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The map label for this gene is aroC

Identifier: 85374916

GI number: 85374916

Start: 2118747

End: 2119844

Strand: Direct

Name: aroC

Synonym: ELI_10445

Alternate gene names: 85374916

Gene position: 2118747-2119844 (Clockwise)

Preceding gene: 85374913

Following gene: 85374917

Centisome position: 69.41

GC content: 65.85

Gene sequence:

>1098_bases
ATGAGCTGGAACACTTTCGGACGCGTGCTGCGCATGACCACCTGGGGCGAGAGCCACGGCCCGGCGATCGGTTGCGTGCT
CGACGGATGCCCGCCGGGGATCGCGCTGAGCGAGAGCGACATCCAGCCTTTTCTCGACGCGCGCCGCCCGGGGCAGAACA
AGTTCACGACGCAGCGCAAGGAACCGGATCAGGTCCGCATTCTGTCCGGCGTATTCGATGGTCAAGACGGAGTTCAACGC
ACCACCGGCACGCCGATCAGCCTGATGATCGAGAATGTTGACCAGCGCTCGAAGGACTATTCCGAAGTCGCCAAGGCCTA
TCGCCCCGGCCATGCCGATTATGCCTATGACGCCAAATACGGGTTCCGCGACTATCGTGGCGGCGGGCGGTCGAGCGCGC
GCGAGACCGCCATGCGGGTCGCGGCAGGCGCGGTGGCGCGGTTGATCATTCCCGACGTGACCATCACCGGCTATGTTCGC
GAGATCGGCGGAGATGCGATCGATGCCGCCCGGTTCGACAGTGACGCCATCGGCGAGAACCCCTTCTGGTGTCCCGACGC
GGATGCAGCGAAGCGGTGGGAAACACTGGTCGACGAGGCGCGCAAGGCCGGATCTTCGCTCGGTGCAGTCGTCGAATGCG
TCGCCGAAGGCGTGCCGGCCGGTTGGGGCGCGCCGATCTATGCCAAGCTCGACGGAGACCTCGGCGGCGCGATGATGAGC
ATCAATGCGGTGAAAGGCGTGGAGATCGGCGACGGATTCGACGCCGCGCGGCTGAGCGGCGAGCAGAATGCCGATCCGAT
GCGTCCTGCCGCGGAGGGAAGCGATGCCGGCCCCCGCTTCGAGGCCAACCATGCGGGCGGCATCTCGGGCGGAATCAGCA
CCGGCCAGCCGGTCACGTGCAAGGTCGCCTTCAAGCCGACAAGTTCTATCCTGACCCCGGTCGAAACCATCGACACCGAG
GGCAATGCCACCGAAATCCGCACCAAGGGCCGCCACGACCCGTGCGTCGGTATCCGGGGCACCCCTGTGGTCGAAGCGAT
GATGGCGCTGGTACTGGCCGATCACATGCTGCTCCACCGCGCCCAGTGCGGGCAATAA

Upstream 100 bases:

>100_bases
CGGCCTCGCCACCCTAGTGCGAGGTTCCGAAGTAGGAAAATTGCGCGCAGCCTCACTTTCACATTCTCGACAGGTGCCCG
CTTTGCGCTATGCACGCGGC

Downstream 100 bases:

>100_bases
CCGTCAAGCCCCGCTAATCGCTTTCCCCGGAAAGCCCGATTTCTGATTGAGTTTTTCGATTTTCGGAATCGAAACACTCC
GCTTTGCTGCGCCGCATCAA

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MSWNTFGRVLRMTTWGESHGPAIGCVLDGCPPGIALSESDIQPFLDARRPGQNKFTTQRKEPDQVRILSGVFDGQDGVQR
TTGTPISLMIENVDQRSKDYSEVAKAYRPGHADYAYDAKYGFRDYRGGGRSSARETAMRVAAGAVARLIIPDVTITGYVR
EIGGDAIDAARFDSDAIGENPFWCPDADAAKRWETLVDEARKAGSSLGAVVECVAEGVPAGWGAPIYAKLDGDLGGAMMS
INAVKGVEIGDGFDAARLSGEQNADPMRPAAEGSDAGPRFEANHAGGISGGISTGQPVTCKVAFKPTSSILTPVETIDTE
GNATEIRTKGRHDPCVGIRGTPVVEAMMALVLADHMLLHRAQCGQ

Sequences:

