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The map label for this gene is tsr [C]

Identifier: 86748015

GI number: 86748015

Start: 1018199

End: 1019821

Strand: Reverse

Name: tsr [C]

Synonym: RPB_0889

Alternate gene names: 86748015

Gene position: 1019821-1018199 (Counterclockwise)

Preceding gene: 86748016

Following gene: 86748012

Centisome position: 19.13

GC content: 64.51

Gene sequence:

>1623_bases
ATGACGGCGATTTTTGGGGCAAGCCTGTATGGGCTGTCGCAACTCAAGGTCGGCGGACCGCTGTATGACCAGATCAAACT
CGGCAACGATCTGGTGGCCGACATCCTGCCGCCGCCCGCTTACGTGATTGAAGCCTATCTGGAGGCGACGCTGGCGATCG
AGGAGCCCGATTCGTTCCCGCTCCGCCGCGAGCGGCTCGGCCGACTTAAGAAAGAATACCAGGACCGCCACGCATTCTGG
CTCACCGCGCCGCTCGATCCGGCGATCAAGGCACGCCTGATCGACGATTCCGACCGCGAAGTGAAGAAGTTCTGGGACAT
TCTGGAGGCCAGCCTGTTCCCGGCGATCGAGAGCAAGGATCCCGACACGGCGATGCAGGCCTACAGGGACCTGACCAAGG
CCTACACGGCGCATCGCGCCATCATCGACGATATCGTCAAACGGACCAACGATCTGAATGCCGCAACCGAAGCGGCGACG
GCGGTGCGCGCGGCCGATCTCAACTATCTGCTGTGGGGTGTATCGTCCGCGGTCTTCTTATTGTTCATCGCGGGCCTGAC
CGGGATCGTGAAAGGCGTGATCGCGCCGATCACCGGGATGACGGAGGTGATGCGCCGTCTCGCTGACGGAGACCGCTCGG
TGGCGATTCCCGCGATCGAGCGCGGCGACGAGGTCGGCGCGATGGCGCGGGCGGTGCAGGTGTTCAAGGACAACGCGCTG
CGGGTCGAAGCGATGGAATCCGAAAAGGGGGTGAAGGCGCGCGCCGACGCGAACCGTCGGGCTGAAATGCAGAAGATTGC
CGATGAGTTGGATGGCGCGATCGGCAGGATCGTCCAAACCGTGACGGCGACGTCCACCGAAATGGAAGCGGCCGCAAGCC
AACTGGCTGGCAACGTCGATTCCACGCAGCGGCTGGCAACTACCGTGGCGACCGCTTCACAACAGTCCAGCGCGACCGCA
CAATCAACCGCCGTCACCTGCAACGAGGTCGCCTCGTCCGCATCCCAGATCGGACAGCAAGTCCGGCAGGCGCAAAACAT
CTCACAGGCCGCCGTCCGGCAGGCGCAGGAGACCAACGCGCGTATCGCCGACCTTTCGACCGCGGCCGGTCGTATCGGCG
ATGTCGTCAATCTGATCAACGCGGTCGCGGCACAGACCAATTTGCTGGCGCTCAATGCGACGATCGAAGCCGCCCGCGCC
GGCGAGGCGGGACGCGGCTTTGCCGTCGTCGCCTCGGAGGTCAAGGCGCTCGCATCCCAGACCGCAAAAGCGACCGAGGA
GATTACCGAACAGATTTCCCAAATGAAGACGGCGACCGAATTGTCGGTGTCGGCGATCGAAGCGATCGGCACCACCATTC
TTCAGATCTCGGAAATCTCGGATGCGACCGCATCGGCGGTCGACCAGCAGGGCGCCGCGATGCGCGAGATTGCCGTCAGC
GTCCGGGAGTCGGCGGACGCGGCGACCGACGTCTCAAACACGATCGGGACGGTGCGCGAGGGCGCCGAGGACACCGGCTC
GGCGTCCGCGCATGTCCACGATCTGGCCGCCTCGCTGCTCGCGGAAAGCCGCCACCTCAAGACCGAGGTCGACCGCTTCT
CGGCAGCGGTGCGCGCCGCTTGA

Upstream 100 bases:

>100_bases
ATATCCGGGGGTTCGGCCACTCGCACGACGATCGGAACAACAGATGCGACTGACGATTACGCGCGCCGTCCTTCTTTTTG
GGCTCATCATCGGGTCCGGC

Downstream 100 bases:

>100_bases
TCAAGTCTTGCGAGACTACGCGCTGCGCGCCAGCGCGCCGTCGATCATCGCGACCGCATTGTTGAGGCCGTAGACCGCCA
CGAAGGAGCCGAAGCGCGGG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 540; Mature: 539

Protein sequence:

>540_residues
MTAIFGASLYGLSQLKVGGPLYDQIKLGNDLVADILPPPAYVIEAYLEATLAIEEPDSFPLRRERLGRLKKEYQDRHAFW
LTAPLDPAIKARLIDDSDREVKKFWDILEASLFPAIESKDPDTAMQAYRDLTKAYTAHRAIIDDIVKRTNDLNAATEAAT
AVRAADLNYLLWGVSSAVFLLFIAGLTGIVKGVIAPITGMTEVMRRLADGDRSVAIPAIERGDEVGAMARAVQVFKDNAL
RVEAMESEKGVKARADANRRAEMQKIADELDGAIGRIVQTVTATSTEMEAAASQLAGNVDSTQRLATTVATASQQSSATA
QSTAVTCNEVASSASQIGQQVRQAQNISQAAVRQAQETNARIADLSTAAGRIGDVVNLINAVAAQTNLLALNATIEAARA
GEAGRGFAVVASEVKALASQTAKATEEITEQISQMKTATELSVSAIEAIGTTILQISEISDATASAVDQQGAAMREIAVS
VRESADAATDVSNTIGTVREGAEDTGSASAHVHDLAASLLAESRHLKTEVDRFSAAVRAA

Sequences:

>Translated_540_residues
MTAIFGASLYGLSQLKVGGPLYDQIKLGNDLVADILPPPAYVIEAYLEATLAIEEPDSFPLRRERLGRLKKEYQDRHAFW
LTAPLDPAIKARLIDDSDREVKKFWDILEASLFPAIESKDPDTAMQAYRDLTKAYTAHRAIIDDIVKRTNDLNAATEAAT
AVRAADLNYLLWGVSSAVFLLFIAGLTGIVKGVIAPITGMTEVMRRLADGDRSVAIPAIERGDEVGAMARAVQVFKDNAL
RVEAMESEKGVKARADANRRAEMQKIADELDGAIGRIVQTVTATSTEMEAAASQLAGNVDSTQRLATTVATASQQSSATA
QSTAVTCNEVASSASQIGQQVRQAQNISQAAVRQAQETNARIADLSTAAGRIGDVVNLINAVAAQTNLLALNATIEAARA
GEAGRGFAVVASEVKALASQTAKATEEITEQISQMKTATELSVSAIEAIGTTILQISEISDATASAVDQQGAAMREIAVS
VRESADAATDVSNTIGTVREGAEDTGSASAHVHDLAASLLAESRHLKTEVDRFSAAVRAA
>Mature_539_residues
TAIFGASLYGLSQLKVGGPLYDQIKLGNDLVADILPPPAYVIEAYLEATLAIEEPDSFPLRRERLGRLKKEYQDRHAFWL
TAPLDPAIKARLIDDSDREVKKFWDILEASLFPAIESKDPDTAMQAYRDLTKAYTAHRAIIDDIVKRTNDLNAATEAATA
VRAADLNYLLWGVSSAVFLLFIAGLTGIVKGVIAPITGMTEVMRRLADGDRSVAIPAIERGDEVGAMARAVQVFKDNALR
VEAMESEKGVKARADANRRAEMQKIADELDGAIGRIVQTVTATSTEMEAAASQLAGNVDSTQRLATTVATASQQSSATAQ
STAVTCNEVASSASQIGQQVRQAQNISQAAVRQAQETNARIADLSTAAGRIGDVVNLINAVAAQTNLLALNATIEAARAG
EAGRGFAVVASEVKALASQTAKATEEITEQISQMKTATELSVSAIEAIGTTILQISEISDATASAVDQQGAAMREIAVSV
RESADAATDVSNTIGTVREGAEDTGSASAHVHDLAASLLAESRHLKTEVDRFSAAVRAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=441, Percent_Identity=26.3038548752834, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1788195, Length=205, Percent_Identity=34.6341463414634, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1787690, Length=287, Percent_Identity=30.6620209059233, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1788194, Length=207, Percent_Identity=33.8164251207729, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1789453, Length=269, Percent_Identity=28.2527881040892, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 57135; Mature: 57004

