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The map label for this gene is hypA

Identifier: 85860203

GI number: 85860203

Start: 2402834

End: 2403178

Strand: Direct

Name: hypA

Synonym: SYN_00595

Alternate gene names: 85860203

Gene position: 2402834-2403178 (Clockwise)

Preceding gene: 85860198

Following gene: 85860205

Centisome position: 75.58

GC content: 54.2

Gene sequence:

>345_bases
ATGCATGAACTGTCTCTCGTTTCATCGATTCTGGATATCATCGAGGATTATGCGGCACAAGACGGTTTTCGACGCGTCAA
CAACCTGCGTCTTTCCTGCGGCAGGCTGTCCGGTGTAGATCTTCAGTGCCTCCGGTTTGCCTTCGAGGTGCTGTCCAGGG
AGACCCGCTCCGAAGGAGCAACCCTCGAAATCGATTTCCTGCCGATTGTGATTTCCTGCCTGAACTGCGGAGAAGACACC
GAGGTGGAATACGTTGAGGCCTCCTGTCCGGAATGCGGCTCTGAAAATGTGCTGCTTGCAGGCGGGACAGAGGAACTTCG
TCTTCTTGAACTCGACGTGGATTGA

Upstream 100 bases:

>100_bases
GGGAGCAGCTTCCCGTTATTAATTCCTGATTATGAACGTTATTAAAAAAGGTTATGAGGTGAGGAACCCGGCCGCCACGG
CATTCGGCCGATAAAAACTC

Downstream 100 bases:

>100_bases
CCCGTCGTTCTGTGATAAAAATAGTTTACAAAACTCAACGGGAAGTTCGGGAGACTTTTCGGAAACGGGTTGAGCTCTGC
ATGGATTTCGAAGTTCTTTT

Product: hypA family hydrogenase nickel incorporation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 114; Mature: 114

Protein sequence:

>114_residues
MHELSLVSSILDIIEDYAAQDGFRRVNNLRLSCGRLSGVDLQCLRFAFEVLSRETRSEGATLEIDFLPIVISCLNCGEDT
EVEYVEASCPECGSENVLLAGGTEELRLLELDVD

Sequences:

>Translated_114_residues
MHELSLVSSILDIIEDYAAQDGFRRVNNLRLSCGRLSGVDLQCLRFAFEVLSRETRSEGATLEIDFLPIVISCLNCGEDT
EVEYVEASCPECGSENVLLAGGTEELRLLELDVD
>Mature_114_residues
MHELSLVSSILDIIEDYAAQDGFRRVNNLRLSCGRLSGVDLQCLRFAFEVLSRETRSEGATLEIDFLPIVISCLNCGEDT
EVEYVEASCPECGSENVLLAGGTEELRLLELDVD

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family

Homologues:

Organism=Escherichia coli, GI1789365, Length=102, Percent_Identity=35.2941176470588, Blast_Score=70, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYPA_SYNAS (Q2LVX4)

Other databases:

- EMBL:   CP000252
- RefSeq:   YP_462406.1
- STRING:   Q2LVX4
- GeneID:   3883638
- GenomeReviews:   CP000252_GR
- KEGG:   sat:SYN_00595
- NMPDR:   fig|56780.10.peg.2352
- eggNOG:   COG0375
- HOGENOM:   HBG688671
- OMA:   MHEMSLC
- PhylomeDB:   Q2LVX4
- BioCyc:   SACI56780:SYN_00595-MONOMER
- HAMAP:   MF_00213
- InterPro:   IPR000688
- InterPro:   IPR020538
- TIGRFAMs:   TIGR00100

Pfam domain/function: PF01155 HypA

EC number: NA

Molecular weight: Translated: 12600; Mature: 12600

Theoretical pI: Translated: 3.86; Mature: 3.86

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHELSLVSSILDIIEDYAAQDGFRRVNNLRLSCGRLSGVDLQCLRFAFEVLSRETRSEGA
CCHHHHHHHHHHHHHHHHHCHHHHHHHHCEEECCCCCCCCHHHHHHHHHHHHHHHCCCCC
TLEIDFLPIVISCLNCGEDTEVEYVEASCPECGSENVLLAGGTEELRLLELDVD
EEEEEHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEEEECCCCCEEEEEEECC
>Mature Secondary Structure
MHELSLVSSILDIIEDYAAQDGFRRVNNLRLSCGRLSGVDLQCLRFAFEVLSRETRSEGA
CCHHHHHHHHHHHHHHHHHCHHHHHHHHCEEECCCCCCCCHHHHHHHHHHHHHHHCCCCC
TLEIDFLPIVISCLNCGEDTEVEYVEASCPECGSENVLLAGGTEELRLLELDVD
EEEEEHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEEEECCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA