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The map label for this gene is mcp4 [H]

Identifier: 86748197

GI number: 86748197

Start: 1230995

End: 1232230

Strand: Direct

Name: mcp4 [H]

Synonym: RPB_1072

Alternate gene names: 86748197

Gene position: 1230995-1232230 (Clockwise)

Preceding gene: 86748196

Following gene: 86748199

Centisome position: 23.09

GC content: 68.45

Gene sequence:

>1236_bases
ATGAATTATCCGACGGCGGCGTTGTCGCTGCAGGCGGTCGCGCTCGTGGCGGCGGCGCTGGCGTTTATCGGCGTGACCGG
AACGGCGCGGCGGATCGAGCAGGCGCGCGACGTCTGCCGGCGGGTCGCCGACGGCGATTTCGAGGCCCGCATCCTGCACA
TTCCGACCTCCGGCCGCCTCGGCGAAATGCTCGGCGCGATCAACGACGTGGTCGACGATTGCGATGCCTTCGTGCGGGAA
GCCACCGCGTCGATGCATGCCGTTCAGCATCACCACTATTTCCGGCGGATCCTGCCCGGCGGCCTGCACGGCGCGCTGCT
GCGCGGCGCCACCACGATCAACCACGCCACCGACAGCATCGAAGCCCGCATCCGGAGCTTCGATCAACAGGCCGCCGGAC
TCGAGCGGGCCGTCAGTGACGTCGTCGGCGCGCTCGACGAGGATTCTTCCGGCATGCGCGACACCGCGAGCAATCTGACC
CGCGGCGCATCAACGACCCGCGAGAGCCTCACCGCGGTCGCCGTGGCGTCGGAACAGGCCAGCGGCAACATGCGCTCGGT
GGCGAACGCCACCGCCGGCTTGTCGTCCAGCGCCCGCGCGGTCGGCGCGGATATCGGCCGTTCGTCCGAGATCGTCAGCC
GCGCCGTCACGCGCGTGTCGGAAGCCTCCGCCGACGTCGCCAAGTTGCGCGACGTCGCCGAACGGATCAGTCAGGTGGTG
AAGTCGATCGAGACCATCGCCAGCCAGACCAATCTGCTGGCGCTCAATGCCACCATCGAAGCGGCGCGCGCCGGCGATGC
CGGCCGCGGCTTCGCCGTCGTCGCCCACGAAGTCAAGTCGCTCGCCGAACAGACCGCGAAGTTCACCGGCGAGATCGAGG
CGCAGGTCGATCACGTCCACGGCGCCGCGGACGCGGTCAGCACGTCGATCGGCGAGATCGGCGCGGTGATGACGGAAGTC
GTCGGCATCACCGGAACCATCGCCGAAGCCGCCGAGGCACAGTCGGTCGCGACCGCGGAGATCGCGCAGAACATCGAGCA
GGCGTTCGCGATGGTGAGCGATATCGCCAGCAGCATCCAGACCGTCACCGCGACCGCGCGCGAAACCGAGAGCTACGCCG
CCGCGACAATGACGACGTCGAATCACCTGTCGTCCAATTCGGGGACGCTGGCACGGCAGATCCGCGACTATCTCGACCAG
GTGCGCAAGGACCTGATCGAGCAGAACGCGGCGTAG

Upstream 100 bases:

>100_bases
AAGAAGGTCAGCTATGACGAACTCATGTTCGCTCTCCAGAGCGCAGCTTAGCCTCGCGGTCGTAATCGCCTCTGCGGCGC
TCGCAGCCGCGCTGGCCTGG

Downstream 100 bases:

>100_bases
TCGCGTTCGGCGCCACGCGGATCTGAAGCCGCGCTGCGTTGGTCTCGGTCGTGTGAAGTCGAGCCAGACCGGATCAATTC
ATGGTTCGAGACGGCGCTAC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MNYPTAALSLQAVALVAAALAFIGVTGTARRIEQARDVCRRVADGDFEARILHIPTSGRLGEMLGAINDVVDDCDAFVRE
ATASMHAVQHHHYFRRILPGGLHGALLRGATTINHATDSIEARIRSFDQQAAGLERAVSDVVGALDEDSSGMRDTASNLT
RGASTTRESLTAVAVASEQASGNMRSVANATAGLSSSARAVGADIGRSSEIVSRAVTRVSEASADVAKLRDVAERISQVV
KSIETIASQTNLLALNATIEAARAGDAGRGFAVVAHEVKSLAEQTAKFTGEIEAQVDHVHGAADAVSTSIGEIGAVMTEV
VGITGTIAEAAEAQSVATAEIAQNIEQAFAMVSDIASSIQTVTATARETESYAAATMTTSNHLSSNSGTLARQIRDYLDQ
VRKDLIEQNAA

