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The map label for this gene is trpB

Identifier: 86747761

GI number: 86747761

Start: 720399

End: 721613

Strand: Reverse

Name: trpB

Synonym: RPB_0635

Alternate gene names: 86747761

Gene position: 721613-720399 (Counterclockwise)

Preceding gene: 86747762

Following gene: 86747760

Centisome position: 13.53

GC content: 66.67

Gene sequence:

>1215_bases
ATGAACCAGATCCTGCCGAACTCGTTTCGATCCGGTCCCGACGAGCGCGGGCATTTCGGCATCTTCGGCGGCCGCTTCGT
CGCCGAGACGCTGATGCCGCTGATCCTCGCGCTGGAAAAGGCCTACGCGGAAGCCAAGGACGATCCGGCGTTCCGCGCCG
AGATGGACGGCTACCTCAAGCACTATGTCGGCCGGCCGTCGCCGCTGTATTTCGCCGAGCGGCTGACCGAGCATTTCGGC
GGCGCCAAGATCTACTTCAAGCGCGAGGACCTCAACCACACCGGCGCCCACAAGGTGAACAACGTGCTCGGCCAGATCAT
GCTGGCGCGGCGGATGGGCAAGCCGCGGATCATCGCCGAAACCGGCGCCGGCATGCACGGCGTCGCCACCGCGACGATGT
GCGCGAAATTCGGCCTGCAATGCGTCGTCTATATGGGCGCGGTCGACGTCGACCGGCAGCAGCCCAACGTGCTGCGGATG
AAGGCGCTCGGCGCCGAAGTCCGCCCGGTGACGTCCGGCGCCGCCACGCTCAAGGACGCGATGAACGAGGCGCTGCGCGA
CTGGGTCACCAACGTCCACGACACGTTCTATTGCATCGGCACCGTCGCCGGCCCGCACCCCTATCCGATGATGGTGCGCG
ACTTCCAGGCGGTGATCGGCCAGGAAGTGCGCGCGCAGATCATGGAAGCCGAAGGCCGGCTGCCGGATTCGCTGATCGCC
TGCATCGGCGGCGGCTCCAATGCGATGGGACTGTTTCATCCCTTCCTGGATGATAGCAGCGTCGCGATCTACGGCGTCGA
GGCCGCGGGCCACGGCCTCAGCAAGCTGCATGCGGCGTCGATCGCCGGCGGCAAGCCCGGCGTTCTGCACGGCAACCGCA
CCTATCTGCTGATGGACACCGATGGCCAGATCCAGGAAGCGCATTCGATCTCGGCCGGCCTCGACTATCCGGGCATCGGC
CCGGAACACGCCTGGCTGCACGATGTCGGCCGCGTCGAGTTCATGTCCGCCACCGACACCGAGGCGCTCGACGCCTTCAA
GCTGTGCTGCCGGCTGGAGGGCATCATCCCGGCGCTGGAGCCGGCCCATGCGCTGGCGAAAGTCGGCGACCTCGCCCCGC
CCCTGCCGAAGGATCATGTGATGGTGCTCAACATGTCGGGCCGCGGCGACAAGGATCTCGCTTCGGTCGCCGAACATCTC
GGGGGCCAGTTCTGA

Upstream 100 bases:

>100_bases
GTGTCCTCCGGCGTCGAGACGGCGCCCGGCGTCAAAGATTCCGAATTGATCCGCAGCTTCATCCGCGCCACGCGCGCCAG
CGAAGAGACGATGACCTGAC

Downstream 100 bases:

>100_bases
TGACTACGCGTATCGACATCCGCTTCGCCCAGCTCAAGCGCGAAGGCCGCCCGGCCTTCGTCACCTTCGTGATGGCGGGC
GATCCCGACCTCGCCACCTC

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MNQILPNSFRSGPDERGHFGIFGGRFVAETLMPLILALEKAYAEAKDDPAFRAEMDGYLKHYVGRPSPLYFAERLTEHFG
GAKIYFKREDLNHTGAHKVNNVLGQIMLARRMGKPRIIAETGAGMHGVATATMCAKFGLQCVVYMGAVDVDRQQPNVLRM
KALGAEVRPVTSGAATLKDAMNEALRDWVTNVHDTFYCIGTVAGPHPYPMMVRDFQAVIGQEVRAQIMEAEGRLPDSLIA
CIGGGSNAMGLFHPFLDDSSVAIYGVEAAGHGLSKLHAASIAGGKPGVLHGNRTYLLMDTDGQIQEAHSISAGLDYPGIG
PEHAWLHDVGRVEFMSATDTEALDAFKLCCRLEGIIPALEPAHALAKVGDLAPPLPKDHVMVLNMSGRGDKDLASVAEHL
GGQF

Sequences:

