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The map label for this gene is exoB [H]

Identifier: 86748722

GI number: 86748722

Start: 1800656

End: 1801669

Strand: Reverse

Name: exoB [H]

Synonym: RPB_1597

Alternate gene names: 86748722

Gene position: 1801669-1800656 (Counterclockwise)

Preceding gene: 86748724

Following gene: 86748721

Centisome position: 33.79

GC content: 65.88

Gene sequence:

>1014_bases
ATGACCGTGCTCGTGACCGGCGGCGCCGGCTATATCGGAAGCCACACCGTGCTGGCGCTGGTCGAAGCCGGCGAGAGCGT
GGTGGTGATCGACAATCTGAGCACCGGTTTTTCCAGCTTCGTGCCGGAAGGCATACCATTGTTCATCGGGGATGCCGGCG
ACGAGAATCTGGTCGAAGGCGTGATCAGAACCCACGGCGTCGATGCCATCATTCACTTCGCCGGCTCGGTGATCGTCTCG
GAGTCGATGCGCGATCCGCTTGGCTACTATCGCAACAACACTATGACCTCGCGCAATCTGCTGAGCGCGGCAGTGACGTG
CGGCGTGAACAATTTCATCTTCTCGTCGACCGCCGCGGTCTATGGCAATCCCGACCGCACCCCAGTCCCGGAAGAAGCGC
CGACGCGGCCGCTGTCGCCCTATGGCTGCTCCAAGCTGATGACCGAGATCATGCTGCACGACACGGCGTCGGCCAACGGC
ATGAACTACGTGGCGCTGCGCTACTTCAACGTCGCCGGCGCCGATCCGCAGGCGCGGATCGGGCTCGCGACCATCGGCGC
GACGCACCTGCTGAAGATCGCGGTGGAAGCCGCGACCGGCCAACGCGCGCAGATCGAGGTCTACGGCACCGACTATCCGA
CGCCGGACGGAAGCTGCATTCGCGATTTCATCCATGTCAGCGACCTCGCGCAGGCGCATGTCGCAGCCCTCGCCTATCTG
CGCCGGGGCGGCGCGCCGGTGACGCTGAACTGCGGCTACGGCCGCGGCTATTCGGTGCTGGAAACCATCGAGGCGGTGCG
CCGCGTCGCGGGGCGCAACTTCGCCGTGTCCACCGCCGCCCGCCGGCCCGGCGACATCGTGGCGATGGTTGCAGACACGC
GCCGGATTCGCGCGACGCTGGACTGGACCCCGCGCCATGACGACCTCGAAACCATCGCCGCGGATGCGCTGCGCTGGGAG
CGCAAGCTGCTCGCCCAGCGCCAAGGCTTTGATCGGCAAGCGATTCCAGCTTAA

Upstream 100 bases:

>100_bases
GCGGTTTGGCTGCTTGGCTACACCGCAAGTCCATCGTTTGACGAAAGACTGAGGCCGACGGCGCGGGGACGGACCCGCAG
CGCCCACCGAGGAGCCTTCC

Downstream 100 bases:

>100_bases
GTCGGCTCCGGCTCGCCAGCTTTTGGCTTGAAAACCCAGCCCATCGGGGGCAAGGAGGCGTCATTACGCACGCCGATCCA
ACGCGCGCGACCTGTTCGAC

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MTVLVTGGAGYIGSHTVLALVEAGESVVVIDNLSTGFSSFVPEGIPLFIGDAGDENLVEGVIRTHGVDAIIHFAGSVIVS
ESMRDPLGYYRNNTMTSRNLLSAAVTCGVNNFIFSSTAAVYGNPDRTPVPEEAPTRPLSPYGCSKLMTEIMLHDTASANG
MNYVALRYFNVAGADPQARIGLATIGATHLLKIAVEAATGQRAQIEVYGTDYPTPDGSCIRDFIHVSDLAQAHVAALAYL
RRGGAPVTLNCGYGRGYSVLETIEAVRRVAGRNFAVSTAARRPGDIVAMVADTRRIRATLDWTPRHDDLETIAADALRWE
RKLLAQRQGFDRQAIPA

Sequences:

>Translated_337_residues
MTVLVTGGAGYIGSHTVLALVEAGESVVVIDNLSTGFSSFVPEGIPLFIGDAGDENLVEGVIRTHGVDAIIHFAGSVIVS
ESMRDPLGYYRNNTMTSRNLLSAAVTCGVNNFIFSSTAAVYGNPDRTPVPEEAPTRPLSPYGCSKLMTEIMLHDTASANG
MNYVALRYFNVAGADPQARIGLATIGATHLLKIAVEAATGQRAQIEVYGTDYPTPDGSCIRDFIHVSDLAQAHVAALAYL
RRGGAPVTLNCGYGRGYSVLETIEAVRRVAGRNFAVSTAARRPGDIVAMVADTRRIRATLDWTPRHDDLETIAADALRWE
RKLLAQRQGFDRQAIPA
>Mature_336_residues
TVLVTGGAGYIGSHTVLALVEAGESVVVIDNLSTGFSSFVPEGIPLFIGDAGDENLVEGVIRTHGVDAIIHFAGSVIVSE
SMRDPLGYYRNNTMTSRNLLSAAVTCGVNNFIFSSTAAVYGNPDRTPVPEEAPTRPLSPYGCSKLMTEIMLHDTASANGM
NYVALRYFNVAGADPQARIGLATIGATHLLKIAVEAATGQRAQIEVYGTDYPTPDGSCIRDFIHVSDLAQAHVAALAYLR
RGGAPVTLNCGYGRGYSVLETIEAVRRVAGRNFAVSTAARRPGDIVAMVADTRRIRATLDWTPRHDDLETIAADALRWER
KLLAQRQGFDRQAIPA

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=348, Percent_Identity=39.0804597701149, Blast_Score=219, Evalue=2e-57,
Organism=Homo sapiens, GI56118217, Length=348, Percent_Identity=39.0804597701149, Blast_Score=219, Evalue=2e-57,
Organism=Homo sapiens, GI189083684, Length=348, Percent_Identity=39.0804597701149, Blast_Score=219, Evalue=2e-57,
Organism=Homo sapiens, GI42516563, Length=309, Percent_Identity=26.537216828479, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI7657641, Length=354, Percent_Identity=24.0112994350282, Blast_Score=82, Evalue=8e-16,
Organism=Escherichia coli, GI1786974, Length=332, Percent_Identity=40.0602409638554, Blast_Score=224, Evalue=8e-60,
Organism=Escherichia coli, GI1790049, Length=269, Percent_Identity=28.2527881040892, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI48994969, Length=349, Percent_Identity=24.9283667621776, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71982035, Length=349, Percent_Identity=36.9627507163324, Blast_Score=209, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI71982038, Length=351, Percent_Identity=36.7521367521368, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17539532, Length=311, Percent_Identity=24.1157556270096, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319493, Length=335, Percent_Identity=37.6119402985075, Blast_Score=218, Evalue=8e-58,
Organism=Drosophila melanogaster, GI19923002, Length=339, Percent_Identity=38.6430678466077, Blast_Score=219, Evalue=2e-57,
Organism=Drosophila melanogaster, GI21356223, Length=342, Percent_Identity=26.3157894736842, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36051; Mature: 35920

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLVTGGAGYIGSHTVLALVEAGESVVVIDNLSTGFSSFVPEGIPLFIGDAGDENLVEG
CEEEEECCCCCCCCHHEEEEEECCCEEEEEECCCCCHHHHCCCCCEEEEECCCCHHHHHH
VIRTHGVDAIIHFAGSVIVSESMRDPLGYYRNNTMTSRNLLSAAVTCGVNNFIFSSTAAV
HHHHCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHCCCHHHHCCCEEE
YGNPDRTPVPEEAPTRPLSPYGCSKLMTEIMLHDTASANGMNYVALRYFNVAGADPQARI
ECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCEE
GLATIGATHLLKIAVEAATGQRAQIEVYGTDYPTPDGSCIRDFIHVSDLAQAHVAALAYL
EEEHHHHHHHHHHHEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RRGGAPVTLNCGYGRGYSVLETIEAVRRVAGRNFAVSTAARRPGDIVAMVADTRRIRATL
HCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEECCEEEEEEE
DWTPRHDDLETIAADALRWERKLLAQRQGFDRQAIPA
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TVLVTGGAGYIGSHTVLALVEAGESVVVIDNLSTGFSSFVPEGIPLFIGDAGDENLVEG
EEEEECCCCCCCCHHEEEEEECCCEEEEEECCCCCHHHHCCCCCEEEEECCCCHHHHHH
VIRTHGVDAIIHFAGSVIVSESMRDPLGYYRNNTMTSRNLLSAAVTCGVNNFIFSSTAAV
HHHHCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHCCCHHHHCCCEEE
YGNPDRTPVPEEAPTRPLSPYGCSKLMTEIMLHDTASANGMNYVALRYFNVAGADPQARI
ECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCEE
GLATIGATHLLKIAVEAATGQRAQIEVYGTDYPTPDGSCIRDFIHVSDLAQAHVAALAYL
EEEHHHHHHHHHHHEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RRGGAPVTLNCGYGRGYSVLETIEAVRRVAGRNFAVSTAARRPGDIVAMVADTRRIRATL
HCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEECCEEEEEEE
DWTPRHDDLETIAADALRWERKLLAQRQGFDRQAIPA
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8026752 [H]