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The map label for this gene is dapB

Identifier: 85859279

GI number: 85859279

Start: 1466728

End: 1467534

Strand: Direct

Name: dapB

Synonym: SYN_02162

Alternate gene names: 85859279

Gene position: 1466728-1467534 (Clockwise)

Preceding gene: 85859278

Following gene: 85859280

Centisome position: 46.13

GC content: 52.29

Gene sequence:

>807_bases
ATGTTGAAAGCGATCGTGACCGGGGGCGGCGGAAAAATGGGTGCCCGGATTATCAGTTTGCTTGAAGAAGAGGGAGGCAT
GCAACTGACAGGGGTCGTCGAAAAAAAGGACCATCCTGCCGCGGGAAAAGACATTGGTGAATTCCTCGGATCGGGAAAGC
GGGGGATCGTAATCCAAAGCGATCTCGGTTTCTGCATCGCCGGGGGGGATGTGATTATCGATTTTACAAGCCACGAAGCT
TCGATGCGACATATGGAAATGGCTGCGGAACATAAACGGCCCATCGTGATCGGCAGCACAGGATTTTCCGCTGATGAAAT
GGACAGGATACGGAAGTTCGCTCAGAATGTTCCCTGTGTTCTTGCACCAAACATGAGCGTCGGCGTGAATGTGATGTTCA
AGCTTCTTAAAATTGTTGCAGAAACTCTGGGTGACGACTATGATGTTGAAATTCTGGAAGTTCACCACCGTCTTAAAAAG
GATGCCCCAAGCGGAACGGCCCTGAAAATGGCTCAGGTTGTTGCGGAGGCGCTGGGTCGGGAACTGGATGAAGTTGGAAT
CTATGAACGTAAAGGGCTCATCGGTGAACGATCAAAAAAAGAAATCGGCATCCAGGCTCTGCGGGCAGGCGATATCGTGG
GAGAACACACAGTGATATTCGGTGCGGTGGGCGAGAGACTTGAACTGATTCATCGCGCGCACAGCAGAGACAATTTTGCC
CGAGGCGCCATCCGCGCGGCAAAATGGGTGGTCAGGCAGGAACCGGGACTCTATGATATGCAGGATGTCCTCGGGTTCCG
ATCCTGA

Upstream 100 bases:

>100_bases
CTATGGCCTCATCGGGTGAAAAATTTATCTGTGAGGCGATTTCTCATTTTCCCTGATTTCGGTATTCGTGTCAGGAATCG
TCAGTTCAAGGAGATAAGTT

Downstream 100 bases:

>100_bases
AAAAGAACTTTGTATATCAGACCATGGTCAGTGAGCTGTGGATAAAGCAGGGAATCCTTTGTGTGAAGAAGTTTTGGGGG
TCATTGCCTATATCGGCATC

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MLKAIVTGGGGKMGARIISLLEEEGGMQLTGVVEKKDHPAAGKDIGEFLGSGKRGIVIQSDLGFCIAGGDVIIDFTSHEA
SMRHMEMAAEHKRPIVIGSTGFSADEMDRIRKFAQNVPCVLAPNMSVGVNVMFKLLKIVAETLGDDYDVEILEVHHRLKK
DAPSGTALKMAQVVAEALGRELDEVGIYERKGLIGERSKKEIGIQALRAGDIVGEHTVIFGAVGERLELIHRAHSRDNFA
RGAIRAAKWVVRQEPGLYDMQDVLGFRS

Sequences:

>Translated_268_residues
MLKAIVTGGGGKMGARIISLLEEEGGMQLTGVVEKKDHPAAGKDIGEFLGSGKRGIVIQSDLGFCIAGGDVIIDFTSHEA
SMRHMEMAAEHKRPIVIGSTGFSADEMDRIRKFAQNVPCVLAPNMSVGVNVMFKLLKIVAETLGDDYDVEILEVHHRLKK
DAPSGTALKMAQVVAEALGRELDEVGIYERKGLIGERSKKEIGIQALRAGDIVGEHTVIFGAVGERLELIHRAHSRDNFA
RGAIRAAKWVVRQEPGLYDMQDVLGFRS
>Mature_268_residues
MLKAIVTGGGGKMGARIISLLEEEGGMQLTGVVEKKDHPAAGKDIGEFLGSGKRGIVIQSDLGFCIAGGDVIIDFTSHEA
SMRHMEMAAEHKRPIVIGSTGFSADEMDRIRKFAQNVPCVLAPNMSVGVNVMFKLLKIVAETLGDDYDVEILEVHHRLKK
DAPSGTALKMAQVVAEALGRELDEVGIYERKGLIGERSKKEIGIQALRAGDIVGEHTVIFGAVGERLELIHRAHSRDNFA
RGAIRAAKWVVRQEPGLYDMQDVLGFRS

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=267, Percent_Identity=44.5692883895131, Blast_Score=225, Evalue=3e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_SYNAS (Q2LTA0)

Other databases:

- EMBL:   CP000252
- RefSeq:   YP_461481.1
- HSSP:   Q9X1K8
- ProteinModelPortal:   Q2LTA0
- SMR:   Q2LTA0
- STRING:   Q2LTA0
- GeneID:   3884312
- GenomeReviews:   CP000252_GR
- KEGG:   sat:SYN_02162
- NMPDR:   fig|56780.10.peg.1420
- eggNOG:   COG0289
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- PhylomeDB:   Q2LTA0
- ProtClustDB:   CLSK2775536
- BioCyc:   SACI56780:SYN_02162-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 29069; Mature: 29069

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKAIVTGGGGKMGARIISLLEEEGGMQLTGVVEKKDHPAAGKDIGEFLGSGKRGIVIQS
CCEEEEECCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHCCCCCCEEEEC
DLGFCIAGGDVIIDFTSHEASMRHMEMAAEHKRPIVIGSTGFSADEMDRIRKFAQNVPCV
CCCEEEECCCEEEEECCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCEE
LAPNMSVGVNVMFKLLKIVAETLGDDYDVEILEVHHRLKKDAPSGTALKMAQVVAEALGR
ECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
ELDEVGIYERKGLIGERSKKEIGIQALRAGDIVGEHTVIFGAVGERLELIHRAHSRDNFA
HHHHCCCHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHCCCHHH
RGAIRAAKWVVRQEPGLYDMQDVLGFRS
HHHHHHHHHHHHCCCCCCCHHHHHCCCC
>Mature Secondary Structure
MLKAIVTGGGGKMGARIISLLEEEGGMQLTGVVEKKDHPAAGKDIGEFLGSGKRGIVIQS
CCEEEEECCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHCCCCCCEEEEC
DLGFCIAGGDVIIDFTSHEASMRHMEMAAEHKRPIVIGSTGFSADEMDRIRKFAQNVPCV
CCCEEEECCCEEEEECCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCEE
LAPNMSVGVNVMFKLLKIVAETLGDDYDVEILEVHHRLKKDAPSGTALKMAQVVAEALGR
ECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
ELDEVGIYERKGLIGERSKKEIGIQALRAGDIVGEHTVIFGAVGERLELIHRAHSRDNFA
HHHHCCCHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHCCCHHH
RGAIRAAKWVVRQEPGLYDMQDVLGFRS
HHHHHHHHHHHHCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA