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The map label for this gene is cobS [H]

Identifier: 86747667

GI number: 86747667

Start: 605872

End: 606867

Strand: Direct

Name: cobS [H]

Synonym: RPB_0541

Alternate gene names: 86747667

Gene position: 605872-606867 (Clockwise)

Preceding gene: 86747665

Following gene: 86747668

Centisome position: 11.36

GC content: 63.65

Gene sequence:

>996_bases
ATGACCGCCGCCACGACCAAAGCCCAGGAGATCACCGGCCTGCCCGACATGAAGGTGTCGGTCCGCCAGGTCTTCGGCAT
CGACAGCGACCTCGAAGTTCCCGCCTTTTCCGAGGCCGATCCGCATGTGCCCGATGTCGACAGCGACTATCGCTTCGACC
GCGCCACCACGCTCGCGATTCTCGCCGGCTTCGCCCGCAATCGCCGCGTCATGGTGACGGGCTTCCACGGCACCGGCAAA
TCGACCCATATCGAGCAGGTTGCGGCCCGGCTGAACTGGCCCTGCGTCCGCGTCAATCTCGACAGCCACATCAGCCGCAT
CGATCTGGTCGGCAAGGACTCGATCGTGGTCCGCGACGGCAAGCAGGTCACCGAATTCCGCGACGGCATCCTGCCCTGGG
CGTTGCAGCACAATGTGGCATTGGTGTTCGACGAATACGATGCCGGCCGCCCCGACGTGATGTTCGTGATCCAGCGCGTG
CTGGAAGTCTCCGGCCGGCTGACGCTGCTCGACCAGAACAAGGTGATCAAGCCGCATCCGGCGTTCCGGCTGTTCGCCAC
CGCCAACACCATCGGCCTGGGTGATACCTCGGGCCTGTATCACGGCACGCAGCAGATCAACCAGGGCCAGATGGACCGCT
GGTCGATCGTCACCACGCTGAACTATCTGCCGCACGACGAGGAAGTCGAGATCGTGCTCGCCAAGGCCAAGCACTATCGC
AACCCGGAAGGGCGCGACATCGTCAACAAGATGGTGCGGCTCGCCGATCTCACCCGCAACGCCTTCGCCAACGGCGACCT
GTCGACGGTGATGAGCCCGCGCACGGTGATCACCTGGTCGGAGAACGCCGAGATCTTCGGCGACATCGGCTTCGCGTTCC
GCGTCACCTTCCTCAACAAATGCGACGAGCTGGAGCGCCCGCTGGTGGCCGAGTTCTATCAGCGCTGCTTCAACGCCGAG
CTGCCGGAAAGCTCGGTGAATGTTGCGATGACGTAA

Upstream 100 bases:

>100_bases
GCTTCTGCGGATCGCGGCGGTCTGCTAGGTTTAAATCCGCACTCAACCGCATCCACCACATAGATCGGGTTTCGGGCGCG
TCCGGGACCACGGAGGATTG

Downstream 100 bases:

>100_bases
AGCCGGGCCCTCTCCCCGGGTGGGAGAGGGTGCCTTCGCGGAGCGGGCGCCCGCCTGTTCACCACGGCGCTGTGAGGATT
GGCGATGACGACCAGTTCGA

Product: cobalt chelatase, pCobS small subunit

Products: NA

Alternate protein names: Hydrogenobyrinic acid a,c-diamide cobaltochelatase subunit CobS [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MTAATTKAQEITGLPDMKVSVRQVFGIDSDLEVPAFSEADPHVPDVDSDYRFDRATTLAILAGFARNRRVMVTGFHGTGK
STHIEQVAARLNWPCVRVNLDSHISRIDLVGKDSIVVRDGKQVTEFRDGILPWALQHNVALVFDEYDAGRPDVMFVIQRV
LEVSGRLTLLDQNKVIKPHPAFRLFATANTIGLGDTSGLYHGTQQINQGQMDRWSIVTTLNYLPHDEEVEIVLAKAKHYR
NPEGRDIVNKMVRLADLTRNAFANGDLSTVMSPRTVITWSENAEIFGDIGFAFRVTFLNKCDELERPLVAEFYQRCFNAE
LPESSVNVAMT

Sequences:

>Translated_331_residues
MTAATTKAQEITGLPDMKVSVRQVFGIDSDLEVPAFSEADPHVPDVDSDYRFDRATTLAILAGFARNRRVMVTGFHGTGK
STHIEQVAARLNWPCVRVNLDSHISRIDLVGKDSIVVRDGKQVTEFRDGILPWALQHNVALVFDEYDAGRPDVMFVIQRV
LEVSGRLTLLDQNKVIKPHPAFRLFATANTIGLGDTSGLYHGTQQINQGQMDRWSIVTTLNYLPHDEEVEIVLAKAKHYR
NPEGRDIVNKMVRLADLTRNAFANGDLSTVMSPRTVITWSENAEIFGDIGFAFRVTFLNKCDELERPLVAEFYQRCFNAE
LPESSVNVAMT
>Mature_330_residues
TAATTKAQEITGLPDMKVSVRQVFGIDSDLEVPAFSEADPHVPDVDSDYRFDRATTLAILAGFARNRRVMVTGFHGTGKS
THIEQVAARLNWPCVRVNLDSHISRIDLVGKDSIVVRDGKQVTEFRDGILPWALQHNVALVFDEYDAGRPDVMFVIQRVL
EVSGRLTLLDQNKVIKPHPAFRLFATANTIGLGDTSGLYHGTQQINQGQMDRWSIVTTLNYLPHDEEVEIVLAKAKHYRN
PEGRDIVNKMVRLADLTRNAFANGDLSTVMSPRTVITWSENAEIFGDIGFAFRVTFLNKCDELERPLVAEFYQRCFNAEL
PESSVNVAMT

Specific function: Catalyzes cobalt insertion in the corrin ring [H]

COG id: COG0714

COG function: function code R; MoxR-like ATPases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI24415404, Length=212, Percent_Identity=25, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323135, Length=164, Percent_Identity=28.0487804878049, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI161076560, Length=191, Percent_Identity=28.2722513089005, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI161076562, Length=191, Percent_Identity=28.2722513089005, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011704
- InterPro:   IPR006537 [H]

Pfam domain/function: PF07728 AAA_5 [H]

EC number: =6.6.1.2 [H]

Molecular weight: Translated: 37063; Mature: 36931

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAATTKAQEITGLPDMKVSVRQVFGIDSDLEVPAFSEADPHVPDVDSDYRFDRATTLAI
CCCCCCCHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LAGFARNRRVMVTGFHGTGKSTHIEQVAARLNWPCVRVNLDSHISRIDLVGKDSIVVRDG
HHHHHCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEHHHCCCEEEEECCCCEEEECC
KQVTEFRDGILPWALQHNVALVFDEYDAGRPDVMFVIQRVLEVSGRLTLLDQNKVIKPHP
CHHHHHHCCCCCEEECCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCEECCCC
AFRLFATANTIGLGDTSGLYHGTQQINQGQMDRWSIVTTLNYLPHDEEVEIVLAKAKHYR
CEEEEEECCEECCCCCCCCCCCHHHHCCCCCCCEEEEEEECCCCCCCCEEEEEEEHHHCC
NPEGRDIVNKMVRLADLTRNAFANGDLSTVMSPRTVITWSENAEIFGDIGFAFRVTFLNK
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCEEEEECCCCEEEEECCHHHHHHHHHH
CDELERPLVAEFYQRCFNAELPESSVNVAMT
HHHHCCCHHHHHHHHHCCCCCCCCCCCEEEC
>Mature Secondary Structure 
TAATTKAQEITGLPDMKVSVRQVFGIDSDLEVPAFSEADPHVPDVDSDYRFDRATTLAI
CCCCCCHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LAGFARNRRVMVTGFHGTGKSTHIEQVAARLNWPCVRVNLDSHISRIDLVGKDSIVVRDG
HHHHHCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEHHHCCCEEEEECCCCEEEECC
KQVTEFRDGILPWALQHNVALVFDEYDAGRPDVMFVIQRVLEVSGRLTLLDQNKVIKPHP
CHHHHHHCCCCCEEECCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCEECCCC
AFRLFATANTIGLGDTSGLYHGTQQINQGQMDRWSIVTTLNYLPHDEEVEIVLAKAKHYR
CEEEEEECCEECCCCCCCCCCCHHHHCCCCCCCEEEEEEECCCCCCCCEEEEEEEHHHCC
NPEGRDIVNKMVRLADLTRNAFANGDLSTVMSPRTVITWSENAEIFGDIGFAFRVTFLNK
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCEEEEECCCCEEEEECCHHHHHHHHHH
CDELERPLVAEFYQRCFNAELPESSVNVAMT
HHHHCCCHHHHHHHHHCCCCCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1917840 [H]