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The map label for this gene is yngJ [H]

Identifier: 85375125

GI number: 85375125

Start: 2322209

End: 2323393

Strand: Direct

Name: yngJ [H]

Synonym: ELI_11490

Alternate gene names: 85375125

Gene position: 2322209-2323393 (Clockwise)

Preceding gene: 85375123

Following gene: 85375126

Centisome position: 76.08

GC content: 64.81

Gene sequence:

>1185_bases
ATGACCACACCCCTGTTCGACCAGTGGCGCGCGCGCTCGCCGCACTACGACGCTACCCACGAAGCGGTTTGCGACAGCGT
CCGCGCCTTCGTCCGCCAAGAGATCATGCCGCATGTTGAGGAATGGGAGGCAGCCGGCGAATTGCCGCGCGAGCTGCATC
GCAAGGCGGCCGAAGCGGGGATCATCGGTGTCGGCTATCCCGAGCATCTCGGCGGTAGCGGGACGTTGGAGGAAAAGGGC
TGGGACCCGTTCCACTCGCTCGTCCAGTCGGAAGAGATGTGTCGCCCCGGCGCGGGCGGCATCCCCGCCTCGCTGCTGAC
CCACGGCATCGGACTGCCGCCGATCGTCGCTATGGGCAGCGACGAGTTGCAGCAGCGCATCGCGCCGCAAGTCCTGTCGG
GAGAGAAGATCATCTGCCTCGGCATTACCGAGCCGGGCGGTGGATCGGATGTCGCACAATTGAAGACGAAGGCCGAGCGG
CGCGGCGATCATTACGTGGTCAATGGCGCAAAGACGCTGATAACTTCGGGCATGCGCGCCGACTTTATCACGCTAGCGGT
GCGCACCGGCGGGGACGGGATGGGCGGGATCTCGCTGCTGCTGGTCGAGACCGATCGCCCGGGTGTCAGCCGCACGCCAC
TGCAGAAAATGGGCTGGCATTCCTCGGACACCGCGACAATCCATCTCGACGATGTCGAAGTGCCTGCCGAAAACCTGATC
GGGGAGGAAAACCACGGCTTCGGCGGGATCATGCGCAATTTCAACGGCGAGCGTCTGGGCATGGCGCAGCAGGCCGCCGC
TTACGCCCGACTGTGCTACGAAGATGCGCTCGACTGGGCCCGCGAGCGTGAGACCTTCGGCCGCCCGCTGGTGACGCGCC
AGGCGATCCGCCACAAGCTCGCGCGGATGCTGCAGATGATCAACGCGACGCAGGCGATGATCGACCACGCGGCATGGACG
GTGAAGGAAGACTGCGCCTTTCCCGGCGATTTCGCGCTGCTCAAGGTGCAGGCGACGCAGACCATGGAATATTGCGCGCG
CGAGGCGTGCCAGATCATGGGCGGTGCGAGCTTCGTGCGCGGCAACCGTGTCGAGCGCATCTATCGCGAGGTTCGGGTAA
TGGCGATCGGCGGTGGTTCGGAAGAGATCATGTACGATCTCGCCAGCCGTCAATTCGGGTTCTGA

Upstream 100 bases:

>100_bases
AACGAGCCGCTTTCTACGGCGGTTCCCACTACCGCGCGCAGCCGGTCGACAAGTCTCGACCATCGGCGATAGGGTGAGGA
CACGCGAAACGAGGATGCCC

Downstream 100 bases:

>100_bases
GGCGGGAACCCCCGCTGTCATAGCGGCTTTGACTCTCCGGACGCGCGCGCCCATGCAGGGCCGCAAAGGAGAGACCCCAT
GAGCAAAGAGTCCCGCGAAT

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MTTPLFDQWRARSPHYDATHEAVCDSVRAFVRQEIMPHVEEWEAAGELPRELHRKAAEAGIIGVGYPEHLGGSGTLEEKG
WDPFHSLVQSEEMCRPGAGGIPASLLTHGIGLPPIVAMGSDELQQRIAPQVLSGEKIICLGITEPGGGSDVAQLKTKAER
RGDHYVVNGAKTLITSGMRADFITLAVRTGGDGMGGISLLLVETDRPGVSRTPLQKMGWHSSDTATIHLDDVEVPAENLI
GEENHGFGGIMRNFNGERLGMAQQAAAYARLCYEDALDWARERETFGRPLVTRQAIRHKLARMLQMINATQAMIDHAAWT
VKEDCAFPGDFALLKVQATQTMEYCAREACQIMGGASFVRGNRVERIYREVRVMAIGGGSEEIMYDLASRQFGF

Sequences:

>Translated_394_residues
MTTPLFDQWRARSPHYDATHEAVCDSVRAFVRQEIMPHVEEWEAAGELPRELHRKAAEAGIIGVGYPEHLGGSGTLEEKG
WDPFHSLVQSEEMCRPGAGGIPASLLTHGIGLPPIVAMGSDELQQRIAPQVLSGEKIICLGITEPGGGSDVAQLKTKAER
RGDHYVVNGAKTLITSGMRADFITLAVRTGGDGMGGISLLLVETDRPGVSRTPLQKMGWHSSDTATIHLDDVEVPAENLI
GEENHGFGGIMRNFNGERLGMAQQAAAYARLCYEDALDWARERETFGRPLVTRQAIRHKLARMLQMINATQAMIDHAAWT
VKEDCAFPGDFALLKVQATQTMEYCAREACQIMGGASFVRGNRVERIYREVRVMAIGGGSEEIMYDLASRQFGF
>Mature_393_residues
TTPLFDQWRARSPHYDATHEAVCDSVRAFVRQEIMPHVEEWEAAGELPRELHRKAAEAGIIGVGYPEHLGGSGTLEEKGW
DPFHSLVQSEEMCRPGAGGIPASLLTHGIGLPPIVAMGSDELQQRIAPQVLSGEKIICLGITEPGGGSDVAQLKTKAERR
GDHYVVNGAKTLITSGMRADFITLAVRTGGDGMGGISLLLVETDRPGVSRTPLQKMGWHSSDTATIHLDDVEVPAENLIG
EENHGFGGIMRNFNGERLGMAQQAAAYARLCYEDALDWARERETFGRPLVTRQAIRHKLARMLQMINATQAMIDHAAWTV
KEDCAFPGDFALLKVQATQTMEYCAREACQIMGGASFVRGNRVERIYREVRVMAIGGGSEEIMYDLASRQFGF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=383, Percent_Identity=32.1148825065274, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI187960098, Length=373, Percent_Identity=32.7077747989276, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI4557231, Length=373, Percent_Identity=32.7077747989276, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI7656849, Length=371, Percent_Identity=31.266846361186, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI4557233, Length=382, Percent_Identity=29.3193717277487, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI21361497, Length=374, Percent_Identity=29.6791443850267, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI226958412, Length=372, Percent_Identity=27.9569892473118, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI4501859, Length=371, Percent_Identity=25.0673854447439, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI226958414, Length=395, Percent_Identity=27.5949367088608, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI76496475, Length=345, Percent_Identity=30.7246376811594, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI4557235, Length=345, Percent_Identity=30.7246376811594, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI4503943, Length=334, Percent_Identity=29.3413173652695, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI7669494, Length=334, Percent_Identity=29.3413173652695, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI38505218, Length=278, Percent_Identity=24.4604316546763, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI87081958, Length=350, Percent_Identity=33.7142857142857, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1786223, Length=360, Percent_Identity=28.8888888888889, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI87082384, Length=337, Percent_Identity=27.299703264095, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17505929, Length=374, Percent_Identity=31.8181818181818, Blast_Score=192, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI17551932, Length=381, Percent_Identity=30.9711286089239, Blast_Score=187, Evalue=9e-48,
Organism=Caenorhabditis elegans, GI17570075, Length=374, Percent_Identity=30.7486631016043, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17569725, Length=393, Percent_Identity=29.7709923664122, Blast_Score=165, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17538396, Length=367, Percent_Identity=28.6103542234332, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17534899, Length=382, Percent_Identity=29.0575916230367, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17508101, Length=371, Percent_Identity=25.8760107816712, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17533517, Length=378, Percent_Identity=28.8359788359788, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI71985184, Length=356, Percent_Identity=28.3707865168539, Blast_Score=144, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI17506239, Length=368, Percent_Identity=25.2717391304348, Blast_Score=144, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI71985192, Length=285, Percent_Identity=29.8245614035088, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI71990804, Length=285, Percent_Identity=26.6666666666667, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71982178, Length=279, Percent_Identity=24.3727598566308, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17534353, Length=337, Percent_Identity=26.7062314540059, Blast_Score=104, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI32563615, Length=237, Percent_Identity=27.8481012658228, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24660351, Length=372, Percent_Identity=31.7204301075269, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI21356377, Length=367, Percent_Identity=29.4277929155313, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI21355753, Length=370, Percent_Identity=30.2702702702703, Blast_Score=165, Evalue=5e-41,
Organism=Drosophila melanogaster, GI24646207, Length=367, Percent_Identity=28.8828337874659, Blast_Score=151, Evalue=8e-37,
Organism=Drosophila melanogaster, GI281363737, Length=342, Percent_Identity=29.5321637426901, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24666513, Length=362, Percent_Identity=27.6243093922652, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI19920834, Length=337, Percent_Identity=26.4094955489614, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 43160; Mature: 43028

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPLFDQWRARSPHYDATHEAVCDSVRAFVRQEIMPHVEEWEAAGELPRELHRKAAEAG
CCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHCC
IIGVGYPEHLGGSGTLEEKGWDPFHSLVQSEEMCRPGAGGIPASLLTHGIGLPPIVAMGS
EEECCCHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCEEECCC
DELQQRIAPQVLSGEKIICLGITEPGGGSDVAQLKTKAERRGDHYVVNGAKTLITSGMRA
HHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEECCHHHHHHCCCCC
DFITLAVRTGGDGMGGISLLLVETDRPGVSRTPLQKMGWHSSDTATIHLDDVEVPAENLI
CEEEEEEEECCCCCCCEEEEEEECCCCCCCCCCHHHHCCCCCCEEEEEECCCCCCHHHHC
GEENHGFGGIMRNFNGERLGMAQQAAAYARLCYEDALDWARERETFGRPLVTRQAIRHKL
CCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ARMLQMINATQAMIDHAAWTVKEDCAFPGDFALLKVQATQTMEYCAREACQIMGGASFVR
HHHHHHHHHHHHHHHHHHHEEHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCHHHC
GNRVERIYREVRVMAIGGGSEEIMYDLASRQFGF
CHHHHHHHHHHEEEEECCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
TTPLFDQWRARSPHYDATHEAVCDSVRAFVRQEIMPHVEEWEAAGELPRELHRKAAEAG
CCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHCC
IIGVGYPEHLGGSGTLEEKGWDPFHSLVQSEEMCRPGAGGIPASLLTHGIGLPPIVAMGS
EEECCCHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCEEECCC
DELQQRIAPQVLSGEKIICLGITEPGGGSDVAQLKTKAERRGDHYVVNGAKTLITSGMRA
HHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEECCHHHHHHCCCCC
DFITLAVRTGGDGMGGISLLLVETDRPGVSRTPLQKMGWHSSDTATIHLDDVEVPAENLI
CEEEEEEEECCCCCCCEEEEEEECCCCCCCCCCHHHHCCCCCCEEEEEECCCCCCHHHHC
GEENHGFGGIMRNFNGERLGMAQQAAAYARLCYEDALDWARERETFGRPLVTRQAIRHKL
CCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ARMLQMINATQAMIDHAAWTVKEDCAFPGDFALLKVQATQTMEYCAREACQIMGGASFVR
HHHHHHHHHHHHHHHHHHHEEHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCHHHC
GNRVERIYREVRVMAIGGGSEEIMYDLASRQFGF
CHHHHHHHHHHEEEEECCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]