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The map label for this gene is 86361034

Identifier: 86361034

GI number: 86361034

Start: 341754

End: 343052

Strand: Reverse

Name: 86361034

Synonym: RHE_PF00304

Alternate gene names: NA

Gene position: 343052-341754 (Counterclockwise)

Preceding gene: 86361040

Following gene: 86361033

Centisome position: 53.39

GC content: 62.51

Gene sequence:

>1299_bases
GTGACAATTTCGGAACGCCAGCCGGGCAAGCACGCCTGGTTCAGCCATGATCGCCTTGGCATGTTCATCCATTGGGGCCT
TTATGCTTTGGGAGCCCGGCATGAGTGGTTGAAGAACCGCGAAGAGCTGAACGACGACCACTACCAGCGCTATTTCGAGA
ATTTCGATCCCGATCTCTACGATCCCAAGGCCTGGGCGCGCCGCGCGCGGCGTGCCGGCATGAAATACGTCGTGGTGACG
ACCAAGCACCACGAAGGCTTCTGCCTCTGGGACAGCAAGGTGACGGACTATAAAGCGCCGAACACGCCCTGCGGCAAGGA
TCTGCTGACGCCGCTGGTCGAAGCGTTTCGCGCCGAGGGGCTGAAGATCGGCTTCTACTATTCGCTGCTCGACTGGCATC
ACCCCGATTTCCCGATCGACGTTCACCACCCCTTGCGCAACCACCCCGAGGCCGCGGCGCTGAATGCCGGTCGCAACATC
GCCAATTATGCCGCCTATATGCGCGAGCAGGTGCGCGAGCTTCTGACCGGCTTCGGTCGCATCGACATCATTTGGTTCGA
TTTCAGCTATCCCGGCCGCGAATATCGCGGCCTGCCAGGCAAGGGCCGCGCCGATTGGGAAAGCGAGCGGCTGCTCGAAC
TTGTTCGCCAGCTGCAGCCCGAAATCATCGTCAACAACCGCCTCGACCTGCCGCCGGGCAAGCTGCCCGACGTGACGACG
CCTGAGCAGTATACGCCGCGCGTGGCACCCGCCATCGCCAGTCAGGGTGTGCTCTGGGAAGCCTGCCACACCTTTAGCGG
CTCATGGGGCTATCACCGCGACGAGGACAGCTGGAAGAGCCCGGAGCAGATCATCCAGCTGCTGATCGATTCCGTCGCGC
TCGGCGGCAACCTCCTGATGAATGTCGGCCCCACTGGCCGCGGCACCTTCGACGCCCGCGCCATCGCCGCGCTCGAGGTC
TACCAGAACTGGATGGAGGTCAATGGGCGCTCGATCTATGGCGCCGGTCCGTCCGAATTTCCCGTGCCGGCCGGCTGCCG
CTACACCCAACGTGGCAACCGCCTCTATCTGCATGTCTACAACTGGCCTTACCGCCACATCCATATCGAGGGCCTCGCCG
ACAGGATCGCCTATGCCCAGTTCCTGCACGATGCCAGCGAAGTGCGCTGGCTCAGCCAGACGAAGGACGTGGATTCCAAT
ATCGGCGTGATGGTGCCGGAGGGCATGATCACGCTCGAACTGCCGGTCCGGCGACCTGATGTCACTGTCCCGGTGATCGA
GATCGTCCTCAAGGCGTGA

Upstream 100 bases:

>100_bases
TTTTCGAATTTCGACTTGACAGGCGCGGAGTCAAGCAAGATGATCAGCCACCGAACCGGTTCGATATGATATCGAGCCGG
GAAACAGGGAGGAGAAACCT

Downstream 100 bases:

>100_bases
ACTCGGTCGCATTCGCGTGTTCATTGCGTCATGGAGGGAGGAGAAACCCATGAAGGTTCTGAAGAAAACGCTTTTGCTTG
CCGCAGTCGGCGGCAGCCTC

Product: alpha-L-fucosidase protein

Products: L-fucose; alcohol

Alternate protein names: Glycoside Hydrolase Family; Glycosyl Hydrolase; Coagulation Factor 5/8 Type Domain Protein; Calx-Beta Domain-Containing Protein; Alpha-L-Fucosidase Protein; Exported Alpha-L-Fucosidase Protein; Alpha-1 3/4-Fucosidase; Lipoprotein; Exporte Hydrolase; Fucosidase; Exported Fucosidase; Alpha-L-Fucosidase Family Protein; Coagulation Factor 5/8 Type Domain-Containing Protein; Alpha-L-Fucosidase-Like Protein; Glycoside Hydrolase Family Alpha-L-Fucosidase; Ig Domain-Containing; Twin-Arginine Translocation Pathway Signal; Tat Pathway Signal Sequence Domain Protein; Glycosyl Hydrolase Alpha-L-Fucosidase; Exported Hydrolase; DS Domain-Containing Protein; Glycoside Hydrolase

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MTISERQPGKHAWFSHDRLGMFIHWGLYALGARHEWLKNREELNDDHYQRYFENFDPDLYDPKAWARRARRAGMKYVVVT
TKHHEGFCLWDSKVTDYKAPNTPCGKDLLTPLVEAFRAEGLKIGFYYSLLDWHHPDFPIDVHHPLRNHPEAAALNAGRNI
ANYAAYMREQVRELLTGFGRIDIIWFDFSYPGREYRGLPGKGRADWESERLLELVRQLQPEIIVNNRLDLPPGKLPDVTT
PEQYTPRVAPAIASQGVLWEACHTFSGSWGYHRDEDSWKSPEQIIQLLIDSVALGGNLLMNVGPTGRGTFDARAIAALEV
YQNWMEVNGRSIYGAGPSEFPVPAGCRYTQRGNRLYLHVYNWPYRHIHIEGLADRIAYAQFLHDASEVRWLSQTKDVDSN
IGVMVPEGMITLELPVRRPDVTVPVIEIVLKA

Sequences:

>Translated_432_residues
MTISERQPGKHAWFSHDRLGMFIHWGLYALGARHEWLKNREELNDDHYQRYFENFDPDLYDPKAWARRARRAGMKYVVVT
TKHHEGFCLWDSKVTDYKAPNTPCGKDLLTPLVEAFRAEGLKIGFYYSLLDWHHPDFPIDVHHPLRNHPEAAALNAGRNI
ANYAAYMREQVRELLTGFGRIDIIWFDFSYPGREYRGLPGKGRADWESERLLELVRQLQPEIIVNNRLDLPPGKLPDVTT
PEQYTPRVAPAIASQGVLWEACHTFSGSWGYHRDEDSWKSPEQIIQLLIDSVALGGNLLMNVGPTGRGTFDARAIAALEV
YQNWMEVNGRSIYGAGPSEFPVPAGCRYTQRGNRLYLHVYNWPYRHIHIEGLADRIAYAQFLHDASEVRWLSQTKDVDSN
IGVMVPEGMITLELPVRRPDVTVPVIEIVLKA
>Mature_431_residues
TISERQPGKHAWFSHDRLGMFIHWGLYALGARHEWLKNREELNDDHYQRYFENFDPDLYDPKAWARRARRAGMKYVVVTT
KHHEGFCLWDSKVTDYKAPNTPCGKDLLTPLVEAFRAEGLKIGFYYSLLDWHHPDFPIDVHHPLRNHPEAAALNAGRNIA
NYAAYMREQVRELLTGFGRIDIIWFDFSYPGREYRGLPGKGRADWESERLLELVRQLQPEIIVNNRLDLPPGKLPDVTTP
EQYTPRVAPAIASQGVLWEACHTFSGSWGYHRDEDSWKSPEQIIQLLIDSVALGGNLLMNVGPTGRGTFDARAIAALEVY
QNWMEVNGRSIYGAGPSEFPVPAGCRYTQRGNRLYLHVYNWPYRHIHIEGLADRIAYAQFLHDASEVRWLSQTKDVDSNI
GVMVPEGMITLELPVRRPDVTVPVIEIVLKA

Specific function: Unknown

COG id: COG3669

COG function: function code G; Alpha-L-fucosidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI119360348, Length=427, Percent_Identity=25.9953161592506, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI40068512, Length=353, Percent_Identity=28.328611898017, Blast_Score=119, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI71997700, Length=466, Percent_Identity=23.8197424892704, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24662717, Length=351, Percent_Identity=26.7806267806268, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI78706642, Length=351, Percent_Identity=26.7806267806268, Blast_Score=108, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.51

Molecular weight: Translated: 49629; Mature: 49498

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISERQPGKHAWFSHDRLGMFIHWGLYALGARHEWLKNREELNDDHYQRYFENFDPDLY
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHCCCCCCC
DPKAWARRARRAGMKYVVVTTKHHEGFCLWDSKVTDYKAPNTPCGKDLLTPLVEAFRAEG
CHHHHHHHHHHCCCEEEEEEEECCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
LKIGFYYSLLDWHHPDFPIDVHHPLRNHPEAAALNAGRNIANYAAYMREQVRELLTGFGR
EEEEEEEEEHHCCCCCCCEECCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
IDIIWFDFSYPGREYRGLPGKGRADWESERLLELVRQLQPEIIVNNRLDLPPGKLPDVTT
EEEEEEECCCCCHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCC
PEQYTPRVAPAIASQGVLWEACHTFSGSWGYHRDEDSWKSPEQIIQLLIDSVALGGNLLM
CCCCCCCHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEE
NVGPTGRGTFDARAIAALEVYQNWMEVNGRSIYGAGPSEFPVPAGCRYTQRGNRLYLHVY
ECCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEECCCCEEEEEEE
NWPYRHIHIEGLADRIAYAQFLHDASEVRWLSQTKDVDSNIGVMVPEGMITLELPVRRPD
CCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEEEECCCCCC
VTVPVIEIVLKA
CCHHHHHHHCCC
>Mature Secondary Structure 
TISERQPGKHAWFSHDRLGMFIHWGLYALGARHEWLKNREELNDDHYQRYFENFDPDLY
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHCCCCCCC
DPKAWARRARRAGMKYVVVTTKHHEGFCLWDSKVTDYKAPNTPCGKDLLTPLVEAFRAEG
CHHHHHHHHHHCCCEEEEEEEECCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
LKIGFYYSLLDWHHPDFPIDVHHPLRNHPEAAALNAGRNIANYAAYMREQVRELLTGFGR
EEEEEEEEEHHCCCCCCCEECCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
IDIIWFDFSYPGREYRGLPGKGRADWESERLLELVRQLQPEIIVNNRLDLPPGKLPDVTT
EEEEEEECCCCCHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCC
PEQYTPRVAPAIASQGVLWEACHTFSGSWGYHRDEDSWKSPEQIIQLLIDSVALGGNLLM
CCCCCCCHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEE
NVGPTGRGTFDARAIAALEVYQNWMEVNGRSIYGAGPSEFPVPAGCRYTQRGNRLYLHVY
ECCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEECCCCEEEEEEE
NWPYRHIHIEGLADRIAYAQFLHDASEVRWLSQTKDVDSNIGVMVPEGMITLELPVRRPD
CCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEEEECCCCCC
VTVPVIEIVLKA
CCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O; alpha-L-fucoside

Specific reaction: H2O + an alpha-L-fucoside = L-fucose + an alcohol

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA