGCCTCGCCACCTTCACCGTCAACGGCCTCACCCGCTATGGCGCGGTGTGCGATCATGGGGTGGTCGA
TCTGTCGGCCCGCCATGCCAACGATTATCCGACGCTGCGCGAGGTGATCGCCGCCGGTGCGCTCCAGCGGATCGTCGACG
AGGCCGACCACACCGCGCCCGATTTCGCCCGCGACAAGGTCGTGTTTCAGCCGCCGATTCCGCAGCCCGAAAAGATCATC
TGCGTCGGCGTCAACTATCCCGAGCGCAACGCCGAATACAAAGACAACACCGAGGCGCCGAAATTCCCGAGCATGTTCAT
GCGCACGGCCCGCTCTTTCGTCGGCCACGGCGCCTCGCTGGTGCGGCCGAAAGCGTCGAAGCTGCTCGACTATGAGGGCG
AGCTGACGCTGGTGATCGGCAAGCCCGGCCGCCACATCGCGGAAGCCGATGCGCTCGACCATGTCGCCGCGATCACGCTG
TGCAACGAAGGCACGATCCGCGACTGGGTGCGTCATGCCAAGTTCAACGTCACGCAGGGCAAGAATTTCGATCACACCGG
CGGCCTCGGCCCGTGGATCCTGCCGTTCACGGACGAAGCGCAAATCGCCGACATCCGTCTCACCACCCGCGTCAACGGCG
ATATCCGGCAGGACGACCGCACCTCCCGGATGATCTTCGGCTTCCGCTATCTGATTCACTACATCTCGACCTTCACCACG
CTGGTGCCGGGCGATCTGATCATCACCGGCACGCCGGCCGGCGCCGGCGCACGCTCCGACCCGCCGGTGTACTTGAAGCC
CGGCGATATCATCGAGGTCGAGGCCGACGGCATCGGCGTGCTCCGCAATGGCGTCGTCGACGAAGCCGACTAG

Upstream 100 bases:

>100_bases
AGCCAGTATGGCAGAGCGCTGGTTCGAACCATGACCGCTCTGGAATACTGGGTCACCCGCTGTCGCGGGTGATGACGCCT
CGATCAAAAGGAAAGCCGCT

Downstream 100 bases:

>100_bases
CTCCAATCCAACAACGAGACCCAAAATGAGCATCATGACCGGCGGCGAAGCGATCGTGCAGACCCTCGTCGCGCACGGCG
TCGACACCGTGTTCGGCCTG

Product: 5-carboxymethyl-2-hydroxymuconate delta-isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MTTPRLATFTVNGLTRYGAVCDHGVVDLSARHANDYPTLREVIAAGALQRIVDEADHTAPDFARDKVVFQPPIPQPEKII
CVGVNYPERNAEYKDNTEAPKFPSMFMRTARSFVGHGASLVRPKASKLLDYEGELTLVIGKPGRHIAEADALDHVAAITL
CNEGTIRDWVRHAKFNVTQGKNFDHTGGLGPWILPFTDEAQIADIRLTTRVNGDIRQDDRTSRMIFGFRYLIHYISTFTT
LVPGDLIITGTPAGAGARSDPPVYLKPGDIIEVEADGIGVLRNGVVDEAD

Sequences:

>Translated_290_residues
MTTPRLATFTVNGLTRYGAVCDHGVVDLSARHANDYPTLREVIAAGALQRIVDEADHTAPDFARDKVVFQPPIPQPEKII
CVGVNYPERNAEYKDNTEAPKFPSMFMRTARSFVGHGASLVRPKASKLLDYEGELTLVIGKPGRHIAEADALDHVAAITL
CNEGTIRDWVRHAKFNVTQGKNFDHTGGLGPWILPFTDEAQIADIRLTTRVNGDIRQDDRTSRMIFGFRYLIHYISTFTT
LVPGDLIITGTPAGAGARSDPPVYLKPGDIIEVEADGIGVLRNGVVDEAD
>Mature_289_residues
TTPRLATFTVNGLTRYGAVCDHGVVDLSARHANDYPTLREVIAAGALQRIVDEADHTAPDFARDKVVFQPPIPQPEKIIC
VGVNYPERNAEYKDNTEAPKFPSMFMRTARSFVGHGASLVRPKASKLLDYEGELTLVIGKPGRHIAEADALDHVAAITLC
NEGTIRDWVRHAKFNVTQGKNFDHTGGLGPWILPFTDEAQIADIRLTTRVNGDIRQDDRTSRMIFGFRYLIHYISTFTTL
VPGDLIITGTPAGAGARSDPPVYLKPGDIIEVEADGIGVLRNGVVDEAD

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=266, Percent_Identity=36.8421052631579, Blast_Score=169, Evalue=2e-42,
Organism=Homo sapiens, GI40786394, Length=266, Percent_Identity=36.4661654135338, Blast_Score=167, Evalue=9e-42,
Organism=Homo sapiens, GI66348062, Length=215, Percent_Identity=33.953488372093, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI215422413, Length=186, Percent_Identity=33.3333333333333, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI13654274, Length=186, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=1e-22,
Organism=Escherichia coli, GI1787428, Length=205, Percent_Identity=30.2439024390244, Blast_Score=76, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17557057, Length=198, Percent_Identity=34.8484848484849, Blast_Score=107, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6324161, Length=231, Percent_Identity=29.8701298701299, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28572127, Length=240, Percent_Identity=33.3333333333333, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24663695, Length=219, Percent_Identity=36.5296803652968, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI28571789, Length=204, Percent_Identity=34.3137254901961, Blast_Score=104, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 31775; Mature: 31644

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPRLATFTVNGLTRYGAVCDHGVVDLSARHANDYPTLREVIAAGALQRIVDEADHTAP
CCCCCEEEEEECCHHHHCCHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
DFARDKVVFQPPIPQPEKIICVGVNYPERNAEYKDNTEAPKFPSMFMRTARSFVGHGASL
CHHCCCEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHH
VRPKASKLLDYEGELTLVIGKPGRHIAEADALDHVAAITLCNEGTIRDWVRHAKFNVTQG
CCCCHHHHCCCCCCEEEEECCCCCCHHHHHHHHHEEEEEEECCCCHHHHHHHHEECCCCC
KNFDHTGGLGPWILPFTDEAQIADIRLTTRVNGDIRQDDRTSRMIFGFRYLIHYISTFTT
CCCCCCCCCCCEEEECCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LVPGDLIITGTPAGAGARSDPPVYLKPGDIIEVEADGIGVLRNGVVDEAD
HCCCCEEEECCCCCCCCCCCCCEEECCCCEEEEECCCCEEHHCCCCCCCC
>Mature Secondary Structure 
TTPRLATFTVNGLTRYGAVCDHGVVDLSARHANDYPTLREVIAAGALQRIVDEADHTAP
CCCCEEEEEECCHHHHCCHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
DFARDKVVFQPPIPQPEKIICVGVNYPERNAEYKDNTEAPKFPSMFMRTARSFVGHGASL
CHHCCCEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHH
VRPKASKLLDYEGELTLVIGKPGRHIAEADALDHVAAITLCNEGTIRDWVRHAKFNVTQG
CCCCHHHHCCCCCCEEEEECCCCCCHHHHHHHHHEEEEEEECCCCHHHHHHHHEECCCCC
KNFDHTGGLGPWILPFTDEAQIADIRLTTRVNGDIRQDDRTSRMIFGFRYLIHYISTFTT
CCCCCCCCCCCEEEECCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LVPGDLIITGTPAGAGARSDPPVYLKPGDIIEVEADGIGVLRNGVVDEAD
HCCCCEEEECCCCCCCCCCCCCEEECCCCEEEEECCCCEEHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9384377 [H]