Click here to switch to the map view.

The map label for this gene is yngJ [H]

Identifier: 86748271

GI number: 86748271

Start: 1318043

End: 1319338

Strand: Reverse

Name: yngJ [H]

Synonym: RPB_1146

Alternate gene names: 86748271

Gene position: 1319338-1318043 (Counterclockwise)

Preceding gene: 86748280

Following gene: 86748265

Centisome position: 24.75

GC content: 65.12

Gene sequence:

>1296_bases
ATGATCACATCGGGAGGAACCACGATGGAATTGGCCTATGTGCCCCGCCACACCCCCTACACGCTCGCTCCGGAAGACGA
ACTGAACGACCTGCGGATGTCCGAGAAGGTCCGGCCGCTGTACGACCACGTCAAGAAGTTCATCGCCGAGACCGTCGAGC
CGATGTCGCACGAATTCGAGGCGGCCGGCGAAGGCAACCCGAACCGCTGGTCGTTCACCGACAAGCAGCTCGAGATTCTC
GGCAAGGCCAAGAACAAGGCCAAGGACGTCGGCCTGTGGAACTTCTTCCTGCCCGACGCCGAGACCGGCGAGGGCCTGAA
CAATCTCGACTACGCCTATATCGCCGCCGAGCTCGGCAAGGCGCCGCTCGCCTCCGAGGTGATGAACTGCTCGGCGCCCG
ACACCGGCAACATGGAAGTGCTGGAGCGGGTCGGCACCGCCGCGCAGAAGGAGAAGTGGCTGAAGCCGCTGCTCAACGGC
GAGATCCGCTCGGCCTATGTGATGACCGAGCCGAACGTCGCCTCCTCCGACGCCAAGAACGTCTCGACCTCGGCCAAGCT
CGACGGCGACGAGTGGGTGATCAACGGCGAGAAGTACTACATCTCCGGCCTCGGCGACCCGCGCTGCAAGATCATGATCG
TGATGGTCAAGACCGACCCGACCGCGGCGCCCAGCAAGCAGCAATCGCAGATCCTCGTGCCGGTCGACACCCCCGGCGTC
GAGGTGATCGGCCCGATGCACGTGTTCGGCCACGACCACGCGCCGCGCGGCCACATGCACATGCGCTTCAACAATGTGCG
GGTGCCGAAGGAGAACATCCTGCTCGGCGAGGGCCGCGGCTTCGAGATTTCGCAGCTCCGGCTCGGCCCCGGCCGCATTC
ATCATTGCATGCGCACCATCGGCAAGGCCGAGAAGGCGCTCGACATGATGGTGGTGCGCGGCCTGACCCGGGTGGCTTTC
GGCCAGAAGATCGCGCATCTCGGCGGCAACATGCAGATCATCGCGCAGGCCCGCTGCGAGATCGAGGCGATGCGGCTGAT
GGTGCTGAAGGCCGCCAAGGCGATGGACGTGCTCGGCAACAAGGAAGCCCGCGTCTGGGTCAGCATGGTCAAGGCCATGG
TGCCCGAGCGCGCCTGCAAGATCATCGACCAGGCGATCCAGATGCACGGCGCCACCGGCATCTCGCAATGGACCCCGCTG
GCCGAGATGTACACCGACGTCCGCCACCTGCGCTTCGCCGACGGCCCGGACGAGGTGCACTGGATGGTGGTGGGGCGGCA
TGAGTTGACGCTGTAA

Upstream 100 bases:

>100_bases
CGTGCATCCGGCCTGCCGCCGCGCCGGCACACCTTCGACAAGCGCACGCGTTCATGTCTATAAAGGACCCGCAACCATCC
ACTCAGGATGGGGAAACGCG

Downstream 100 bases:

>100_bases
GGCGCTTCTTACTGATAGACGCGGTCTCTCCGCTGTTTCCGCCGTCATCCTGAGGTGCCCGTCGTATCGCGCAACGCGCG
ATGCGACGGGCCTCGAAGGA

Product: Acyl-CoA dehydrogenase-like

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MITSGGTTMELAYVPRHTPYTLAPEDELNDLRMSEKVRPLYDHVKKFIAETVEPMSHEFEAAGEGNPNRWSFTDKQLEIL
GKAKNKAKDVGLWNFFLPDAETGEGLNNLDYAYIAAELGKAPLASEVMNCSAPDTGNMEVLERVGTAAQKEKWLKPLLNG
EIRSAYVMTEPNVASSDAKNVSTSAKLDGDEWVINGEKYYISGLGDPRCKIMIVMVKTDPTAAPSKQQSQILVPVDTPGV
EVIGPMHVFGHDHAPRGHMHMRFNNVRVPKENILLGEGRGFEISQLRLGPGRIHHCMRTIGKAEKALDMMVVRGLTRVAF
GQKIAHLGGNMQIIAQARCEIEAMRLMVLKAAKAMDVLGNKEARVWVSMVKAMVPERACKIIDQAIQMHGATGISQWTPL
AEMYTDVRHLRFADGPDEVHWMVVGRHELTL

Sequences:

>Translated_431_residues
MITSGGTTMELAYVPRHTPYTLAPEDELNDLRMSEKVRPLYDHVKKFIAETVEPMSHEFEAAGEGNPNRWSFTDKQLEIL
GKAKNKAKDVGLWNFFLPDAETGEGLNNLDYAYIAAELGKAPLASEVMNCSAPDTGNMEVLERVGTAAQKEKWLKPLLNG
EIRSAYVMTEPNVASSDAKNVSTSAKLDGDEWVINGEKYYISGLGDPRCKIMIVMVKTDPTAAPSKQQSQILVPVDTPGV
EVIGPMHVFGHDHAPRGHMHMRFNNVRVPKENILLGEGRGFEISQLRLGPGRIHHCMRTIGKAEKALDMMVVRGLTRVAF
GQKIAHLGGNMQIIAQARCEIEAMRLMVLKAAKAMDVLGNKEARVWVSMVKAMVPERACKIIDQAIQMHGATGISQWTPL
AEMYTDVRHLRFADGPDEVHWMVVGRHELTL
>Mature_431_residues
MITSGGTTMELAYVPRHTPYTLAPEDELNDLRMSEKVRPLYDHVKKFIAETVEPMSHEFEAAGEGNPNRWSFTDKQLEIL
GKAKNKAKDVGLWNFFLPDAETGEGLNNLDYAYIAAELGKAPLASEVMNCSAPDTGNMEVLERVGTAAQKEKWLKPLLNG
EIRSAYVMTEPNVASSDAKNVSTSAKLDGDEWVINGEKYYISGLGDPRCKIMIVMVKTDPTAAPSKQQSQILVPVDTPGV
EVIGPMHVFGHDHAPRGHMHMRFNNVRVPKENILLGEGRGFEISQLRLGPGRIHHCMRTIGKAEKALDMMVVRGLTRVAF
GQKIAHLGGNMQIIAQARCEIEAMRLMVLKAAKAMDVLGNKEARVWVSMVKAMVPERACKIIDQAIQMHGATGISQWTPL
AEMYTDVRHLRFADGPDEVHWMVVGRHELTL

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI211971008, Length=402, Percent_Identity=49.7512437810945, Blast_Score=394, Evalue=1e-109,
Organism=Homo sapiens, GI48976061, Length=402, Percent_Identity=49.7512437810945, Blast_Score=393, Evalue=1e-109,
Organism=Homo sapiens, GI38505218, Length=391, Percent_Identity=49.616368286445, Blast_Score=366, Evalue=1e-101,
Organism=Homo sapiens, GI187960098, Length=401, Percent_Identity=24.6882793017456, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI4557231, Length=400, Percent_Identity=24.75, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI4557233, Length=346, Percent_Identity=29.4797687861272, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI226958412, Length=420, Percent_Identity=27.3809523809524, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI7656849, Length=372, Percent_Identity=28.7634408602151, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI4501859, Length=325, Percent_Identity=26.7692307692308, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI21361497, Length=411, Percent_Identity=25.0608272506083, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI4557235, Length=400, Percent_Identity=28, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI76496475, Length=400, Percent_Identity=28, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI226958414, Length=341, Percent_Identity=27.8592375366569, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI4501857, Length=414, Percent_Identity=24.8792270531401, Blast_Score=94, Evalue=3e-19,
Organism=Escherichia coli, GI87081958, Length=310, Percent_Identity=27.741935483871, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17562446, Length=403, Percent_Identity=46.8982630272953, Blast_Score=371, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17534899, Length=405, Percent_Identity=27.1604938271605, Blast_Score=134, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI17570075, Length=403, Percent_Identity=24.8138957816377, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI71985184, Length=342, Percent_Identity=27.4853801169591, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17569725, Length=423, Percent_Identity=25.0591016548463, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17533517, Length=385, Percent_Identity=25.7142857142857, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17508101, Length=420, Percent_Identity=25.4761904761905, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17506239, Length=433, Percent_Identity=26.0969976905312, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71990804, Length=280, Percent_Identity=30, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17538396, Length=433, Percent_Identity=25.4041570438799, Blast_Score=101, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17505929, Length=384, Percent_Identity=25.2604166666667, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17551932, Length=424, Percent_Identity=23.3490566037736, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI71985192, Length=296, Percent_Identity=26.0135135135135, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71982178, Length=293, Percent_Identity=25.938566552901, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI32563615, Length=228, Percent_Identity=27.6315789473684, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24660351, Length=402, Percent_Identity=27.363184079602, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI281363737, Length=342, Percent_Identity=27.1929824561404, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24646207, Length=339, Percent_Identity=29.2035398230088, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24666513, Length=268, Percent_Identity=32.089552238806, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21356377, Length=357, Percent_Identity=28.0112044817927, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI21355753, Length=376, Percent_Identity=25, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 47804; Mature: 47804

