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The map label for this gene is plp [H]

Identifier: 86747655

GI number: 86747655

Start: 592060

End: 592980

Strand: Reverse

Name: plp [H]

Synonym: RPB_0529

Alternate gene names: 86747655

Gene position: 592980-592060 (Counterclockwise)

Preceding gene: 86747657

Following gene: 86747652

Centisome position: 11.12

GC content: 66.23

Gene sequence:

>921_bases
ATGACCCCTGCGTCACCCGCAGCCCGTTCGGCCCTGCGCTCCGGCATCATCAGCGCGGCCGCGACCGGTTGTCTCGCTTT
TGCGCTGCTCGCGAGCCCGATGGCGCGCGCCCAGGACGCCAACCCGGTGCTGGCGAAGGTGAACGGCGCTGAAATCCGCC
AGAGCGACGTCACCCTCGCCGAGGAAGAGCTCGGCCCGAGCCTGGCCCAGATGGACCCGGCGACCAAGAAGGAAAACGTC
CTGTCGTTCCTGATCGATATGAAGATCGTCGCCAAGGCCGCCGAGGACAAGAAGATCGCCGACCGTGCGGAGTTCAAGAA
GCGGCTCGAATTCGCCCGCAACCGCCTGCTGATGGACGATCTGCTCGGCGTCGAGGGCAAGGCCGCCACCACCGACGAGG
CGATGAAGAAGGTCTATGAGGACGCCGCCAAGCAGATTTCCGGCGAGCAGGAAGTCCACGCCCGCCACATCCTGGTCGAG
ACCGAGGACGAGGCCAAGGCGATCGCCGAGGAACTGAAGAAGGGCGCCGATTTCGCCGAGCTGGCGAAGAAGAAGTCCAA
GGACCCGGGCGCCTCCGACGGCGGCGATCTCGGCTTCTTCACCAAGGACCAGATGGTGCCGGAATTCTCCGCGGTGGCAT
TTGCGCTGGAGCCCGGCAAGATCTCCGACCCGGTGAAGAGCCAGTTCGGCTGGCACATCATCAAGGTCGAGGAGAAGCGC
AACCGCAAGCCGCCGACCTTCGACCAGGTCAAGCCGCAGATCGAGCAATACGTCACCCGCAAGGCGCAGTCGGACTACGT
CACGCAGTTGCGTCAGGCCGCCAAGGTCGAGCGGCTCGACAAGCCGGCCGAGCCGGCCGCTTCCCCCGCCGACGCGGCAA
AGCCGGCCGAGCCGGCGGCCAAGGCCCCGGCGAAGAAGTAA

Upstream 100 bases:

>100_bases
AATTCATCATTTTGACAGAGTTTTCGCGTTGCCAAGGCTCCGTGATTGGGTGACTGTCCCGCCGCCCCCGACACCCCGGC
TTTCAGAACAAGGATTTTCC

Downstream 100 bases:

>100_bases
TCTTCGCTTTCGGGCAAGTTGTGAATGATTTCAATGGCCGGGCTCGTCCCGGCCATTGTCGTTTCAGGTTGTCTTCGGCA
GCTTCGCCTTCAGCGCATAC

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase plp; Rotamase plp [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MTPASPAARSALRSGIISAAATGCLAFALLASPMARAQDANPVLAKVNGAEIRQSDVTLAEEELGPSLAQMDPATKKENV
LSFLIDMKIVAKAAEDKKIADRAEFKKRLEFARNRLLMDDLLGVEGKAATTDEAMKKVYEDAAKQISGEQEVHARHILVE
TEDEAKAIAEELKKGADFAELAKKKSKDPGASDGGDLGFFTKDQMVPEFSAVAFALEPGKISDPVKSQFGWHIIKVEEKR
NRKPPTFDQVKPQIEQYVTRKAQSDYVTQLRQAAKVERLDKPAEPAASPADAAKPAEPAAKAPAKK

Sequences:

>Translated_306_residues
MTPASPAARSALRSGIISAAATGCLAFALLASPMARAQDANPVLAKVNGAEIRQSDVTLAEEELGPSLAQMDPATKKENV
LSFLIDMKIVAKAAEDKKIADRAEFKKRLEFARNRLLMDDLLGVEGKAATTDEAMKKVYEDAAKQISGEQEVHARHILVE
TEDEAKAIAEELKKGADFAELAKKKSKDPGASDGGDLGFFTKDQMVPEFSAVAFALEPGKISDPVKSQFGWHIIKVEEKR
NRKPPTFDQVKPQIEQYVTRKAQSDYVTQLRQAAKVERLDKPAEPAASPADAAKPAEPAAKAPAKK
>Mature_305_residues
TPASPAARSALRSGIISAAATGCLAFALLASPMARAQDANPVLAKVNGAEIRQSDVTLAEEELGPSLAQMDPATKKENVL
SFLIDMKIVAKAAEDKKIADRAEFKKRLEFARNRLLMDDLLGVEGKAATTDEAMKKVYEDAAKQISGEQEVHARHILVET
EDEAKAIAEELKKGADFAELAKKKSKDPGASDGGDLGFFTKDQMVPEFSAVAFALEPGKISDPVKSQFGWHIIKVEEKRN
RKPPTFDQVKPQIEQYVTRKAQSDYVTQLRQAAKVERLDKPAEPAASPADAAKPAEPAAKAPAKK

Specific function: Ppiases Accelerate The Folding Of Proteins. It Prefers Amino Acid Residues With Hydrophobic Side Chains Like Leucine And Phenylalanine In The P1 Position Of The Peptides Substrates. [C]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Homo sapiens, GI38679892, Length=100, Percent_Identity=41, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1790211, Length=86, Percent_Identity=51.1627906976744, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1786238, Length=102, Percent_Identity=44.1176470588235, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786645, Length=178, Percent_Identity=30.8988764044944, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17537235, Length=100, Percent_Identity=42, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI21356303, Length=105, Percent_Identity=40, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 33063; Mature: 32932

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPASPAARSALRSGIISAAATGCLAFALLASPMARAQDANPVLAKVNGAEIRQSDVTLA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHCHHH
EEELGPSLAQMDPATKKENVLSFLIDMKIVAKAAEDKKIADRAEFKKRLEFARNRLLMDD
HHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGVEGKAATTDEAMKKVYEDAAKQISGEQEVHARHILVETEDEAKAIAEELKKGADFAE
HHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHEEEECCHHHHHHHHHHHCCCCHHH
LAKKKSKDPGASDGGDLGFFTKDQMVPEFSAVAFALEPGKISDPVKSQFGWHIIKVEEKR
HHHHHCCCCCCCCCCCCCCCCHHHHCCCHHHHEEEECCCCCCCHHHHHCCEEEEEEEHHC
NRKPPTFDQVKPQIEQYVTRKAQSDYVTQLRQAAKVERLDKPAEPAASPADAAKPAEPAA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
KAPAKK
CCCCCC
>Mature Secondary Structure 
TPASPAARSALRSGIISAAATGCLAFALLASPMARAQDANPVLAKVNGAEIRQSDVTLA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHCHHH
EEELGPSLAQMDPATKKENVLSFLIDMKIVAKAAEDKKIADRAEFKKRLEFARNRLLMDD
HHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGVEGKAATTDEAMKKVYEDAAKQISGEQEVHARHILVETEDEAKAIAEELKKGADFAE
HHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHEEEECCHHHHHHHHHHHCCCCHHH
LAKKKSKDPGASDGGDLGFFTKDQMVPEFSAVAFALEPGKISDPVKSQFGWHIIKVEEKR
HHHHHCCCCCCCCCCCCCCCCHHHHCCCHHHHEEEECCCCCCCHHHHHCCEEEEEEEHHC
NRKPPTFDQVKPQIEQYVTRKAQSDYVTQLRQAAKVERLDKPAEPAASPADAAKPAEPAA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
KAPAKK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA