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The map label for this gene is 85375126

Identifier: 85375126

GI number: 85375126

Start: 2323472

End: 2324653

Strand: Direct

Name: 85375126

Synonym: ELI_11495

Alternate gene names: NA

Gene position: 2323472-2324653 (Clockwise)

Preceding gene: 85375125

Following gene: 85375127

Centisome position: 76.12

GC content: 63.37

Gene sequence:

>1182_bases
ATGAGCAAAGAGTCCCGCGAATTCGACATCATCGTCTATGGCGCCACCGGCTATACCGGTCGCCTCGTCGCCGAACATTT
CGTACGCCAGTATGCGGGCCGCGACGATGCACCGAAGTGGGCCATGGCAGGGCGCAACAAGGCGAAGCTGGAGGATGTGC
GCACACTGATCGGCGCGCCCGATGAGACGCCGCTGGTGGTCGCCGACGCCGACAGCCGCGAAGCATTGGAAGCCATGTGC
AAGCGCACCAAGGTCGTGCTGACGACGGTCGGCCCGTACCAGCTTTACGGAGACGATCTGGTCGCCGCTTGCGTCGCCAC
CGGCACCGACTATGCCGACCTGTGCGGTGAGCCGGGCTGGATGCGCGAACAGATCGACAAGCACCATGAAGCCGCCAAGA
CCAGCGGCGCGCGGATCTGCTTTTCGAGCGGGTTCGATTCGATCCCCTTCGACCTCGGCGTCTTCATGCTGCAAAAGGAA
GCGAAGGAACGCTTCGGCAAGCCTGCCAGCCGGGTGAAGGGCCGCGTGCGCGGGATGCAGGGCACCTTCTCGGGCGGCAC
CGCCGCCAGCCTCACCGCGACGATGAAGTCGGTCGCCAAGAACCCCAAGCTGATCTCGATCCTGCAAAGCCCGTTCGGCC
TCACGCCAGGCTTCGAAGGGCCGAACCAGCCGAGCGGCCTGCTGCCGGAATATGACGAAGACACCGGCAAATGGGCCGCG
CCCTTCATCATGGCGACGATCAACACCAAAAACGTGCACCGCACCAATTTCCTGCTCGGCCATCCTTATGGCGAGGACTT
CAAATACGATGAGATGATGCTCACCAGCCCCGGCGATGCCGGCAAGGCTGCCGCCAATGCGGTCGCGGAAATGCTCAAGA
ACCCGTTCGGCGCGAAGCCGCCCAAACCCGGCGAGGGGCCGAGCGAGGAAGAGCGCGAAAACGGTTTCTACGATGTCCTC
TTCATCGGCAAAACCGATAGCGGCGAAGAGATCCGCTACGGCGTCACGGGCAAGTACGATCCCGGCTACGGCTCCACCAG
CCGGATGCTGGCAGAAACCGGCATGGCGCTGCTCCACAAAGATACGCCCGGCGGGGTCGGCACGCCGGGCTCTTTCCTCG
GCGAGAAACTGGTTGAAAGGCTTGAGGAAAACGCGGAGATTGCCTTCGCGGTCGAGAGCTGA

Upstream 100 bases:

>100_bases
CAGCCGTCAATTCGGGTTCTGAGGCGGGAACCCCCGCTGTCATAGCGGCTTTGACTCTCCGGACGCGCGCGCCCATGCAG
GGCCGCAAAGGAGAGACCCC

Downstream 100 bases:

>100_bases
CCGCGCGCGCTACCGGCGCGCGTTATTTGGGGAGAGACCATAATGGCCATGATCGCATCGATTGCAGGCCGCCTGATGCT
GGCGCTGCTGTTCATCCTCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MSKESREFDIIVYGATGYTGRLVAEHFVRQYAGRDDAPKWAMAGRNKAKLEDVRTLIGAPDETPLVVADADSREALEAMC
KRTKVVLTTVGPYQLYGDDLVAACVATGTDYADLCGEPGWMREQIDKHHEAAKTSGARICFSSGFDSIPFDLGVFMLQKE
AKERFGKPASRVKGRVRGMQGTFSGGTAASLTATMKSVAKNPKLISILQSPFGLTPGFEGPNQPSGLLPEYDEDTGKWAA
PFIMATINTKNVHRTNFLLGHPYGEDFKYDEMMLTSPGDAGKAAANAVAEMLKNPFGAKPPKPGEGPSEEERENGFYDVL
FIGKTDSGEEIRYGVTGKYDPGYGSTSRMLAETGMALLHKDTPGGVGTPGSFLGEKLVERLEENAEIAFAVES

Sequences:

>Translated_393_residues
MSKESREFDIIVYGATGYTGRLVAEHFVRQYAGRDDAPKWAMAGRNKAKLEDVRTLIGAPDETPLVVADADSREALEAMC
KRTKVVLTTVGPYQLYGDDLVAACVATGTDYADLCGEPGWMREQIDKHHEAAKTSGARICFSSGFDSIPFDLGVFMLQKE
AKERFGKPASRVKGRVRGMQGTFSGGTAASLTATMKSVAKNPKLISILQSPFGLTPGFEGPNQPSGLLPEYDEDTGKWAA
PFIMATINTKNVHRTNFLLGHPYGEDFKYDEMMLTSPGDAGKAAANAVAEMLKNPFGAKPPKPGEGPSEEERENGFYDVL
FIGKTDSGEEIRYGVTGKYDPGYGSTSRMLAETGMALLHKDTPGGVGTPGSFLGEKLVERLEENAEIAFAVES
>Mature_392_residues
SKESREFDIIVYGATGYTGRLVAEHFVRQYAGRDDAPKWAMAGRNKAKLEDVRTLIGAPDETPLVVADADSREALEAMCK
RTKVVLTTVGPYQLYGDDLVAACVATGTDYADLCGEPGWMREQIDKHHEAAKTSGARICFSSGFDSIPFDLGVFMLQKEA
KERFGKPASRVKGRVRGMQGTFSGGTAASLTATMKSVAKNPKLISILQSPFGLTPGFEGPNQPSGLLPEYDEDTGKWAAP
FIMATINTKNVHRTNFLLGHPYGEDFKYDEMMLTSPGDAGKAAANAVAEMLKNPFGAKPPKPGEGPSEEERENGFYDVLF
IGKTDSGEEIRYGVTGKYDPGYGSTSRMLAETGMALLHKDTPGGVGTPGSFLGEKLVERLEENAEIAFAVES

Specific function: Unknown

COG id: COG3268

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the saccharopine dehydrogenase family. Enoyl reductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI55770836, Length=163, Percent_Identity=38.6503067484663, Blast_Score=118, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI32567112, Length=205, Percent_Identity=33.1707317073171, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17560066, Length=205, Percent_Identity=33.1707317073171, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71991033, Length=253, Percent_Identity=30.8300395256917, Blast_Score=104, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24646278, Length=427, Percent_Identity=27.8688524590164, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24644140, Length=158, Percent_Identity=33.5443037974684, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24644142, Length=158, Percent_Identity=33.5443037974684, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI21356081, Length=158, Percent_Identity=33.5443037974684, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR005097 [H]

Pfam domain/function: PF03435 Saccharop_dh [H]

EC number: NA

Molecular weight: Translated: 42424; Mature: 42293

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKESREFDIIVYGATGYTGRLVAEHFVRQYAGRDDAPKWAMAGRNKAKLEDVRTLIGAP
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHCCC
DETPLVVADADSREALEAMCKRTKVVLTTVGPYQLYGDDLVAACVATGTDYADLCGEPGW
CCCCEEEECCCCHHHHHHHHHCCEEEEEECCCCEEHHHHHHHHHHHCCCCHHHHCCCCCH
MREQIDKHHEAAKTSGARICFSSGFDSIPFDLGVFMLQKEAKERFGKPASRVKGRVRGMQ
HHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCC
GTFSGGTAASLTATMKSVAKNPKLISILQSPFGLTPGFEGPNQPSGLLPEYDEDTGKWAA
CCCCCCCHHHHHHHHHHHHCCCCEEHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEC
PFIMATINTKNVHRTNFLLGHPYGEDFKYDEMMLTSPGDAGKAAANAVAEMLKNPFGAKP
CEEEEEECCCCCEECEEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCC
PKPGEGPSEEERENGFYDVLFIGKTDSGEEIRYGVTGKYDPGYGSTSRMLAETGMALLHK
CCCCCCCCHHHHHCCCEEEEEEECCCCCCCEEECCCCCCCCCCCCHHHHHHHHCHHEEEC
DTPGGVGTPGSFLGEKLVERLEENAEIAFAVES
CCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECC
>Mature Secondary Structure 
SKESREFDIIVYGATGYTGRLVAEHFVRQYAGRDDAPKWAMAGRNKAKLEDVRTLIGAP
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHCCC
DETPLVVADADSREALEAMCKRTKVVLTTVGPYQLYGDDLVAACVATGTDYADLCGEPGW
CCCCEEEECCCCHHHHHHHHHCCEEEEEECCCCEEHHHHHHHHHHHCCCCHHHHCCCCCH
MREQIDKHHEAAKTSGARICFSSGFDSIPFDLGVFMLQKEAKERFGKPASRVKGRVRGMQ
HHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCC
GTFSGGTAASLTATMKSVAKNPKLISILQSPFGLTPGFEGPNQPSGLLPEYDEDTGKWAA
CCCCCCCHHHHHHHHHHHHCCCCEEHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEC
PFIMATINTKNVHRTNFLLGHPYGEDFKYDEMMLTSPGDAGKAAANAVAEMLKNPFGAKP
CEEEEEECCCCCEECEEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCC
PKPGEGPSEEERENGFYDVLFIGKTDSGEEIRYGVTGKYDPGYGSTSRMLAETGMALLHK
CCCCCCCCHHHHHCCCEEEEEEECCCCCCCEEECCCCCCCCCCCCHHHHHHHHCHHEEEC
DTPGGVGTPGSFLGEKLVERLEENAEIAFAVES
CCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]