Sequences:

>Translated_411_residues
MNYPTAALSLQAVALVAAALAFIGVTGTARRIEQARDVCRRVADGDFEARILHIPTSGRLGEMLGAINDVVDDCDAFVRE
ATASMHAVQHHHYFRRILPGGLHGALLRGATTINHATDSIEARIRSFDQQAAGLERAVSDVVGALDEDSSGMRDTASNLT
RGASTTRESLTAVAVASEQASGNMRSVANATAGLSSSARAVGADIGRSSEIVSRAVTRVSEASADVAKLRDVAERISQVV
KSIETIASQTNLLALNATIEAARAGDAGRGFAVVAHEVKSLAEQTAKFTGEIEAQVDHVHGAADAVSTSIGEIGAVMTEV
VGITGTIAEAAEAQSVATAEIAQNIEQAFAMVSDIASSIQTVTATARETESYAAATMTTSNHLSSNSGTLARQIRDYLDQ
VRKDLIEQNAA
>Mature_411_residues
MNYPTAALSLQAVALVAAALAFIGVTGTARRIEQARDVCRRVADGDFEARILHIPTSGRLGEMLGAINDVVDDCDAFVRE
ATASMHAVQHHHYFRRILPGGLHGALLRGATTINHATDSIEARIRSFDQQAAGLERAVSDVVGALDEDSSGMRDTASNLT
RGASTTRESLTAVAVASEQASGNMRSVANATAGLSSSARAVGADIGRSSEIVSRAVTRVSEASADVAKLRDVAERISQVV
KSIETIASQTNLLALNATIEAARAGDAGRGFAVVAHEVKSLAEQTAKFTGEIEAQVDHVHGAADAVSTSIGEIGAVMTEV
VGITGTIAEAAEAQSVATAEIAQNIEQAFAMVSDIASSIQTVTATARETESYAAATMTTSNHLSSNSGTLARQIRDYLDQ
VRKDLIEQNAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=120, Percent_Identity=42.5, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788195, Length=228, Percent_Identity=30.7017543859649, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788194, Length=251, Percent_Identity=29.4820717131474, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787690, Length=149, Percent_Identity=36.9127516778523, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789453, Length=170, Percent_Identity=32.9411764705882, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 42809; Mature: 42809

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYPTAALSLQAVALVAAALAFIGVTGTARRIEQARDVCRRVADGDFEARILHIPTSGRL
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCH
GEMLGAINDVVDDCDAFVREATASMHAVQHHHYFRRILPGGLHGALLRGATTINHATDSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHH
EARIRSFDQQAAGLERAVSDVVGALDEDSSGMRDTASNLTRGASTTRESLTAVAVASEQA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHC
SGNMRSVANATAGLSSSARAVGADIGRSSEIVSRAVTRVSEASADVAKLRDVAERISQVV
CCCHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSIETIASQTNLLALNATIEAARAGDAGRGFAVVAHEVKSLAEQTAKFTGEIEAQVDHVH
HHHHHHHHCCCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
GAADAVSTSIGEIGAVMTEVVGITGTIAEAAEAQSVATAEIAQNIEQAFAMVSDIASSIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVTATARETESYAAATMTTSNHLSSNSGTLARQIRDYLDQVRKDLIEQNAA
HHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNYPTAALSLQAVALVAAALAFIGVTGTARRIEQARDVCRRVADGDFEARILHIPTSGRL
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCH
GEMLGAINDVVDDCDAFVREATASMHAVQHHHYFRRILPGGLHGALLRGATTINHATDSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHH
EARIRSFDQQAAGLERAVSDVVGALDEDSSGMRDTASNLTRGASTTRESLTAVAVASEQA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHC
SGNMRSVANATAGLSSSARAVGADIGRSSEIVSRAVTRVSEASADVAKLRDVAERISQVV
CCCHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSIETIASQTNLLALNATIEAARAGDAGRGFAVVAHEVKSLAEQTAKFTGEIEAQVDHVH
HHHHHHHHCCCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
GAADAVSTSIGEIGAVMTEVVGITGTIAEAAEAQSVATAEIAQNIEQAFAMVSDIASSIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVTATARETESYAAATMTTSNHLSSNSGTLARQIRDYLDQVRKDLIEQNAA
HHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]