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITSGGTTMELAYVPRHTPYTLAPEDELNDLRMSEKVRPLYDHVKKFIAETVEPMSHEFE
CCCCCCCEEEEEECCCCCCEEECCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHC
AAGEGNPNRWSFTDKQLEILGKAKNKAKDVGLWNFFLPDAETGEGLNNLDYAYIAAELGK
CCCCCCCCCCCCCHHHHHHHHHHHCHHHHCCEEEEECCCCCCCCCCCCCCHHHHHHHHCC
APLASEVMNCSAPDTGNMEVLERVGTAAQKEKWLKPLLNGEIRSAYVMTEPNVASSDAKN
CCCHHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC
VSTSAKLDGDEWVINGEKYYISGLGDPRCKIMIVMVKTDPTAAPSKQQSQILVPVDTPGV
CCCCCEECCCEEEECCCEEEEECCCCCCEEEEEEEEECCCCCCCCCCCCEEEEEECCCCC
EVIGPMHVFGHDHAPRGHMHMRFNNVRVPKENILLGEGRGFEISQLRLGPGRIHHCMRTI
EEEECEEEECCCCCCCCCEEEEECCEECCHHHEEEECCCCCEEEEEECCHHHHHHHHHHH
GKAEKALDMMVVRGLTRVAFGQKIAHLGGNMQIIAQARCEIEAMRLMVLKAAKAMDVLGN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCC
KEARVWVSMVKAMVPERACKIIDQAIQMHGATGISQWTPLAEMYTDVRHLRFADGPDEVH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHCCCCCCCCEE
WMVVGRHELTL
EEEEECEECCC
>Mature Secondary Structure
MITSGGTTMELAYVPRHTPYTLAPEDELNDLRMSEKVRPLYDHVKKFIAETVEPMSHEFE
CCCCCCCEEEEEECCCCCCEEECCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHC
AAGEGNPNRWSFTDKQLEILGKAKNKAKDVGLWNFFLPDAETGEGLNNLDYAYIAAELGK
CCCCCCCCCCCCCHHHHHHHHHHHCHHHHCCEEEEECCCCCCCCCCCCCCHHHHHHHHCC
APLASEVMNCSAPDTGNMEVLERVGTAAQKEKWLKPLLNGEIRSAYVMTEPNVASSDAKN
CCCHHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC
VSTSAKLDGDEWVINGEKYYISGLGDPRCKIMIVMVKTDPTAAPSKQQSQILVPVDTPGV
CCCCCEECCCEEEECCCEEEEECCCCCCEEEEEEEEECCCCCCCCCCCCEEEEEECCCCC
EVIGPMHVFGHDHAPRGHMHMRFNNVRVPKENILLGEGRGFEISQLRLGPGRIHHCMRTI
EEEECEEEECCCCCCCCCEEEEECCEECCHHHEEEECCCCCEEEEEECCHHHHHHHHHHH
GKAEKALDMMVVRGLTRVAFGQKIAHLGGNMQIIAQARCEIEAMRLMVLKAAKAMDVLGN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCC
KEARVWVSMVKAMVPERACKIIDQAIQMHGATGISQWTPLAEMYTDVRHLRFADGPDEVH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHCCCCCCCCEE
WMVVGRHELTL
EEEEECEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]