>Translated_404_residues
MNQILPNSFRSGPDERGHFGIFGGRFVAETLMPLILALEKAYAEAKDDPAFRAEMDGYLKHYVGRPSPLYFAERLTEHFG
GAKIYFKREDLNHTGAHKVNNVLGQIMLARRMGKPRIIAETGAGMHGVATATMCAKFGLQCVVYMGAVDVDRQQPNVLRM
KALGAEVRPVTSGAATLKDAMNEALRDWVTNVHDTFYCIGTVAGPHPYPMMVRDFQAVIGQEVRAQIMEAEGRLPDSLIA
CIGGGSNAMGLFHPFLDDSSVAIYGVEAAGHGLSKLHAASIAGGKPGVLHGNRTYLLMDTDGQIQEAHSISAGLDYPGIG
PEHAWLHDVGRVEFMSATDTEALDAFKLCCRLEGIIPALEPAHALAKVGDLAPPLPKDHVMVLNMSGRGDKDLASVAEHL
GGQF
>Mature_404_residues
MNQILPNSFRSGPDERGHFGIFGGRFVAETLMPLILALEKAYAEAKDDPAFRAEMDGYLKHYVGRPSPLYFAERLTEHFG
GAKIYFKREDLNHTGAHKVNNVLGQIMLARRMGKPRIIAETGAGMHGVATATMCAKFGLQCVVYMGAVDVDRQQPNVLRM
KALGAEVRPVTSGAATLKDAMNEALRDWVTNVHDTFYCIGTVAGPHPYPMMVRDFQAVIGQEVRAQIMEAEGRLPDSLIA
CIGGGSNAMGLFHPFLDDSSVAIYGVEAAGHGLSKLHAASIAGGKPGVLHGNRTYLLMDTDGQIQEAHSISAGLDYPGIG
PEHAWLHDVGRVEFMSATDTEALDAFKLCCRLEGIIPALEPAHALAKVGDLAPPLPKDHVMVLNMSGRGDKDLASVAEHL
GGQF

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family

Homologues:

Organism=Escherichia coli, GI1787515, Length=381, Percent_Identity=53.2808398950131, Blast_Score=418, Evalue=1e-118,
Organism=Saccharomyces cerevisiae, GI6321412, Length=384, Percent_Identity=55.9895833333333, Blast_Score=451, Evalue=1e-127,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPB_RHOP2 (Q2J2G4)

Other databases:

- EMBL:   CP000250
- RefSeq:   YP_484257.1
- HSSP:   P0A2K1
- STRING:   Q2J2G4
- GeneID:   3908328
- GenomeReviews:   CP000250_GR
- KEGG:   rpb:RPB_0635
- eggNOG:   COG0133
- HOGENOM:   HBG303148
- OMA:   LKREDLC
- ProtClustDB:   PRK04346
- BioCyc:   RPAL316058:RPB_0635-MONOMER
- HAMAP:   MF_00133
- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026
- TIGRFAMs:   TIGR00263

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.2.1.20

Molecular weight: Translated: 43540; Mature: 43540

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQILPNSFRSGPDERGHFGIFGGRFVAETLMPLILALEKAYAEAKDDPAFRAEMDGYLK
CCCCCCCHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
HYVGRPSPLYFAERLTEHFGGAKIYFKREDLNHTGAHKVNNVLGQIMLARRMGKPRIIAE
HHCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEE
TGAGMHGVATATMCAKFGLQCVVYMGAVDVDRQQPNVLRMKALGAEVRPVTSGAATLKDA
CCCCCCHHHHHHHHHHHCCCEEEEECCEECCCCCCCEEEHHHCCCCCCCCCCHHHHHHHH
MNEALRDWVTNVHDTFYCIGTVAGPHPYPMMVRDFQAVIGQEVRAQIMEAEGRLPDSLIA
HHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHE
CIGGGSNAMGLFHPFLDDSSVAIYGVEAAGHGLSKLHAASIAGGKPGVLHGNRTYLLMDT
EECCCCCCCHHHHHCCCCCCEEEEEEHHCCCCHHHHHHHHCCCCCCCEEECCEEEEEECC
DGQIQEAHSISAGLDYPGIGPEHAWLHDVGRVEFMSATDTEALDAFKLCCRLEGIIPALE
CCCHHHHHHHHCCCCCCCCCCCHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCC
PAHALAKVGDLAPPLPKDHVMVLNMSGRGDKDLASVAEHLGGQF
HHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MNQILPNSFRSGPDERGHFGIFGGRFVAETLMPLILALEKAYAEAKDDPAFRAEMDGYLK
CCCCCCCHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
HYVGRPSPLYFAERLTEHFGGAKIYFKREDLNHTGAHKVNNVLGQIMLARRMGKPRIIAE
HHCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEE
TGAGMHGVATATMCAKFGLQCVVYMGAVDVDRQQPNVLRMKALGAEVRPVTSGAATLKDA
CCCCCCHHHHHHHHHHHCCCEEEEECCEECCCCCCCEEEHHHCCCCCCCCCCHHHHHHHH
MNEALRDWVTNVHDTFYCIGTVAGPHPYPMMVRDFQAVIGQEVRAQIMEAEGRLPDSLIA
HHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHE
CIGGGSNAMGLFHPFLDDSSVAIYGVEAAGHGLSKLHAASIAGGKPGVLHGNRTYLLMDT
EECCCCCCCHHHHHCCCCCCEEEEEEHHCCCCHHHHHHHHCCCCCCCEEECCEEEEEECC
DGQIQEAHSISAGLDYPGIGPEHAWLHDVGRVEFMSATDTEALDAFKLCCRLEGIIPALE
CCCHHHHHHHHCCCCCCCCCCCHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCC
PAHALAKVGDLAPPLPKDHVMVLNMSGRGDKDLASVAEHLGGQF
HHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA