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The map label for this gene is gap-1 [H]

Identifier: 86608897

GI number: 86608897

Start: 1498813

End: 1499829

Strand: Direct

Name: gap-1 [H]

Synonym: CYB_1429

Alternate gene names: 86608897

Gene position: 1498813-1499829 (Clockwise)

Preceding gene: 86608895

Following gene: 86608903

Centisome position: 49.19

GC content: 61.65

Gene sequence:

>1017_bases
ATGACCACACGGGTAGCCATTAACGGATTTGGTCGCATTGGGCGGGCCTTCCTGCGGGTGCTGCTGTCTCAGCCAGCTCC
AGAGCTGGAGGTGGTGGCAGTCAATGACCTGACCGAACCCGACAACTTGGCCTACCTGCTCCAGTTCGACTCGGCCTATG
GGCGCCTTCCCCAAACCGTGAGCGCGGTGGACGGGCATCTGCAAATCGGCAACCACCTGAAAGTCCGAGTTTTGGCAGAG
CGGGATCCGGCACAACTGCCCTGGAAAGATCTGGGGGTTGACCTGGTGGTGGAATCAACCGGCTTGTTCACCAAACGAGA
GGGGGCGGCCAAACACCTGGAAGCCGGGGCCAAAAAGGTGATCATCTCTGCTCCCGCCAAAGGCCCCGACTTGACGGTGG
TGATGGGGGTCAACGACGACCAATACGACCCGGAGCGGCATCACATCGTCTCCAATGCTTCCTGCACCACCAATTGCTTG
GCGCCGCTGGCCAAGGTTTTGTTGGATCGCTTCGGCATCGAGACCGGCTTTCTCACCACTTGCCATGCCTATACCGCCAC
CCAGGCGATTGTGGATCGCCCGGATCCCAAAGATTACCGGCGGGGCCGCTCAGCAGCAGTGTCGATCGTGCCTTCCACCA
CCGGGGCCGCCACGGCAGTGGCCGAGGTTTTGCCCGCCCTGAGAGGGAAGATGGATGGCCTGGCGCTGCGGGTGCCCACC
TTGACCGGCTCGATTGTGGACTTTGTGGTGCGTACCGAGCAGCCCATCACCAGAGAAGCCGTCAACCAAGCCTTTGTCGA
GGCTGCAGAAGGCCCGCTGCGCGGCATCCTGGCCATTGCTCCACCGGAGATCGTCTCGGCGGATATCGTCGGGGATCCCC
ACTCTTCCATTGTGGATTTGGGATCCACCCTGACCTTAGGGGATCGCACGGTGAAGGTGCTCTCCTGGTATGACAACGAG
TACGGCTATGCGGCGCGGCTGGTGGATCTGGCGGCCAAAATCGGGGCTGCGCTGTAG

Upstream 100 bases:

>100_bases
GATGTGGATCCCGTTCTTCTTTTACCCTATCCCTAGGGGGGCAGCGTCTCCCATGCCGCGTCCCCTGATCCATCGTATAA
ACTGATACCGGAGGATTGCG

Downstream 100 bases:

>100_bases
GCGGCCATCCTTGTTGCGTTCAAGGCAAGGCTATTAGAACCGGATTTGCGGTGGGGCAGTTACGGTTCAGATGCGGTTGT
GGCCGGGGTTGCAGGCGATG

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MTTRVAINGFGRIGRAFLRVLLSQPAPELEVVAVNDLTEPDNLAYLLQFDSAYGRLPQTVSAVDGHLQIGNHLKVRVLAE
RDPAQLPWKDLGVDLVVESTGLFTKREGAAKHLEAGAKKVIISAPAKGPDLTVVMGVNDDQYDPERHHIVSNASCTTNCL
APLAKVLLDRFGIETGFLTTCHAYTATQAIVDRPDPKDYRRGRSAAVSIVPSTTGAATAVAEVLPALRGKMDGLALRVPT
LTGSIVDFVVRTEQPITREAVNQAFVEAAEGPLRGILAIAPPEIVSADIVGDPHSSIVDLGSTLTLGDRTVKVLSWYDNE
YGYAARLVDLAAKIGAAL

Sequences:

>Translated_338_residues
MTTRVAINGFGRIGRAFLRVLLSQPAPELEVVAVNDLTEPDNLAYLLQFDSAYGRLPQTVSAVDGHLQIGNHLKVRVLAE
RDPAQLPWKDLGVDLVVESTGLFTKREGAAKHLEAGAKKVIISAPAKGPDLTVVMGVNDDQYDPERHHIVSNASCTTNCL
APLAKVLLDRFGIETGFLTTCHAYTATQAIVDRPDPKDYRRGRSAAVSIVPSTTGAATAVAEVLPALRGKMDGLALRVPT
LTGSIVDFVVRTEQPITREAVNQAFVEAAEGPLRGILAIAPPEIVSADIVGDPHSSIVDLGSTLTLGDRTVKVLSWYDNE
YGYAARLVDLAAKIGAAL
>Mature_337_residues
TTRVAINGFGRIGRAFLRVLLSQPAPELEVVAVNDLTEPDNLAYLLQFDSAYGRLPQTVSAVDGHLQIGNHLKVRVLAER
DPAQLPWKDLGVDLVVESTGLFTKREGAAKHLEAGAKKVIISAPAKGPDLTVVMGVNDDQYDPERHHIVSNASCTTNCLA
PLAKVLLDRFGIETGFLTTCHAYTATQAIVDRPDPKDYRRGRSAAVSIVPSTTGAATAVAEVLPALRGKMDGLALRVPTL
TGSIVDFVVRTEQPITREAVNQAFVEAAEGPLRGILAIAPPEIVSADIVGDPHSSIVDLGSTLTLGDRTVKVLSWYDNEY
GYAARLVDLAAKIGAAL

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7657116, Length=328, Percent_Identity=49.390243902439, Blast_Score=321, Evalue=6e-88,
Organism=Homo sapiens, GI7669492, Length=334, Percent_Identity=47.3053892215569, Blast_Score=315, Evalue=5e-86,
Organism=Escherichia coli, GI1788079, Length=334, Percent_Identity=51.1976047904192, Blast_Score=334, Evalue=4e-93,
Organism=Escherichia coli, GI1789295, Length=331, Percent_Identity=42.9003021148036, Blast_Score=264, Evalue=5e-72,
Organism=Caenorhabditis elegans, GI17534677, Length=337, Percent_Identity=49.5548961424332, Blast_Score=322, Evalue=2e-88,
Organism=Caenorhabditis elegans, GI17534679, Length=337, Percent_Identity=49.2581602373887, Blast_Score=322, Evalue=2e-88,
Organism=Caenorhabditis elegans, GI32566163, Length=335, Percent_Identity=49.2537313432836, Blast_Score=315, Evalue=2e-86,
Organism=Caenorhabditis elegans, GI17568413, Length=335, Percent_Identity=49.2537313432836, Blast_Score=315, Evalue=3e-86,
Organism=Saccharomyces cerevisiae, GI6322409, Length=335, Percent_Identity=51.044776119403, Blast_Score=337, Evalue=2e-93,
Organism=Saccharomyces cerevisiae, GI6321631, Length=335, Percent_Identity=49.8507462686567, Blast_Score=327, Evalue=1e-90,
Organism=Saccharomyces cerevisiae, GI6322468, Length=335, Percent_Identity=48.955223880597, Blast_Score=327, Evalue=2e-90,
Organism=Drosophila melanogaster, GI85725000, Length=329, Percent_Identity=49.8480243161094, Blast_Score=313, Evalue=1e-85,
Organism=Drosophila melanogaster, GI22023983, Length=329, Percent_Identity=49.8480243161094, Blast_Score=313, Evalue=1e-85,
Organism=Drosophila melanogaster, GI17933600, Length=329, Percent_Identity=49.5440729483283, Blast_Score=313, Evalue=1e-85,
Organism=Drosophila melanogaster, GI18110149, Length=329, Percent_Identity=49.5440729483283, Blast_Score=313, Evalue=1e-85,
Organism=Drosophila melanogaster, GI19922412, Length=327, Percent_Identity=45.565749235474, Blast_Score=286, Evalue=2e-77,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36059; Mature: 35927

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRVAINGFGRIGRAFLRVLLSQPAPELEVVAVNDLTEPDNLAYLLQFDSAYGRLPQTV
CCEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEEECCHHCCCCCHH
SAVDGHLQIGNHLKVRVLAERDPAQLPWKDLGVDLVVESTGLFTKREGAAKHLEAGAKKV
HHCCCCEEECCCEEEEEEECCCCCCCCHHHCCEEEEEECCCCEECCCCHHHHHHCCCCEE
IISAPAKGPDLTVVMGVNDDQYDPERHHIVSNASCTTNCLAPLAKVLLDRFGIETGFLTT
EEECCCCCCCEEEEEECCCCCCCCHHHEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEE
CHAYTATQAIVDRPDPKDYRRGRSAAVSIVPSTTGAATAVAEVLPALRGKMDGLALRVPT
HHHHHHHHHHHCCCCCHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEECC
LTGSIVDFVVRTEQPITREAVNQAFVEAAEGPLRGILAIAPPEIVSADIVGDPHSSIVDL
CCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCHHEEECCCCCCCHHHHHC
GSTLTLGDRTVKVLSWYDNEYGYAARLVDLAAKIGAAL
CCEEEECCCEEEEEEEECCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTRVAINGFGRIGRAFLRVLLSQPAPELEVVAVNDLTEPDNLAYLLQFDSAYGRLPQTV
CEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEEECCHHCCCCCHH
SAVDGHLQIGNHLKVRVLAERDPAQLPWKDLGVDLVVESTGLFTKREGAAKHLEAGAKKV
HHCCCCEEECCCEEEEEEECCCCCCCCHHHCCEEEEEECCCCEECCCCHHHHHHCCCCEE
IISAPAKGPDLTVVMGVNDDQYDPERHHIVSNASCTTNCLAPLAKVLLDRFGIETGFLTT
EEECCCCCCCEEEEEECCCCCCCCHHHEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEE
CHAYTATQAIVDRPDPKDYRRGRSAAVSIVPSTTGAATAVAEVLPALRGKMDGLALRVPT
HHHHHHHHHHHCCCCCHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEECC
LTGSIVDFVVRTEQPITREAVNQAFVEAAEGPLRGILAIAPPEIVSADIVGDPHSSIVDL
CCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCHHEEECCCCCCCHHHHHC
GSTLTLGDRTVKVLSWYDNEYGYAARLVDLAAKIGAAL
CCEEEECCCEEEEEEEECCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2684782; 2227448; 2656407; 7408868; 193030; 3586018; 9175858 [H]