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The map label for this gene is dapA [H]

Identifier: 85859278

GI number: 85859278

Start: 1465747

End: 1466646

Strand: Direct

Name: dapA [H]

Synonym: SYN_02161

Alternate gene names: 85859278

Gene position: 1465747-1466646 (Clockwise)

Preceding gene: 85859277

Following gene: 85859279

Centisome position: 46.1

GC content: 50.78

Gene sequence:

>900_bases
GTGAAGGAGGGCAACAGGAAAAGTATGTTTAAAGGAGCTATTGTCGCGATTGTGACGCCATTTAAGAATGGCGAGATTGA
TGAACCGGCATTGAGGGATTTGATTGAGTTTCAGATTGAGAACGGGACGGACGGAATTGTTCCTTGCGGGACGACGGGAG
AATCGGCAACGCTGTCTCACGAGGAACATGATCGGGTTATCGAAATCACTATAGATGCCGTCAGAAAAAGAGTCCCTGTA
ATTGCGGGCACTGGTTCGAACAGCACGGTAGAAGCCATGAGATTGACGAAACATGCTCATGAAGCCGGCGCCGATGGCGT
ACTGGTGGTTGCTCCCTATTATAATCGTCCGACACAGGAGGGACTTTATCAGCATTATAAGGCGCTGGCGGAAAGCGTTC
CGATTCCGATCATCCCTTATAATATTCCCAGCCGCACCGGCGTGAATATCCTTCCGGAAACGGTGGCCCGACTGGCGAAA
ATAAGCAACATCGTCGGTATAAAGGAAGCCTCAGGTTCCCTCAAACAGATGAATGACGTCATCCGATTGTGTGACGATGG
CTTTTCCGTTCTTTCGGGAGATGATTTTTTTACCCTGCCTCTGTTGACCCTGGGAGGAAAGGGTGTTATTTCAGTAATAT
CCAATGTTGCACCAGCTGATATGGCGTGTCTTGTCGACGCTTTCGAGGCCGGAAACATGAAGAAAGCACGGGCGATGCAT
GACAAGATGGTGCCCCTGGTCGACGCCTTGTTTATTGAAACCAATCCGACTCCGGTCAAGGCGGCTCTGGCCCTGATGGG
CAAAATTTCTGAAGATGTGCGGCTGCCGCTCTACCGCATGACGGAGACCAGTCGGGAGAAGCTGAAAAGAGTCATGCAGA
ACTATGGCCTCATCGGGTGA

Upstream 100 bases:

>100_bases
AGTATTATGTTGTGCGCAGACGGGAAACCTATGCCGATTTAATTTCGCATGAGGAAATCCCTGCGTTTTTGAAAAACAAG
GCGATATCCCGAACAGGAAA

Downstream 100 bases:

>100_bases
AAAATTTATCTGTGAGGCGATTTCTCATTTTCCCTGATTTCGGTATTCGTGTCAGGAATCGTCAGTTCAAGGAGATAAGT
TATGTTGAAAGCGATCGTGA

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MKEGNRKSMFKGAIVAIVTPFKNGEIDEPALRDLIEFQIENGTDGIVPCGTTGESATLSHEEHDRVIEITIDAVRKRVPV
IAGTGSNSTVEAMRLTKHAHEAGADGVLVVAPYYNRPTQEGLYQHYKALAESVPIPIIPYNIPSRTGVNILPETVARLAK
ISNIVGIKEASGSLKQMNDVIRLCDDGFSVLSGDDFFTLPLLTLGGKGVISVISNVAPADMACLVDAFEAGNMKKARAMH
DKMVPLVDALFIETNPTPVKAALALMGKISEDVRLPLYRMTETSREKLKRVMQNYGLIG

Sequences:

>Translated_299_residues
MKEGNRKSMFKGAIVAIVTPFKNGEIDEPALRDLIEFQIENGTDGIVPCGTTGESATLSHEEHDRVIEITIDAVRKRVPV
IAGTGSNSTVEAMRLTKHAHEAGADGVLVVAPYYNRPTQEGLYQHYKALAESVPIPIIPYNIPSRTGVNILPETVARLAK
ISNIVGIKEASGSLKQMNDVIRLCDDGFSVLSGDDFFTLPLLTLGGKGVISVISNVAPADMACLVDAFEAGNMKKARAMH
DKMVPLVDALFIETNPTPVKAALALMGKISEDVRLPLYRMTETSREKLKRVMQNYGLIG
>Mature_299_residues
MKEGNRKSMFKGAIVAIVTPFKNGEIDEPALRDLIEFQIENGTDGIVPCGTTGESATLSHEEHDRVIEITIDAVRKRVPV
IAGTGSNSTVEAMRLTKHAHEAGADGVLVVAPYYNRPTQEGLYQHYKALAESVPIPIIPYNIPSRTGVNILPETVARLAK
ISNIVGIKEASGSLKQMNDVIRLCDDGFSVLSGDDFFTLPLLTLGGKGVISVISNVAPADMACLVDAFEAGNMKKARAMH
DKMVPLVDALFIETNPTPVKAALALMGKISEDVRLPLYRMTETSREKLKRVMQNYGLIG

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=290, Percent_Identity=25.8620689655172, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI13540533, Length=301, Percent_Identity=28.9036544850498, Blast_Score=92, Evalue=5e-19,
Organism=Escherichia coli, GI1788823, Length=292, Percent_Identity=48.972602739726, Blast_Score=293, Evalue=1e-80,
Organism=Escherichia coli, GI87082415, Length=296, Percent_Identity=32.7702702702703, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1786463, Length=273, Percent_Identity=34.0659340659341, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1789620, Length=272, Percent_Identity=29.0441176470588, Blast_Score=120, Evalue=1e-28,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 32386; Mature: 32386

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00665 DHDPS_1 ; PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEGNRKSMFKGAIVAIVTPFKNGEIDEPALRDLIEFQIENGTDGIVPCGTTGESATLSH
CCCCCHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCC
EEHDRVIEITIDAVRKRVPVIAGTGSNSTVEAMRLTKHAHEAGADGVLVVAPYYNRPTQE
CCCCCEEEEEHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHH
GLYQHYKALAESVPIPIIPYNIPSRTGVNILPETVARLAKISNIVGIKEASGSLKQMNDV
HHHHHHHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCHHCCCHHHHHHHH
IRLCDDGFSVLSGDDFFTLPLLTLGGKGVISVISNVAPADMACLVDAFEAGNMKKARAMH
HHHHCCCCCCCCCCCEEEEHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHH
DKMVPLVDALFIETNPTPVKAALALMGKISEDVRLPLYRMTETSREKLKRVMQNYGLIG
HHHHHHHHHEEECCCCCHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKEGNRKSMFKGAIVAIVTPFKNGEIDEPALRDLIEFQIENGTDGIVPCGTTGESATLSH
CCCCCHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCC
EEHDRVIEITIDAVRKRVPVIAGTGSNSTVEAMRLTKHAHEAGADGVLVVAPYYNRPTQE
CCCCCEEEEEHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHH
GLYQHYKALAESVPIPIIPYNIPSRTGVNILPETVARLAKISNIVGIKEASGSLKQMNDV
HHHHHHHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCHHCCCHHHHHHHH
IRLCDDGFSVLSGDDFFTLPLLTLGGKGVISVISNVAPADMACLVDAFEAGNMKKARAMH
HHHHCCCCCCCCCCCEEEEHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHH
DKMVPLVDALFIETNPTPVKAALALMGKISEDVRLPLYRMTETSREKLKRVMQNYGLIG
HHHHHHHHHEEECCCCCHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA