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The map label for this gene is rdgB [C]

Identifier: 86608312

GI number: 86608312

Start: 861973

End: 862584

Strand: Direct

Name: rdgB [C]

Synonym: CYB_0830

Alternate gene names: 86608312

Gene position: 861973-862584 (Clockwise)

Preceding gene: 86608311

Following gene: 86608313

Centisome position: 28.29

GC content: 61.6

Gene sequence:

>612_bases
ATGACCCGTCCTTTGATCTTGGCCAGCAGTAGCCCCGGCAAATGGCGCGAGTTCAATGCCTTTTTCCAGGCCCATGCCCC
TGCTTGGGAGCTGCGCCGCATGCCCTCAGAAATTGAGGTGGAAGAAACCGGCACCACCTTTGCCGAAAATGCCCTTCTCA
AAGCCAGAGCCGTGGCCAAGTCTCTGGGGGAGTGGGCCATTGCCGACGATTCCGGCCTAGCGGTAGAAGCCCTTGGCGGC
GTCCCTGGGATCCGCTCGGCTCGCTATGCCCCCAACGATGCTGCCCGCATCGAGCGGTTGCTCAGGGAAATGGAAGGGAT
CCCAAATCGCCGAGCCACCTTTCACTGCGCCATCGCCCTGGTGGATCCCCAAGGTGTAGTGCATGCCCTGGTGGAAGGGG
TATGCTCGGGAGAGATCTTGACCCAGCCGCGGGGAGAGGGGGGGTTTGGCTATGACCCCCTGTTTTGGGTGCCCGAAGTG
GGGCTAACCTTTGCCGAGATGAGCCCAGCTCAAAAAGAGGCCATCGGCCACCGAGGCCGAGCCTTGCGCGCCTTGAAAGC
GCAGTTGCCTCTCCTGGAGAAGCGTATGGGCTGGCTTGGATCCCAGGAATAG

Upstream 100 bases:

>100_bases
ATTAACACAGCCCTGCACAACATGGTTCTCGAGATCCATTAGGCAGGAAGCCCTTGGACAGCCTTCCGCCTCCTCAGATT
TCCACTCGTAGGAACCTTCC

Downstream 100 bases:

>100_bases
CATCCGATGTCCTGGCTGGGGAGCTGCTAGCATACAATAGTCCCTTCCCTTCGGGGGAGTGAAATTGAAAGCCGTCTTGC
CTTGGCAGCTGAGGGGAGCG

Product: non-canonical purine NTP pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 203; Mature: 202

Protein sequence:

>203_residues
MTRPLILASSSPGKWREFNAFFQAHAPAWELRRMPSEIEVEETGTTFAENALLKARAVAKSLGEWAIADDSGLAVEALGG
VPGIRSARYAPNDAARIERLLREMEGIPNRRATFHCAIALVDPQGVVHALVEGVCSGEILTQPRGEGGFGYDPLFWVPEV
GLTFAEMSPAQKEAIGHRGRALRALKAQLPLLEKRMGWLGSQE

Sequences:

>Translated_203_residues
MTRPLILASSSPGKWREFNAFFQAHAPAWELRRMPSEIEVEETGTTFAENALLKARAVAKSLGEWAIADDSGLAVEALGG
VPGIRSARYAPNDAARIERLLREMEGIPNRRATFHCAIALVDPQGVVHALVEGVCSGEILTQPRGEGGFGYDPLFWVPEV
GLTFAEMSPAQKEAIGHRGRALRALKAQLPLLEKRMGWLGSQE
>Mature_202_residues
TRPLILASSSPGKWREFNAFFQAHAPAWELRRMPSEIEVEETGTTFAENALLKARAVAKSLGEWAIADDSGLAVEALGGV
PGIRSARYAPNDAARIERLLREMEGIPNRRATFHCAIALVDPQGVVHALVEGVCSGEILTQPRGEGGFGYDPLFWVPEVG
LTFAEMSPAQKEAIGHRGRALRALKAQLPLLEKRMGWLGSQE

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Escherichia coli, GI1789324, Length=192, Percent_Identity=43.2291666666667, Blast_Score=138, Evalue=2e-34,
Organism=Drosophila melanogaster, GI19920712, Length=189, Percent_Identity=25.3968253968254, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 22129; Mature: 21997

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPLILASSSPGKWREFNAFFQAHAPAWELRRMPSEIEVEETGTTFAENALLKARAVAK
CCCCEEEECCCCCCHHHHHHHHHHCCCHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHH
SLGEWAIADDSGLAVEALGGVPGIRSARYAPNDAARIERLLREMEGIPNRRATFHCAIAL
HHCCEEEECCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEE
VDPQGVVHALVEGVCSGEILTQPRGEGGFGYDPLFWVPEVGLTFAEMSPAQKEAIGHRGR
ECCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCEECCCCCCCHHHCCHHHHHHHHHCHH
ALRALKAQLPLLEKRMGWLGSQE
HHHHHHHHCCHHHHHHCCCCCCC
>Mature Secondary Structure 
TRPLILASSSPGKWREFNAFFQAHAPAWELRRMPSEIEVEETGTTFAENALLKARAVAK
CCCEEEECCCCCCHHHHHHHHHHCCCHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHH
SLGEWAIADDSGLAVEALGGVPGIRSARYAPNDAARIERLLREMEGIPNRRATFHCAIAL
HHCCEEEECCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEE
VDPQGVVHALVEGVCSGEILTQPRGEGGFGYDPLFWVPEVGLTFAEMSPAQKEAIGHRGR
ECCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCEECCCCCCCHHHCCHHHHHHHHHCHH
ALRALKAQLPLLEKRMGWLGSQE
HHHHHHHHCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]