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The map label for this gene is hflC [H]

Identifier: 85375094

GI number: 85375094

Start: 2292750

End: 2293595

Strand: Direct

Name: hflC [H]

Synonym: ELI_11335

Alternate gene names: 85375094

Gene position: 2292750-2293595 (Clockwise)

Preceding gene: 85375093

Following gene: 85375095

Centisome position: 75.11

GC content: 61.23

Gene sequence:

>846_bases
ATGGACAGCATCTGGCAGAATTATAAACTCCCGATCATCGCCATTATCGTGCTCGCGATCCTGGCCGCGATGAGCATCGT
CTTCGTCGGCGAAGACGAGCAGGCCGTGGTCCTTCAGGGTGGTGAACCGGTCAAGACGATCAACAAGTTCAATCCCGACG
AACCCTTCGGTGCGACCAACGCCGGGATCCAGTGGCACTTGCCACTCGTACAGCGTGTCCAGATCGTAGATCGGCGGATC
CTGGATCTCGACATGGAACGGCAGCAGGTCCTGACCAGCGACCAGCAGCGCCTGCAGGTCGATGCCTATGCCCGGTTCCG
GATCATCGACCCGATCGAAATGGTGCGAAACGCACGGACCGAAGGCAATGTTGCCAACCAGCTGGCACCGATCCTGACGT
CGGTCTTGCGGCAGGAACTCGGCCGCCGGACGTTTGCATCGTTGCTGACGGCAGAGCGCGGCAATGCGATGACCAACATT
CGCGATATTCTGGACCGGCAGGCGCGCCAGTATGGCGCGCAGGTGCTCGACGTTCGCATCAAGCGGGCCGACCTTCCCGA
TGGCACCCCGCTCGAAGCCGCTTTCACCCGCATGCAGTCCGACCGGCAGGAAGAGGCCGAGACGATCCGCGCCCAAGGTC
GCCGCGACGCGCAGATCATTCGCGCCGAGGCCGAAGGGCAGGCTGCGCGCATCTATGCGACGGCTTATGGCAAGGATCCC
GATTTCTACGATTTCTACCGCGCGATGCAGAGCTATCGCACGACATTCCAGAACAGCGAGTCGGAAAGCTCCTTCATCCT
GTCGCCGGACAACGAATATCTGAACCAGTTCCGCGGTCGGCGCTGA

Upstream 100 bases:

>100_bases
CCGACAAGACCGTGATCGAGGCCGACGGGGTTACGCCGTATCTGCCGCTCCCCGAAGTTCAGCGCCGCAACCGCGCGTCC
CAGGCGGAGGGTCAGTAATC

Downstream 100 bases:

>100_bases
TCGAACCGACTGGGTCGTCGGTCGACGACTACAATTGTCGTTAAACCGCGGTTCAGCGCCCGCGCGCTGAACACGGAAAT
CGACCCGGACCTGAAACCGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MDSIWQNYKLPIIAIIVLAILAAMSIVFVGEDEQAVVLQGGEPVKTINKFNPDEPFGATNAGIQWHLPLVQRVQIVDRRI
LDLDMERQQVLTSDQQRLQVDAYARFRIIDPIEMVRNARTEGNVANQLAPILTSVLRQELGRRTFASLLTAERGNAMTNI
RDILDRQARQYGAQVLDVRIKRADLPDGTPLEAAFTRMQSDRQEEAETIRAQGRRDAQIIRAEAEGQAARIYATAYGKDP
DFYDFYRAMQSYRTTFQNSESESSFILSPDNEYLNQFRGRR

Sequences:

>Translated_281_residues
MDSIWQNYKLPIIAIIVLAILAAMSIVFVGEDEQAVVLQGGEPVKTINKFNPDEPFGATNAGIQWHLPLVQRVQIVDRRI
LDLDMERQQVLTSDQQRLQVDAYARFRIIDPIEMVRNARTEGNVANQLAPILTSVLRQELGRRTFASLLTAERGNAMTNI
RDILDRQARQYGAQVLDVRIKRADLPDGTPLEAAFTRMQSDRQEEAETIRAQGRRDAQIIRAEAEGQAARIYATAYGKDP
DFYDFYRAMQSYRTTFQNSESESSFILSPDNEYLNQFRGRR
>Mature_281_residues
MDSIWQNYKLPIIAIIVLAILAAMSIVFVGEDEQAVVLQGGEPVKTINKFNPDEPFGATNAGIQWHLPLVQRVQIVDRRI
LDLDMERQQVLTSDQQRLQVDAYARFRIIDPIEMVRNARTEGNVANQLAPILTSVLRQELGRRTFASLLTAERGNAMTNI
RDILDRQARQYGAQVLDVRIKRADLPDGTPLEAAFTRMQSDRQEEAETIRAQGRRDAQIIRAEAEGQAARIYATAYGKDP
DFYDFYRAMQSYRTTFQNSESESSFILSPDNEYLNQFRGRR

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=315, Percent_Identity=25.3968253968254, Blast_Score=103, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17569497, Length=237, Percent_Identity=29.1139240506329, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 32069; Mature: 32069

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSIWQNYKLPIIAIIVLAILAAMSIVFVGEDEQAVVLQGGEPVKTINKFNPDEPFGATN
CCCCHHCCCCHHHHHHHHHHHHHHHEEEECCCCCEEEEECCCCHHHHHCCCCCCCCCCCC
AGIQWHLPLVQRVQIVDRRILDLDMERQQVLTSDQQRLQVDAYARFRIIDPIEMVRNART
CCCEEEHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHEEECCHHHHHHCCCC
EGNVANQLAPILTSVLRQELGRRTFASLLTAERGNAMTNIRDILDRQARQYGAQVLDVRI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KRADLPDGTPLEAAFTRMQSDRQEEAETIRAQGRRDAQIIRAEAEGQAARIYATAYGKDP
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEECCCCCEEEEEEEECCCCC
DFYDFYRAMQSYRTTFQNSESESSFILSPDNEYLNQFRGRR
CHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHCCCC
>Mature Secondary Structure
MDSIWQNYKLPIIAIIVLAILAAMSIVFVGEDEQAVVLQGGEPVKTINKFNPDEPFGATN
CCCCHHCCCCHHHHHHHHHHHHHHHEEEECCCCCEEEEECCCCHHHHHCCCCCCCCCCCC
AGIQWHLPLVQRVQIVDRRILDLDMERQQVLTSDQQRLQVDAYARFRIIDPIEMVRNART
CCCEEEHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHEEECCHHHHHHCCCC
EGNVANQLAPILTSVLRQELGRRTFASLLTAERGNAMTNIRDILDRQARQYGAQVLDVRI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KRADLPDGTPLEAAFTRMQSDRQEEAETIRAQGRRDAQIIRAEAEGQAARIYATAYGKDP
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEECCCCCEEEEEEEECCCCC
DFYDFYRAMQSYRTTFQNSESESSFILSPDNEYLNQFRGRR
CHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]