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAIFGASLYGLSQLKVGGPLYDQIKLGNDLVADILPPPAYVIEAYLEATLAIEEPDSFP
CCCEECHHHHHHHHHCCCCCCHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHEEECCCCCC
LRRERLGRLKKEYQDRHAFWLTAPLDPAIKARLIDDSDREVKKFWDILEASLFPAIESKD
HHHHHHHHHHHHHCCCCEEEEECCCCHHHHEEECCCCHHHHHHHHHHHHHHHCCCCCCCC
PDTAMQAYRDLTKAYTAHRAIIDDIVKRTNDLNAATEAATAVRAADLNYLLWGVSSAVFL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHH
LFIAGLTGIVKGVIAPITGMTEVMRRLADGDRSVAIPAIERGDEVGAMARAVQVFKDNAL
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEECCCHHCCCHHHHHHHHHHHHHCCCE
RVEAMESEKGVKARADANRRAEMQKIADELDGAIGRIVQTVTATSTEMEAAASQLAGNVD
EEEEHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCC
STQRLATTVATASQQSSATAQSTAVTCNEVASSASQIGQQVRQAQNISQAAVRQAQETNA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RIADLSTAAGRIGDVVNLINAVAAQTNLLALNATIEAARAGEAGRGFAVVASEVKALASQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHH
TAKATEEITEQISQMKTATELSVSAIEAIGTTILQISEISDATASAVDQQGAAMREIAVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VRESADAATDVSNTIGTVREGAEDTGSASAHVHDLAASLLAESRHLKTEVDRFSAAVRAA
HHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TAIFGASLYGLSQLKVGGPLYDQIKLGNDLVADILPPPAYVIEAYLEATLAIEEPDSFP
CCEECHHHHHHHHHCCCCCCHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHEEECCCCCC
LRRERLGRLKKEYQDRHAFWLTAPLDPAIKARLIDDSDREVKKFWDILEASLFPAIESKD
HHHHHHHHHHHHHCCCCEEEEECCCCHHHHEEECCCCHHHHHHHHHHHHHHHCCCCCCCC
PDTAMQAYRDLTKAYTAHRAIIDDIVKRTNDLNAATEAATAVRAADLNYLLWGVSSAVFL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHH
LFIAGLTGIVKGVIAPITGMTEVMRRLADGDRSVAIPAIERGDEVGAMARAVQVFKDNAL
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEECCCHHCCCHHHHHHHHHHHHHCCCE
RVEAMESEKGVKARADANRRAEMQKIADELDGAIGRIVQTVTATSTEMEAAASQLAGNVD
EEEEHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCC
STQRLATTVATASQQSSATAQSTAVTCNEVASSASQIGQQVRQAQNISQAAVRQAQETNA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RIADLSTAAGRIGDVVNLINAVAAQTNLLALNATIEAARAGEAGRGFAVVASEVKALASQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHH
TAKATEEITEQISQMKTATELSVSAIEAIGTTILQISEISDATASAVDQQGAAMREIAVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VRESADAATDVSNTIGTVREGAEDTGSASAHVHDLAASLLAESRHLKTEVDRFSAAVRAA
HHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]