>Translated_365_residues
MSWNTFGRVLRMTTWGESHGPAIGCVLDGCPPGIALSESDIQPFLDARRPGQNKFTTQRKEPDQVRILSGVFDGQDGVQR
TTGTPISLMIENVDQRSKDYSEVAKAYRPGHADYAYDAKYGFRDYRGGGRSSARETAMRVAAGAVARLIIPDVTITGYVR
EIGGDAIDAARFDSDAIGENPFWCPDADAAKRWETLVDEARKAGSSLGAVVECVAEGVPAGWGAPIYAKLDGDLGGAMMS
INAVKGVEIGDGFDAARLSGEQNADPMRPAAEGSDAGPRFEANHAGGISGGISTGQPVTCKVAFKPTSSILTPVETIDTE
GNATEIRTKGRHDPCVGIRGTPVVEAMMALVLADHMLLHRAQCGQ
>Mature_364_residues
SWNTFGRVLRMTTWGESHGPAIGCVLDGCPPGIALSESDIQPFLDARRPGQNKFTTQRKEPDQVRILSGVFDGQDGVQRT
TGTPISLMIENVDQRSKDYSEVAKAYRPGHADYAYDAKYGFRDYRGGGRSSARETAMRVAAGAVARLIIPDVTITGYVRE
IGGDAIDAARFDSDAIGENPFWCPDADAAKRWETLVDEARKAGSSLGAVVECVAEGVPAGWGAPIYAKLDGDLGGAMMSI
NAVKGVEIGDGFDAARLSGEQNADPMRPAAEGSDAGPRFEANHAGGISGGISTGQPVTCKVAFKPTSSILTPVETIDTEG
NATEIRTKGRHDPCVGIRGTPVVEAMMALVLADHMLLHRAQCGQ

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=365, Percent_Identity=54.7945205479452, Blast_Score=380, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6321290, Length=377, Percent_Identity=42.1750663129974, Blast_Score=289, Evalue=6e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_ERYLH (Q2N810)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_458978.1
- HSSP:   P63611
- ProteinModelPortal:   Q2N810
- SMR:   Q2N810
- STRING:   Q2N810
- GeneID:   3869632
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_10445
- NMPDR:   fig|314225.3.peg.942
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- PhylomeDB:   Q2N810
- ProtClustDB:   PRK05382
- BioCyc:   ELIT314225:ELI_10445-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 38687; Mature: 38556

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWNTFGRVLRMTTWGESHGPAIGCVLDGCPPGIALSESDIQPFLDARRPGQNKFTTQRK
CCCCHHHHEEEEEECCCCCCCEEEEEECCCCCCCEECCCCCHHHHHCCCCCCCCCCCCCC
EPDQVRILSGVFDGQDGVQRTTGTPISLMIENVDQRSKDYSEVAKAYRPGHADYAYDAKY
CCCCEEEEHHHCCCCCCCHHCCCCCCEEEEHHHHHCCHHHHHHHHHHCCCCCCCEECCCC
GFRDYRGGGRSSARETAMRVAAGAVARLIIPDVTITGYVREIGGDAIDAARFDSDAIGEN
CCHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHCCCCCCCCC
PFWCPDADAAKRWETLVDEARKAGSSLGAVVECVAEGVPAGWGAPIYAKLDGDLGGAMMS
CCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEE
INAVKGVEIGDGFDAARLSGEQNADPMRPAAEGSDAGPRFEANHAGGISGGISTGQPVTC
EECCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
KVAFKPTSSILTPVETIDTEGNATEIRTKGRHDPCVGIRGTPVVEAMMALVLADHMLLHR
EEEECCCHHHHCCHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
AQCGQ
HHCCC
>Mature Secondary Structure 
SWNTFGRVLRMTTWGESHGPAIGCVLDGCPPGIALSESDIQPFLDARRPGQNKFTTQRK
CCCHHHHEEEEEECCCCCCCEEEEEECCCCCCCEECCCCCHHHHHCCCCCCCCCCCCCC
EPDQVRILSGVFDGQDGVQRTTGTPISLMIENVDQRSKDYSEVAKAYRPGHADYAYDAKY
CCCCEEEEHHHCCCCCCCHHCCCCCCEEEEHHHHHCCHHHHHHHHHHCCCCCCCEECCCC
GFRDYRGGGRSSARETAMRVAAGAVARLIIPDVTITGYVREIGGDAIDAARFDSDAIGEN
CCHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHCCCCCCCCC
PFWCPDADAAKRWETLVDEARKAGSSLGAVVECVAEGVPAGWGAPIYAKLDGDLGGAMMS
CCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEE
INAVKGVEIGDGFDAARLSGEQNADPMRPAAEGSDAGPRFEANHAGGISGGISTGQPVTC
EECCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
KVAFKPTSSILTPVETIDTEGNATEIRTKGRHDPCVGIRGTPVVEAMMALVLADHMLLHR
EEEECCCHHHHCCHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
AQCGQ
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA