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The map label for this gene is regB [H]

Identifier: 86747363

GI number: 86747363

Start: 270206

End: 271519

Strand: Reverse

Name: regB [H]

Synonym: RPB_0237

Alternate gene names: 86747363

Gene position: 271519-270206 (Counterclockwise)

Preceding gene: 86747364

Following gene: 86747362

Centisome position: 5.09

GC content: 64.76

Gene sequence:

>1314_bases
ATGTCGGCGTCCACATTCGTGCCGCGCCTCGGTGACGTGACTCCGGGCGACGATGCGACCGACCGCAAGAACATGGCGCT
GCTGATCCAGCTCCGCTGGACCGCGGTGATCGGTCAGATCGTCACCATCGGCGCGGTGCATTTGTGGCTCGGTGCCCCAT
TGCCGCTCGTGCCGATGGGCGCCGTCGTGCTCGGGCTGATCGCGCTCAATATCGCGAGCCTGGCATGGATGCGCTATCGC
GTCGCGATCAGCAATCGCGACCTGCTGGTCGCGCTGATCCTCGATGTCGTCGCGCTGACCGCTCTGCTTTATCTCAGCGG
CGGCATCACCAATCCGTTCACCTCGCTGTATCTGCTGCAGGTGACGCTCGGCGCGGTGCTGCTCGACAGCCGCTCGAGCT
GGTCGCTGGTGGCCGTCGTGTTCACGGCTTTCATCTGGCTGACCGAAGCATCGCGCCCGCTGGTGCTGCCGCCGGCCGCC
GGCGATCCGGTCAATCTCGCCGTCGCCGGCATGCTGATTGGCTTCGCGCTGAATGCCGTGCTGTTGGTGGTGTTCGTCAC
GCGGATTCATCGCAATCTGCGCGAGCGCGACGCGCATCTGGCGGCGTTGCGCCAGCATGCTGCGGAGCAGGACCACATCG
TGCGCATGGGCCTGCTCGCCTCCGGCGCCGCGCACGAACTCGGCACGCCGCTGGCGTCGGTGTCGGTCATTCTCAGCGAT
TGGCGCCGGATGCCGCAGATCATGGCCAATCGTGAGATTGCCGAAGACCTCGCCGAAATGGAGACGGCGCTGAAGCGTTG
CCAATCGATCGTCACCGGGATTCTGGTGTCGGCCGGCGAGGCGCGCGGTGAGGGATCGTCACCGACCACGGTGTCGGCGT
TCCTGTCGGCGCTCGCCGAGGAATGGCAGAATGCGCGATGCAAGACCACGCTGCACGTCGTCAACGTCTTCGGCGAGGAC
GTGCCGATCGTTTCGGACGTCACGTTGAAGCAGGCGATCTTCAACGTGTTGGACAATGCGTTCGAAGTGTCGCGCTACTG
GATCGAGCTGGTTGCAGAGCGCGACGGCGACAATCTGGTGCTGTCGATCAGCGATCGCGGTCCCGGTTTTCCGAAGGACA
TGCTGACGCAGATCGGCAAGCCGTATCAGTCGAGCAAGGGCCGGGCCGGCGGCGGCCTAGGCCTGTTCCTGGTCATGAAC
GTCGTGCGCAAGCTCGGCGGCTCGATCACCGCGGAAAACCTCCGCACCCGCGGCGCCAAGGTCAAGCTGGTGCTGCCGCT
TTCGACACTCGCGATCGGAAATCCATTTGATTGA

Upstream 100 bases:

>100_bases
CCGGGCCAAGAGGCGCAATCCGCCCTTGCAACAGGATCACATGCTGGACCGATCTCCGGGCACCGTTGACGACAAGGCCG
GCTGGAGGTCGCGACAAGAC

Downstream 100 bases:

>100_bases
AGAACGCTCCTTGATCGTCGTCGAGGACGACGCCGGATTCGCCCGCACGCTGAAGCGCTCGTTCGAGCGTCGCGGCTACG
AGGTGGTGCACGCCTCGACC

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Protein prrB [H]

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MSASTFVPRLGDVTPGDDATDRKNMALLIQLRWTAVIGQIVTIGAVHLWLGAPLPLVPMGAVVLGLIALNIASLAWMRYR
VAISNRDLLVALILDVVALTALLYLSGGITNPFTSLYLLQVTLGAVLLDSRSSWSLVAVVFTAFIWLTEASRPLVLPPAA
GDPVNLAVAGMLIGFALNAVLLVVFVTRIHRNLRERDAHLAALRQHAAEQDHIVRMGLLASGAAHELGTPLASVSVILSD
WRRMPQIMANREIAEDLAEMETALKRCQSIVTGILVSAGEARGEGSSPTTVSAFLSALAEEWQNARCKTTLHVVNVFGED
VPIVSDVTLKQAIFNVLDNAFEVSRYWIELVAERDGDNLVLSISDRGPGFPKDMLTQIGKPYQSSKGRAGGGLGLFLVMN
VVRKLGGSITAENLRTRGAKVKLVLPLSTLAIGNPFD

Sequences:

>Translated_437_residues
MSASTFVPRLGDVTPGDDATDRKNMALLIQLRWTAVIGQIVTIGAVHLWLGAPLPLVPMGAVVLGLIALNIASLAWMRYR
VAISNRDLLVALILDVVALTALLYLSGGITNPFTSLYLLQVTLGAVLLDSRSSWSLVAVVFTAFIWLTEASRPLVLPPAA
GDPVNLAVAGMLIGFALNAVLLVVFVTRIHRNLRERDAHLAALRQHAAEQDHIVRMGLLASGAAHELGTPLASVSVILSD
WRRMPQIMANREIAEDLAEMETALKRCQSIVTGILVSAGEARGEGSSPTTVSAFLSALAEEWQNARCKTTLHVVNVFGED
VPIVSDVTLKQAIFNVLDNAFEVSRYWIELVAERDGDNLVLSISDRGPGFPKDMLTQIGKPYQSSKGRAGGGLGLFLVMN
VVRKLGGSITAENLRTRGAKVKLVLPLSTLAIGNPFD
>Mature_436_residues
SASTFVPRLGDVTPGDDATDRKNMALLIQLRWTAVIGQIVTIGAVHLWLGAPLPLVPMGAVVLGLIALNIASLAWMRYRV
AISNRDLLVALILDVVALTALLYLSGGITNPFTSLYLLQVTLGAVLLDSRSSWSLVAVVFTAFIWLTEASRPLVLPPAAG
DPVNLAVAGMLIGFALNAVLLVVFVTRIHRNLRERDAHLAALRQHAAEQDHIVRMGLLASGAAHELGTPLASVSVILSDW
RRMPQIMANREIAEDLAEMETALKRCQSIVTGILVSAGEARGEGSSPTTVSAFLSALAEEWQNARCKTTLHVVNVFGEDV
PIVSDVTLKQAIFNVLDNAFEVSRYWIELVAERDGDNLVLSISDRGPGFPKDMLTQIGKPYQSSKGRAGGGLGLFLVMNV
VRKLGGSITAENLRTRGAKVKLVLPLSTLAIGNPFD

Specific function: Member of the two-component regulatory system RegB/RegA. Involved in the positive regulation of photosynthesis gene expression in response to anaerobiosis. Also involved in positive regulation of the cbbI and cbbII Calvin cycle CO2 fixation operons, as we

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=264, Percent_Identity=26.1363636363636, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 46900; Mature: 46769

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS50109 HIS_KIN ; PS00539 PYROKININ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASTFVPRLGDVTPGDDATDRKNMALLIQLRWTAVIGQIVTIGAVHLWLGAPLPLVPMG
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
AVVLGLIALNIASLAWMRYRVAISNRDLLVALILDVVALTALLYLSGGITNPFTSLYLLQ
HHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
VTLGAVLLDSRSSWSLVAVVFTAFIWLTEASRPLVLPPAAGDPVNLAVAGMLIGFALNAV
HHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHH
LLVVFVTRIHRNLRERDAHLAALRQHAAEQDHIVRMGLLASGAAHELGTPLASVSVILSD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHH
WRRMPQIMANREIAEDLAEMETALKRCQSIVTGILVSAGEARGEGSSPTTVSAFLSALAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
EWQNARCKTTLHVVNVFGEDVPIVSDVTLKQAIFNVLDNAFEVSRYWIELVAERDGDNLV
HHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LSISDRGPGFPKDMLTQIGKPYQSSKGRAGGGLGLFLVMNVVRKLGGSITAENLRTRGAK
EEECCCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEHHHHHCCCCE
VKLVLPLSTLAIGNPFD
EEEEEEHHHHCCCCCCC
>Mature Secondary Structure 
SASTFVPRLGDVTPGDDATDRKNMALLIQLRWTAVIGQIVTIGAVHLWLGAPLPLVPMG
CCCCCCCCCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
AVVLGLIALNIASLAWMRYRVAISNRDLLVALILDVVALTALLYLSGGITNPFTSLYLLQ
HHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
VTLGAVLLDSRSSWSLVAVVFTAFIWLTEASRPLVLPPAAGDPVNLAVAGMLIGFALNAV
HHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHH
LLVVFVTRIHRNLRERDAHLAALRQHAAEQDHIVRMGLLASGAAHELGTPLASVSVILSD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHH
WRRMPQIMANREIAEDLAEMETALKRCQSIVTGILVSAGEARGEGSSPTTVSAFLSALAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
EWQNARCKTTLHVVNVFGEDVPIVSDVTLKQAIFNVLDNAFEVSRYWIELVAERDGDNLV
HHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LSISDRGPGFPKDMLTQIGKPYQSSKGRAGGGLGLFLVMNVVRKLGGSITAENLRTRGAK
EEECCCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEHHHHHCCCCE
VKLVLPLSTLAIGNPFD
EEEEEEHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7751278; 10358089 [H]