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The map label for this gene is gmhB1 [H]

Identifier: 86748724

GI number: 86748724

Start: 1802799

End: 1803350

Strand: Reverse

Name: gmhB1 [H]

Synonym: RPB_1599

Alternate gene names: 86748724

Gene position: 1803350-1802799 (Counterclockwise)

Preceding gene: 86748725

Following gene: 86748722

Centisome position: 33.82

GC content: 64.67

Gene sequence:

>552_bases
ATGACGGCGAGCGCCACCACGCCGCTGCGTCCCGCCGCGTTTCTCGATCGCGACGGCGTCGTGAACTACAATGATCACTA
TATCGGCAGCCGCGACCGGTTTCGCTGGATGCCGGGGATCGCATCGGCGATCCGCCGTCTCAACCAAGCCGGCTACTACG
TCTTCGTCATTACTAACCAGTCCGGCGTCGCCCGCGGCCTATTCAGCGAGGACGACGTCCAGGCGCTGCATCGCTGGATG
CTGGACGAACTCCGCGAGCAGAACGCGCGGATCGACGACATCCGCTACTGCCCGCATCATCCCGACGGCATCGTCGAGGC
GTATCGCCGGGCGAGCGACGACCGCAAGCCGAAGCCCGGCATGATCCTCGATCTCGCGCGCGCCTGGCCGGTGTCGCTGC
AGGGCAGTTTCGTGATCGGCGACAGCGACAGCGATATCGAAGCCGCAACGGCGGCGGGTATTCAGGGCTTTCTGTTCGAG
GGCGACGATATCGACGCGTTCGTCTCAAAGGTCCTCGACACGATGGCGCGCAGCGACGCAGCGCAGAACTAA

Upstream 100 bases:

>100_bases
TGGTGGCGCCGGGCGCCGAAACCGCTCTGGTGCAACAGATCCATCTGGTGGCCGCGCACGCGATCTGCGACGAGATCGAA
GGCGCGCTGGCAGCCGGGGC

Downstream 100 bases:

>100_bases
TCGAGCAGCCGTTCGGCGGCCTCGATCGCCTGCCGCGCAGAGGGCGCGCCGCTCTTGCCGCCCAATACGCGCATCGGACC
GCTGCCGACCGGGCCGGTCA

Product: histidinol-phosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase 1 [H]

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MTASATTPLRPAAFLDRDGVVNYNDHYIGSRDRFRWMPGIASAIRRLNQAGYYVFVITNQSGVARGLFSEDDVQALHRWM
LDELREQNARIDDIRYCPHHPDGIVEAYRRASDDRKPKPGMILDLARAWPVSLQGSFVIGDSDSDIEAATAAGIQGFLFE
GDDIDAFVSKVLDTMARSDAAQN

Sequences:

>Translated_183_residues
MTASATTPLRPAAFLDRDGVVNYNDHYIGSRDRFRWMPGIASAIRRLNQAGYYVFVITNQSGVARGLFSEDDVQALHRWM
LDELREQNARIDDIRYCPHHPDGIVEAYRRASDDRKPKPGMILDLARAWPVSLQGSFVIGDSDSDIEAATAAGIQGFLFE
GDDIDAFVSKVLDTMARSDAAQN
>Mature_182_residues
TASATTPLRPAAFLDRDGVVNYNDHYIGSRDRFRWMPGIASAIRRLNQAGYYVFVITNQSGVARGLFSEDDVQALHRWML
DELREQNARIDDIRYCPHHPDGIVEAYRRASDDRKPKPGMILDLARAWPVSLQGSFVIGDSDSDIEAATAAGIQGFLFEG
DDIDAFVSKVLDTMARSDAAQN

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=144, Percent_Identity=41.6666666666667, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI87082027, Length=155, Percent_Identity=28.3870967741935, Blast_Score=75, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: 3.1.1.-

Molecular weight: Translated: 20394; Mature: 20263

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASATTPLRPAAFLDRDGVVNYNDHYIGSRDRFRWMPGIASAIRRLNQAGYYVFVITNQ
CCCCCCCCCCCHHHCCCCCEECCCCCCCCCCCCCEECHHHHHHHHHHHHCCEEEEEEECC
SGVARGLFSEDDVQALHRWMLDELREQNARIDDIRYCPHHPDGIVEAYRRASDDRKPKPG
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHCCCCCCCCC
MILDLARAWPVSLQGSFVIGDSDSDIEAATAAGIQGFLFEGDDIDAFVSKVLDTMARSDA
CEEECCCCCCCCCCCCEEECCCCCCCHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHCC
AQN
CCC
>Mature Secondary Structure 
TASATTPLRPAAFLDRDGVVNYNDHYIGSRDRFRWMPGIASAIRRLNQAGYYVFVITNQ
CCCCCCCCCCHHHCCCCCEECCCCCCCCCCCCCEECHHHHHHHHHHHHCCEEEEEEECC
SGVARGLFSEDDVQALHRWMLDELREQNARIDDIRYCPHHPDGIVEAYRRASDDRKPKPG
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHCCCCCCCCC
MILDLARAWPVSLQGSFVIGDSDSDIEAATAAGIQGFLFEGDDIDAFVSKVLDTMARSDA
CEEECCCCCCCCCCCCEEECCCCCCCHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHCC
AQN
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]