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The map label for this gene is aprE [H]

Identifier: 86747927

GI number: 86747927

Start: 898198

End: 899520

Strand: Reverse

Name: aprE [H]

Synonym: RPB_0801

Alternate gene names: 86747927

Gene position: 899520-898198 (Counterclockwise)

Preceding gene: 86747928

Following gene: 86747926

Centisome position: 16.87

GC content: 68.18

Gene sequence:

>1323_bases
ATGACCCAACCCGCCGTGACAGAAGACCGCCGCAGCGCGCCGTTCCGCGATGTCCGAAACGCCGTGATCATCGGCGTGGC
AGCGCTCGCGATCGTGATCTCGACGGCTGGCGTCTGGGCCGTGACGGCGCCGATCGCCAGCGCGGTGATCGCGCCGGCGC
AGGTGGTGGTCGACAGCAATGTCCGCCGCATCCAGCACCCGACCGGCGGCGTGGTCGCCGGCATCTCCGTCAACGACGGC
GACTACGTTCACGCCGGCGACGAACTGCTCCGGCTCGACGAAACCCTGCCGCGCGCCAATCTGGCGCTGATCGAGAATCA
GCTCAACCAGTTCTGGACAAGGCGGGCCCGGCTGCAGGCCGAGCAGAACGGGCGCGACGCCATGCCGGTGCCGGTCGAAC
TGACCGGCCGCACCGACGAGCCGGCGATCGCGCAGATCATCGAGGGCGAGACCGCGCTGCTGCTGCGGCGGCGCGAAGCG
ATCACCGGCCAGCAATCGCAATTGGGCGAACGCAAATCCCAGATCGGCGAGGAAATCCGCGGACTGGCCGCGCAGATCGA
TTCGAAGCGCGAACAGATCCGTCTGATCCAGCGCGAGCTCGAAGGCGTCCGGCAGTTGTTCGACAAGAACCTGATCCCCT
ATGCCCGCCTGACCGCGCTGGAGCGCGAAGCCGCCCGCCTCACCGGCGAGGAAGGCCAGCTGATCGCCGACACCGCACGG
GCGAAGGGGCGTATCACCGAGACCGAGCTGCAGATCATCCAGCTCACGCAGGATCAGCGCCGCGAGGTCGCGACCGACCT
GCGCGAGGTCGAGATCAAGATCGCCGATCTGGCGGAACGCCGGATCGCCGCGCAGGACCAGCTCACGCGCGTCGTCCTCC
GCGCGCCGCAGGACGGCCTGATCCATCAGAAGGCGGTGCACACCGTCGGCGGCGTCATCTCGCCCGGCGAACAATTGATG
CTGATCGTGCCCAAGGATTCGTTGGTGATCGAGGCGCGGGTCGAGCCGCAGATGATCGACCGGCTGAAGCCCGGCCAGCC
GGCCAAGCTGCGCTTCACCGCGTTCGACACCGCGGTCACGCCCGAACTCGACGGCACGCTGACCCGCATCGCCGCCGACC
TCACCAAGGATCAGCAATCGGGCGCCGCCTATTATGTGGTCCGGATCAATCTCGCCGAGCGCGAGCTGGCGCGGCTCGAA
GGCAAGGTCCTGGTGCCCGGCATGCCGGTCGAGGCCTACATCCAGAACGGCGTGCGGACCGCGTTGGCCTATCTGAGGAA
ACCGCTCGAGGATCAGCTCGCCCGCGCCTTCCGCCAGCGCTGA

Upstream 100 bases:

>100_bases
AAATCCCTGGCCGGCCAATACAACGCGCCCGGCACTGTCGCCTTGCAGGCGGTGCCGGAATCGCGCCCGCCGACCGCCGC
CGTCAGCTGAGGGGCACGAC

Downstream 100 bases:

>100_bases
GCGCGCGACGGGCGCGCCCGGGAGCGTTGGAGCGGGCGAAGGGAATCGAACCCTCGTATGCAGCTTGGGAAGCTGCCGTT
CTACCATTGAACTACGCCCG

Product: Type I secretion membrane fusion protein, HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MTQPAVTEDRRSAPFRDVRNAVIIGVAALAIVISTAGVWAVTAPIASAVIAPAQVVVDSNVRRIQHPTGGVVAGISVNDG
DYVHAGDELLRLDETLPRANLALIENQLNQFWTRRARLQAEQNGRDAMPVPVELTGRTDEPAIAQIIEGETALLLRRREA
ITGQQSQLGERKSQIGEEIRGLAAQIDSKREQIRLIQRELEGVRQLFDKNLIPYARLTALEREAARLTGEEGQLIADTAR
AKGRITETELQIIQLTQDQRREVATDLREVEIKIADLAERRIAAQDQLTRVVLRAPQDGLIHQKAVHTVGGVISPGEQLM
LIVPKDSLVIEARVEPQMIDRLKPGQPAKLRFTAFDTAVTPELDGTLTRIAADLTKDQQSGAAYYVVRINLAERELARLE
GKVLVPGMPVEAYIQNGVRTALAYLRKPLEDQLARAFRQR

Sequences:

