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The map label for this gene is fur [H]

Identifier: 86747714

GI number: 86747714

Start: 660846

End: 661343

Strand: Direct

Name: fur [H]

Synonym: RPB_0588

Alternate gene names: 86747714

Gene position: 660846-661343 (Clockwise)

Preceding gene: 86747713

Following gene: 86747715

Centisome position: 12.39

GC content: 62.25

Gene sequence:

>498_bases
ATGGCACAAGTGCTCGTCGCTCCATCCCATTCAAACGATGCGTTGACGCCGATGTCCGATATGAAGGCCACTGATATGAA
GGCCACCGAAATCGAAGCCCGCTGTGCCGCCACCGGCATGCGCATGACGGAGCAGCGTCGCGTGATCGCGCGGGTGCTCG
CCGAGGCGGTCGACCATCCCGACGTCGAGGAGCTGTACACCCGCTGCGTCGCCGTCGACGACAAGATCTCGATCTCGACC
GTGTACCGCACCGTCAAGCTGTTCGAGGACGCCGGCATCATCGAGCGGCACGATTTCCGCGAGGGCCGCGCCCGCTACGA
GCAGATGCGCGACAGCCATCATGATCATCTGATCAATCTGCGCGACGGCAAGGTGATCGAGTTCACCAACGAGGAGATCG
AACTGCTACAGGCCGAGATCGCCCGCAAGCTCGGCTACAAGCTGGTCGATCACCGGCTCGAGCTGTATTGCGTCCCGCTC
GACGACGACAAGGCCTGA

Upstream 100 bases:

>100_bases
TTCGAGATCGTCGGTCGGCGCGAGCGTTACTACCGGCAGCCCGACGGCCAACAATTGAACGCATTGATAATGCGTCGCGA
CTTGTCCTAGTTTTCGCGCG

Downstream 100 bases:

>100_bases
GCTGCGAGCACGGCGCGCCGGCGCGTTGCCATCGAGGCGCGAAGTCGGCTATTGACCTCTGTCTCCGTCATGGCCGGGCA
TAGCCGTTGAAGAACGGCGT

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MAQVLVAPSHSNDALTPMSDMKATDMKATEIEARCAATGMRMTEQRRVIARVLAEAVDHPDVEELYTRCVAVDDKISIST
VYRTVKLFEDAGIIERHDFREGRARYEQMRDSHHDHLINLRDGKVIEFTNEEIELLQAEIARKLGYKLVDHRLELYCVPL
DDDKA

Sequences:

>Translated_165_residues
MAQVLVAPSHSNDALTPMSDMKATDMKATEIEARCAATGMRMTEQRRVIARVLAEAVDHPDVEELYTRCVAVDDKISIST
VYRTVKLFEDAGIIERHDFREGRARYEQMRDSHHDHLINLRDGKVIEFTNEEIELLQAEIARKLGYKLVDHRLELYCVPL
DDDKA
>Mature_164_residues
AQVLVAPSHSNDALTPMSDMKATDMKATEIEARCAATGMRMTEQRRVIARVLAEAVDHPDVEELYTRCVAVDDKISISTV
YRTVKLFEDAGIIERHDFREGRARYEQMRDSHHDHLINLRDGKVIEFTNEEIELLQAEIARKLGYKLVDHRLELYCVPLD
DDKA

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=119, Percent_Identity=44.5378151260504, Blast_Score=100, Evalue=4e-23,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 18913; Mature: 18782

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQVLVAPSHSNDALTPMSDMKATDMKATEIEARCAATGMRMTEQRRVIARVLAEAVDHP
CCEEEECCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCC
DVEELYTRCVAVDDKISISTVYRTVKLFEDAGIIERHDFREGRARYEQMRDSHHDHLINL
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEC
RDGKVIEFTNEEIELLQAEIARKLGYKLVDHRLELYCVPLDDDKA
CCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCC
>Mature Secondary Structure 
AQVLVAPSHSNDALTPMSDMKATDMKATEIEARCAATGMRMTEQRRVIARVLAEAVDHP
CEEEECCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCC
DVEELYTRCVAVDDKISISTVYRTVKLFEDAGIIERHDFREGRARYEQMRDSHHDHLINL
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEC
RDGKVIEFTNEEIELLQAEIARKLGYKLVDHRLELYCVPLDDDKA
CCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9835040 [H]