>Translated_440_residues
MTQPAVTEDRRSAPFRDVRNAVIIGVAALAIVISTAGVWAVTAPIASAVIAPAQVVVDSNVRRIQHPTGGVVAGISVNDG
DYVHAGDELLRLDETLPRANLALIENQLNQFWTRRARLQAEQNGRDAMPVPVELTGRTDEPAIAQIIEGETALLLRRREA
ITGQQSQLGERKSQIGEEIRGLAAQIDSKREQIRLIQRELEGVRQLFDKNLIPYARLTALEREAARLTGEEGQLIADTAR
AKGRITETELQIIQLTQDQRREVATDLREVEIKIADLAERRIAAQDQLTRVVLRAPQDGLIHQKAVHTVGGVISPGEQLM
LIVPKDSLVIEARVEPQMIDRLKPGQPAKLRFTAFDTAVTPELDGTLTRIAADLTKDQQSGAAYYVVRINLAERELARLE
GKVLVPGMPVEAYIQNGVRTALAYLRKPLEDQLARAFRQR
>Mature_439_residues
TQPAVTEDRRSAPFRDVRNAVIIGVAALAIVISTAGVWAVTAPIASAVIAPAQVVVDSNVRRIQHPTGGVVAGISVNDGD
YVHAGDELLRLDETLPRANLALIENQLNQFWTRRARLQAEQNGRDAMPVPVELTGRTDEPAIAQIIEGETALLLRRREAI
TGQQSQLGERKSQIGEEIRGLAAQIDSKREQIRLIQRELEGVRQLFDKNLIPYARLTALEREAARLTGEEGQLIADTARA
KGRITETELQIIQLTQDQRREVATDLREVEIKIADLAERRIAAQDQLTRVVLRAPQDGLIHQKAVHTVGGVISPGEQLML
IVPKDSLVIEARVEPQMIDRLKPGQPAKLRFTAFDTAVTPELDGTLTRIAADLTKDQQSGAAYYVVRINLAERELARLEG
KVLVPGMPVEAYIQNGVRTALAYLRKPLEDQLARAFRQR

Specific function: Involved in the secretion of alkaline protease [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 48589; Mature: 48458

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQPAVTEDRRSAPFRDVRNAVIIGVAALAIVISTAGVWAVTAPIASAVIAPAQVVVDSN
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHEEECCC
VRRIQHPTGGVVAGISVNDGDYVHAGDELLRLDETLPRANLALIENQLNQFWTRRARLQA
CHHHCCCCCCEEEEEEECCCCEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
EQNGRDAMPVPVELTGRTDEPAIAQIIEGETALLLRRREAITGQQSQLGERKSQIGEEIR
HCCCCCCCCCCEEECCCCCCHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GLAAQIDSKREQIRLIQRELEGVRQLFDKNLIPYARLTALEREAARLTGEEGQLIADTAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEHHH
AKGRITETELQIIQLTQDQRREVATDLREVEIKIADLAERRIAAQDQLTRVVLRAPQDGL
CCCCCCHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
IHQKAVHTVGGVISPGEQLMLIVPKDSLVIEARVEPQMIDRLKPGQPAKLRFTAFDTAVT
HHHHHHHHHCCCCCCCCCEEEEECCCCEEEEEECCHHHHHHCCCCCCCEEEEEEECCCCC
PELDGTLTRIAADLTKDQQSGAAYYVVRINLAERELARLEGKVLVPGMPVEAYIQNGVRT
CCCCHHHHHHHHHHHHHCCCCCEEEEEEEECHHHHHHHHCCCEECCCCCHHHHHHHHHHH
ALAYLRKPLEDQLARAFRQR
HHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure 
TQPAVTEDRRSAPFRDVRNAVIIGVAALAIVISTAGVWAVTAPIASAVIAPAQVVVDSN
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHEEECCC
VRRIQHPTGGVVAGISVNDGDYVHAGDELLRLDETLPRANLALIENQLNQFWTRRARLQA
CHHHCCCCCCEEEEEEECCCCEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
EQNGRDAMPVPVELTGRTDEPAIAQIIEGETALLLRRREAITGQQSQLGERKSQIGEEIR
HCCCCCCCCCCEEECCCCCCHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GLAAQIDSKREQIRLIQRELEGVRQLFDKNLIPYARLTALEREAARLTGEEGQLIADTAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEHHH
AKGRITETELQIIQLTQDQRREVATDLREVEIKIADLAERRIAAQDQLTRVVLRAPQDGL
CCCCCCHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
IHQKAVHTVGGVISPGEQLMLIVPKDSLVIEARVEPQMIDRLKPGQPAKLRFTAFDTAVT
HHHHHHHHHCCCCCCCCCEEEEECCCCEEEEEECCHHHHHHCCCCCCCEEEEEEECCCCC
PELDGTLTRIAADLTKDQQSGAAYYVVRINLAERELARLEGKVLVPGMPVEAYIQNGVRT
CCCCHHHHHHHHHHHHHCCCCCEEEEEEEECHHHHHHHHCCCEECCCCCHHHHHHHHHHH
ALAYLRKPLEDQLARAFRQR
HHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1427098; 10984043 [H]